The document summarizes the process for handling cytology specimens received in the laboratory. Specimens are checked for proper labeling and assigned an identification number. Conventional smears are smeared onto slides, stained, and screened. For liquid-based preparations, the sample is collected in preservative and processed using the ThinPrep 2000. This system disperses and filters cells, transferring them onto a slide which is then stained and screened. Proper handling and staining allows examination of cellular morphology.