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Baxter International

1996 Annual Report
OUR   VISION




A     ll of Baxter’s businesses hold leading positions
      in high-growth global markets. Driving this
leadership are talented, dedicated people, all pursuing
the same vision—to be recognized worldwide as
a leader in providing select, innovative health-care
technologies, products and services to improve lives.
PROFILE               OF   THE   CORPORATION                the businesses of Baxter International



      Baxter International Inc., through its subsidiaries, is a global medical-products and
      services company that is a leader in technologies related to the blood and circulatory
      system. The company has market-leading positions in four global businesses:
      biotechnology, cardiovascular medicine, renal therapy and intravenous systems/
      medical products. The company has achieved global leadership by continuously
      improving its scientiïŹc, marketing and manufacturing capabilities while bringing
      innovative technologies to the medical ïŹeld.
                                        BIOTECH                                                                            CARDIOVASCULAR



      Baxter is a leading developer and manufacturer of products and                            Baxter provides products and services to treat late-stage heart and
      therapies used in transfusion medicine. The company provides systems                      vascular disease. The company is a leading manufacturer of tissue
      for collecting, storing and separating blood and its components, and                      heart valves, valve-repair products and cardiac-monitoring products.
      is a pioneer in the development of such lifesaving therapies as                           Baxter also produces embolectomy catheters and other instruments
      clotting factors for people with hemophilia, and immune globulins                         and equipment used in vascular surgery. The company is a leading
      for patients with immune deïŹciencies. On its own, and through                             provider of blood-ïŹltration devices used during bypass surgery, and
      partnerships, it is developing cellular therapies to treat blood                          contract perfusion services. Baxter’s perfusionists operate heart-lung
      diseases, cancer and other disorders. Baxter invests approximately                        bypass machines and other mechanical devices used during surgery.
      $150 million annually in biotechnology research.
                                                                                                Key Events: During 1996, Baxter completed its acquisition of
      Key Events: Baxter’s Biotech business achieved several milestones                         PSICOR, Inc., the nation’s leading provider of contract perfusion
      in 1996, including becoming the ïŹrst company to initiate U.S. Phase III                   services, and several other perfusion-service providers. The company
      clinical trials for HemAssist ℱ (Diaspirin Cross-linked Hemoglobin or                     strengthened its position in minimally invasive surgery with two
                                                                                                moves: an agreement with two preeminent vascular researchers to
      DCLHb), its “blood substitute,” and conducting U.S. Phase II and III
      clinical trials for Sealagenℱ fibrin sealant, a plasma-derived                            develop an innovative, endovascular graft system that has the
                                                                                                potential to change the therapy for repairing abdominal aortic
      surgical “glue” being studied for its ability to stop bleeding in
                                                                                                aneurysms, and an agreement to acquire Research Medical, Inc.,
      surgical wounds and promote healing. The company also acquired
                                                                                                a provider of specialized cannula and cardioplegia products used
      more than 50 percent of Immuno International AG, an international
                                                                                                in open-heart surgery. Baxter’s Novacor ¼ left-ventricular assist
      leader in infectious-disease research and the development of blood
      products, related biologics and vaccines. This acquisition will allow                     system achieved an important milestone in July 1996: a German
      the two companies to leverage their research-and-development                              patient celebrated his two-year anniversary on the system, believed
      efforts, complementary product lines and global presence.                                 to be the longest duration any patient has spent on such a system.




                                                                                                CardioVascular Net Sales
      Biotech Net Sales
                                                                                                (in billions of dollars)
      (in billions of dollars)


                                                                                          2.0
2.0




                                                                                          1.0
1.0




                                                                                            0
 0
                                                                                                   94      95     96
          94       95       96
PROFILE               OF   THE   CORPORATION              the businesses of Baxter International



      Baxter International Inc., through its subsidiaries, is a global medical-products and
      services company that is a leader in technologies related to the blood and circulatory
      system. The company has market-leading positions in four global businesses:
      biotechnology, cardiovascular medicine, renal therapy and intravenous systems/
      medical products. The company has achieved global leadership by continuously
      improving its scientiïŹc, marketing and manufacturing capabilities while bringing
      innovative technologies to the medical ïŹeld.
                                        RENAL                                                                        I.V. SYSTEMS / MEDICAL PRODUCTS



      Baxter is a leading provider of lifesaving products and services for                    Baxter is well-known for its intravenous (IV) products used in hospitals
      patients who suffer from chronic kidney failure. The two primary                        and other health-care settings such as home care and nursing
      treatments for kidney failure are dialysis and transplantation, and                     homes, but the company’s I.V. Systems/Medical Products business
      Baxter continues to innovate in both areas. Baxter provides products                    also manufactures a range of products for pain management,
      for both hemodialysis, which is administered within a hospital or                       ambulatory infusion and automated prescription-ïŹlling systems.
      clinic, and for peritoneal dialysis (PD), which can be administered                     It also distributes other medical products outside the United States.
      anywhere. Because patients can resume their normal activities while
      undergoing PD, and because it generally is a lower-cost therapy than                    Key Events: The I.V. Systems/Medical Products business has
      hemodialysis, PD is the fastest-growing form of dialysis therapy,                       experienced strong growth in Asia and South America, and has estab-
      particularly outside the United States.                                                 lished joint ventures and alliances to market, or to manufacture and
                                                                                              market IV products and services in such countries as Argentina,
      Key Events: Baxter’s Renal business has expanded in recent years                        Chile, Hungary, Indonesia, the Philippines, Taiwan, Thailand and
      with the opening of several manufacturing facilities and Renal                          Turkey. Last year, Baxter began to establish alliances through
      Therapy Service centers in Asia, Latin America and Europe. Closer to                    which it will construct two new manufacturing facilities in China that
      home, Baxter unveiled Renal Management Strategies Inc., a renal-                        will produce IV solutions and other Baxter products. Baxter’s I.V.
      disease management organization dedicated to creating renal-care                        Systems business is the cornerstone of a seven-year, multi-billion-
      networks across the United States that focus on improving the quality                   dollar purchasing agreement with Premier, the largest alliance
      and reducing the cost of long-term renal care. Meanwhile, Baxter’s                      of hospital and health systems in the United States. During the
      Nextran unit continues its research-and-development efforts in                          year, Baxter reintegrated its parenteral-nutrition business into
      xenotransplantation—animal-to-human transplants—to offer a                              I.V. Systems. That business had been part of Clintec Nutrition
      potential solution to thousands of patients who die each year                           Company, the company’s former joint venture with NestlĂ© S.A.
      awaiting donor organs.                                                                  that was dissolved in 1996.




      Renal Net Sales                                                                         I.V. Systems/Medical Products Net Sales
      (in billions of dollars)                                                                (in billions of dollars)


                                                                                        2.0
2.0




                                                                                        1.0
1.0




                                                                                          0
 0
                                                                                                 94     95      96
          94       95       96
FINANCIAL                     HIGHLIGHTS




                                                                                                          1996                                 1995
                                                         (Dollars in millions, except per share data)

                                                         Net sales                                      $ 5,438                            $ 5,048
      OPERATING RESULTS
                                                         Income from continuing operations
                                                              before income taxes                       $ 793                              $ 524
                                                         Income from continuing operations              $ 575                              $ 371
                                                         Net income                                     $ 669                              $ 649
                                                         Earnings per common share
                                                                   Continuing operations                $ 2.11                             $ 1.34
                                                                   Net income                           $ 2.46                             $ 2.35
                                                         “Operational cash ïŹ‚ow”                         $ 682                              $ 587
                                                         Capital expenditures                           $ 398                              $ 399
      INVESTMENTS
                                                         Research-and-development expenses              $ 340                              $ 345
                                                         Return on common equity           1
                                                                                                          24.3%                                18.5%
      RETURNS
                                                         Dividends per common share                     $ 1.17                             $ 1.11
                                                         Total assets      1
                                                                                                        $ 7,596                            $ 6,818
      OTHER
                                                         Net-debt-to-net-capital ratio                     33.8%                                36.3%
                                                         Stockholders’ equity                           $ 2,504                            $ 3,704
                                                         Common stockholders of record at year-end      65,400                              74,400

      See ïŹnancial section for more information.
      1. Excludes discontinued operations.




      Net Sales                                          Operational Cash Flow
                                                                                                           CONTENTS
      (in billions of dollars)                           (in billions of dollars)

6.0                                                1.0

                                                                                                           Letter to Shareholders                                      2
4.0

                                                   0.5
                                                                                                           One Baxter                                                  4
2.0


 0                                                  0                                                      Biotech                                                     6
          94        95           96                          94       95       96



                                                                                                           CardioVascular                                              8


                                                                                                           Renal                                                       10

                                                         Baxter Stock Price
      Earnings Per Share
                                                         (in dollars)
      from Continuing Operations
                                                                                                           I.V. Systems/Medical Products                               12
      (in dollars)
                                                   45
3.0

                                                                                                           Community Leadership                                        14
                                                   30
2.0


                                                                                                           Financial Information Index                                 16
                                                   15
1.0


                                                    0
 0
                                                             94       95       96
          94        95           96
                                                                                                                                                                       1
                                                                                                           B A X T E R I N T E R N A T I O N A L 1996 annual repor t
LETTER                TO       SHAREHOLDERS                        a message from the Chairman and Chief Executive OfïŹcer




                                                                  Nineteen ninety-six was a year of tremendous accomplishment.
                                                                  We continued to create signiïŹcant shareholder value. We enhanced
                                                                  our leading-edge technologies. We built on our preeminent positions
                                                                  in high-growth medical markets worldwide. And, we spun off our
                                                                  health-care cost management and distribution operations as a
                                                                  separate, publicly traded company called Allegiance Corporation.
                                                                  As a result, Baxter is focused on executing its strategies of global
                                                                  expansion and technological innovation, which we believe will
    Chairman and Chief Executive OfïŹcer,
                                                                  continue to drive signiïŹcant shareholder value in 1997 and beyond.
    Vernon R. Loucks Jr.




    B               axter today is a reinvigorated company, backed by a legacy of leadership more than six decades in the making. While the historic spin-off
                    of Allegiance may have been the “headline,” there were many important achievements in 1996. These include Baxter’s clear leadership in
                    the drive to market a successful hemoglobin therapeutic, or “blood substitute;” our acquisition of Immuno International AG, a top European
    provider of products and services for transfusion medicine; and ongoing growth in attractive markets from Argentina to China.


    OUR FINANCIAL COMMITMENTS Most important of all, in 1996 Baxter kept its commitment to shareholders by meeting or exceeding our aggressive
    ïŹnancial targets. For several years we have set and delivered to speciïŹc, and ambitious, targets designed to generate growth and improve return
    and cash ïŹ‚ow to increase consistently the value of your investment. For 1996, our ïŹnancial targets were to:


                     s Generate        $500 million in “operational cash ïŹ‚ow,” deïŹned as total cash ïŹ‚ow less working capital and capital
                        expenditures. We generated more than $680 million in operational cash ïŹ‚ow.
                     s Grow      net earnings in the high single digits, which we accomplished.
                     s Target      a net-debt-to-capital ratio between 35 percent and 40 percent. This ratio, which was 50 percent at
                        year-end 1993, was reduced to 34 percent by year-end 1996.
                     s Continue        to leverage marketing-and-administrative expenses. These costs have fallen from 21.5 percent
                        of sales in 1995 to 21 percent of sales in 1996.
                     s Double       inventory turns by 1998, using 1993 as a base. While we made signiïŹcant progress toward this
                        goal in 1996, we still have substantial work to do.
                     s Continue        to repurchase an additional $500 million in common stock during the next few years.
                        We are on track to meet this commitment, having repurchased $267 million of shares in 1996.


    Of course, the ïŹnancial measure that matters most is total shareholder return (stock price plus dividend), which rose 14 percent during 1996. It was
    your company’s 40th consecutive annual dividend increase. Over the last three years, total shareholder return has increased at a compound annual
    growth rate of 28 percent—higher than the Dow Jones Industrial Average and the S&P 500. This performance was, however, slightly below the
    S&P Medical Products and Supplies Index. Therefore, management’s bonuses, which are tied directly to the performance of Baxter’s total return
    in relation to this index, were not paid out in full.




2     B A X T E R I N T E R N A T I O N A L 1996 annual repor t
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baxter international 96ar_t

  • 2. OUR VISION A ll of Baxter’s businesses hold leading positions in high-growth global markets. Driving this leadership are talented, dedicated people, all pursuing the same vision—to be recognized worldwide as a leader in providing select, innovative health-care technologies, products and services to improve lives.
  • 3. PROFILE OF THE CORPORATION the businesses of Baxter International Baxter International Inc., through its subsidiaries, is a global medical-products and services company that is a leader in technologies related to the blood and circulatory system. The company has market-leading positions in four global businesses: biotechnology, cardiovascular medicine, renal therapy and intravenous systems/ medical products. The company has achieved global leadership by continuously improving its scientiïŹc, marketing and manufacturing capabilities while bringing innovative technologies to the medical ïŹeld. BIOTECH CARDIOVASCULAR Baxter is a leading developer and manufacturer of products and Baxter provides products and services to treat late-stage heart and therapies used in transfusion medicine. The company provides systems vascular disease. The company is a leading manufacturer of tissue for collecting, storing and separating blood and its components, and heart valves, valve-repair products and cardiac-monitoring products. is a pioneer in the development of such lifesaving therapies as Baxter also produces embolectomy catheters and other instruments clotting factors for people with hemophilia, and immune globulins and equipment used in vascular surgery. The company is a leading for patients with immune deïŹciencies. On its own, and through provider of blood-ïŹltration devices used during bypass surgery, and partnerships, it is developing cellular therapies to treat blood contract perfusion services. Baxter’s perfusionists operate heart-lung diseases, cancer and other disorders. Baxter invests approximately bypass machines and other mechanical devices used during surgery. $150 million annually in biotechnology research. Key Events: During 1996, Baxter completed its acquisition of Key Events: Baxter’s Biotech business achieved several milestones PSICOR, Inc., the nation’s leading provider of contract perfusion in 1996, including becoming the ïŹrst company to initiate U.S. Phase III services, and several other perfusion-service providers. The company clinical trials for HemAssist ℱ (Diaspirin Cross-linked Hemoglobin or strengthened its position in minimally invasive surgery with two moves: an agreement with two preeminent vascular researchers to DCLHb), its “blood substitute,” and conducting U.S. Phase II and III clinical trials for Sealagenℱ fibrin sealant, a plasma-derived develop an innovative, endovascular graft system that has the potential to change the therapy for repairing abdominal aortic surgical “glue” being studied for its ability to stop bleeding in aneurysms, and an agreement to acquire Research Medical, Inc., surgical wounds and promote healing. The company also acquired a provider of specialized cannula and cardioplegia products used more than 50 percent of Immuno International AG, an international in open-heart surgery. Baxter’s Novacor Âź left-ventricular assist leader in infectious-disease research and the development of blood products, related biologics and vaccines. This acquisition will allow system achieved an important milestone in July 1996: a German the two companies to leverage their research-and-development patient celebrated his two-year anniversary on the system, believed efforts, complementary product lines and global presence. to be the longest duration any patient has spent on such a system. CardioVascular Net Sales Biotech Net Sales (in billions of dollars) (in billions of dollars) 2.0 2.0 1.0 1.0 0 0 94 95 96 94 95 96
  • 4. PROFILE OF THE CORPORATION the businesses of Baxter International Baxter International Inc., through its subsidiaries, is a global medical-products and services company that is a leader in technologies related to the blood and circulatory system. The company has market-leading positions in four global businesses: biotechnology, cardiovascular medicine, renal therapy and intravenous systems/ medical products. The company has achieved global leadership by continuously improving its scientiïŹc, marketing and manufacturing capabilities while bringing innovative technologies to the medical ïŹeld. RENAL I.V. SYSTEMS / MEDICAL PRODUCTS Baxter is a leading provider of lifesaving products and services for Baxter is well-known for its intravenous (IV) products used in hospitals patients who suffer from chronic kidney failure. The two primary and other health-care settings such as home care and nursing treatments for kidney failure are dialysis and transplantation, and homes, but the company’s I.V. Systems/Medical Products business Baxter continues to innovate in both areas. Baxter provides products also manufactures a range of products for pain management, for both hemodialysis, which is administered within a hospital or ambulatory infusion and automated prescription-ïŹlling systems. clinic, and for peritoneal dialysis (PD), which can be administered It also distributes other medical products outside the United States. anywhere. Because patients can resume their normal activities while undergoing PD, and because it generally is a lower-cost therapy than Key Events: The I.V. Systems/Medical Products business has hemodialysis, PD is the fastest-growing form of dialysis therapy, experienced strong growth in Asia and South America, and has estab- particularly outside the United States. lished joint ventures and alliances to market, or to manufacture and market IV products and services in such countries as Argentina, Key Events: Baxter’s Renal business has expanded in recent years Chile, Hungary, Indonesia, the Philippines, Taiwan, Thailand and with the opening of several manufacturing facilities and Renal Turkey. Last year, Baxter began to establish alliances through Therapy Service centers in Asia, Latin America and Europe. Closer to which it will construct two new manufacturing facilities in China that home, Baxter unveiled Renal Management Strategies Inc., a renal- will produce IV solutions and other Baxter products. Baxter’s I.V. disease management organization dedicated to creating renal-care Systems business is the cornerstone of a seven-year, multi-billion- networks across the United States that focus on improving the quality dollar purchasing agreement with Premier, the largest alliance and reducing the cost of long-term renal care. Meanwhile, Baxter’s of hospital and health systems in the United States. During the Nextran unit continues its research-and-development efforts in year, Baxter reintegrated its parenteral-nutrition business into xenotransplantation—animal-to-human transplants—to offer a I.V. Systems. That business had been part of Clintec Nutrition potential solution to thousands of patients who die each year Company, the company’s former joint venture with NestlĂ© S.A. awaiting donor organs. that was dissolved in 1996. Renal Net Sales I.V. Systems/Medical Products Net Sales (in billions of dollars) (in billions of dollars) 2.0 2.0 1.0 1.0 0 0 94 95 96 94 95 96
  • 5. FINANCIAL HIGHLIGHTS 1996 1995 (Dollars in millions, except per share data) Net sales $ 5,438 $ 5,048 OPERATING RESULTS Income from continuing operations before income taxes $ 793 $ 524 Income from continuing operations $ 575 $ 371 Net income $ 669 $ 649 Earnings per common share Continuing operations $ 2.11 $ 1.34 Net income $ 2.46 $ 2.35 “Operational cash ïŹ‚ow” $ 682 $ 587 Capital expenditures $ 398 $ 399 INVESTMENTS Research-and-development expenses $ 340 $ 345 Return on common equity 1 24.3% 18.5% RETURNS Dividends per common share $ 1.17 $ 1.11 Total assets 1 $ 7,596 $ 6,818 OTHER Net-debt-to-net-capital ratio 33.8% 36.3% Stockholders’ equity $ 2,504 $ 3,704 Common stockholders of record at year-end 65,400 74,400 See ïŹnancial section for more information. 1. Excludes discontinued operations. Net Sales Operational Cash Flow CONTENTS (in billions of dollars) (in billions of dollars) 6.0 1.0 Letter to Shareholders 2 4.0 0.5 One Baxter 4 2.0 0 0 Biotech 6 94 95 96 94 95 96 CardioVascular 8 Renal 10 Baxter Stock Price Earnings Per Share (in dollars) from Continuing Operations I.V. Systems/Medical Products 12 (in dollars) 45 3.0 Community Leadership 14 30 2.0 Financial Information Index 16 15 1.0 0 0 94 95 96 94 95 96 1 B A X T E R I N T E R N A T I O N A L 1996 annual repor t
  • 6. LETTER TO SHAREHOLDERS a message from the Chairman and Chief Executive OfïŹcer Nineteen ninety-six was a year of tremendous accomplishment. We continued to create signiïŹcant shareholder value. We enhanced our leading-edge technologies. We built on our preeminent positions in high-growth medical markets worldwide. And, we spun off our health-care cost management and distribution operations as a separate, publicly traded company called Allegiance Corporation. As a result, Baxter is focused on executing its strategies of global expansion and technological innovation, which we believe will Chairman and Chief Executive OfïŹcer, continue to drive signiïŹcant shareholder value in 1997 and beyond. Vernon R. Loucks Jr. B axter today is a reinvigorated company, backed by a legacy of leadership more than six decades in the making. While the historic spin-off of Allegiance may have been the “headline,” there were many important achievements in 1996. These include Baxter’s clear leadership in the drive to market a successful hemoglobin therapeutic, or “blood substitute;” our acquisition of Immuno International AG, a top European provider of products and services for transfusion medicine; and ongoing growth in attractive markets from Argentina to China. OUR FINANCIAL COMMITMENTS Most important of all, in 1996 Baxter kept its commitment to shareholders by meeting or exceeding our aggressive ïŹnancial targets. For several years we have set and delivered to speciïŹc, and ambitious, targets designed to generate growth and improve return and cash ïŹ‚ow to increase consistently the value of your investment. For 1996, our ïŹnancial targets were to: s Generate $500 million in “operational cash ïŹ‚ow,” deïŹned as total cash ïŹ‚ow less working capital and capital expenditures. We generated more than $680 million in operational cash ïŹ‚ow. s Grow net earnings in the high single digits, which we accomplished. s Target a net-debt-to-capital ratio between 35 percent and 40 percent. This ratio, which was 50 percent at year-end 1993, was reduced to 34 percent by year-end 1996. s Continue to leverage marketing-and-administrative expenses. These costs have fallen from 21.5 percent of sales in 1995 to 21 percent of sales in 1996. s Double inventory turns by 1998, using 1993 as a base. While we made signiïŹcant progress toward this goal in 1996, we still have substantial work to do. s Continue to repurchase an additional $500 million in common stock during the next few years. We are on track to meet this commitment, having repurchased $267 million of shares in 1996. Of course, the ïŹnancial measure that matters most is total shareholder return (stock price plus dividend), which rose 14 percent during 1996. It was your company’s 40th consecutive annual dividend increase. Over the last three years, total shareholder return has increased at a compound annual growth rate of 28 percent—higher than the Dow Jones Industrial Average and the S&P 500. This performance was, however, slightly below the S&P Medical Products and Supplies Index. Therefore, management’s bonuses, which are tied directly to the performance of Baxter’s total return in relation to this index, were not paid out in full. 2 B A X T E R I N T E R N A T I O N A L 1996 annual repor t