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http://www.ashwagandha.tk
Adrenal Fatigue: A growing problem in the US. ACTS is the solution!
What is adrenal fatigue? What are the symptoms? What is the solution?
Adrenal fatigue occurs when adrenal glands are now capable of producing the healthy amount of
hormones the body needs. When exposed to prolonged stress the adrenal glands simply cannot
keep up. Adrenal fatigue is often the result of reoccurring stress such as infections, smoking,
poor eating habits, financial pressures or emotional stress. The most important hormone to help
the body deal with stress is cortisol. However, when the body produces too much cortisol in the
attempt to cope with too much stress, issues such as increased abdominal fat and suboptimal
thyroid function occurs.
A new solution to help reduce adrenal fatigue caused by stress and help support healthy cortisol
levels:
Transitions ACTS Adrenal, Cortisol, Thyroid and Stress Support Formula
Primary Benefits of Transitions(tm) ACTS Adrenal, Cortisol, Thyroid and Stress Support
Formula:
* Breaks the chain between stress and weight gain
* Helps balance hormones affected by stress to promote optimal weight
loss
* Helps body adapt to stress
* May help reduce the adrenal fatigue caused by stress
* May help to minimize certain stress related issues (weight gain,
difficulty sleeping, etc.)
* Helps to reduce stress placed on the adrenals to perform, thereby
helping to decrease the possibility of adrenal fatigue
* May help to support normal hypothalamic-pituitary adrenal (HPA)
functions
* May help support stress-related adrenal functions
* Helps to promote healthy levels of cortisol
* Helps maintain healthy levels of both serotonin and dopamine
* Helps enhance and stabilize mood
* Helps to stabilize emotional responses to stress
* May help to maintain normal thyroid function
Key Ingredients Found in Transitions(tm) ACTS Adrenal, Cortisol, Thyroid and Stress Support
Formula:

2. Sensoril® Trim/Ashwagandha root extract: 450 mg
Ashwagandha has antioxidant and sedative properties. It has been proven to act as an adaptogen
by helping to inhibit occasional fatigue, boost energy, promote emotional well-being and
counteract the negative effects of stress.
Preliminary evidence suggests ashwagandha helps to regulate stress-induced levels of dopamine
receptors in the corpus striatum of the brain. It also appears to promote normal levels of plasma
corticosterone, blood urea nitrogen and blood lactic acid. Acting as an adaptogen, ashwagandha
reduces stress placed on adrenals to perform, thereby helping to decrease the possibility of
adrenal fatigue. Though the exact mechanisms by which ashwagandha works are unknown, one
hypothesis is that it functions by way of GABA-mimetic activity which acts independently of
GABA receptors. In addition to its adaptogenic properties, ashwagandha may promote normal
regulation of thyroid function. It has been shown to promote healthy serum levels of the thyroid
hormones triodothyronine (T3) and thyroxine (T4), both
of which are important in promoting normal metabolism.
Holy Basil: 375 mg
Holy basil has adaptogenic and calming activities. Research shows holy basil may help to
promote normal plasma corticosterone levels and hepatic and renal functions, help maintain
normal blood glucose levels, and inhibit several other stress related issues. Though the exact
mechanism of action is not known, it is believed that much of holy basil's effect on stress comes
from its high content of eugenol, caryophyllene and triterpenoic acids, such as ursolic and
oleanolic acids. Studies have shown eugenol to be effective at promoting normal cyclooxygenase
2 (COX 2), an enzyme involved with the inflammatory response.
L-Theanine: 200 mg
L-Theanine is an amino acid found in green tea and some mushrooms.
Preliminary evidence suggests that l-theanine might induce subjective feelings of tranquility in
healthy people. It is believed that l-theanine may work by promoting normal levels of the
neurotransmitters GABA (Gamma Amino Butyric Acid) and dopamine in the central nervous
system. GABA is the primary inhibitory neurotransmitter which promotes calimg effects at the
cellular level. Dopamine aids in the regulation of many functions within the brain in regards to
behavior, cognition, sleep, mood, attention and memory, and is often associated with the 'reward'
or 'pleasure' center of the brain.

3. Passion Flower Extract: 200 mg
Passion flower has sedative and relaxation effects. Some studies have pointed to the flavonoids
in passion flower such as apigenin, vitexin and isovitexin as the primary constituents responsible
for its effects. Research suggests apigenin can bind to central benzodiazepine receptors in the
brain, possibly causing relaxation and helping regulate mood without impairing memory or
motor skills.
Bacopin® (Bacopa monniera Leaf): 150 mg
Bacopa monniera, also referred to as brahmi, has a long history of use in Ayurvedic health for
memory enhancement, support of learning and mood enhancement. Constituents of bacopa,
specifically bacosides A and B, have been shown to support learning ability, cognitive
performance and improve mood. Bacopa also contains the flavonoids apigenin and luteolin.
Research suggests apigenin can bind to central benzodiazepine receptors in the brain, possibly
causing relaxation and helping regulate mood without impairing memory or motor skills.
Rhodiola rosea Root Extract: 150 mg
Rhodiola, or roseroot, acts as an antioxidant and adaptogen, promotes relaxation and mental
clarity, and helps to improve mood. Research suggests that salidroside, one of over 30
compounds found in rhodiola, is responsible for its stimulating and adaptogenic effects. Within
the brain, rhodiola appears to influence the level, activity and transport of monoamine
neurotransmitters, such as dopamine, epinephrine and norepinephrine, and serotonin. Rhodiola
has been proposed to promote healthy neurotransmitter levels.
Eleuthero Root (Eleutherococcus senticosus) Extract: 100 mg Research has shown that eleuthero
root, also known as 'Siberian ginseng,'
has antioxidant, adaptogenic, sedative, as well as many other effects. As an adaptogen, it helps
promote the normal regulation of the endocrine system's response to stressors. The active
compounds in eleuthero root, eleutherosides, are believed to stimulate the pituitary-
adrenocortical system allowing for more efficient regulation of the stress response and healthy
levels of cortisol. Other research suggests that it may help to support feelings of well-being,
reduce occasional fatigue, and improve memory and cognitive performance.
What Makes Transitions(tm) ACTS Adrenal, Cortisol, Thyroid and Stress Support Formula
Unique?
Your job demands a lot of your time. Your family demands just as much, if not more. Trips to
the mailbox are greeted by bills. Every day, life is taking its toll on you. Even in seemingly good
times, stress is something we cannot escape; not only does it have a harmful affect on us

4. mentally, but it can also wreck havoc on us physically - including in our waistlines. Break the
chain between weight loss and stress with Transitions ACTS.*
When we are faced with stress, our bodies go into "fight or flight" response and certain hormones
are released by the adrenal gland, hormones that would give the body a burst of energy and
strength. This response used to be beneficial to our ancestors, allowing their bodies to physically
fight or run away when faced with danger. But in today's society, this response acts much
differently, taking place as a result of stressful days at the office or traffic jam on your way
home. The response is supposed to return to normal once the perceived threat is gone, but if the
body is unable to return to normalcy due to increased stress levels, it could have a negative effect
upon the body with symptoms including adrenal fatigue, suppressed thyroid function, an
imbalance in blood sugar levels, and increased abdominal (adipose) fat.*
One of the hormones released during this "fight or flight" response is cortisol, which increases
blood sugar, suppresses the immune system, and aids in fat, protein and carbohydrate
metabolism. Under normal circumstances, cortisol helps restore homeostasis after stress. The
problem is that constant stress leads to a constant state of cortisol production, which stimulates
glucose production. This excess glucose is typically converted into fat, ending up as stored fat.
High cortisol levels can also lead to binge eating. Not only do high cortisol levels make you want
to keep on snacking, but excess cortisol also contributes to storing more belly fat, which is
known to be a bit harder to lose.*
Cortisol levels also have a direct relationship with the thyroid, and they act synergistically with
one another. Cortisol assists the thyroid hormone in working more efficiently, and the correct
amount of cortisol - not too high or too low - supports normal thyroid function. When cortisol
gets too high, triggered by the adrenal glands response to elevated stress, it causes a delayed
response to the thyroid hormone receptors. When this occurs, the hormones arent allowed to
work at optimal levels, leaving you feeling sluggish, leading to a higher chance of stress eating,
and giving up physical activity.*
When youre battling adrenal fatigue, it is difficult to lose weight for several reasons. Not only are
you exhausted and lack the physical energy to exercise the way that you used to, but those
suffering with adrenal fatigue also crave high fat sweets and salty foods, turning to food as a way
to comfort them and aid in assisting their exhausted adrenal glands. The combination of being
sedentary, having no energy, and eating chips and cookies makes it seemingly impossible to lose
weight, but there is hope, and it can be done without worsening your already delicate state of
health, and without feeling famished.*
Transitions ACTS (Adrenal, Cortisol, Thyroid and Stress) Support Formula, specially formulated
with Holy basil and Ashwagandha, works specifically to promote healthy adrenal gland function,
cortisol levels and thyroid function to help control stress levels and minimize weight gain that is
associated with increased stress. Unlike the competitors, Transitions ACTS doesnt just mask the
problem of weight gain - it addresses the root of the problem by helping your body adapt to
stress and assisting you with your weight management goals.*

5. Frequently Asked Questions about Transitions(tm) ACTS Adrenal, Cortisol, Thyroid and Stress
Support Formula:
How should I take this product?
Take two per day. You may take one pill or both pills at the same time depending on your
preference.
What other nutritional supplements could augment the biological effects of this product?
Isotonix® B-Complex and Isotonix® Multivitamin
What are the contraindications for this supplement?
If you are currently taking warfarin (Coumadin), other anti-platelet/anti-coagulant medications,
antihypertensive medications, anti-depressants, anti-anxiety medications or have an ongoing
medical condition, you should consult your health care provider before using this product. If you
have hyperthyroidism, you should not take this product.
Women who are pregnant or nursing should not use this product. This product may decrease the
effects of stimulants and caffeine.
How does it promote relaxation without making you tired?
The Siberian Ginseng and the Ashwaganadha are natural stimulants. They reduce your stress
levels but aren't formulated to make you drowsy. Ginseng acts similar to caffeine, but doesn't
make you jittery and won't deplete your energy.
Can I take Transitions(tm) Adrenal, Cortisol, Thyroid and Stress Support Formula instead of my
prescription?
No. Transitions(tm) Adrenal, Cortisol, Thyroid and Stress Support Formula is not intended to
replace any prescription medication. Transitions(tm) Adrenal, Cortisol, Thyroid and Stress
Support Formula is a natural reliever of sudden stress. It is intended for use during or after
engaging in stressful activities. You should contact your doctor before changing or discontinuing
the use of any prescription medications.*

6. If I am on a prescription for anxiety, is it safe to use Transitions(tm) Adrenal, Cortisol, Thyroid
and Stress Support Formula?
You should consult your doctor before taking any dietary supplement. The ingredients in
Transitions(tm) Adrenal, Cortisol, Thyroid and Stress Support Formula may have side effects, so
make sure to contact your doctor before mixing them.
What is the relationship between Cortisol and the Thyroid?
Cortisol levels have a direct relationship with the thyroid, and they act synergistically with one
another. Cortisol assists the thyroid hormone in working more efficiently. The correct amount of
cortisol - not too high or too low - supports normal thyroid function. When cortisol gets too high,
triggered by the adrenal glands' response to unwanted stress, it causes a delayed or absent
response from the tissues to the thyroid hormone signal.
This absent or delayed response from the tissues causes resistance from the thyroid hormone
receptors. When cortisol gets too high, and this resistance occurs, it requires more hormones to
create the same effect. That's why elevated stress, which elevates cortisol levels, leads to a
sluggish feeling. The hormones aren't allowed to work at optimal levels. Every cell in the body
has receptors for both cortisol and thyroid and nearly every cellular process requires an optimal
functioning thyroid.*
How does Transitions(tm) Adrenal, Cortisol, Thyroid and Stress Support Formula support
weight management?
When our bodies experience stress, we switch into 'fight or flight' mode - our body's response to
perceived threat or danger. As a result, our bodies prepare to be sustained by building up 'energy'
(aka, fat) and strength for the battle. This response used to be beneficial to our ancestors, but now
this response can be triggered in not so appropriate situations and repetitively. Stress can
physically cause us to put on extra weight - and keep it there. Whenever we are under stress, our
bodies release certain hormones by the adrenal gland - adrenalin and cortisol, cortisol being the
primary stress hormone. Cortisol is a potent signal to do two things - increase appetite and store
fat. Increased cortisol in our body tells our brain that we're hungry, while at the same time telling
our fat cells to store and hold onto as much fat as they can. Transitions Adrenal, Cortisol,
Thyroid and Stress Support Formula is a natural dietary supplement designed to help the body
adapt to stress, promoting healthy levels of cortisol while enhancing and stabilizing mood, and
supporting thyroid function.*