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Bear Stearns Global Healthcare
         Conference
       September 14, 2004
John H. Hammergren,
                Chairman and
            Chief Executive Officer




9/14/2004                     1
Safe Harbor Clause
   Some of the information in this presentation may
   constitute forward-looking statements that are
   subject to various uncertainties.
   These uncertainties could cause actual results to
   differ materially from those projected or implied.
   The risk factors associated with those uncertainties
   are described in the Company’s reports and
   exhibits filed with the Securities and Exchange
   Commission.




9/14/2004                               2
Overview


     Who We Are


     Our View of Healthcare


     How Our Businesses Are Responding to
     Current Challenges




9/14/2004                        3
Who We Are




9/14/2004                4
McKesson’s Solutions …
  Building on Distribution Strength


                                          Solutions for
                                        medication safety
  Pharmaceutical & medical-
surgical distribution to all sites
                                                                           Clinical, financial &
                                                                         resource management
                                                                          for hospitals & IDNs




                          Inpatient automation
                                                          Specialty
Retail pharmacy                                        pharmaceuticals
  automation

                                                                                 Disease
                                                                               management

                   Drug cards for          Pharmaceutical
                      seniors               repackaging
   9/14/2004                                                    5
Our Business Today



                                                             McKesson
                                  McKesson
              McKesson
                                                        Provider Technologies
                                Medical-
                                Medical-Surgical
            Pharmaceutical
                                                        63% of health systems
                               #1 in primary care
    #1 in U.S., Canada, and
             Mexico
                                                        51% of hospitals with
                                #1 in extended
                                                            200+ beds
                                      care
      Large Rx repackaging
                                                         Leader in clinical,
                                  Total supply
   Leading generics provider
                                                           revenue cycle,
                                solution in acute
      #1 in retail pharmacy                                 and resource
                                       care
           automation                                   management solutions
                                 Private label
    Specialty distribution &                             More “Best in KLAS”
                               product offerings
      patient services for                                products than any
                                Rapid growth in
        manufacturers                                       other vendor
                                physician office
 #1 in medical management                                #1 in robotic hospital
                                pharmaceuticals
  software and services for                              pharmacy dispensing
                                 and equipment
           payors
                                                        #1 in bedside scanning
 #1 in disease management
    for Medicaid agencies
9/14/2004                                           6
Strong, Long-term Customer
Relationships with Market Leaders
             Vanderbilt University Medical Center




 9/14/2004                                     7
FY05 Q1 Consolidated Financial
          Results
                                      Q1 Results
  ($ in millions, except EPS)
                                    FY04      FY05

  Revenues                      $ 16,524     $ 19,187    16%


  Gross Profit                         787         852   8%
                                     4.76%       4.44%
    Gross Profit Margin                                  (32) bp


  Operating Income                     252         261   4%
    Operating Income Margin          1.52%       1.36%   (16) bp


  Net Income                    $     156    $    164    5%


  Diluted EPS                   $     0.53   $    0.55   4%


  Weighted Average Shares             298         300



9/14/2004                               8
Our View of Healthcare




9/14/2004                    9
Trends Driving Healthcare
                   Growth
                   Reduce medical errors                                Payors taking on more risk
                   Adopt clinical protocols/                            Limitations on use of
                                                  Increased
                   evidence-based medicine                              managed care tools
  Focus on
                                                 pressure on            Employer pressures on
Quality of Care                                     payors              double-digit premium
                                                                        increases



                   Chronic disease                                      Automation to overcome
                                                    Continued
                   management                                           labor shortages
                                                improvements in
 Outpatient and    Case management                                      Electronic claims and
chronic disease                                  operational and
                   Manage high-cost diseases                            eligibility
  management                                      administrative
                   in small populations                                 Online prescription and lab
                                                    efficiency          transmissions
                                                                        Streamlined pre-authorization


                   Biotech pipeline expansion                           Unhappy consumers
                   New drug delivery                                    Better informed consumers
Continued use      mechanisms
 of new drugs,                                    Increased
                   Rapid growth in generics
 but increased                                   consumerism
                   Regulatory pressures on
pricing scrutiny
                   pricing



  9/14/2004                                                        10
Improved U.S. Healthcare
                    by 2010
            Informed clinical
             Informed clinical
                 practice
                  practice

                                      CULTURE
                                      CULTURE
            Interconnection
             Interconnection
                                       CHANGE
                                       CHANGE

            Improved safety
            Improved safety             in the
                                        in the
             and efficiency
             and efficiency
                                      delivery of
                                      delivery of

            Personalized care         healthcare
                                      healthcare
            Personalized care


            Population health
            Population health
               initiatives
                initiatives
9/14/2004                        11
McKesson’s Strategy
 To bring together clinical knowledge, process
   expertise, technology, and the resources of
     a Fortune 16 company to fundamentally
        change the cost and quality of healthcare.

 Create long-term                                Introduce
relationships based    Sell McKesson’s        innovations that
on custom solutions     comprehensive         address emerging
    that deliver            offering             healthcare
   ROI & quality                                 challenges




 9/14/2004                               12
How Our Businesses
            Are Responding to Current
                   Challenges




9/14/2004                     13
Pharmaceutical Solutions




9/14/2004                    14
FY05 Q1 Financial Results –
         Pharmaceutical Solutions
                                                  Q1 Results
  ($ in millions)
                                                FY04      FY05
  Revenues
    U.S. direct distribution & services     $    9,335   $ 11,011   18%
    U.S. sales to customer warehouses            5,164      5,916   15%
          Subtotal                              14,499     16,928   17%
    Canada distribution & services               1,044      1,252   20%
          T otal Pharmaceutical Solutions       15,543     18,180   17%


  Gross Profit                                     518       560    8%
    Gross Profit Margin                          3.33%     3.08%    (25) bp


  Operating Profit                                 265       291    10%
    Operating Profit Margin                      1.70%     1.60%    (10) bp




9/14/2004                                           15
Pharmaceutical Solutions
                  Highlights
     Above market revenue growth of 17%
            VA implementation successful with annualized
            revenues in excess of $3.5B, better profitability
            AdvancePCS volume of Caremark awarded to
            McKesson with annualized revenues of $2B
     Continued strong growth in Canada
     Expansion of generics business
     IT/Operations Plan completed - operating
     efficiencies are being realized



9/14/2004                                     16
U.S. Pharmaceutical Distribution
         Environment
     Evolution in manufacturer economics
            Historical economics based solely on
            pharmaceutical price inflation
            Changes underway in healthcare may impact
            pharmaceutical pricing
            Transition toward fee-based compensation for
            services proceeding slowly
     Customer pricing model established on inflation-
     based profit opportunities




9/14/2004                                  17
Progress with Manufacturer
              Economics
 Collaborative strategy designed to deliver more
 predictable core distribution fees based on value
 provided
        Appropriate compensation being received from smaller
        branded and generics suppliers that were sent letters
        implementing fee-for-service
        New agreements completed with more than 50% of
        larger pharmaceutical manufacturers
        Compensation from largest manufacturers still tied to
        the timing and magnitude of price increases
 Fee-for-service agreements completed with large
 manufacturers by March 31, 2005 fiscal year end


9/14/2004                                   18
Fewer Q2 Price Increases Will
Reduce Pharma Solutions Earnings
      Significant portion of operating profit dependent
      on price increases
      Plan assumed pattern and magnitude of price
      increases consistent with history
      While magnitude is consistent, price increases
      weighted by volume down significantly
      Assumption that remaining price increases will
      still be realized
      VA upside and new AdvancePCS volume help
      close the gap

 9/14/2004                             19
Improve Existing Customer
                   Profitability
 Improving compliance and efficiency across
 customer base
        Eliminate non-prime vendor customers
        Enforce contract terms (e.g., generic compliance)
        Charge for additional services (e.g. emergency
        shipments, minimum order size, etc.)
 Focus on securing prime vendor relationships
 exclusively
        Eliminate customers that do not adhere, reduce
        secondary relationships


9/14/2004                                 20
Medical-Surgical Solutions




9/14/2004                      21
FY05 Q1 Financial Results –
        Medical-Surgical Solutions
                                    Q1 Results
  ($ in millions)
                                  FY04      FY05

  Revenues                    $      710   $     707    0%


  Gross Profit                       146          159   9%
                                  20.56%       22.44%
    Gross Profit Margin                                 188   bp



  Operating Profit                    26           29   11%
    Operating Profit Margin        3.63%        4.04%    41   bp




9/14/2004                             22
Medical-Surgical Solutions
                    Highlights
 Operating improvement plan continues to deliver
 positive results
 6 consecutive quarters of year-over-year increased
 operating profit and operating margin rate
        Operating profit growth of 11% in 1st quarter
 Strong Q1 revenue growth of 22% in alternate site
 driven by new products and vaccine sales
 New Optyx analytical service creates opportunity
 for differentiation in acute care



9/14/2004                                  23
McKesson Provider
              Technologies




9/14/2004                 24
FY05 Q1 Financial Results –
          Provider Technologies
                                              Q1 Results
  ($ in millions)
                                            FY04      FY05
  Revenues
    Software & software systems         $       46   $      51    11%
    Services                                   204         222    9%
    Hardware                                    21          27    29%
         T otal Provider Technologies   $      271   $     300    11%


  Gross Profit                                 122          133   9%
    Gross Profit Margin                     45.18%       44.34%   (84) bp


  Operating Profit                               5           14 204%
    Operating Profit Margin                  1.74%        4.77% 303     bp




9/14/2004                                       25
Provider Technologies
                  Highlights
     Q1 revenue growth of 11% reflects continued
     strong demand for clinical solutions
     Demand for revenue cycle and resource
     management solutions remains flat
     Government focus on HIT may drive future
     growth opportunities
     New solutions being introduced to enhance the
     patient experience and bedside safety
     Reorganization should improve product
     integration and selling effectiveness under one
     McKesson strategy


9/14/2004                             26
Summary




9/14/2004             27
What McKesson Represents
Core pharmaceutical business positioned for growth
with a strategy in place to address industry
evolution
Stable of additional businesses poised to take
advantage of new opportunities in healthcare
Track record of financial performance
       Consistent annual EPS growth despite challenges
       Increasing cash flow
       Strong balance sheet provides financial flexibility
       Commitment to financial transparency


9/14/2004                                  28
Outlook

FY05 expectation: $2.20 to $2.35 per share
       First half down, stronger growth in second half
       based on resumption of price increases
Long Term:
       Grow revenues at or above 10% per year
       Achieve EPS growth in the mid-teens once the
       changes in business are completed
       Continue to improve ROCC


      Create Value for Suppliers, Customers and
                    Shareholders
9/14/2004                              29
9/14/2004   30

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Bear Stearns 17th Annual Healthcare Conference

  • 1. Bear Stearns Global Healthcare Conference September 14, 2004
  • 2. John H. Hammergren, Chairman and Chief Executive Officer 9/14/2004 1
  • 3. Safe Harbor Clause Some of the information in this presentation may constitute forward-looking statements that are subject to various uncertainties. These uncertainties could cause actual results to differ materially from those projected or implied. The risk factors associated with those uncertainties are described in the Company’s reports and exhibits filed with the Securities and Exchange Commission. 9/14/2004 2
  • 4. Overview Who We Are Our View of Healthcare How Our Businesses Are Responding to Current Challenges 9/14/2004 3
  • 6. McKesson’s Solutions … Building on Distribution Strength Solutions for medication safety Pharmaceutical & medical- surgical distribution to all sites Clinical, financial & resource management for hospitals & IDNs Inpatient automation Specialty Retail pharmacy pharmaceuticals automation Disease management Drug cards for Pharmaceutical seniors repackaging 9/14/2004 5
  • 7. Our Business Today McKesson McKesson McKesson Provider Technologies Medical- Medical-Surgical Pharmaceutical 63% of health systems #1 in primary care #1 in U.S., Canada, and Mexico 51% of hospitals with #1 in extended 200+ beds care Large Rx repackaging Leader in clinical, Total supply Leading generics provider revenue cycle, solution in acute #1 in retail pharmacy and resource care automation management solutions Private label Specialty distribution & More “Best in KLAS” product offerings patient services for products than any Rapid growth in manufacturers other vendor physician office #1 in medical management #1 in robotic hospital pharmaceuticals software and services for pharmacy dispensing and equipment payors #1 in bedside scanning #1 in disease management for Medicaid agencies 9/14/2004 6
  • 8. Strong, Long-term Customer Relationships with Market Leaders Vanderbilt University Medical Center 9/14/2004 7
  • 9. FY05 Q1 Consolidated Financial Results Q1 Results ($ in millions, except EPS) FY04 FY05 Revenues $ 16,524 $ 19,187 16% Gross Profit 787 852 8% 4.76% 4.44% Gross Profit Margin (32) bp Operating Income 252 261 4% Operating Income Margin 1.52% 1.36% (16) bp Net Income $ 156 $ 164 5% Diluted EPS $ 0.53 $ 0.55 4% Weighted Average Shares 298 300 9/14/2004 8
  • 10. Our View of Healthcare 9/14/2004 9
  • 11. Trends Driving Healthcare Growth Reduce medical errors Payors taking on more risk Adopt clinical protocols/ Limitations on use of Increased evidence-based medicine managed care tools Focus on pressure on Employer pressures on Quality of Care payors double-digit premium increases Chronic disease Automation to overcome Continued management labor shortages improvements in Outpatient and Case management Electronic claims and chronic disease operational and Manage high-cost diseases eligibility management administrative in small populations Online prescription and lab efficiency transmissions Streamlined pre-authorization Biotech pipeline expansion Unhappy consumers New drug delivery Better informed consumers Continued use mechanisms of new drugs, Increased Rapid growth in generics but increased consumerism Regulatory pressures on pricing scrutiny pricing 9/14/2004 10
  • 12. Improved U.S. Healthcare by 2010 Informed clinical Informed clinical practice practice CULTURE CULTURE Interconnection Interconnection CHANGE CHANGE Improved safety Improved safety in the in the and efficiency and efficiency delivery of delivery of Personalized care healthcare healthcare Personalized care Population health Population health initiatives initiatives 9/14/2004 11
  • 13. McKesson’s Strategy To bring together clinical knowledge, process expertise, technology, and the resources of a Fortune 16 company to fundamentally change the cost and quality of healthcare. Create long-term Introduce relationships based Sell McKesson’s innovations that on custom solutions comprehensive address emerging that deliver offering healthcare ROI & quality challenges 9/14/2004 12
  • 14. How Our Businesses Are Responding to Current Challenges 9/14/2004 13
  • 16. FY05 Q1 Financial Results – Pharmaceutical Solutions Q1 Results ($ in millions) FY04 FY05 Revenues U.S. direct distribution & services $ 9,335 $ 11,011 18% U.S. sales to customer warehouses 5,164 5,916 15% Subtotal 14,499 16,928 17% Canada distribution & services 1,044 1,252 20% T otal Pharmaceutical Solutions 15,543 18,180 17% Gross Profit 518 560 8% Gross Profit Margin 3.33% 3.08% (25) bp Operating Profit 265 291 10% Operating Profit Margin 1.70% 1.60% (10) bp 9/14/2004 15
  • 17. Pharmaceutical Solutions Highlights Above market revenue growth of 17% VA implementation successful with annualized revenues in excess of $3.5B, better profitability AdvancePCS volume of Caremark awarded to McKesson with annualized revenues of $2B Continued strong growth in Canada Expansion of generics business IT/Operations Plan completed - operating efficiencies are being realized 9/14/2004 16
  • 18. U.S. Pharmaceutical Distribution Environment Evolution in manufacturer economics Historical economics based solely on pharmaceutical price inflation Changes underway in healthcare may impact pharmaceutical pricing Transition toward fee-based compensation for services proceeding slowly Customer pricing model established on inflation- based profit opportunities 9/14/2004 17
  • 19. Progress with Manufacturer Economics Collaborative strategy designed to deliver more predictable core distribution fees based on value provided Appropriate compensation being received from smaller branded and generics suppliers that were sent letters implementing fee-for-service New agreements completed with more than 50% of larger pharmaceutical manufacturers Compensation from largest manufacturers still tied to the timing and magnitude of price increases Fee-for-service agreements completed with large manufacturers by March 31, 2005 fiscal year end 9/14/2004 18
  • 20. Fewer Q2 Price Increases Will Reduce Pharma Solutions Earnings Significant portion of operating profit dependent on price increases Plan assumed pattern and magnitude of price increases consistent with history While magnitude is consistent, price increases weighted by volume down significantly Assumption that remaining price increases will still be realized VA upside and new AdvancePCS volume help close the gap 9/14/2004 19
  • 21. Improve Existing Customer Profitability Improving compliance and efficiency across customer base Eliminate non-prime vendor customers Enforce contract terms (e.g., generic compliance) Charge for additional services (e.g. emergency shipments, minimum order size, etc.) Focus on securing prime vendor relationships exclusively Eliminate customers that do not adhere, reduce secondary relationships 9/14/2004 20
  • 23. FY05 Q1 Financial Results – Medical-Surgical Solutions Q1 Results ($ in millions) FY04 FY05 Revenues $ 710 $ 707 0% Gross Profit 146 159 9% 20.56% 22.44% Gross Profit Margin 188 bp Operating Profit 26 29 11% Operating Profit Margin 3.63% 4.04% 41 bp 9/14/2004 22
  • 24. Medical-Surgical Solutions Highlights Operating improvement plan continues to deliver positive results 6 consecutive quarters of year-over-year increased operating profit and operating margin rate Operating profit growth of 11% in 1st quarter Strong Q1 revenue growth of 22% in alternate site driven by new products and vaccine sales New Optyx analytical service creates opportunity for differentiation in acute care 9/14/2004 23
  • 25. McKesson Provider Technologies 9/14/2004 24
  • 26. FY05 Q1 Financial Results – Provider Technologies Q1 Results ($ in millions) FY04 FY05 Revenues Software & software systems $ 46 $ 51 11% Services 204 222 9% Hardware 21 27 29% T otal Provider Technologies $ 271 $ 300 11% Gross Profit 122 133 9% Gross Profit Margin 45.18% 44.34% (84) bp Operating Profit 5 14 204% Operating Profit Margin 1.74% 4.77% 303 bp 9/14/2004 25
  • 27. Provider Technologies Highlights Q1 revenue growth of 11% reflects continued strong demand for clinical solutions Demand for revenue cycle and resource management solutions remains flat Government focus on HIT may drive future growth opportunities New solutions being introduced to enhance the patient experience and bedside safety Reorganization should improve product integration and selling effectiveness under one McKesson strategy 9/14/2004 26
  • 29. What McKesson Represents Core pharmaceutical business positioned for growth with a strategy in place to address industry evolution Stable of additional businesses poised to take advantage of new opportunities in healthcare Track record of financial performance Consistent annual EPS growth despite challenges Increasing cash flow Strong balance sheet provides financial flexibility Commitment to financial transparency 9/14/2004 28
  • 30. Outlook FY05 expectation: $2.20 to $2.35 per share First half down, stronger growth in second half based on resumption of price increases Long Term: Grow revenues at or above 10% per year Achieve EPS growth in the mid-teens once the changes in business are completed Continue to improve ROCC Create Value for Suppliers, Customers and Shareholders 9/14/2004 29
  • 31. 9/14/2004 30