The patient presented with symptoms of hyperthyroidism including weight loss, tachycardia, finger tremor, hypoxia, headache, fatigue, and eye flicker. Examination revealed a bright-red rash on the skin and swollen tonsils containing pus. The most probable diagnosis is scarlet fever based on the rash and tonsil findings. Laboratory tests showed an elevated osmotic pressure in the blood plasma, indicating increased secretion of the antidiuretic hormone vasopressin.

1. 1. A patient is followed up in an revealed localized bright-red hyperemia;
endocrinological dispensary on account of tonsils are swollen, soft, lacunas contain pus,
hyperthyreosis. Weight loss, tachycardia, finger tongue is crimson. Cervical lymph nodes are
tremor are accompanied by hypoxia enlarged, dense and painful. What is the
symptoms - headache, fatigue, eye flicker. most probable diagnosis?
What mechanism of thyroid hormones action A. Rubella
underlies the development of hypoxia? B. Scarlet fever
A. Intensification of respiratory ferment C. Infectious mononucleosis
synthesis D. Whooping cough
B. Inhibition of respiratory ferment synthesis E. Diphtheria
C. Specific binding of active centres of 6. A 45 y.o. woman suffers from Cushing's
respiratory syndrome - steroid diabetes. Biochemical
ferments examination revealed: hyperglycemia,
D. Disjunction, oxydation and phosphorilation hypochloremia. Which of the undermentioned
E. Competitive inhibition of respiratory processes is the first to be activated?
ferments A. Gluconeogenesis
2. A laboratory received a material from B. Glycolysis
a patient's wound. Ppreliminary diagnosis C. Glycogenolysis
is gaseous gangrene. What microbiological D. Glucose transport to the cell
method should be applied to determine E. Glucose reabsorption
species of causative agent? 7. Examination of an isolated cardiomyocyte
A. Bacteriological revealed that it didn't generate excitation
B. Allergic impulses automatically. This cardiomyocyte
C. Serological was obtained from:
D.RIA A. Sinoatrial node
E. Bacterioscopic B. Purkinje's fibers
3: A 4 y.o. child with signs of durative proteinic C. Ventricles
starvation was admitted to the hospital. D. Atrioventricular node
The signs were as follows: growth inhibition, E. His' bundle
anemia, edemata, mental deficiency Choose 8. Inhabitants of territories with cold climate
a cause of edemata development: . have high content of an adaptive
A. Reduced synthesis of albumins thermoregulatory hormone. What hormone
B. Reduced synthesis of hemoglobin is meant? .
C. Reduced synthesis of glycoproteins A. Insulin
D. Reduced synthesis of globulins B. Glucagon
E. Reduced synthesis of lipoproteins C. Throxin
4. A 45 y.o. patient consulted a doctor D. Cortisol
about plaque-shaped formation on his neck. E. Somatotropin
Histological examination of biopsy skin 9. As a result of damage to certain structures
material revealed tumourous cells of round of brainstem an animal lost orientation
and oval form with thin ring of basophilic reflexes. What structures were damaged?
cytoplasma that resemble of cells of basal A. Medial nuclei of reticular formation
epidermal layer. What tumour is it? B. Quadritubercular bodies
A. Hydradenoma C. Black substance
B. Epidermal cancer D. Reel nuclei
C. Trichoepithelioma E. Vestibular nuclei
D. Basalioma 10. According to the data of WHO, for about
E. Syringoadenoma 250 mln of Earth population fall ill with
5. A boy is 7 y.o. Objectively: against the malaria. This disease is mostly spread in
background of hyperemic skin there is tropical and subtropical regions. Range of
knobby bright-pink rash on his forehead, its spread falls into the areal of the following
neck, at the bottom of abdomen, in the mosquitoes:
popliteal spaces; nasolabial triangle is pale. A. Aedes
Examination of oropharyngeal surface B. Mansonia

2. C. Culex 16. A patient was diagnosed with active
D. Culiseta focal pulmonary tuberculosis. What drug
E. Anopheles should be prescribed in the first place?
11. A 35 y.o. patient who often consumes alcohol A. Ethionamide
was treated with diuretics. There B. Isoniazid
appeared serious muscle and heart C. Ethoxide
weakness, vomiting, diarrhea, AP- 100/60 D. Sulfalen
mm Hg, depression. This condition is caused E. Cyclocerine
by intensified excretion with urine of: 17. Examination of a young man in the AIDS
A. Potassium- centre produced a positive result of
B. Phosphates immune-enzyme assay with HIV antigens.
C. Chlorine Patient's complaints about state of his health
D. Sodium were absent. What can the positive result of
E. Calcium immune-enzyme assay be evidence of?
12. On the 6th day of treatment a patient A. HIV infection
with acute renal insufficiency developed B. Being infected with HBV
polyuria. Diuresis intensification at the beginning C. Having had AIDS recently
of polyuria stage of acute renal insufficiency D. Being ill with AIDS
is caused by: E. HBV persistence
A. Growth of natriuretic factor 18. RNA that contains AIDS virus
B. Reduction of aldosteron content in plasma penetrated into a leukocyte and by means
C. Reduction of vasopressin content in of reverse transcriptase forced a cell to
plasma synthetize a viral DNA. This process is
D. Renewal of filtration in nephrons based upon:
E. Volume expansion of circulating blood A. Operon repression
13. Osmotic pressure of a man's blood B. Operon depression
plasma is 350 mosmole/l (standard pressure C. Reverse transcription
is 300 mosmole/l). First of all it will result in D. Convariant replication
high secretion of the following hormone: E. Reverse translation
A. Vasopressin 19. A patient is ill with diabetes mellitus that
B. Adrenocorticotropin is accompanied by hyperglycemia of over 7,2
C. Cortisol millimole/l on an empty stomach. The level
D. Natriuretic of what blood plasma protein allows to estimate
E. Aldosteron the glycemia rate retrospectively (4-8
14. Neurological examination of a 65 y.o. weeks before examination)?
patient revealed a haemorrhage within the A. Ceruloplasmin
superior temporal gyrus. In the blood supply B. Glycated hemoglobin
area of which artery is it? C. Fibrinogen
A. Middle cerebral artery D. Albumin
B. Anterior communicating artery E. C-reactive protein
C. Anterior cerebral artery 20. A sportsman was recommended to take
D. Basilar artery a medication that contains carnitine in order
E. Posterior cerebral artery to improve his results. What process is activated
15. A 32 y.o. man is tall, he has gynecomastia, by carnitine the most?
adult woman pattern of hair distribution, high A. Synthesis of ketone bodies
voice, mental deficiency, sterility. Provisional B. Synthesis of steroid hormones
diagnosis is Klinefelter's syndrome. In C. Tissue respiration
order to specify diagnosis it is necessary to D. Fatty acids transport to mitochondrions
analize: E. Synyhesis of lipids
A. Leukogram 21. A patient consulted a doctor about
B. Genealogy bowels disfunction. The doctor established
C. Blood group symptoms of duodenitis and enteritis.
D. Spermatogenesis Laboratory examination helped to make the
E. Caryotype following diagnosis: lambliosis. What medication

3. should be administered? B. Hyaline degeneration
A. Tetracycline C. Carbohydrate degeneration
B. Monomycin D. Fatty vascular-stromal degeneration
C. Metronidazole E. Amyloidosis
D. Erythromycin 27. Labeled aminoacids alanine and
E. Chingamin tryptophane were introducted to a mouse
22. A man took a quiet expiration. Name an in order to study localization of protein
air volume that is meanwhile contained in biosynthesis in its cells. Around what
his lungs: organellas will the accumulation of labeled
A. Expiratory reserve volume aminoacids be observed?
B. Functional residual capacity A. Ribosomes
C. Residual volume B. Golgi apparatus
D. Vital lung capacity C. Agranular endoplasmic reticulum
E. Respiratory volume D. Cell centre
23. During pubescence the cells of male E. Lysosomes
sexual glands begin to produce male 28. 48 hours after performing tuberculin
sex hormon testosterone that calls forth test (Mantoux test) to a child a 10
secondary sexual characters. What cells of mm papule appeared on the spot of
male sexual glands produce this hormone? tuberculin introduction. What hypersensitivity
A. Sertoli's cells mechanism underlies these changes?
B. Leidig cells A. Antibody-dependent cytotoxicity
C. Sustentocytes B. Granulomatosis
D. Spermatozoa C. Cellular cytotoxicity
E. Supporting cells D. Immune complex cytotoxicity
24. A 16 y.o. boy from a countryside entered E. Anaphylaxis
an educational establishment. Scheduled 29. A patient who has been suffering from
Manteux test revealed that the boy had cardiac insufficiency for several months
negative reaction. What are the most has been taking digoxin on an outpatient
reasonable actions in this case? basis. At a certain stage of treatment there
A. To isolate the boy temporarily from his appeared symptoms of drug overdose. What
mates phenomenon underlies the development of
B. To perform serodiagnostics of tuberculosis this complication?
C. To perform BCG vaccination A. Functional cumulation
D. To perform rapid Price diagnostics B. Tachyphylaxis
E. To repeat the reaction in a month C. Habituation
25. Autopsy of a 56 y.o. man revealed in the D. Sensibilization
right temporal part of brain a big focus of E. Material cumulation
softened grey matter that was semi-liquid 30. Examination of a patient revealed
and light grey. Arteries of cerebral tela reduced contents of magnesium ions that
contain multiple whitish-yellow thiekenings are necessary for attachment of ribosomes
of intima that abruptly narrow the lumen. to the granular endoplasmatic reticulum.
What is your diagnosis? It is known that it causes disturbance of
A. Brain edema protein biosynthesis. What stage of protein
B. Brain abscess biosynthesis will be disturbed?
C. Hemorrhage A. Aminoacid activation
D. Hemorrhagic infarction B. Translation
E. Ischemic stroke C. Termination
26. Autopsy of a man who died from D. Replication
chronic cardiovascular collapse revealed E. Transcription
"tiger heart". Sidewards of endocardium 31. A child complains of general weakness,
a yellowish-white banding can be seen; loss of appetite, a troubled sleep, itching in
myocardium is dull, dark-yellow. What the perianal area. The provisional diagnosis
process caused this pathology? is enterobiasis. In order to specify this diagnosis
A. Fatty parenchymatous degeneration it is necessary to perform:

4. A. Roentgenoscopy C. Necrotic
B. Duodenal contents analysis D. Fibrinous
C. Scraping from perianal folds E. Catarrhal
D. Immune diagnostics 37. A 70 y.o. man has cut an abscess off
E. Biopsy of muscle tissue in the area of mammiform process during
32. In some regions of South Africa there is shaving. Two days later he was admitted
a spread sickle-shaped cell anemia, in which to the hospital with inflammation of
erythrocytes have shape of a sickle as a arachnoid membranes. How did the infection
result of substitution of glutamin by valine in penetrate into the cavity of skull?
the hemoglobin molecule. What is the cause A. V,v.auriculares
of this disease? B. V.v.labyrinthi
A. Genomic mutations C. V.facialis
B. Crossingover D. V.v.tympanicae
C. Gene mutation E. V.emissariae mastoideae
D. Transduction 38. 24 hours after appendectomy blood of a
E. Disturbance of mechanisms of genetic patient presents neutrophilic leukocytosis
information realization with regenerative shift. What is the
33. A patient suffers from vision impairment most probable mechanism of leukocytosis
- hemeralopy (night blindness). What vitamin development?
preparation should be administered A. Amplification of leukopoiesis
the patient in order to restore his vision? B. Decelerated leukocyte destruction
A. Thiamine chloride C. Redistribution of leukocytes in the organism
B. Tocopherol acetate D. Deceleratied emigration of leukocytes to
C. Retinol acetate the tissues
D. Vicasol E. Amplification of leukopoiesis and
E. Pyridoxine decelerated emigration of leukocytes to
34. A patient presents high activity of the tissues
LDH1.2 , aspartate aminotransferase, creatine 39. Examination of cell culture got from a
phosphokinase. In what organ (organs) is patient with lysosomal pathology revealed
the development of a pathological process accumulation of great quantity of lipids in
the most probable? the lysosomes. What of the following diseases
A. In the heart muscle (initial stage of is this disturbance typical for?
myocardium infarction) A. Phenylketonuria
B. In skeletal muscles (dystrophy, atrophy) B. Galactosemia
C. In kidneys and adrenals C. Gout
D. In liver and kidneys D. Tay-Sachs disease
E. In connective tissue E. Wilson disease
35. A woman who has been keeping to a 40. A group of mountain climbers went
clean-rice diet for a long time was diagnosed through the blood analysis at the height of
with polyneuritis (beriberi). What vitamin 3000 m. It revealed decrease of HCO3 to 15
deficit results in development of this disease? micromole/l (standard is 22-26 micromole/l).
A. Thiamine What is the mechanism of HCO3 decrease?
B. Pyridoxine A. Hypoventilation
C. Ascorbic acid B. Intensification of acidogenesis
D. Folic acid C. Hyperventilation
E. Riboflavin D. Decrease of bicarbonate reabsorption in
36. Colonoscopy of a patient ill with kidneys
dysentery revealed that mucous membrane E. Decrease of ammoniogenesis
of his large intestine is hyperemic, edematic, 41. A patient ill with diabetes mellitus felt
its surface was covered with grey-and-green acute pain in his right foot. Objectively: foot
coats. Name the morphological form of thumb is black, foot tissues are edematous.
dysenteric collitis: there are foci of epidermis desquamation,
A. Ulcerous stinking discharges. What clinicopathological
B. Purulent form of necrosis is it?

5. A. Infarction C. Decrease of ESR
B. Dry gangrene D. Hypercoagulation
C. Moist gangrene E. Increase of ESR
D. Bedsore 47. Histological examination of a 40 y.o.
E. Sequestrum man's thymus revealed decreased share of
42. Power inputs of a boy increased from 500 parenchymatous gland elements, increased
to 2000 kJ pro hour. What can be the cause share of adipose and loose connective tissue,
of it? its enrichment with thymus bodies.
A. Food intake The organ's mass was unchanged. What
B. Raise of outer temperatute phenomenon is it?
C. Mental activity A. Accidental involution
D. Transition from sleep to wakefulness B. Atrophy
E. Physical exercise C. Dystrophy
43. For the preparation of a patient`s D. Hypotrophy
burn skin surface a certain medication was E. Age involution
used. Its antiseptic action is provided by 48. A patient who suffers from cancer of
free oxygen that segregates in presence back of tongue has an intense bleeding as a
of organic substances. Choose the right result of affection of dorsal lingual artery by
answer: the tumour. What vessel should be ligated to
A. Potassium permanganate stop bleeding?
B. Chlorhexidine A. Facial artery
C. Sodium bicarbonate B. Dorsal lingual artery
D. Boric acid C. Ascending pharyngeal artery
E. Furacilin D. Lingual artery
44. Bacteriological examination of a patient E. Deep lingual artery
with food poisoning required inoculation of 49. In course of indirect histogenesis of
a pure culture of bacteria with the following tubular bone tissue a plate is formed
properties: gram-negative movable bacillus between epiphyseal and diaphyseal ossification
that grows in the Endo's medium in form of centres that provides further
colourless colonies. A representative of which lengthwise growth of bones. What structure
species caused this disease? is it?
A. Esherichia A. Osseous plate
B. Salmonella B. Metaphyseal plate
C. Shigella C. Osteon
D. Citrobacter D. Osseous cuff
E. Iersinia E. Layer of interior general plates
45. A lymph node punctate of a patient with 50. A man with cut wound of his right foot
suspected protozoal disease was examined. sole was admitted to the hospital ward. The
Examination of the stained specimen patient has limited elevation of the lateral
(Romanovsky's stain) revealed some foot edge. In course of wound management
crescent bodies with pointed end, blue the injury of a muscle tendon was revealed.
cytoplasm and red nucleus. What protozoan What muscle is injured?
were revealed in the smears? A. Triceps muscle of crus
A. Viscerotropic leishmania B. Long extensor muscle of toes
B. Toxoplasms C. Long peroneal
C. Trypanosomes D. Short peroneal
D. Malarial plasmodiums E. Anterior tibial
E. Demtropic leishmania 51. After resection of the middle third of
46. Long-term starvation cure of a patient femoral artery obliterated by a thromb the
resulted in diminished ratio of albumines lower extremity is supplied with blood due
and globulines in plasma. What of the to the surgical bypass. Name an artery that
following will be result of these changes? plays the main role in reestablishment of
A. Decrease of hematocrit blood flow:
B. Increase of hematocrit A. Deep femoral artery

6. B. Deep external pudendal artery branches of carotid artery. For a temporary arrest
C. Descending genicular artery of bleeding it is necessary to press the
D. Superficial circumflex artery of hip bone carotid artery to the tubercle of a cervical
E. Superficial epigastric artery vertebra. Which vertebra is it?
52. An experimental animal was first sensibilized A.VI
whereupon an antigen dose was B. II
introduced subcutaneously. This injection C. IV
resulted in the development of a fibrinous D. III
inflammation with alteration of vessel E. V
walls, basal substance and fibrous structures 57. Reaction of passive hemagglutination
of connective tissue in form of mucoid conducted with erythrocytic typhoid
and fibrinoid swelling and necrosis. What Vidiagnosticum
immunological reaction took place? helped to reveal some antibodies
A. Immediate hypersensitivity in the dilution of the patient's serum
B. Granulomatosis at a ratio of 1:80 that exceeds the diagnostic
C. Reaction of transplantation immunity titer. Such result witnesses of:
D. Delayed-type hypersensitivity A. Typhoid fever recurrence
E. Normergic reaction B. Being a potential carrier of typhoid bacilli
53. Autopsy of a patient who suffered C. Being ill with acute typhoid fever
from croupous pneumonia and died from D. Incubation period of typhoid fever
pneumococcal sepsis revealed 900 ml of E. Reconvalescence of a patient ill with
turbid greenish-yellow liquid in the right typhoid fever
pleural cavity. Pleural leaves are dull, 58. A patient with clinical presentations
plephoric. Name the clinicopathological of immunodeficiency went through
form of inflammation in the pleural cavity: immunological examinations. They revealed
A. Acute abscess significant loss of cells that form rosettes with
B. Empyema erythrocytes of a ram. What conclusion
C. Phlegmon can be made according to the analysis data?
D. Fibrinous inflammation A. Decrease of natural killer cell rate
E. Chronic abscess B. Decrease of T-lymphocytes rate
54. A patient was delivered to the hospital C. Insufficiency of effector cells of humoral
by an emergency team. Objectively: immunity
grave condition, unconscious, adynamy. D. Decrease of B-lymphocytes rate
Cutaneous surfaces are dry, eyes are sunken, E. Decrease of complement system rate
face is cyanotic. There is tachycardia and 59. Examination of a 60 y.o. patient revealed
smell of acetone from the mouth. Analysis hyperglycemia and glucosuria. A doctor
results: blood glucose - 20,1 micromole/l administered him a medication for internal
(standard is 3,3-5,5 micromole/l), urine use. What medication is it?
glucose - 3,5% (standard is - 0). What is the A. Oxytocin
most probable diagnosis? B. Corglycon
A. Hypoglycemic coma C. Furosemide
B. Acute heart failure D. Pancreatine
C. Anaphylactic shock E. Glibenclamid
D. Hyperglycemic coma 60. In order to estimate toxigenity of diphtheria
E. Acute alcoholic intoxication agents obtained from patients the
55. A patient has a disturbed absorbtion of cultures were inoculated on Petri dish with
fat hydrolysates. It might have been caused nutrient agar on either side of a filter paper
by a deficit in the small intestine cavity: strip that was put into the centre and moistened
A. Of bile pigments with antidiphtherie antitoxic serum.
B. Of sodium ions After incubation of inoculations in agar the
C. Of bile acids strip-like areas of medium turbidity were
D. Of lipolytic enzymes found between separate cultures and the
E. Of liposoluble vitamins strip of filter paper. What immunological
56. An injured man has bleeding from reaction was conducted?

7. A. Opsonization reaction E. 70
B. Coomb's test 66. A 40 y.o. patient complains of intensive
C. Agglutination reaction heartbeats, sweating, nausea, vision impairment,
D. Rings precipitation reaction arm tremor, hypertension. From his
E. Precipitation gel reaction anamnesis: 2 years ago he was diagnosed with
61. A woman with III (B), Rhˉ blood group pheochromocytoma. Hyperprocduction of
born a child with II (A) blood group. The what hormones causes the given pathology?
child is diagnosed with hemolytic disease of A. ACTH
newborn as a result of rhesus incompatibility. B. Thyroid hormones
What blood group is the child's father C. Aldosterone
likely to have? D. Glucocorticoids
A. I (0). Rh + E. Catecholamines
B. III (B). Rh+ 67.Mucous membrane of the right palatine tonsil
C. I (0), Rh- has a painless ulcer with smooth lacquer fundus
D. II (A), Rh- and regular cartilaginous edges. Microscopically:
E. II (A), Rh+ inflammatory infiltration that consists of
62. A 12 y.o. boy who suffers from bronchial lymphocytes, plasmocytes, a small number of
asthma has an acute attack of asthma: evident neutrophils and epithelioid cells; endovasculitis
expiratory dyspnea, skin pallor. What and perivasculitis. What disease is it?
type of alveolar ventilation disturbance is it? A. Actinomycosis
A. Central B. Pharyngeal diphtheria
B. Neuromuscular C. Ulcerous necrotic Vincent’s angina
C. Throracodiaphragmatic D. Tuberculosis
D. Restrictive E. Syphilis
E. Obstructive 68. For the purpose of retrospective diagnostics of
63. A patient diagnosed with carcinoid recent bacterial dysentery it was decided to
of bowels, was admitted to the hospital. perform serological examination of blood serum
Analysis revealed high production of in order to determine antibody titer towards Shiga
serotonin. It is known that this substance bacilli. What of the following reactions should be
is formed of tryptophane aminoacid. applied?
What biochemical mechanism underlies this A. Passive hemagglutination
process? B. Bordet-Gengou test
A. Microsomal oxydation C.Hemolysis
B. Formation of paired compounds D. Precipitation
C. Desamination E. Bacteriolysis
D. Decarboxylation 69. Autopsy of a 48 y.o. man revealed a round
E. Transamination formation 5 cm in diameter with clear-cut
64. Examination of a patient revealed an outlines in the region of the 1st segment of his
abscess of pterygopalatine fossa. Where can right lung. This formation was encircled with a
the infection spread to unless the disease is thin layer of connective tissue full of white brittle
managed in time? masses. Make a diagnosis of the secondary
A. To the orbit tuberculosis form:
B. To the subgaleal temporal space A. Fibrous cavernous tuberculosis
C. To the tympanic cavity B. Tuberculoma
D. To the interpterygoid space C. Acute focal tuberculosis
E. To the frontal sinus D. Caseous pneumonia.
65. Examination of a man established that E. Acute cavernous tuberculosis
cardiac output equaled 3500 ml, systolic 70. A man’s intrapleural pressure is being
output - 50 ml. What is the man's heart rate measured. In what phase did the man hold his
pro minute? breath, if his pressure is 7,5 cm Hg?
A.60 A. Forced expiration
B.90 B. Quiet inspiration
C. 50 C. –
D. 80 D. Quiet expiration

8. E. Forced inspiration B. Fibrinous inflammation
71. In the surgical department of a hospital there C. Hyalinosis
was an outbreak of hospital infection that showed D. Mucoid swelling
itself in often postoperative wound abscesses. E. Amyloidosis
Bacteriological examination on of pus revealed 76. In course of an operation surgeon
aurococcus. What examination shall be conducted removed a part of a lung that was ventilated
to find out the source of this causative agent by a tertiary bronchus accompanied
among the department personnel? by branches of pulmonary artery and other
A. Serological identification vessels. What part of a lung was removed?
B. Microscopical examination A. Middle lobe
C. Phagotyping B. Bronchopulmonary segment
D. Biochemical identification C. Superior lobe
E. Estimation of antibiotic susceptibility D. Inferior lobe
72. Heart rate of a man permanently E. Pulmonary lobule
equals 40 beats pro minute. What is the 77. Vitamin A deficit results in the impairment
pacemaker? of twilight vision. Name the cells that
A. His' bundle have the above-mentioned photoreceptor
B. Purkinje's fibers function:
C. His' bundle branches A. Ganglion neurocytes
D. Sinoatrial node B. Rod receptor cell
E. Atriventricular node C. Cone receptor cells
73. A 4 y.o. boy has had recently serious D. Horizontal neurocytes
viral hepatitis, Now there are such E. Bipolar neurons
clinical presentations as vomiting, loss of 78. Microscopical examination of a removed
consciousness, convulsions. Blood analysis appendix revealed an edema, diffuse
revealed hyperammoniemia. Disturbunce neutrophilic infiltration of appendix wall
of which biochemical process caused such along with necrosis and defect of mucous
pathological condition of the patient? membrane with affection of its muscle plate.
A. Disturbed neutralization of ammonia in What appendicitis form was developed?
liver A. Gangrenous
B. Inhibition of transamination enzyms B. Ulcerophlegmonous
C. Increased putrefaction of proteins in C. Apostematous
bowels D. Superficial
D. Activation of aminoacid decarboxylation E. Phlegmonous
E. Disturbed neutralization of biogenic 79. Introduction of a pharmaceutical
amines substance to an experimental animal
74. An experimental rat with extremity resulted in reduction of salivation, pupil
paralysis has no tendon and cutaneous mydriasis. Next intravenous introduction of
reflexes, muscle tone is decreased, but acetylcholine didn't lead to any significant
muscles of the affected extremity maintain changes of heart rate. Name this substance:
their ability to react with excitation to the direct A. Proserin
action of continious current. What type B. Atropine
of paralysis is it? C. Propranolol
A. Spastic peripheral D. Adrenaline
B. Spastic central E. Salbutamol
C. Extrapyramidal 80. Examination of a 43 y.o, anephric patient
D. Flaccid peripheral revealed anemia symptoms. What is the
E. Flaccid central cause of these symptoms?
75. Autopsy of a 58 y.o, man revealed that A. Folic acid deficit
bicuspid valve was deformed, thickened and B. Iron deficit
unclosed. Microscopically: foci of collagen C. Reduced synthesis of erythropoietins
fibrilla are eosinophilic, react positively to D. Vitamin B12 deficit
fibrin. The most probably it is: E. Enhanced destruction of erythrocytes
A. Fibrinoid swelling 81. Examination of a newborn boy's genitals

9. revealed a cleft of urethra that opens retrosternal pain a patient presented a jump
on the inferior surface of his penis. What of aspartate aminotransferase activity in
developmental anomaly is it? blood serum. What pathology is this deviation
A. Cryptorchism typical for?
B. Epispadia A. Myocardium infarction
C. Monorchism B. Viral hepatitis
D. Hennaphroditism C. Diabetes mellitus
E. Hypospadia D. Collagenosis
82. A patient ill with collagenesis has E. Diabetes insipidus
been taking prednisolone for a long time. 87. A peripheral segment of vagus nerve on
Hypokaliemia development caused spastic pain of a dog's neck was being stimulated in course
skeletal muscles. What medication of an experiment. The following changes
should be used in order to correct potassium of cardiac activity could be meanwhile
exchange? observed:
A. Dithylinum A. Heart rate and heart force amplification
B. Panallgin B. Enhancement of atrioventricular
C. Thyrocalcitonin conduction
D. Diazepam C. Heart rate fall
E. Noshpa D. Heart hurry
83. From pharynx of a child with suspected E. Increased excitability of myocardium
diphtheria a pure culture of microorganisms 88. A 39 y.o. woman went through an
was isolated. Their morphological tinctorial, operation in course of which surgeons
cultural and biochemical properties removed her uterine tube that was enlarged
appeared to be typical for diphtheria and a part of an ovary with a big cyst.
causative agents. What study should be Histological examination of a tube wall
conducted in order to drow a conclusion that revealed decidual cells, chorion villi. What
this is a pathogenic diphtheria bacillus? was the most probable diagnosis made after
A. Estimation of proteolytic properties examination of the uterine tube?
B. Estimation of urease activity A. Tubal pregnancy
C. Estimation of cystinous activity B. Placental polyp
D. Estimation of ability to decompose starch C. Papyraceous fetus
E. Estimation of toxigenic properties D. Lithopedion
84. A man was admitted to the hospital E. Choriocarcinoma
on the 5th day of disease that manifested 89. A forensic medical expert examines
itself by jaundice, muscle aching, chill, nose the body of a 58 y.o. man who had been
bleedings. In course of laboratory diagnostics consuming large amounts of alcochol for a
a bacteriologist performed dark-field microscopy long time and died at home. Microscopicaly:
of the patient's blood drop. Name the right lung is dense and enlarged, its incision
a causative agent of this disease: revealed that the tissue is greyish and
A. Leptospira interrogans homogenous, pleura is covered with greyish
B. Bartinella bacilloformis layers. Microscopically - alveolar cavities
C. Calymmatobacterium granulomatis contain fibrin, hemolyzed erythrocytes.
D. Rickettsia mooseri Make a diagnosis:
E. Borrelia dutlonii A. Focal pneumonia
85. Nappies of a newborn have dark spots B. Caseous pneumonia
that witness of formation of homogentisic C. Interstitial pneumonia
acid. Metabolic imbalance of which D. Primary pulmonary tuberculosis
substance is it connected with? E. Croupous pneumonia
A. Methionine 90. A 40 y.o. woman was admitted to the
B. Thyrosine infectious diseases department with high
C. Galactose body temperature. Objectively: evident
D. Tryptophane meningeal symptoms. A spinal cord punction
E. Cholesterine was made. What anatomic formation was
86. 12 hours after an accute attack of punctured?

10. A. Cisterna cerebellomedullaris posterior tissue will be inhibited?
B. Spatium subdurale A. Of fibroblasts
C. Spatium epidurale B. Of pericytes
D. Spatium subarachnoideum C. Of pigment cells
E. Cavum trigeminale D. Of lipocytes
91. A patient with II stage hypertension has E. Of macrophags
been taking one of hypotensive medications 96. 6 months after delivery a woman had
for the purpose of treatment. After a time uterine bleeding. Gynecological examination
arterial pressure decreased, but the patient revealed in the uterine cavity a dark-red
started complaining of flaccidity, sleepiness, tissue with multiple cavities that resembled
indifference. A bit later he felt stomach of "sponge". Microscopic examination of
pain. He was diagnosed with ulcer. What the tumour revealed some atypic light epithelial
hypotensive medication has the patient been Langhans cells and giant cells of
taking? cyncytiotrophoblast in blood lacunas. What
A. Captopril tumour is it?
B. Dibazoie A. Vesicular mole
C. Reserpine B. Fibromyoma
D. Furosemide C. Adenocarcinoma
E. Verapamil D. Squamous cell nonkcratinous carcinoma
92. A patient had to go through an operation. E. Chorioepithelioma
Doctors introduced him dithylinum 97. A 50 y.o. patient with chronic cardiac
(listenone) and performed intubation. insufficiency and tachyarrythmia was
After the end of operation and cessation prescribed a cardiotonic drug. What drug
of anesthesia the independent respiration wasn't was prescribed?
restored. Which enzyme deficit A. Dobutamine
prolongs the action of muscle relaxant? B. Mildronate
A. Pseudocholinesterase C. Amyodarone
B. K-Na-adenosine triphosphatase D. Digoxin
C. N - acetyltransferase E. Dopamine
D. Succinate dehydrogenase 98. A young man consulted a doctor about
E. Carbanhydrase disturbed urination. Examination of his
93. Ammonia is a very toxic substance, external genitals revealed that urethra is
especially for nervous system. What split on top and urine runs out of this
substance takes the most active part 111 opening. What anomaly of external genitals
ammonia detoxication in brain tissues? development is the case?
A. Glutamic acid A. Paraphimosis
B. Alanine B. Epispadia
C. Proline C. Hypospadia
D. Histidine D. Hermaphroditism
E. Lysine E. Phimosis
94. A child's blood presents high content 99. Violation of safety rules resulted in
of galactose, glucose concentration is low. calomel intoxication. Two days later the
There are such presentations as cataract, daily diuresis was 620 m1. A patient
mental deficiency, adipose degeneration of experienced headache, vomiting, convulsions,
liver. What disease is it? dyspnea, moist rales in lungs. What
A. Galactosemia pathology is it?
B. Steroid diabetes A. Acute renal insufficiency
C. Lactosemia B. Chronic renal insufficiency
D. Diabetes mellitus C. Uraemic coma
E. Fructosemia D. Pyelonephritis
95. In course of an experiment a big number E. Glomerulonephritis
of column cells of red bone marrow was in 100. A patient has a transverse disruption of
some way destructed. Regeneration of which cell spinal cord below the IV thoracic segment.
populations in the loose connective What changes of respiration will it cause?

11. A. Respiration will become more frequent C. Melancholic
B. Respiration will stay unchanged D. Sanguine
C. Respiration will stop E. -
D. Respiration will become less frequent 106. A patient suffers from hepatic cirrhosis.
E. Respiration will become deeper Examination of which of the following
101. A patient with a stab wound of the substances excreted by urine can characterize
anterior stomach wall is in surgical care. the state of antitoxic function of liver?
What formation of abdominal cavity did the A. Hippuric acid
stomach contents get into? B. Ammonium salts
A. Right mesenteric sinus
C. Aminoacids
B. Hepatic bursa
C. Omental bursa D. Kreatinine
D. Left mesenteric sinus E. Uric acid
E. Antegastrial bursa 107. Examination of a child revealed some
102. A patient with infectious mononucleosis whitish spots looking like coagulated milk
has been taking glucocorticoids for two on the mucous membrane of his cheeks and
weeks. He was brought into remission, but tongue. Analysis of smears revealed grampositive
he fell ill with acute attack of chronic tonsillitis. oval yeast-like cells. What causative
What action of glucocorticoids caused agents are they?
this complication? A. Actinomycetes
A. Anti-inflammatory B. Staphylococci
B. Immunosuppressive C. Candida
C. Antiallergic D. Fusobacteria
D. Antishock E. Diphtheria bacillus
E. Antitoxic 108. A patient's knee joint doesn't extend,
103. Removal of gall bladder of a patient there is no knee-jerk ref1ex, skin sensitivity
has disturbed processes of Co absorption of the anterior femoral surface is disturbed.
through the intestinal wall. What vitamin What nerve structures are damaged?
will stimulate this process? A. Superior gluteal nerve
A. B12 B. Femoral nerve
B. PP C. Big fibular nerve
C. C D. Inferior gluteal nerve
D. K E. Obturator nerve
E. D3 109. A patient has pain, edema and reddening
104. A 9 m.o. child has delayed dentition, it of his skin in the anterosuperior area of
is also out of order. Upper jaw configuration his thigh and his foot's thumb. What lymph
is horizontal ("high palate); microscopically nodes of his lower extremity responded to
- irregular mineralization of tooth enamel, the inflammatory process?
wrinkled enamel prisms, some of them are A. Deep inguinal
vacuolized. Predentin zone is extended; B. Superficial longitudinal
there are solitary denticles. What disease C. Superficial inguinal
is it? D. lnternal longitudinal
A. Late rickets E. General longitudinal
B. Early rickets 110. Examination of a 43 y.o. patient
C. Hypervitaminosis D revealed that his stomach has difficulties with
D. Gout digestion of protein food. Gastric juice
E. Osteon1alacia analysis revealed low acidity. Function of
105. Examination of a patient revealed which gastric cells is disturbed in this case?
a strong, balanced, inert type of higher A. Main exocrinocytes
nervous activity according to Pavlov. What B. Parietal exocrinocytes
temperament type does the patient have C. Mucous cells (mucocytes)
(according to Hiprocrates classification)? D. Endocrinous cells
A. Phlegmatic E. Cervical mucocytes
R Choleric 111. The permeability of the irritable cell

12. membrane has been increased for potassium C. Lactin and myosin synthesis
ions during an experiment. What changes of D. Regulation of Ca2+ rate in mitochondrions
membrane electric status can occur? E. Substrate phosphorylation
A. Action potential 117. A 30 y.o. woman had been ill for a
B. No changes year when she felt pain in the area of joints
C. Hyperpolarization for the first time, they got swollen and
D. Local response skin above them became reddened. Provisional
E. Depolarization diagnosis is rheumatoid arthritis. One
112. An ovary specimen stained by of the most probable causes of this disease is
hematoxylin-eosin presents a follicle, where a structure alteration of a connective tissue
cells of follicular epithelium are placed in protein:
1-2 layers and have cubic form, there is a A. Collagen
bright-red membrane around the ovocyte. B. Troponin
What follicle is it? C. Ovoalbumin
A. Secondary D. Mucin
B. Atretic E. Myosin
C. Primordial 118. A 56 y.o. patient has been suffering from
D. Primary thyreotoxicosis for a long time. What type of
E. Mature hypoxia can be developed?
113. Utilization of arachidonic acid via A. Tissue
cyclooxigenase pathway results in formation B. Hemic
of some bioactive substances. Name them: C. Circulatory
A. Prostaglandins D. Respiratory
B. Biogenic amins E. Mixed
C. Insulin-like growth factors 119. A 48 y.o. patient was admitted to the
D. Somatomedins hospital with complaints about weakness,
E. Thyroxine irritability, sleep disturbance. Objectively:
114. A woman has been applying a new skin and scleras are yellow. In blood:
cosmetic preparation for a week that conjugated bilirubin, cholalemia. Feces are
resulted in eye-lid inflammation accompanied acholic. Urine is of dark colour (bilirubin).
by hyperemia, infiltration and painfulness. What jaundice is it?
What type of allergic reaction was A. Mechanic
developed? B. Crigler-Najjar syndrome
A.IV C. Hemolytic
B. I D. Parenchymatous
C. III E. Gilbert's syndrome
D.V 120. A lightly dressed man is standing in a
E. II room, air temperature is +14°C, windows
115. A doctor administered a patient with and doors are closed. In what way does he
allergic dermatitis a H1 -histamine blocker emit heat the most actively?
as a part of complex treatment. Name this A. Perspiration
medication: B. Heat conduction
A. Prednisolone C. Heat radiation
B. Loratadine D. Convection
C. Cromolyn sodium E. Evaporation
D. Hydrocortisone 121. A patient complains of pain in the area
E. Adrenaline of his liver. Duodenal intubation revealed
116. A 1 y.o. child with symptoms of muscle yellowish, oval, narrowed at the poles eggs
affection was admitted to the hospital. with an operculum at the end. Size of these
Examination revealed carnitine deficit in eggs is the smallest among all helminth eggs.
muscles. Biochemical base of this pathology What is the most probable diagnosis?
is disturbed process of: A. Beef tapeworm infection
A. Transporting of fatty acids to mitochondrions B. Diphyllobothriasis
B. Lactic acid utilization C. Echinococcosis

13. D. Teniasis a worker has largely reduced buffer capacity
E. Opisthorchosis of blood. What acidic substance that came
122. A patient who suffers from severe disorder to blood caused this phenomenon?
of water-salt metabolism experienced A. -
cardiac arrest in diastole. What is the most B. l,3-bisphosphoglycerate
probable mechanism of cardiac arrest in diastole? C. 3-phosphoglycerate
A. Hypernatremia D. Pyruvate
B. Hyponatremia E. Lactate
C. Hypokaliemia 128. Bacteriological laboratory examines
D. Organism dehydratation canned meat whether it contains botulinum
E. Hyperkaliemia toxin. For this purpose an extract of test
123. A 36 y.o. man has a craniocerebral specimen and antitoxic antibotulinic scrum
trauma. Objectively: diminished breath of A, B, E types were introducted to a group
sounds, thready pulse, no reflexes. What way of mice under examination; a control group
of pyracetam introduction will be the most of mice got the extract without antibotulinic
apropriate in this case? serum. What serological reaction was applied?
A. Subcutaneous A. Complement binding
B. Intravenous B. Precipitation
C. Inhalation C. Opsono-phagocytic
D. Rectal D. Neutralization
E. Peroral E. Double immune diffusion
124. Short-term physical activity resulted in 129. Parents of a 10 y.o. boy consulted a
reflex amplification of heart rate and raise of doctor about extension of hair-covering,
systemic arterial pressure. What receptors growth of beard and moustache, low voice.
activation was the main cause of pressor Intensified secretion of which hormone
reflex realization? must be assumed?
A. Vascular chemoreceptors A. Of testosterone
B. Vascular volume receptors B. Of somatotropin
C. Proprioreceptors of active muscles C. Of cortisol
D. Hypothalamus thermoreceptors D. Of oestrogen
E. Vascular baroccptors E. Of progesterone
125. A patient with neuritis of femoral nerve 130. A 60 y.o. patient has a reduced
has disturbed flexion of thigh as well as disturbed perception of high-frequency sounds. What
crus extension in the knee joint. structures' disorder of auditory analizer
What muscle's function is disturbed? caused these changes?
A. Quadriceps muscle of thigh A. Main membrane of cochlea near helicotrema
B. Semitendinous muscle B. Main membrane of cochlea near the oval
C. Triceps muscle of thigh window
D. Biceps muscle of thigh C. Muscles of middle ear
E. Semimembranous muscle D. Eustachian tube
126. A 55 y.o. woman consulted a doctor about E. Tympanic membrane
having continuous cyclic uterine 131. In course of an experiment a skeletal
hemorrhages for a year, weakness, dizziness. muscle is being stimulated by a series of
Examination revealed skin pallor. electric impulses. What type of muscle
Hcmogram: Hb- 70 g/L erythrocytes 3.2*1012/l, contraction will arise, if every subsequent
color index - 0,6, leukocytcs 6.0*109/l, impulse comes in the period of relaxation of
reticulocytes - 1%; erythrocyte single muscle contraction?
hypochromia. What anemia is it? A. Muscle contructure
A. Hemolytic anemia B. A series of single contractions
B. B12 -folate-deficiency anemia C. Holotetanus
C. Chronic posthemorrhagic anemia D. Asynchronous tetanus
D. Iron-deficiency anemia E. Partial tetanus
E. Aplastic anemia 132. A liquidator of a breakdown at a
127. As a result of exhausting muscular work nuclear power plant who was irradiated

14. complained about vomiting that occurs all E. Lisosomes
of a sudden. What medication should be 137. A 22 y.o. woman has enlarged lymph
prescribed? nodes. Histologlcally: a lymph node contains
A. Metoclopramide lymphocytes, histiocytes, reticular cells,
B. Aeron small and big Hodgkin's cells, multinucleated
C. Reserpine Sternberg cells, isolated foci of
D. De-Nol caseous necrosis. What disease are these
E. Atropine changes typical for?
133. A patient got a craniocerebral trauma A. Lung cancer metastasis
that resulted in right-side convergent strabismus. B. Chronic leukosis
Damage of which craniocerebral C. Acute leukosis
nerve caused such consequences? D. Lymphogranulomatosis
A. n.facialis E. Lymphosarcoma
B. n.trigeminus 138. A 49 y.o. woman consulted a doctor
C. n.aculomotorius about heightened fatigue and dyspnea during
D. n.trochlearis physical activity. ECG: heart rate is
E. n.abducens 50/min, PQ is extended, QRS is unchanged,
134. A patient ill with bronchial asthma didn't P wave quanity exceeds quantity of QRS
inform his doctor that he had attacks complexes. What type of arrhythmia does
of stenocardia. Doctor administered him a the patient have?
medication, which taking resulted in less A. Extrasystole
frequent attacks of bronchial asthma. but B. Sinoatrial block
stenocardia attacks became more frequent. C. Sinus bradycardia
What medication was administered? D. Atrioventricular block
A. Cromolyn sodium E. Ciliary arhythmia
B. Salbutamol 139. A patient who suffers from pneumonia
C. Aminophylline has high body temperature. What biologically
D. Phenotherol active substance plays the leading part
E. Isadrin in origin of this phenomenon?
135. Autopsy of a man who died from A. Bradykinin
influenza revealed that his heart was slightly B. Leukotrienes
enlarged, pastous, myocardium was C. Histamine
dull and had specks. Microscopical cxamination D. Serotonin
of myocardium revealed signs of E. Interleukin-I
parenchymatous adipose and hydropic 140. A teenager was irradiated with high
dystrophy; stroma was edematic with poor radiation dose that resulted in serious
macrophagal and lymphocytic infiltration, damages of lymphoid system, lysis of
vessels were plethoric; perivascular analysis many lymphocytes. Restoration of normal
revealed petechial hemorrhages. What type hemogram is possible due to the functioning
of myocarditis was developed in this case? of the following gland:
A. Serous diffuse A. Thyroid
B. Granulomatous B. Adrenal
C. Purulent C. Liver
D. Interstitial proliferative D. Thymus
E. Serous focal E. Pancreas
136. In course of practical training students 141. In course of histidine catabolism a biogenic
studied a stained blood smear of a mouse with amin is formed that has powerful
bacteria phagocyted by leukocytes. What vasodilatating effect. Name it:
cell organella completes digestion of these A. Histamine
bacteria? B. Dopamine
A. Mytochondrions C. Dioxyphenylalanine
B. Ribosomes D. Noradrenalin
C. Golgi apparatus E. Serotonin
D. Granular endoplasmic reticulum 142. According to audiometry data a patient

15. has a disturbed perception of mediumfrequency A. Spinothalamic
sounds. It might have been caused B. Medial spinocortical
by a damage of: C Anterior spinocerebellar
A. Cochlear nuclei D. Posterior spinocerebellar
B. Quadritubercular structure E. Lateral spinocortical
C. Middle part of helix 147. A patient who suffers from heart failure
D. Lateral geniculate bodies has enlarged liver, edemata of lower
E. Spiral ganglion extremities, ascites. What is the leading
143. A patient with fracture of his lower mechanism in the development of this
jaw was admitted to the maxillofacial edema?
department. It was decided to fix his A. Hydrodynamic
bones surgically under anaesthetic. After B. Membranogenic
intravenous introduction of muscle relaxant C-
there arose short fibrillar contractions of D. Lymphogenous
the patient's facial muscles. What muscle E. Colloid osmotic
relaxant was applied? 148. A rabbit's nerve that innervates the
A. Dithylinum right ear was cut and its right superior
B. Pipecuronium bromide cervical ganglion was removed. Immediately
C. Diazepam after operation the temperature of
D. Melictine ear skin was measured. It was revealed that
E. Tubocurarin chloride the temperature of the rabbit's ear skin on
144. Analysis of blood serum of a patient the side of denervation was by 1,5°C higher
revealed increase of alanine than on the opposite intact side. What of the
aminotransferase and aspartate aminotransferase following is the most probable explanation
level. What cytological of the above-mentioned effects?
changes can cause such a situation? A. Atrerial hyperemia induced by metabolic
A. Disturbance of cellular interrelations factors
B. Cellular breakdown B. Arterial neuroparalytic hyperemia
C Disturbance of genetic apparatus of cells C. Arterial neurotopical hyperemia
D. Disturbed function of energy supply of D. Reactive arterial hyperemia
cells E. Physiological arterial hyperemia
E. Disorder of enzyme systems of cells 149. Inflammation of a patient's eye was
145. A 63 y.o. man fell ill with acute tracheitis accompanied by accumulation of turbid liquid
and bronchitis accompanied by bronchial with high protein at the bottom of
pneumonia. On the l0th day the patient anterior chamber that was called hypopyon.
died from cardiopulmonary insufficiency What process underlies the changes under
Autopsy revealed fibrinous hemorrhagic observation?
laryngotracheobronchitis: lungs were A. Primary alteration
enlarged. their incision revealed-the "coalminer's" B. Proliferation
effect caused by interlacing of sections C.-
of bronchial pneumonia. hemorrhages D. Secondary alteration
into the pulmonary parenchyma, acute E. Disturbance of microcirculation
abscesses and atelectases. Internal organs 150. A patient was ill with burn disease that
have discirculatory and dystrophic changes. was complicated by DIC syndrome. What
What is the most probable diagnosis? stage of DIC syndrome can he suspected if it
A. Moderately severe influenza IS known that the patient's blood coagulates
B. Adenoviral infection in less than 3 minutes?
C Parainfluenza A. Terminal
D. Influenza. severe form B. Transition phase
E. Respiratory syncytial infection C. Hypocoagulation
146. As a result of spinal-cord trauma D. Hypercoagulation
a 33 y.o. man has a disturbed pain and E. Fibrinolysis
temperature sensitivity that is caused by 151. An experimental animal has been given
damage of the following tract: excessive amount of carbon-Iabeled glucose

16. for a week. What compound can the label B. Supracutaneous tularin test
be found in? C. Mantoux test
A. Methionine D. Burnet test
B. Arachidonic acid E. Anthraxine test
C. Palmitic acid 157. A patient has extrasystole. ECG shows
D. Choline no P wave, QRS complex is deformed,
E. Vitamin A there is a full compensatory pause. What
152. A patient complains of dryness of extrasystoles are these?
head skin, itching, fragility and loss of hair. A. Atrioventricular
After examination he was diagnosed with B. Sinus
seborrhea. Disturbed activity of which cells C. Ventricular
caused this condition? D. Atrial
A. Cells of sudoriferous glands E. -
B. Melanocytes 158. After intake of rich food a patient
C. Adipocytes feels nausea and sluggishness; with time
D. Epithelial cells there appeared signs of steatorrhea.
E. Cells of sebaceous glands Blood cholesterine concentration is 9,2
153. A patient who had been working hard micromole/l. This condition was caused by lack
under conditions of elevated temperature of:
of the environment, has now a changed A. Fatty acids
quantity of blood plasma proteins. What B. Bile acids
penomenon is the case? C. Phospholipids
A. Paraproteinemia D. Chylomicrons
B. Absolute hyperproteinemia E. Triglycerides
C. Disproteinemia 159. A 27 y.o. patient put eye drops
D. Relative hyperproteinemia that contain penicillin. After a few minutes
E. Absolute hypoproteinemia she felt itching and burning of
154. Examination of a patient revealed her body, there appeared lip and eye-lid
extremely myotic pupils, sleepiness, edemata; arterial pressure began to drop.
infrequent Chain-Stoke's respiration. urinary What immunoglobulins took part in the
retention, slowing-down of heart development of this allergic reaction?
rate, enhancement of spinal reflexes. What A. IgE and IgG
substance caused the poisoning? B. IgG and IgD
A. Atropine C. IgM and IgD
B. Phosphacole D. IgM and IgG
C. Caffeine E. IgA and IgM
D. Morphine 160. A patient suffers from severe
E. Barbital postoperative pseudomonadous infection.
155. Examination of a patient with frequent What of the following antibiotics should be
hemorrhages from internals and mucous administered in this case?
membranes revealed proline and lysine A. Erythromycin
being a part of collagene fibers. What vitamin B. Doxycycline
absence caused disturbance of their C. Cephazolin
hydroxylation? D. Benzylpenicillin
A. Vitamin K E. Amicacin sulfate
B. Vitamin E 161. A patient complains of frequent
C. Vitamin A diarrheas, especially after consumption
D. Vitamin e of fattening food, and of body weight
E. Thiamine loss. Laboratory examination revealed
156. The first grade pupils were examined in steatorrhea: hypocholic feces. What can be
order to sort out children for tuberculosis the cause of this condition?
revaccination. What test was applied for this A. Mucous membrane inflammation of small
purpose? intestine
A. Schick test B. Unbalanced diet

17. C. Lack of pancreatic phospholipase C. Manitole
D. Obturation of biliary tracts D. Clopamide
E. Lack of pancreatic lipase E. Amyloride
162. Having helped to eliminate 167. A newborn child with pylorostenosis
consequences of a failure at a nuclear has often repeating vomiting accompanied
power plant, a worker got an irradiation by apathy, weakness, hypertonicity, sometimes
doze of 500 roentgen. He complains of convulsions. What disorder form of
headache, nausea, dizziness. What changes acid-base balance is it?
in leukocytes quantity can be expected 10 A. Excretory acidosis
hours after irradiation? B. Nongaseous alkalosis
A. Neutrophilic leukocytosis C. Gaseous acidosis
B. Agranulocytosis D. Metabolic acidosis
C. Leukopenia E. Gaseous alkalosis
D. Leukemia 168. After a 2 y.o. child has had flu, there
E. Lymphocytosis appeared complaints about ear ache. A
163. In case of a penetrating wound of the doctor revealed hearing impairment and
anterior abdominal wall the wound tract inflammation of the middle ear. How did
went above the lesser curvature of stomach. the infection penetrate into the middle ear?
What peritoneum formation is most likely A. Through the auditory tube
to be injured? B. Through foramen jugu1aris
A. Ligamentum triangulare sinistrum C. Through canalis caroticus
B. Ligamentum hepatorenale D. Through canalis nasolacrimalis
C. Ligamentum gastrocolicum E. Through atrium mastoideum
D. Ligamentum hepatogastricum 169. In course of an experiment a skeletal
E. Ligamentum hepatoduoduodenale muscle is being stimulated by a series of
164. An electron micrograph of a kidney electric impulses. What type of muscle
fragment presents an afferent arteriole. contraction will arise, if every subsequent
Under its endothelium some big cells can be impulse comes in the period of shortening
seen that contain secretory granules. What of the previous single muscle contraction?
type of cells is it? A. Holotetanus
A. Juxtaglomerular B. Partial tetanus
B. Smooth muscle cells C. A series of single contractions
C. Interstitial D. Muscle contracture
D. Juxtavascular E. Asynchronous tetanus
E. Mesangeal 170. Examination of a miner revealed
165. Arterial pressure of a surgeon who pulmonary fibrosis accompanied by disturbance
performed a long operation rised up to of alveolar ventilation. What is
140/110 mm Hg. What changes of humoral the main mechanism of this disturbance?
regulation could have caused the rise of A. Limitation of respiratory surface of lungs
arterial pressure in this case? B. Constriction of superior respiratory tracts
A. Activation of renin angiotensive system C. Bronchi spasm
B. Activation of sympathoadrenal system D. Disturbance of neural respiration control
C. Inhibition of sympathoadrenal system E. Limitation of breast mobility
D. Activation of formation and excretion of 171. A patient has symptoms of inflammation
aldosterone of urogenital tracts. Examination of a
E. Activation of kallikrein kinin system vaginal smear revealed big monocellular,
166. A patient with chronic cardiac insufficiency pear-shaped organisms with the pointed spike
has been treated with cardiotonic drugs at the posterior end of body, big nucleus
and a thiazide diuretic, but in spite of it there and undulating membrane. What protozoa
are still edemata and risk of ascites. What were found in the smear?
medication should be prescribed to amplify A. Trypanosoma gambiense
diuretic effect of the applied drugs? B. Trichomonas vaginalis
A. Spironolactone C. Trichomonas hominis
B. Furosemide D. Trichomonas buccalis

18. E. Lamblia interstinalis B. Verapamil
172. A child is languid, apathetic. Liver C. Nitroglycerin
is enlarged and liver biopsy revealed a D. Metoprolol
significant excess of glycogene. Glucose E. Propranolol
concentration in the blood stream is below 177. A 63 y.o. man with collapse symptoms
normal. What is the cause of low glucose was delivered to the emergency hospital.
concentration? A doctor chose noradrenaline in order to
A. Deficit of a gene that is responsible prevent hypotension. What is the action
for synthesis of glucose 1-phosphaturidine mechanism of this medication?
transferase A. Activation of dopamine receptors
B. Low (absent) activity of hexokinase B. Block of M -cholinoreceptors
C. High activity of glycogen synthetase C. Activation of serotonin receptors
D. Low (absent) activity of glucose 6- D. Activation of α1-adrenoreceptors
phosphatase E. Activation of β-adrenoreceptors
E. Low (absent) activity of glycogene 178. Urine examination of a patient with
phosphorylase in liver acute cystitis revealed leukocytes and
173. A man who went for a ride on a a lot of gram-negative bacilli. Inoculation
roundabout had amplification of heart rate, resulted in growth of colonies of mucous
sweating and nausea. What receptors stimulation nature that formed green soluble pigment.
is it primarily connected with? What microorganism is the most probable
A. Proprioceptors cause of the disease?
B. Visual A. Proteus mirabilis
C. Auditory B. Escherihia coli
D. Tactors C. Salmonella enteritidis
E. Vestibular D. Klebsiella pneumoniae
174. Two days after consumption of E. Pseudomonas aeruginosa
smoked pork a patient got face and eyelid 179. An isolated cell of human heart
edemata, gastrointestinal disturbances, automatically generates excitation impulses
abrupt temperature rise, muscle pain. Blood with frequency 60 times pro minute. What
analysis showed full-blown eosinophilia. heart structure was this cell obtained from?
What helminth could the patient be infected A. Ventricle
with? B. Atrium
A. Trichina C. Sinoatrial node
B. Hookworm D. Atrioventricular node
C. Whipworm E. His' bundle
D. Ascarid 180. A patient died under conditions of
E. Pinworm cardiovascular insufficiency. Autopsy results:
175. Examination of a patient revealed postinfarction cardiosclcrosis, myocardium
hyperkaliemia and hyponatremia. Low hypertrophy and dilatation of its cavities,
secretion of which hormone may cause such especially of its right ventricle. Liver
changes? is enlarged, its surface is smooth, incision
A. Natriuretic revealed that it was plethoric, with dark-red
B. Parathormone specks against the background of brownish
C. Cortisol tissue. Histologically: plethora of central
D. Aldosteron parts of lobules; peritheral parts around
E. Vasopressin portal tracts contain hepatocytes in a state
176. After a tooth extraction a patient felt of adipose degeneration. How are these liver
persistent pain behind his breast bone. After changes called?
sublingual intake of an antianginal drug the A. Nutmeg liver
pain behind the breast bone disappeared, B. Liver cirrhosis
but the patient complained of headache and C. Liver steatosis
dizziness. What drug are these properties D. Pseudonutmeg liver
typical for? E. Amyloidosis
A. Validol 181. Autopsy of a newborn boy revealed

19. polydactylia, microcephalia, cheiloschisis D. Acute erythromyelosis
and uranoschisis as well as hypertrophy E. Acute myeloblastic leukosis
of parenchimatous organs. These defects 186. Continious taking of a drug can result
correspond with the description of Patau's in osteoporosis. erosion of stomach mucous
syndrome. What is the most probable cause membrane, hypokaliemia, retention of sodium
of this pathology? and water, reduced content of corticotropin
A. Trisomy of the 18th chromosome in blood. Name this drug:
B. Trisomy of the 21st chromosome A. Digoxin
C. Trisomy of the 13th chromosome B. Indometacin
D. Nondisjunction of sex chromosomes C. Reserpine
E. Partial monosomy D. Prednisolone
182. Glutamate decarboxylation results in E. Hydrochlorothiazide
formation of inhibitory transmitter in CNS. 187. A patient has a haemorrhage into the
Name it: posterior central gyrus. What type of sensitivity
A. Serotonin on the opposite side will be disturbed?
B. Histamine A. Visual
C. Glutathione B. Auditory and visual
D. Asparagine C. Auditory
E. GABA D. Olfactory
183. A patient who suffers from acute E. Skin and proprioceptive
myocarditis has clinical signs of cardiogenic 188. As a result of an accident a patient
shock. What of the under-mentioned has intense painfullness and edema of the
pathogenetic mechanisms plays the main anterior crus surface: dorsal f1exion of foot
part in shock development? is hindered. Function of which crus muscle
A. Disturbance of pumping ability of heart is most likely to be disturbed?
B. Depositing of blood in organs A. M.peroneus longus
C. Reduction of diastolic flow to the heart B. M.flexor digitorum longus
D. Decrease of vascular tone C. M.flexor hallucis longus
E. Increase of peripheral vascular resistance D. M.peroneus brevis
184. A patient who has been treated E. M.tibialis anterior
with diazepam on account of neurosis 189. A 2 y.o. child has convulsions as a result
complains of toothache. Doctor administered of lowered concentration of calcium ions in
him an analgetic, but its dose was lower than blood plasma. It is caused by reduced function
average therapeutic dose. What of:
phenomenon did the doctor take into A. Adrenal cortex
account while prescribing the patient an B. Pineal gland
underdose? C. Hypophysis
A. Summation D. Parathyroid glands
B. Potentiation E. Thymus
C. Cumulation 190. Histological specimen presents a vessel
D. Tolerance the wall of which consists of endothelium,
E. Drug dependence basal membrane and loose connective tissue.
185. A 23 y.o. patient complains of What type of vessel is it?
weakness, temperature rise up to 38-40°C. A. Hemocapillary
Objectively: liver and spleen are enlarged. B. Lymphocapillary
Hemogram: Hb- 100 g/L erythrocytes - C. Vein of non-muscular type
2.9*1012/l, leukocvtes - 4.4· l09/l, thrombocytes D. Vein of muscular type
- 48*109 /1, segmentonuclear neutrophils 17% E. Artery
lymphocytes - 15%, blast cells - 68%. 191. Examination of a man who hadn't been
All cytochemical reactions are negative. consuming fats but had been getting enough
Make a hematological conclusion: carbohydrates and proteins for a long time
A. Undifferentiated leukosis revealed dermatitis, poor wound healing, vision
B. Acute lymphoblastic leukosis impairment. What is the probable cause
C. Chronic myeloleukosis of metabolic disorder?

20. A. Low caloric value of diet necrosis, fibrinous thrombs in their lumens;
B. Lack of vitamins PP, H sclerosis and hyalinosis of glomerules,
C. Lack of palmitic acid atrophy of tubules and fibrosis of renal
D. Lack of linoleic acid, vitamins A, D, E, K stroma. What is the most probable diagnosis?
E. Lack of oleic acid A. Membranous nephropathy
192. Analysis of a punction biopsy material B. Acute glomerulonephritis
of liver revealed hepatocyte dystrophy with C. Focal segmentary sclerosis
necroses as well as sclerosis with disorder of D. Subacute glomerulonephritis
beam and lobulous structure, with formation E. Chronic glomerulonephritis
of pseudolobules and regenerative nodes. 197. To prevent postoperative bleeding
What is the most probable diagnosis: a 6 y.o. child was administered vicasol
A. Acute hepatitis that is a synthetic analogue of vitamin K.
B. Progressive massive liver necrosis Name post-translational changes of blood
C. Liver cirrhosis coagulation factors that will be activated by
D. Chronic hepatosis vicasol:
E. Chronic hepatitis A. Phosphorylation of serine radicals
193. A 50 y.o. patient was admitted to the B. Polymerization
hospital with complaints about pain behind C. Partial proteolysis
his breastbone, asphyxia during physical D. Glycosyiation
activity. Angiography revealed pathological E. Carboxylation of glutamin acid
changes in the posterior interventricular 198. According to clinical indications a patient
branch of the right eoronary artery. What was administered pyridoxal phosphate.
heart parts are affected? What processes is this medication intended
A. Posterior wall of the right and left ventricles to correct?
B. Right atrioventricular valve A. Oxidative decarboxylation of ketonic
C. Right atrium acids
D. Left atrium B. Transamination and decarboxylation of
E. Anterior wall of the right and left ventricles aminoacids
194. A hepatitis outbreak was registered in C. Desamination of purine nucleotide
a settlement. This episode is connected with D. Synthesis of purine and pyrimidine bases
water factor. What hepatitis virus could E. Protein synthesis
have caused the infective outbreak in this 199. A 62 y.o. woman complains of
settlement? frequent pains in the area of her chest and
A.E backbone, rib fractures. A doctor assumed
B.C myelomatosis (plasmocytoma). What of the
C.B following laboratory characteristics will be
D.D of the greatest diagnostical importance?
E.G A. Hyperalbuminemia
195. Examination of coronary arteries B. Proteinuria
revealed atherosclerotic calcific plaques that C. Hypoglobulinemia
close vessel lumen by 1/3. The muscle has D. Paraproteinemia
multiple whitish layers of connective tissue. E. Hypoproteinemia
What process was revealed in myocardium? 200. A hypertensive glucose solution was
A. Postinfarction cardiosclerosis introduced to a patient. It will intensify
B. Tiger heart water movement:
C. Myocardium infarction A. From the capillaries to the intercellular
D. Myocarditis liquid
E. Diffuse cardiosclerosis B. There will be no changes of water
196. Microscopical renal examination of a movement
36 y.o. woman who died from renal insufficiency C. From the intercellular liquid to the cells
revealed in the glomerules proliferation D. From the cells to the intercellular liquid
of capsule nephrothelium as well as E. From the intercellular liquid to the capillaries.
of podocytes and phagocytes accompanied
by formation of "crescents", capillary loop