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Lamberto Andreotti
                                       Executive Vice President
                                                  &
                                        Chief Operating Officer

                       Deutsche Bank Healthcare Conference
                                  May 7, 2008

This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-
May 7, 2008

    During this meeting, we will make statements about the Company’s future
    plans and prospects, including statements about our financial position,
    business strategy, research pipeline concerning product development and
    product potential, that constitute forward-looking statements for purposes
    of the safe harbor provisions under the Private Securities Litigation Reform
    Act of 1995.
    Actual results may differ materially from those indicated by these forward-
    looking statements as a result of various important factors, including those
    discussed in the company’s most recent annual report on Form 10-K,
    periodic reports on Form 10-Q and current reports on Form 8-K. These
    documents are available from the SEC, the Bristol-Myers Squibb website
    or from Bristol-Myers Squibb Investor Relations.
    In addition, any forward-looking statements represent our estimates only as
    of today and should not be relied upon as representing our estimates as of
    any subsequent date. While we may elect to update forward-looking
    statements at some point in the future, we specifically disclaim any
    obligation to do so, even if our estimates change.


This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-
Next Generation BioPharma

                                                                            Best of Pharma
                                      Best of Biotech


                                                    Next Generation
                                                      BioPharma


                                                          Selectively
                   Innovative                                                                          Continuous
                                                          Integrated
                    Portfolio                                                                         Improvement
                                                        Business Model


                     Agile, Entrepreneurial and Accountable Culture

This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                 3
Q1 2008 Performance

                  Strong underlying sales growth +9%
                  Gross and operating margin improvement
                  Non-GAAP EPS of $0.42 vs. $0.36 Q1 2007
                  Decision to retain Mead Johnson within
                  business portfolio
                  Recent announcement to sell ConvaTec
                  Confirmed 3 year non-GAAP guidance

All GAAP to non-GAAP reconciliations are available on our website.
This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                          4
Q1 2008 Sales: Growth Brands
         $1,400
                          $1,308
                           +39%
         $1,200

         $1,000

            $800
  $M
            $600
                                              $454
            $400                              +24%                                   $297
                                                                 $305                                   $273
                                                                                                                $187
                                                                 +13%               +13%               +21%
            $200
                                                                                                               +17%
                $0
                          Plavix             Abilify           Avapro             Reyataz            Sustiva   Erbitux

This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                      5
Q1 2008 Sales: New Products
         $120
                            $108
                           +140%
         $100
                                                          $87
           $80                                         +112%
                                                                                      $66
  $M       $60                                                                      +314%

           $40
                                                                                                              $25
           $20


             $0
                        Baraclude                     Orencia                      Sprycel                   Ixempra

This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                    6
Plavix Indications
                                                                                  Potential Patient
      Proven Efficacy
      and Safety                                                                Population ~49 million
           Indicated for use in broad
           patient population                                                 Other CV
                                                                              ~28 million
           Efficacy and safety of                                                                              ACS / Stent
           Plavix well understood                                                                               ~1.5 million
                                                                                                                ACS
                                                                           PAD       Stroke
           Increased hospital
                                                                                                               ~3 million
                                                                         ~8 million ~10 million
           resources focused
           on risk benefit                                                                                   ACS / Non-Stent
                                                                                                               ~1.5 million
           Growth opportunities
           within ACS as well as
           stroke and PAD


This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                            7
Abilify – Broad Clinical Profile and
      Specialty Execution

                   Q1 global sales up 24%

                   Broadest set of indications for any atypical

                   US approval in major depressive disorder

                   EU approval for bipolar mania

                   Succesful DTC campaign



This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                          8
Orencia – Goal to Become
      the IV Biologic of Choice

                   Q1 sales $87 million +112%
                   Focus on efficacy and durability of response
                   Recent label change broadening indication
                   regardless of prior treatment
                   Promotional programs focused on
                   compliance and persistence
                   DTC campaign focused on defining
                   inadequate response


This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                          9
Our Productivity Approach
                                                    Management Council
                                         Productivity Transformation Team

                     Supply Chain                     R&D                                                    G&A
                                                                          Commercial
                                                                           Operations
                        $400 MM                  $200 MM                  $550 MM                  $350 MM




                                     $1.5 Billion
                            Cost Savings + Cost Avoidance


This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                10
Supply Chain Redesigned to Support
      BioPharma Model
                                                     Strategic Filters
         Current                                                                                                2011
        27 Plants                                                                                            >50% Reduction

                                        Future             Geographic    Product
                                       Portfolio            Footprint Rationalization

                     Network segmented and specialized
                     In-house Biologics capability
                     Aggressive outsourcing of mature products

                   Generating $400 Million in Productivity
This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                       11
Customer Model Restructured
      to Support BioPharma
          12,000
                                                                                                             Primary Care
          10,000
                                                                                                             Specialty
           8,000                                                                                             Field-Based Medical
 FTEs
                                                                                                             Total Field Force
           6,000

           4,000

           2,000

                 0
                             2005                  2006                  2007                  2008
              Specialty Model synergizes Sales Force and Field-Based
              Medical experts
              Partnering on Primary Care maximizes capacity and
              capability while minimizing fixed overhead
              Increasing productivity
This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                            12
Key 2008 Events
                          ASCO
                           – Erbitux FLEX data
                           – Sprycel phase II prostate data
                           – Ipilimumab data
                          ADA
                           – Saxagliptin phase III data
                           – Dapaglifozin phase IIb data
                          EASD
                           – Saxagliptin phase III data
                          ASH
                           – Apixiban phase III data
This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                          13
Next Generation BioPharma

                                                                            Best of Pharma
                                      Best of Biotech


                                                    Next Generation
                                                      BioPharma


                                                          Selectively
                   Innovative                                                                          Continuous
                                                          Integrated
                    Portfolio                                                                         Improvement
                                                        Business Model


                     Agile, Entrepreneurial and Accountable Culture

This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-                                 14
Lamberto Andreotti
                                       Executive Vice President
                                                  &
                                        Chief Operating Officer

                       Deutsche Bank Healthcare Conference
                                  May 7, 2008

This presentation is intended solely for an investment community/industry audience-not for promotional use
                                                       community/industry audience-

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BMS Exec Discusses Q1 Performance, Growth Brands, Pipeline

  • 1. Lamberto Andreotti Executive Vice President & Chief Operating Officer Deutsche Bank Healthcare Conference May 7, 2008 This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience-
  • 2. May 7, 2008 During this meeting, we will make statements about the Company’s future plans and prospects, including statements about our financial position, business strategy, research pipeline concerning product development and product potential, that constitute forward-looking statements for purposes of the safe harbor provisions under the Private Securities Litigation Reform Act of 1995. Actual results may differ materially from those indicated by these forward- looking statements as a result of various important factors, including those discussed in the company’s most recent annual report on Form 10-K, periodic reports on Form 10-Q and current reports on Form 8-K. These documents are available from the SEC, the Bristol-Myers Squibb website or from Bristol-Myers Squibb Investor Relations. In addition, any forward-looking statements represent our estimates only as of today and should not be relied upon as representing our estimates as of any subsequent date. While we may elect to update forward-looking statements at some point in the future, we specifically disclaim any obligation to do so, even if our estimates change. This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience-
  • 3. Next Generation BioPharma Best of Pharma Best of Biotech Next Generation BioPharma Selectively Innovative Continuous Integrated Portfolio Improvement Business Model Agile, Entrepreneurial and Accountable Culture This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 3
  • 4. Q1 2008 Performance Strong underlying sales growth +9% Gross and operating margin improvement Non-GAAP EPS of $0.42 vs. $0.36 Q1 2007 Decision to retain Mead Johnson within business portfolio Recent announcement to sell ConvaTec Confirmed 3 year non-GAAP guidance All GAAP to non-GAAP reconciliations are available on our website. This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 4
  • 5. Q1 2008 Sales: Growth Brands $1,400 $1,308 +39% $1,200 $1,000 $800 $M $600 $454 $400 +24% $297 $305 $273 $187 +13% +13% +21% $200 +17% $0 Plavix Abilify Avapro Reyataz Sustiva Erbitux This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 5
  • 6. Q1 2008 Sales: New Products $120 $108 +140% $100 $87 $80 +112% $66 $M $60 +314% $40 $25 $20 $0 Baraclude Orencia Sprycel Ixempra This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 6
  • 7. Plavix Indications Potential Patient Proven Efficacy and Safety Population ~49 million Indicated for use in broad patient population Other CV ~28 million Efficacy and safety of ACS / Stent Plavix well understood ~1.5 million ACS PAD Stroke Increased hospital ~3 million ~8 million ~10 million resources focused on risk benefit ACS / Non-Stent ~1.5 million Growth opportunities within ACS as well as stroke and PAD This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 7
  • 8. Abilify – Broad Clinical Profile and Specialty Execution Q1 global sales up 24% Broadest set of indications for any atypical US approval in major depressive disorder EU approval for bipolar mania Succesful DTC campaign This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 8
  • 9. Orencia – Goal to Become the IV Biologic of Choice Q1 sales $87 million +112% Focus on efficacy and durability of response Recent label change broadening indication regardless of prior treatment Promotional programs focused on compliance and persistence DTC campaign focused on defining inadequate response This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 9
  • 10. Our Productivity Approach Management Council Productivity Transformation Team Supply Chain R&D G&A Commercial Operations $400 MM $200 MM $550 MM $350 MM $1.5 Billion Cost Savings + Cost Avoidance This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 10
  • 11. Supply Chain Redesigned to Support BioPharma Model Strategic Filters Current 2011 27 Plants >50% Reduction Future Geographic Product Portfolio Footprint Rationalization Network segmented and specialized In-house Biologics capability Aggressive outsourcing of mature products Generating $400 Million in Productivity This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 11
  • 12. Customer Model Restructured to Support BioPharma 12,000 Primary Care 10,000 Specialty 8,000 Field-Based Medical FTEs Total Field Force 6,000 4,000 2,000 0 2005 2006 2007 2008 Specialty Model synergizes Sales Force and Field-Based Medical experts Partnering on Primary Care maximizes capacity and capability while minimizing fixed overhead Increasing productivity This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 12
  • 13. Key 2008 Events ASCO – Erbitux FLEX data – Sprycel phase II prostate data – Ipilimumab data ADA – Saxagliptin phase III data – Dapaglifozin phase IIb data EASD – Saxagliptin phase III data ASH – Apixiban phase III data This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 13
  • 14. Next Generation BioPharma Best of Pharma Best of Biotech Next Generation BioPharma Selectively Innovative Continuous Integrated Portfolio Improvement Business Model Agile, Entrepreneurial and Accountable Culture This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience- 14
  • 15. Lamberto Andreotti Executive Vice President & Chief Operating Officer Deutsche Bank Healthcare Conference May 7, 2008 This presentation is intended solely for an investment community/industry audience-not for promotional use community/industry audience-