SlideShare ist ein Scribd-Unternehmen logo
1 von 52
Hypoadrenalism Gus Brooks Ali Chakera Angus Jones
Scope of today's talk ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Primary hypoadrenalism Addison’s disease
A typical case ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
VE, 26♀ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
VE, 26♀ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Issues highlighted by case ,[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical questions ,[object Object],[object Object],[object Object],[object Object],[object Object]
What is primary hypoadrenalism?
A bit of history ,[object Object],[object Object],[object Object],[object Object],[object Object]
1 º  hypoadrenalism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Epidemiology ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Are there any cardinal symptoms and signs of primary hypoadrenalism?
A typical case ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Suspicion Symptoms  Signs  Laboratory results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical Suspicion Symptoms  Signs  Laboratory results ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Pitfalls in diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Other associations ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
How do we diagnose Addison’s disease?
VE, 26 ♀ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Short-synacthen test (SST) ,[object Object],[object Object],[object Object],[object Object],[object Object]
Underlying cause ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Causes of Addison’s disease ,[object Object],[object Object],[object Object],Infective ,[object Object],[object Object],[object Object],Bilateral adrenalectomy Haemorrhage / infarction Infiltration ,[object Object],[object Object],Drugs ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Causes of primary hypoadrenalism ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Management of hypoadrenalism
Management of hypoadrenalism +ve +ve -ve -ve
How do we treat primary hypoadrenalism?
VE, 26♀ ,[object Object],[object Object],[object Object]
Glucocorticoids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Glucocorticoid ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
The problem patient… ,[object Object]
[object Object],[object Object],[object Object],[object Object],Mineralocorticoids ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
What about the androgens? ,[object Object],[object Object],[object Object],[object Object],[object Object]
How should we monitor patients with primary hypoadrenalism?
VE, 26♀ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Patient Education ,[object Object],[object Object],[object Object],[object Object],[object Object]
Routine review ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Other tests ,[object Object],[object Object],[object Object],[object Object],[object Object]
How do you manage primary hypogonadism in an unwell patient
VE, 26♀ ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Recognising  a crisis ,[object Object],[object Object],[object Object],[object Object],[object Object]
Managing a crisis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Management of physiologically unwell patients ,[object Object],[object Object],[object Object]
 
Exeter surgical guidelines
Other situations
Pregnancy ,[object Object],[object Object],[object Object],[object Object],[object Object]
Exercise ,[object Object],[object Object]
 
Questions?
[object Object]

Weitere ähnliche Inhalte

Was ist angesagt?

Cushing's Syndrome and Addison's Disease
Cushing's Syndrome and Addison's DiseaseCushing's Syndrome and Addison's Disease
Cushing's Syndrome and Addison's Disease
meducationdotnet
 

Was ist angesagt? (20)

Cushing syndrome and addision disease
Cushing syndrome and addision diseaseCushing syndrome and addision disease
Cushing syndrome and addision disease
 
Cushing syndrome
Cushing syndromeCushing syndrome
Cushing syndrome
 
Addison’s disease
Addison’s diseaseAddison’s disease
Addison’s disease
 
Cushing's syndrome
Cushing's syndromeCushing's syndrome
Cushing's syndrome
 
Adrenal insufficiency
Adrenal insufficiencyAdrenal insufficiency
Adrenal insufficiency
 
Skin Manifestation of Diabetes
Skin Manifestation of DiabetesSkin Manifestation of Diabetes
Skin Manifestation of Diabetes
 
Diabetic Ketoacidosis
Diabetic KetoacidosisDiabetic Ketoacidosis
Diabetic Ketoacidosis
 
Adrenal gland diseases,Cushing syndrome,Addison disease and Pheochromocytoma
Adrenal gland diseases,Cushing syndrome,Addison disease and PheochromocytomaAdrenal gland diseases,Cushing syndrome,Addison disease and Pheochromocytoma
Adrenal gland diseases,Cushing syndrome,Addison disease and Pheochromocytoma
 
9. metabolic syndrome
9. metabolic syndrome9. metabolic syndrome
9. metabolic syndrome
 
Cushing syndrome and addison disease
Cushing syndrome and addison diseaseCushing syndrome and addison disease
Cushing syndrome and addison disease
 
Cushing syndrome
Cushing syndromeCushing syndrome
Cushing syndrome
 
adrenal glands disorder
adrenal glands disorderadrenal glands disorder
adrenal glands disorder
 
Cushing's Syndrome by Dr. Aryan
Cushing's Syndrome by Dr. AryanCushing's Syndrome by Dr. Aryan
Cushing's Syndrome by Dr. Aryan
 
Addison's Disease powerpoint
Addison's Disease powerpointAddison's Disease powerpoint
Addison's Disease powerpoint
 
Addison’s Disease
Addison’s DiseaseAddison’s Disease
Addison’s Disease
 
Hypothyrodism
HypothyrodismHypothyrodism
Hypothyrodism
 
Cushing's Syndrome and Addison's Disease
Cushing's Syndrome and Addison's DiseaseCushing's Syndrome and Addison's Disease
Cushing's Syndrome and Addison's Disease
 
Cushing's syndrome
Cushing's syndromeCushing's syndrome
Cushing's syndrome
 
DKA FINAL
DKA FINALDKA FINAL
DKA FINAL
 
Thyroid presentation
Thyroid presentationThyroid presentation
Thyroid presentation
 

Andere mochten auch (8)

Adrenal insufficiency
Adrenal insufficiencyAdrenal insufficiency
Adrenal insufficiency
 
Di, siadh and cerebral salt wasting syndrome
Di, siadh and cerebral salt wasting syndromeDi, siadh and cerebral salt wasting syndrome
Di, siadh and cerebral salt wasting syndrome
 
systemic inflammatory response syndrome (SIRS)
systemic inflammatory response syndrome (SIRS)systemic inflammatory response syndrome (SIRS)
systemic inflammatory response syndrome (SIRS)
 
Addison disease
Addison diseaseAddison disease
Addison disease
 
Hypocalcemia
HypocalcemiaHypocalcemia
Hypocalcemia
 
Adrenal Insufficiency
Adrenal InsufficiencyAdrenal Insufficiency
Adrenal Insufficiency
 
Adrenal insufficiency
Adrenal insufficiencyAdrenal insufficiency
Adrenal insufficiency
 
SIRS, MODS, Sepsis
SIRS, MODS, SepsisSIRS, MODS, Sepsis
SIRS, MODS, Sepsis
 

Ähnlich wie Hypoadrenalism

Disorders of the Adrenal Glands
Disorders of the Adrenal GlandsDisorders of the Adrenal Glands
Disorders of the Adrenal Glands
Patrick Carter
 
Endocrine week 4 pt
Endocrine week 4 ptEndocrine week 4 pt
Endocrine week 4 pt
iothman
 
Rhabdomyolysis Im Morning
Rhabdomyolysis Im MorningRhabdomyolysis Im Morning
Rhabdomyolysis Im Morning
aldiaz41
 
Disorders of the Adrenal Glands 2011
Disorders of the Adrenal Glands 2011Disorders of the Adrenal Glands 2011
Disorders of the Adrenal Glands 2011
Patrick Carter
 
Endocrine emergencies
Endocrine emergenciesEndocrine emergencies
Endocrine emergencies
Dr. Rubz
 

Ähnlich wie Hypoadrenalism (20)

Adrenal Crisis.pptx
Adrenal Crisis.pptxAdrenal Crisis.pptx
Adrenal Crisis.pptx
 
adrenalcrisis-220627010816-f7d5cddb.pdf
adrenalcrisis-220627010816-f7d5cddb.pdfadrenalcrisis-220627010816-f7d5cddb.pdf
adrenalcrisis-220627010816-f7d5cddb.pdf
 
Disorders of the Adrenal Glands
Disorders of the Adrenal GlandsDisorders of the Adrenal Glands
Disorders of the Adrenal Glands
 
Endocrine week 4 pt
Endocrine week 4 ptEndocrine week 4 pt
Endocrine week 4 pt
 
Dr Rajkumar
Dr Rajkumar Dr Rajkumar
Dr Rajkumar
 
Addison disease
Addison diseaseAddison disease
Addison disease
 
Rhabdomyolysis Im Morning
Rhabdomyolysis Im MorningRhabdomyolysis Im Morning
Rhabdomyolysis Im Morning
 
Disorders of the Adrenal Glands 2011
Disorders of the Adrenal Glands 2011Disorders of the Adrenal Glands 2011
Disorders of the Adrenal Glands 2011
 
Neuroendocrine emergencies
Neuroendocrine emergenciesNeuroendocrine emergencies
Neuroendocrine emergencies
 
adrenal insuf seminar.pptx
adrenal insuf seminar.pptxadrenal insuf seminar.pptx
adrenal insuf seminar.pptx
 
Endocrine emergencies
Endocrine emergenciesEndocrine emergencies
Endocrine emergencies
 
Endocrine emergencies
Endocrine emergenciesEndocrine emergencies
Endocrine emergencies
 
Endocrinology
EndocrinologyEndocrinology
Endocrinology
 
VECHAS CHARLE'S CASE PRESENTATION.pptx
VECHAS CHARLE'S CASE PRESENTATION.pptxVECHAS CHARLE'S CASE PRESENTATION.pptx
VECHAS CHARLE'S CASE PRESENTATION.pptx
 
Addison's Disease
Addison's DiseaseAddison's Disease
Addison's Disease
 
Adrenal disorder.pptx
Adrenal disorder.pptxAdrenal disorder.pptx
Adrenal disorder.pptx
 
Adrenal insufficiency.pptx
Adrenal insufficiency.pptxAdrenal insufficiency.pptx
Adrenal insufficiency.pptx
 
Thyroid crisis
Thyroid crisisThyroid crisis
Thyroid crisis
 
A Case of Polyglandular Autoimmune Syndrome - Type II
A Case of Polyglandular Autoimmune Syndrome - Type IIA Case of Polyglandular Autoimmune Syndrome - Type II
A Case of Polyglandular Autoimmune Syndrome - Type II
 
Endocrine Emergency Part 1
Endocrine Emergency Part 1Endocrine Emergency Part 1
Endocrine Emergency Part 1
 

Kürzlich hochgeladen

Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
9953056974 Low Rate Call Girls In Saket, Delhi NCR
 
College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...
College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...
College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...
perfect solution
 

Kürzlich hochgeladen (20)

VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
VIP Hyderabad Call Girls Bahadurpally 7877925207 ₹5000 To 25K With AC Room 💚😋
 
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Nagpur Just Call 9907093804 Top Class Call Girl Service Available
 
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
All Time Service Available Call Girls Marine Drive 📳 9820252231 For 18+ VIP C...
 
Call Girls Kochi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kochi Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Kochi Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Kochi Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Faridabad Just Call 9907093804 Top Class Call Girl Service Available
 
Call Girls Bareilly Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Bareilly Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Bareilly Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls Agra Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Agra Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Agra Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Agra Just Call 8250077686 Top Class Call Girl Service Available
 
Call Girls Ooty Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Ooty Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Ooty Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Ooty Just Call 8250077686 Top Class Call Girl Service Available
 
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
Best Rate (Patna ) Call Girls Patna ⟟ 8617370543 ⟟ High Class Call Girl In 5 ...
 
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
♛VVIP Hyderabad Call Girls Chintalkunta🖕7001035870🖕Riya Kappor Top Call Girl ...
 
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7Call Girls in Gagan Vihar (delhi) call me [🔝  9953056974 🔝] escort service 24X7
Call Girls in Gagan Vihar (delhi) call me [🔝 9953056974 🔝] escort service 24X7
 
Call Girls Tirupati Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Tirupati Just Call 8250077686 Top Class Call Girl Service AvailableCall Girls Tirupati Just Call 8250077686 Top Class Call Girl Service Available
Call Girls Tirupati Just Call 8250077686 Top Class Call Girl Service Available
 
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
Pondicherry Call Girls Book Now 9630942363 Top Class Pondicherry Escort Servi...
 
College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...
College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...
College Call Girls in Haridwar 9667172968 Short 4000 Night 10000 Best call gi...
 
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
Night 7k to 12k Navi Mumbai Call Girl Photo 👉 BOOK NOW 9833363713 👈 ♀️ night ...
 
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
Book Paid Powai Call Girls Mumbai 𖠋 9930245274 𖠋Low Budget Full Independent H...
 
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...Russian Call Girls Service  Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
Russian Call Girls Service Jaipur {8445551418} ❤️PALLAVI VIP Jaipur Call Gir...
 
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
(👑VVIP ISHAAN ) Russian Call Girls Service Navi Mumbai🖕9920874524🖕Independent...
 
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
Premium Bangalore Call Girls Jigani Dail 6378878445 Escort Service For Hot Ma...
 
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service AvailableCall Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
Call Girls Coimbatore Just Call 9907093804 Top Class Call Girl Service Available
 

Hypoadrenalism

Hinweis der Redaktion

  1. “ It will hardly be disputed that at the present moment, the functions of the supra renal capsules, and the influence they exercise in the general economy, are almost or altogether unknown. The large supply of blood which they receive from three separate sources; their numerous nerves, derived immediately from the semilunar ganglia and solar plexus; their early development in the fœtus; their unimpaired integrity to the latest period of life; and their peculiar gland-like structure; all point to the performance of some important office: nevertheless, beyond an ill-defined impression, found on a consideration of their ultimate organization, that, in common with the spleen, thymus and thyroid body, they in some way or other minister to the elaboration of the blood, I am not aware that any modern authority has ventured to assign to them any special function of influence whatever.”