Lusedra® (Fospropofol) Presentation

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Lusedra (Fospropofol) is a new sedative-hypnotic agent indicated for monitored anesthesia care during diagnostic or therapeutic procedures. It works by metabolizing into propofol. Standard dosing for induction is 6.5mg/kg by IV bolus, with supplemental doses of 1.6mg/kg as needed to maintain sedation. Common side effects include nausea, vomiting, headache, and hypotension. It provides moderate sedation and has more predictable pharmacokinetics than propofol.

Gesundheit & Medizin

Lusedra ® (Fospropofol) Gustavo Llerena, PharmD Candidate Pharmacy Services Department Memorial Regional Hospital March 31, 2009

Background 5 ,[object Object],[object Object],[object Object],[object Object],[object Object]

Drug Class 3 ,[object Object],[object Object],[object Object],[object Object],[object Object]

Monitored Anesthesia Care (MAC) 1 ,[object Object],[object Object]

Monitored Anesthesia Care (MAC) ,[object Object],[object Object],[object Object],[object Object],[object Object]

Contraindications 3 ,[object Object],[object Object],[object Object]

Mechanism of Action 3 ,[object Object],[object Object],[object Object],[object Object]

Metabolism 2,3 **Highly Protein Bound (98%) to albumin.

Standard Dosing 3 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Modified Dosing 3 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Side Effects 3 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Monitoring 3 ,[object Object],[object Object]

Therapeutic Alternatives 4,5 ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Counseling 3 ,[object Object],[object Object],[object Object],[object Object],[object Object]

Dispensing/Preparation Considerations 3 ,[object Object],[object Object],[object Object]

References ,[object Object],[object Object],[object Object],[object Object],[object Object]

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