1. Engineering: a key knowledge for boosting the
competitiveness of biotechnology-based companies:

2. PRODINTEC – Introduction
Date created:
October 2004. Formed as a private non-profit. Board
composed of private companies in Asturias, University
and Government of the Principality of Asturias.
Location:
Science and Technology Park of Gijón (Asturias)
Delegation in Madrid:
Science and Technology Park of Madrid, PC 28760
Madrid
Tarjet
Enchancing competitiveness of enterprises through the application of technological advances both
their products and their manufacturing
processes and management.

3. The bridge between research & innovation
Tarjet: the market

4. Research
Spain:
- 9º worldwide position
- 3,3% scientific production
Fuente: SCImago, Scopus, ISI, Thomson Reuters

5. Innovation
39º worldwide position
36º in Europe
Fuente: The Global Competitiveness Report 2011–2012
http://www3.weforum.org/docs/WEF_GCR_Report_2011-12.pdf

6. What is the reason?
Who would go?
What steps do I follow?
How I can have functional prototype
pre-series or commercial?
How I can industrialize my idea?

7. Why innovate in Biotechnology?
• Improving the quality of life of individuals and society
Technologies, techniques, tools, equipment, devices, medical and surgical
procedures, information systems, health programs, organization forms for
the prevention, diagnosis, treatment and rehabilitation.
DEMAND AS THE ECONOMY AS TECHNOLOGY
SOCIETY REQUIRED ALLOWS
HEALTH

8. Value chain
Law firm
1. Detect potentially interested +
• From the research to the market 2. Contact potential applicants
3. Negotiations and drafting
transfer agreement
I Return l Return
M
n i a
v ED CD DD c PE P M r
e e k
n n e
Estrategic Conceptual Detailed Product Production Merchandising
ti Definition Design design
s Engeneering t
o e
Producto Concept Specification, Technical Manufacturing
n definition generation assembly Solution and Process definition
drawings, Manufacturing
prototypes drawings
I
VIABILITY,
d INTELECTUAL
PROPERTY RIGHTS
e
a - Companie
- Research group Licensee +
- Spin Off
- Hospital
+
- Tech Based
companies

9. Objetives
• Provide technical support from invention / patent to the market.
• Provide technological muscle for design and manufacturing process to
provide "value" to the contact process, selection and negotiation with a
licensee end.
- "Convince" the licensee of the technical end.
- Checking the operating principle and development prototypes to
assist in this process.
• Cover the gap between the licensee and technical office, production and
commercialization.
- Provide tools that facilitate the industrialization and placing on the
market

10. Applications
IVD:
Kits and diagnostic devices, sensors, microfluidics, etc..
Detection and measurement of biochemical and biological parameters, identification of toxic
substances, drugs, etc..
Biomedical engineering:
Surgical tools, implants, custom designs, accessories, new features, etc..
Food Biotechnology:
Systems for use in situ detection of contaminants or pollutants detection of biological agents.
Biosensors / Equipment / Instruments:
Prototypes (first series, enclosures, laboratory equipment, cells, interfaces, developing
analytical instrumentation, robotics).
Security and Defence:
Devices for the detection of biochemical weapons,
explosives, and drugs, etc..
Biocatalysis/ Bioreactors
Scale-up, Industrialization, bioreactors design
and manufacturing, etc.

11. Predica Model

12. Areas of activities
PRODUCT DESIGN
PRODUCT ENGINEERING
PROCESS ENGINEERING
INSPECTION PROCESSES
MANUFACTURING TECHNOLOGIES
INNOVATION PROCESSES

13. Future

14. Biomedical Models
Patient/Model
Generation 3D Modeling
and CAD
Choice of technology and
manufacturing
Rapid production of 3D models at low cost. Time
reduction interventions, better communication and
decision making, precise adjustment of implant training.
Applications

15. Tools, Implants, orthopedic, …
Need, implementation,
//Know how/Idea
Generation 3D Modeling
and CAD
Choice of technology and
manufacturing

16. Medical Devices, PoC, Biosensors, …
Protocolo
Mechanical design and
generation of CAD
+
Electrical and electronic
design of the device,
reading system, control,
Choice of technology and Test
manufacturing Product

17. Equipment, Instruments, Machinery…
Need / New functionality /
Machinery ad hoc
Mechanical design and
simulation
+
3D modeling and design
of components
+
Electrical and electronic
design of the device, Choice of technology and Test Product
reading system, control, manufacturing
...

18. Case Studies
Complete redesign and manufacture a set of instruments for bone surgery highly
innovative

19. Case Studies
Design and manufacture of a diagnostic device and electrochemical detection.
Objective: miniaturization, microfluidics [capillary electrophoresis chips], portable,
communication USD / Bluetooth.

20. Case Studies
Instrumentatión Rakes
Instrumentation rakes or combs.
- Pressure and temperature
probes
- To manufacture complex parts
- Withstands high temperatures
Manufacture:
- SLS part made ​by Inconel
- Polished finish
- Manufactured in one piece

21. Equipment
EOSINT M-270 EOSINT M-280 EOS FORMIGA P-100 EOS P-395
Machine Fabrication of direct metal laser sintering: Manufacturing Machine direct laser sintering of plastics:
Able to work with steels, stainless steels, cobalt chrome, brass, Able to work with plastics, nylons, etc.. Layered fabrication
titanium, etc.. Layered fabrication technology that can produce technology that can produce finished parts from 3D CAD and
finished parts from 3D CAD and metal powders. Typical polymeric materials. Typical applications: complex geometric parts,
applications: complex geometric parts, tools, molds with machinery parts and small series without making molds, etc..
conformal channels, custom inserts, prosthetic devices, etc..
Aplications

22. Equipment
EDEN 330 multijet OBJECT CONNEX 500
Rapid Prototyping: Rapid Prototyping:
Prototyping PolyJet technology by injection consisting of Prototyping PolyJet technology by injection consisting of
photoresists and later cured by ultraviolet light. Direct photoresists (possibility of use of 2 different polymer resins
connection to CAD and engineering software reverse simultaneously) and later cured by ultraviolet light. Direct
PRODINTEC connection to CAD and engineering software reverse
PRODINTEC
Aplications
Industries
Materials
Case Studies

23. Equipment
MCP 4/04 ZCORP Z510
Vacuum Casting: Rapid prototyping, prototyping based on material by dust
Making pre-series in plastic and metal from a physical part. and its suburbs by colored liquid. Infiltration finish with
cyanoacrylate (getting very hard piece) or epoxy resin (flexible
piece collection).
Aplications
Industries
Case Studies

24. Equipment
Wittmann-Battenfeld
Deckel Maho KERN Evo
Microsystem50
Milling Microinjection machine, Micromilling machining by chip
fully equipped robotic cell for automated that allows the injection of removal in high speed, to obtain
manufacturing via the machining of large plastic parts, metal and ceramic absolute accuracies in the vicinity of
parts (measuring up to several metres), with micro geometries, handling, one micron. Applications in the field
accuracies of tenths of a millimetre and in quality control and automatic of micro and nanotechnologies
materials such as resin, wood, expanded blister packaging clean room.
polystyrene, etc.
We also have a high-speed 5-axis milling Microinjection Micromilling
machine that allows us to produce very high
precision parts with complex geometries in
any material

25. Equipment
CemLab Mecathronics
Electromagnetic Compatibility Laboratory: Performing Mechatronics: Design and development of electronic circuits.
compatibility tests or external devices developed at the Center Instrumentation, control and measurement. Process
for CE marking automation.
PCB prototyping equipment.

26. In short…
1.- Full development of device from companies know how to prototype or
functional first series.
2.- Manufacturing direct piece further tools and functionalities in teams.
3.- Design and manufacture of machinery and devices for analysis, sensors and
biosensors for diagnosis.
4.- Design and manufacture of interfaces, cells supports analysis kits ...
5.- Manufacture of medical model to patient.
6.- Design and manufacture of devices for detection and sampling.
7.- Unlocking the design constraints of traditional manufacturing processes.
8.- Access to new market niches.
9.- Reduce costs in small series.
10.- "Mass customization", batch unit, as ...
EXAMPLES OF APPLICATION
medical implants, orthopedic products, support structures, surgical tools,
diagnostic devices, interfaces, flow cells, envelopes, microarrays ....

27. International Presence
Technology Platforms International Projets
Rapid Manufacturing European
Plaftorm EKA
Prodintec manager is a board
member
European Technology Platform
Manufuture
Platform manufacturing INTERREG
technologies. In his likeness created
the regional platform PRODINTEC ESTIIC RFID4SME
Manufacturias
NANO4M www.nano4m.eu/
MINAM +NANOfutures
Frame Program
Micro and nanofabrication
FP6: Syntex www.syntex.or.at/
platforms
Prodintec Manager is a board FP7: Light-Rolls (coordinador)
member www.light-rolls.eu/
FP7: NANOfutures (CSA)
Prodintec also a member of: Iberian Red RICAI Center for FP7: CIS3D (NMP)
Innovation, Red PYMERA, Europe InterCluster, HISPAROB Spanish
Technology Platform on Robotics and Technical IDESA Consortia

28. Our Team and facilities

29. PRODINTEC
Centro tecnológico para el diseño y la producción industrial
EDIFICIO CENTROS TECNOLÓGICOS
PARQUE CIENTÍFICO Y TECNOLÓGICO
33203 GIJÓN. ASTURIAS
T +34 984 390 060
F +34 984 390 061
www.prodintec.com
DELEGACION EN MADRID
T +31 667 728 947
www.prodintec.com