1. The document discusses various medical cases and questions. It includes a case of glaucoma where the increased intraocular tension is due to injury of the ciliary muscle. 2. Another case involves a woman diagnosed with Bartholinitis, which is inflammation of the Bartholin's glands located in the labia minora. 3. Multiple choice questions cover topics like cardiac function, genetic disorders, anatomy, pathology, and pharmacology. The document contains medical information and questions to test one's knowledge of various body systems and diseases.

1. 1. The increased intraocular tension 6. A 32-year-old patient has been diagnosed
is observed in a patient with glaucoma. with bartholinitis (inflammation
Secretion of aqueous humor by the ciliar of Bartholin's glands ). In what part of the
body is normal. Injury of what structure of female urogenital system are the Bartholin's
the eyeball caused the disorder of flow-out glands located?
from 'the anterior chamber? A. The vagina
A. Back epithelium of cornea B. The uterus
B. Choroid C. The labia minor
C. Ciliary muscle D. The clitoris
D. Venous sinus E. The labia major
E. Ciliar body 7. The calcium canals of cardiomyocytes
2. A patient visited a dentist with complaints have been blocked on an isolated rabbit's
of redness and edema of his mouth heart. What changes in the heart's activity
mucous membrane in a month after dental can happen as a result?
prosthesis. The patient was diagnosed with A. Decreased rate and force of heart beat
allergic stomatitis. What type of allergic B. Heart stops in systole
reaction by Gell and Cumbs underlies this C. Decreased force of the contraction
disease? . D. Decreased heart beat rate
A. Cytotoxic E. Heart stops in diastole
B. Immunocomplex 8. Substitution of the glutamic acid on
C. Anaphylactic valine was revealed while examining initial
D. Delayed type hypersensitivity molecular structure. For what inherited
E. Stimulating pathology is this symptom typical?
3. An autopsy revealed large (1-2 cm) A. Thalassemia
brownish-red, easy crumbling formations B. Sickle-cell anemia
covering ulcerative defects on the external C. Favism
surface of the aortic valve. What is the most D. Minkowsky-Shauffard disease
likely diagnosis? E. Hemoglobinosis
A. Diffusive endocarditis 9. A patient has undergone an amputation
B. Polypus-ulcerative endocarditis of lower extremity. Some time later painful
C. Fibroplastic endocarditis nodules appeared in a stump. Amputatious
D. Acute warty endocarditis neuromas were found out at the microscopic
E. Recurrent warty endocarditis examination. To what pathological
4. A patient with suspicion on epidemic processes do those formations relate?
typhus was admitted to the hospital. Some A. Metaplasia
arachnids and insects have been found in B. Inflammation
his flat. Which of them may be a carrier of C. Regeneration
the pathogen of epidemic typhus? D. Dystrophy
A. Bed-bugs E. Hyperemia
B. Houseflies 10. A patient with injured muscles of
C. Lice the lower extremities was admitted to
D. Spiders the traumatological department. Due to
E. Cockroaches what cells is reparative regeneration of the
5. A 27- year-old woman has used penicillin muscle fibers and restoration of the muscle
containing eye drops. In a few minutes itching, function possible?
skin burning. lips and eyelids edema. A. Satellite-cells
whistling cough. decreasing BP appeared. B. Fibroblasts
What antibodies can lead to this allergic C. Myoepithelial cells
reaction? D. Myoblasts
A. IgE and IgG E. Myofibroblasts
B. IgM and IgD 11. A worker has decreased buffer capacity
Co IgA and IgM of blood due to exhausting muscular work
D. IgG and IgD The influx of what acid substance in the
E. IgM and IgG blood can cause this symptom?

2. A.3-phosphoglycerate the bars form three zones. Medulla consists
B.l,3-bisphosphoglycerate of chromaffinocytes and venous sinusoids.
C. Pyruvate Which organ has these morphological
D. α-ketoglutarate features?
E. Lactate A. Thyroid
12. A 63-year-old woman developed B. Lymph node
symptoms of rheumatoid arthritis. Their C. Kidney
increase of which blood values indicators D. Adrenal gland
could be the most significant in proving the E. Thymus
diagnosis? 17. The study of the genealogy of a family
A. Additive glycosaminoglycans with hypertrichosis (helix excessive pilosis)
B. Acid phosphatase has demonstrated that this symptom
C. Lipoproteids is manifested in all generations only in men
D. General cholesterol and is inherited by son from his father. What
E. R-glycosidase is the type of hypertrichosis inheritance?
13. A 50-year-old man has felt vague A. Y-linked chromosome
abdominal discomfort within past 4 B. Autosome-dominant
months. Physical examination revealed C. Autosome-recessive
no lymphadenopathy, and no abdominal D. X-linked dominant chromosome
masses or organomegaly at palpation. E. X-linked recessive chromosome
Bowel sounds are heard. An abdominal CT 18. Succinate dehydrogenase catalyses the
scan shows a 20 cm retroperitoneal soft tissue dehydrogenation of succinate. Malonic acid
mass obscuring the left psoas muscle. HOOC-CH2-COOH is used to interrupt
A stool specimen tested for occult blood is the action of this enzyme. Choose the inhibition
negative. Which of the following neoplasms type:
is this man most likely to have? A. Non-competitive
A. Adenocarcinoma B. Limited proteolysis
B. Lymphoma C. Allosteric
C. Lipoma D. Competitive
D. Melanoma E. Dephosphorylation
E. Hamartoma 19. A patient has a malignisation of thoracic
14. The penetration of the irritable cell part of esophagus. What lymphatic nodes
membrane for potassium ions has been are regional for this organ?
increased during an experiment. What A. Nodi lymphatici mediastinales posteriores
changes of membrane electric status can B. Nodi lymphatici paratrachealis
occur? C. Nodi lymphatici prevertebralis
A. Action potential D. Nodi lymphatici pericardiales laterales
B. Depolarization E. Anulus lymphaticus cardiae
C. Hyperpolarization 20. A patient with bronchial asthma had
D. No changes been taking tablets which caused insomnia,
E. Local response headache, increased blood pressure. What
15. Examination of a person revealed that medecine can cause such complications?
minute volume of heart is 3500 mL, systolic A. Ephedrine
volume is 50 mL. What is the frequency of B. Chromolin sodium
cardiac contraction? C. Euphyline
A. 50bpm D. Adrenaline
B. 70bpm E. Izadrine
C. 80bpm 21. Inhibition of alpha-motoneuron of the
D. 60bpm extensor muscles was noticed after stimulation
E. 90bpm of a-motoneuron of the flexor
16. A histological spacemen presents muscles during the experiment on the spinal
parenchymal organ, which has cortex and column. What type of inhibition can be
medulla. Cortex consists of epitheliocytes caused by this process?
bars with blood capillaries between them; A. Depolarizational

3. B. Reciprocal C. In the collecting duck
C. Lateral D. In distal tubule of nephron
D. Presynaptic E. In proximal tubule of nephron
E. Recurrent 27. A patient suffering from trombophlebitis
22. During histological examination of the of deep veins suddenly died. The autopsy
stomach it was found out that glands contained has shown freely lying red friable masses
very small amount of pariental cells or with dim crimped surface in the trunk and
they were totally absent. Mucose membrane bifurcation of the pulmonary artery. What
of what part of the stomach was studied') pathologic process was revealed by the
A. - morbid anatomist?
B. Cardia A. Tissue embolism
C. Body of stomach B. Fat embolism
D. Pyloric part C. Tromboembolism
E. Fundus of stomach D. Thrombosis
23. A businessman came to India from E. Embolism with foreign body
South America. On examination the physician 28. On autopsy of a still-born infant
found that the patient was suffering abnormalities have been revealed: ventricles
from sleeping-sickness. What was the way are not separated, a single arterial trunk
of invasion? originates from the right part. For what class
A. After contact with a sick dogs of vertebrates is such heart construction
B. Through dirty hands characteristic?
C. As a result of mosquito's bites A. Fishes
D. With contaminated fruits and vegetables B. Birds
E. As a result of bug's bites C. Amphibian
24. A patient has been taking a mixture D. Reptiles
prescribed by neuropathologist for E. Mammals
neurasthenia for two weeks. The patient 29. A man after 1,5 litre blood loss has
feels better but has developed coryza, suddenly reduced diuresis. TIle increased
conjunctivitis, rash, inertia, decrease of secretion of what hormone caused such diuresis
memory. She is diagnosed with bromizm. alteration?
What should be prescribed to decrease the A. Parathormone
symptoms? B. Corticotropin
A. Glucose solution 5% C. Vasopressin
B. Polyglucin D. Cortisol
C. Asparcam E. Natriuretic
D. Natrium chloride 30. Blood analysis of a patient showed signs
E. - of HIV infection (human immunodeficiency
25. When the pH level of the stomach lumen virus). Which cells does HIV-virus primarily
decreases to less than 3, the antrum of affect?
the stomach releases peptide that acts in A. Specialized nervous cells (neurons)
paracrine fashion to inhibit gastrin release. B. Cells that contain receptor IgM (B-
This peptide is: lymphocytes)
A. Gastrin-releasing peptide (GRP) C. Cells that contain receptor T4 (T-helpers)
B. GIF D. Proliferating cells (stem hematoplastic
C. Somatostatin cells)
D. Vasoactive intestinal peptide (VIP) E. Mast cells
E. Acetylcholine 31. Slime, blood and protozoa 30-200 microns
26. The low specific gravity of the secondary of length have been revealed in a
urine (1002) was found out in the sick man's feces. The body is covered with cilias
person. What is the most distant part of and has correct oval form with a little bit
nephron where concentration of secondary narrowed forward and wide round shaped
urine takes place? back end. On the forward end a mouth is visible.
A. In the nephron's glomerulus In cytoplasm there are two nucleuses
B. In ascending part of loop of Henle

4. and two short vacuoles. For whom are the degrees due to gamma radiation. What type
described attributes typical? of mutation took place in the DNA chain'?
A. Balantidium A. Replication
B. Trichomonas B. Inversion
C. Intestinal amoeba C. Translocation
D. Dysenteric amoeba D. Doubling
E. Lamblia E. Deletion
32. A doctor administered Allopurinol to a 38. Periodic renal colics attacks are
26-year-old young man with the symptoms observed in a woman with primer!
of gout. What pharmacological action of hyperparathyroidizm. Ultrasonic examination
Allopurinol ensures therapeutical effect? revealed small stones in the kidneys.
A. By increasing uric acid excretion What is the most plausible reason of the
B. By inhibiting leucocyte migration into the stones's formation?
joint A. Hyperphosphatemia
C. By inhibiting uric acid synthesis B. Hyperuricemia
D. By general analgetic effect C. Hypercalcemia
E. By general anti-inflammatory effect D. Hyperkalemia
33. A person has steady HR not exceeding E. Hypercholesterinemia
40 bpm. What is the pacemaker of the heart 39. The gluconeogenesis is activated in the
rhythm in this person? liver after intensive physical trainings .What
A. Atrioventricular node substance is utilized in gluconeogenesis first
B. His' bundle of all in this case:
C. Sinoatrial node A. Glutamate
D. Purkinye' libel'S B. Pyruvate
E. Branches of His' bundle C. Lactate
34. In the ovary specimen colored with D. Glucose
hematoxylin-eosin, follicle is determined E. Alanine
where cubic-shaped follicle epithelium cells 40. From the nasopharynx of a 5-year-
are placed in 1-2 layers, and scarlet covering old child 3 microorganism was excreted
is seen around ovocyte. Name this follicle: which is identical to Corynebacterium diphtheriae
A. Primordial dose according to morphological
B. Secondary and biochemical signs. Microorganism does
C. Mature . not produce exotoxin. As a result of what
D. Atretic process can this microorganism become
E. Primary toxigenic?
35. A denaturation of proteins can be found A. Phage conversion
in some substances. Specify the substance B. Passing through the organism of the
that is used for the incomplete denaturation sensative animals
of hemoglobin: C. Chromosome mutation
A. Toluene D. Growing with antitoxic serum
B. Sulfuric acid E. Cultivation in the telluric environment
C. Nitric acid 41. Necrosis focus was observed in the area
D. Urea of hyperemia. and skin edema in a few hours
E. Sodium hydroxide after burn. What mechanism strengthens
36. Ovarian tumour was diagnozed in a destructive effects in the inftamn1ation
woman. Surgery should be perfomed. What area?
ligament should be extracted by the surgeon A. Primary alteration
to disconnect the ovary and the uterus? B. Emigration of lymphocytes
A. Lateral umbilical ligament C. Diapedesis of erythrocytes
B. Suspensory ligament of ovary D. Proliferation of fibroblasts
C. The ovarial ligament E. Secondary alteration
D. Round ligament of uterus 42. There is an inhibited coagulation in the
E. Broad ligament of uterus patients with bile ducts obstruction, bleeding
37. Part of the DNA chain turned about 180 due to the low level of absorbtion of a

5. vitamin. What vitamin is in deficiency? B. Escherichia
A. Carotene C. Shigell
B. E D. Streptococcus
C. K E. Staphylococcus
D. A 48. A 58-year-old female has undergone
E. D surgery for necrotic bowel. Despite having
43. In case of enterobiasis acrihine - the been treated with antibiotics, on
structural analogue of vitamin B2 - is postoperative day 5, she develops symptoms
administered. (fever, hypotension, tachycardia, declining
The synthesis disorder of which urine output, and confusion) consistent with
enzymes does this medicine cause in septic shock. What hemodynamic support
microorganisms? would be helpful?
A. NAD-dependet dehydrogenases A. Fluid administration
B. Cytochromeoxidases B. Dobutamine infusion
C. Aminotransferases C. Fluids and Dobutamine infusion
D. Peptidases D. Atropine administration
E. FAD-dependent dehydrogenases E. Antibiotic administration
44. A patient with hypochromic anemia 49. A man died 8 days after the beginning
has splitting and loss of hair, increased nail of the disease. He was diagnosed with
brittling and taste alteration. What IS the dysentery. At the autopsy it was found
mechanism of the symptoms development? out 'a thickened wall of the sigma and
A. Decreased production of parathyrin rectum. fibrinous membrane on the surface
B. Deficiency of vitamin A of mucous membrane. Histologically: there
C. Deficiency of iron-containing enzymes is a deep necrosis of mucous membrane with
D. Decreased production of thyroid infiltration of necrotic masses with fibrin.
hormones What kind of colitis does correspond to the
E. Deficiency of vitamin B12 changes?
45. Blood sampling for bulk analysis is A. Catarrhal
recommended to be performed on an B. Diphtheritic
empty stomack and in the morning. What C. Ulcerative
changes in blood composition can occur if to D. Chronic
perform blood sampling after food intake? E. Gangrenous
A. Increased plasma proteins 50. The electronic microphoto of kidney
B. Increased contents of leukocytes fragment has exposed afferent glomerular
C. Reduced contents of erythrocytes arteriole, which has giant cells under its
D. Increased contents of erythrocytes endothelium, containing secretory granules.
E. Reduced contents of thrombocytes Name the type of these cells:
46. The high level of Lactate Dehydrogenase A. Interstitial
(LDH) isozymes concentration showed the B. Mesangial
increase of LDH-l and LDH-2 in a patient's C. Smoothmuscular
blood plasma. Point out the most probable D. Juxtavascular
diagnosis: E. Juxtaglomerular
A. Myocardial infarction 51. When a patient with traumatic impairment
B. Acute pancreatitis of the brain was examined, it was discovered
C. Skeletal muscle dystrophy that he had stopped to distinguish
D. Viral hepatitis displacement of an object on the skin. What
E. Diabetes mellitus part of the brain was damaged?
47. Red colonies spread in the large quantity A. Posterior central gurus
in the Endo culture medium were revealed B. Frontal zone
on bacteriological stool examination of a 4month- C. Frontal central gurus
old baby with the symptoms of acute D. Parietal zone of the cortex
bowel infection. What microorganism can it E. Occipital zone of the cortex
be? 52. A 30-year-old patient was hospitalized
A. Salmonella due to bleeding of the facial artery. What

6. place on the face has to be pressed to stop by what of the following cells is the most
bleeding? typical for the process occuring here?
A. The mandible's branch A. Monocytes
B. The nose's back B. Limphocytes
C. The molar bone C. Neutrophils
D. The mental process D. Eosinophils
E. The mandible's edge E. Basophils
53. A patient with complaints of 3-day-long 58. Marked increase of activity of MB-forms
fever, general weakness, loss of appetite of CPK (creatinephosphokinase) and
came to visit the infectionist. The doctor LDH-l was revealed by examination of the
suspected enteric fever. Which method of patient's blood. What is the most probab1e
laboratory diagnosis is the best to confirm pathology?
the diagnosis? A. Rheumatism
A. Detachment of myeloculture B. Hepatitis
B. Detachment of urine culture C. Miocardial infarction
C. Detachment of feces culture D. Pancreatitis
D. Detachment of blood culture E. Cholecystitis
E. Detachment of pure culture 59. A patient who came to the doctor
54. A 50-year-old patient with typhoid fever because of his infertility was administered
was treated with Levomycetin, the next day to make tests for toxoplasmosis and chronic
his condition became worse, temperature gonorrhoea. Which reaction should be
rose to 39,6°. What caused the complication? performed to reveal latent toxoplasmosis
A. Secondary infection addition and chronic gonurrhoea of the patient?
B. Irresponsiveness of an agent to the A. IFA .. Immunofluorescence assay
levomycetin B. RIHA - Reverse indirect hemagglutination
C. The effect of endotoxin agent assay
D. Allergic reaction C. (R)CFT- Reiter's complement fixation
E. Reinfection test
55. A student is thoroughly summarising a D. RDHA - Reverse direct hemagglutination
lecture. When his groupmates begin talking assay
the quality of the summarising worsens E, Immunoblot analysis
greatly. What type of inhibition in the 60. A 45-year-old woman suffers from
cerebral cortex is the cause of it? allergic seasonal COr'/Z2 caused by the
A. Differential ambrosia blossoming. What adipose cells
B. Dying group stabilizer medicine can be used for
C. Protective prevention of this disease?
D. External A. Phencarol
E. Delayed B. Diazoline
56. A 46 year-old man complains of difficult C. Ketotifen
nose breathing. Mikulich cells, storage of D. Dimedrol
epithelioid cells, plasmocytes, lymphocytes. E. Tavegyl
hyaline balls are discovered in the biopsy 61. A patient after pathological process has
material of the nose thickening. What is the a thickened alveolar membrane. The direct
most likely diagnosis? consequence of the process will be the
A. Virus rhinitis reduction of:
B. Rhinovirus infection A. Reserve expiratiory capacity
C. Meningococcal nasopharyngitis B. Minute respiratory capacity
D. Allergic rhinitis C. Alveolar lung ventilation
E. Scleroma Do Oxygen capacity of blood
57. A 16-year-old boy was performed an E. Diffuse lung capacity
appendectomy. He has been hospitalized 62. A 59-year-old man has symptoms
for right lower quadrant abdominal pain of parenchymatous jaundice and portal
within 18 hours. The surgical specimen is hypertension. Histological examination
edematous and erythematous. Infiltration of the puncture of the liver bioptate

7. has revealed an affected beam-lobule blood pressure. Increasing of the osmotic
structure, part of hepatocytes has signs of concentration and dispersity of protein
fat dystrophy, port-portal connective tissue structures can be found in the intercellular
septa with formation of pseudo-lobules, with fluid. What kind of edema are to be
periportal lympho-macrophage infiltrations. observed in this case?
What is the most probable diagnosis? A. Lymphogenic
A. Liver cirrhosis B. Mixed
B. Alcohol hepatitis C. Colloid-osmotic
C. Toxic dystrophy D. Membranogenic
D. Chronic hepatosis E. Hydrodynamic
E. Viral hepatitis 68. A patient died from acute cardiac
63. The preventive radioprotector was given insufficiency. The histological examination
to a worker of a nuclear power station. of his heart revealed the necrotized section
What mechanism from the below mentioned in myocardium of the left ventricle, which
is considered to be the main mechanism was separated from undamaged tissue
of radioprotection? by the zone of hyperimic vessels, small
A. Activation of oxidation reactions hemorrhages and leukocytic infiltration.
B. Prevention of tissue's hypoxia What is the most likely diagnosis?
C. Increasing of tissue blood supply A. Myocardial infarction
D. Inhibition of free radicals formation B. Myocardial ischemic dystrophy
E. Increasing of respiration C. Productive myocarditis
64. After the trauma. the patient's right D. Focal exudate myocarditis
n.vagus was damaged. Which violation of E. Diffuse exudate myocarditis
the cardiac activity is possible in this case? 69. A 56-year-old patient complaining of
A. Violation of a conductivity in the right thirst and frequent urination was diagnosed
auricle with diabete mellitus. Butamin was prescribed.
B. Violation of the automatism of a How does the medicine act?
atrioventricular A. It inhibits α-cells of Langergans' islets
node B. It inhibits absorption of glucose in the
C. Block of a conductivity in the atrioventricular intestines
node C. It relieves transport of glucose through
D. Violation of the automatism of a Kiss-Fleck the cells' membranes
node D. It stimulates β-cells of Langergans' islets
E. Arrhythmia E. It helps to absorb the glucose by the cells
65. A highly injured person has gradually died. of the organism tissues
Please choose the indicator of biological 70. Galactosemia has been revealed in
death: a child. Concentration of glucose in the
A. Disarray of chemical processes blood has not considerably changed. What
B. Autolysis and decay in the cells enzyme deficiency caused this illness?
C. Absence of palpitation and breathing A. Galactokinase
D. Absence of movements B. Galactose-1-phosphate uridyltransferase
E. Loss of consciousness C. Hexokinase
66. During the experiment on the influence D. Amylo-1,6-glucosidase
of chemical substances in the muscles the E. Phosphoglucomutase
reaction of Ca2+ - pump is weakened. Which 71. During the endoscopy the inflammation
phenomenum will be observed? of a major papilla of the duodenum
A. Prolonged duration of the AP and the disturbances of bile secretion were
B. Decreased AP found. In which part of duodenum were the
C. Prolonged relaxation problems found?
D. Decreased velocity of the AP distribution A. Lower horizontal part
E. Activation of the sodium-potassium pump B. Ascendant part
67. Inflamation is characterised by increasing C. Descendent part
penetration of vessels of microcirculation D. Upper horizontal part
stream, increasing of their fluid dynamic E. Bulb

8. 72. A 37-year-old man was admitted and small-grained. Microscopically:
to the surgical department with the fibrinogenous
symptoms of acute pancreatitis: vomiting, inflammation of serous and
diarrhea, bradycardia, hypotention, mucous capsules, dystrophic changes of
weakness, dehydration of the organism. parenchymatous organs, brain edema. What
What medicine should be used first of all? complication can cause such changes of
A. Ephedrine serous capsules and inner organs?
B. Platyphylline A. Sepsis
C. No-spa B. Uraemia
D. Etaperazine C. Thrombopenia
E. Contrycal D. DIC-syndrome
73. Hydroxylation of endogenous substrates E. Anemia
and xenobiotics requires a donor of protons. 78. A 13-year-old girl with history of
Which of the following vitamins can play asthma complained of cough, dyspnea
this role? and wheezing. Her symptoms became so
A. Vitamin B6 severe that her parents brought her to
B. Vitamin A the emergency room. Physical examination
C. Vitamin P revealed diaphoresis, dyspnea, tachycardia
D. Vitamin C and tachypnea. Her respiratory rate was
E. Vitamin E 42/min. pulse rate was 110 beats per minute,
74. Obturative jaundice developed in a and blood pressure was l30/70 mm
60-year-old patient because of malignant Hg. Choose from the following list the
tumour of the big papillary of the duodenal. most appropriate drug to reverse the
Lumen of what anatomical structure is bronchoconstriction rapidly:
squeezed with tumour? A. Methylprednidsolone
A. Right hepatic duct B. Salbutamol
B. Common hepatic duct C. Beclomethasone
C. Hepatopancreatic ampulla D. Cromolyn
D. Cystic duct E. Ipratropium
E. Left hepatic duct 79. Chronic glomerulonephritis was diagnosed
75. A couple came for medical genetic in a 34-year-old patient 3 years
counseling. The man has hemophilia, the ago. Edema has developed within the last
woman is healthy and there were no cases 6 monthes. What caused the edema?
of hemophilia in her family. What is the risk A. Hyperosmolarity of plasma
of having a sick child in this family? B. Hyperaldosteronism
A.O C. Liver disfunction of protein formation
B.25% D. Hyperproduction of vasopressin
C.50% E. Proteinuria
D.I00% 80. An isolated muscle of a frog is rhythmically
E. 75% irritated with electric impulses. Every
76. Different functional groups can be next impulse is in a period of relaxation
presented in the structure of L-amino acid's from the previus contraction. What
radicals. Identify the group that is able contraction of the muscle occurs?
to form ester bond: A. Continuous (smooth) tetanus
A. -CH3 B. Asynchronous
B.-CONH2 C. Single
C.-OH D. Waved tetanus
D. -NH2 E. Tonic
E.-SH 81. The CNS stimulation produced by
77. For a long time a 49-year-old woman methylxanthines, such as caffeine, is most
had suffered from glomerulonephritis which likely due to the antagonism of one of the
caused death. The autopsy revealed following recertors:
that the size of her kidneys was 7x3x2,5 A. Glycine receptors
sm, weight 65,0 g, they were dense B. Adenosine receptors

9. C. Glutamate receptors injured?
D. GABA receptors A. The mind-brain
E. Cholinergic muscarinic receptors B. The medulla oblongata
82. During complicated labour the C. The cerebellum
symphysis pubis ruptured. What organ can D. The inter-brain
be damaged mostly? E. The spinal cord
A. Uterus 87. The alveolar ventilation of the patient is
B. Rectum 5 L/min, the breath frequency is 10 per/min,
C. Ovaria and the tidal volume is 700 ml. What is the
D. Urinary blader patient's dead space ventilation?
E. Uterine tubes A. 2,0 L/min
83. A patient with abscess of the cut B. 4,3 L/min
wound applied to the traumatological c.-
department. The wound was washed with D. 0,7 L/min
3% hydrogen peroxide to be cleaned from E. 1,0 L/min
the pus. Foam was not observed. What 88. An old woman was hospitalized with
caused inefficiency of the drug? acute pain, edema in the right hip joint; the
A. Pus in the wound movements in the joint are limited. Which
B. Shallow wound bone or part of it was broken?
C. Inherited insufficiency of catalase A. Pubic bone
D. Low concentration H202 B. The neck of the thigh
E. Inherited insufficiency erythrocyte's C. Condyle of the thigh
phosphatdehydrogenase D. Ischial bone
84. A woman suffering from dysfunctional E. The body of the thigh bone
metrorrhagia was made a diagnostic abortion. 89. A patient, who suffers from congenital
Histologically in the scrape there were erythropoietic porphyria, has skin
a lot of small stamped glandulars covered photosensitivity. The accumulation of what
with multirowed epithelium. The lumens of compound in the skin can cause it?
some glandulars were cystically extended. A. Heme
Choose the variant of general pathologic B. Uroporphyrinogen 2
process in the endometrium. C. Coproporphyrinogen 3
A. Glandular-cystic hyperplasia of D. Protoporphyrin
endometrium E. Uroporphyrinogen 1
B. Neoplasm of endometrium 90. A patient died 3 days after the operation
C. Atrophy of endometrium because of perforated colon with manifestations
D. Metaplasia of endometrium of diffuse purulent peritonitis.
E. Hypertrophic growth The autopsy revealed: colon mucos
85. An autopsy revealed: soft arachnoid membrane was thickened and covered with
membrane of the upper parts of cerebral a fibrin film, isolated ulcers penetrated at
hemisphere is plethoric, of yellowish-green different
color, soaked with purulent and fibrose depth. The histology result: mucous
exudate, it lookes like a cap. What disease is membrane necrosis, leukocytes infiltration
characterised by these symtoms? with hemorrhages focuses. What disease
A. Tuberculous meningitis complication caused the patient's death?
B. Meningitis at typhus A. Dysentery
C. Influenza meningitis B. Crohn's disease
D. Meningitis at anthrax C. Amebiasis
E. Meningococcal meningitis D. Typhoid
86. A 50 year-old patien was injured on E. Nonspecific ulcerative colitis
the occipital region of the head. The closed 91. The formation of a secondary mediator
skull's trauma was diagnosed. She was taken is obligatory in membrane-intracellular
to the hospital. The medical examination: mechanism of hormone action. Point out
deregulation of walking and balance. the substance that is unable to be a
trembling of arms. What part of brain was secondary mediator:

10. A. Glycerol B. Anconeus muscle
B. Diacylglycerol C. Tendon of the triceps muscle
C. CAMP D. Aponeurosis of biceps muscle
D. CA2+ E. Brachioradial muscle '
E. Inositol-3,4,5-triphosphate 97. The reason of occurrence of some diseases
92. A 45-year-old man with domestic apper of an oral cavity is connected with
arm injuiry came to the trauma unit. The structural peculiarities of its mucous
objective data are: there are no extension, membrane. What morphological attributes
adduction or pronation functions of characterize these features?
the arm. What muscle damage caused this A. Transitional epithelium, no submucosa
condition? B. No muscularis mucosa, stratified
A. Subscapular squamous epithelium
B. Teres major C. Transitional epithelium, no muscularis
C. Subspinous mucosa
D. Supraspinous D. Simple columnar ciliated epithelium
E. Teres minor E. Well developed muscularis, no submucosa
93. The conjugated protein necessarily 98. A journalist's body temperature
contains special component as a nonprotein has sharply increased in the morning
part. Choose the substance that three weeks after his mission in India,
can't carry out this function: it was accompanied with shivering and
A. Thiamine pyrophosphate bad headache. A few hours later the
B. Glucose temperature decreased. The attacks began
C. HN03 to repeat in a day. He was diagnosed
D. AMP with tropical malaria. What stage of
E. ATP development of Plasmodium is infective for
94. M-r S presents all signs of the hepatic anopheles-female?
coma: loss of consciousness, absence of A. Merozoites
reflexes, cramps, convulsion, disorder of B. Gametocytes
heart activity, recurrent (periodical) respiration. C. Sporozoites
What are cerebrotoxical substances D. Microgamete
which accumulate in blood under hepar E. Shizontes
insufficiency? 99. A sick man with high temperature and
A. Autoantibody a lot of tiny wounds on the body has been
B. IL-l admitted to the hospital. Lice have been
C. Necrosogenic substances found in the folds of his clothing. What disease
D. Ammonia can be suspected in the patient?
E. Ketonic body A. Plague
95. A 60-year-old patient was hospitalised B. Scabies
to the surgical department because c. Malaria
of infection caused by blue pus bacillus D. Epidemic typhus
(Pseudomonas aeruginosa) which is sensative E. Tularemia
to penicillin antibiotics. Indicate which of 100. The sterile Petri dishes and pipettes
the given penicillins has marked activity to are necessary to prepare for microbiological
the Pseudomonas aeruginosa? tests in bacteriological laboratory. What
A. Oxacillin way of sterilization should be applied in this
B. Benzylpenicillin case?
C. Methicillin A. Dry-heat sterilization
D. Phenoxymethylpenicillin B. Boiling
E. Carbenicillin disodium C. Pasteurization
96. Usually the intravenous injection is done D. Tyndallization
into median cubital vein because it is slightly E. Steam sterilizntion in autoclave
movable due to fixation by the soft 101. An intraoperational biopsy of mammal
tissues. What does it fix in the cubital fossa? gland has revealed the signs of atypical tissue
A. Brachial muscle with disorder of parenchyma stroma

11. proportion with domination of the last, E. Increased pressure in Bowman's capsule
gland structures of different size and shape, 106. If strong oxidizers get into the
lined with single-layer proliferative epithelium. bloodstream. a methemoglobin is formed.
What is the most probable diagnosis? It is a compound, where iron (II) becomes
A. Fibroadenoma iron (III). What has to be done to save the
B. Papilloma patient?
C. Noninfiltrative cancer A. He has to be calmed down and put to bed
D. Mastitis B. Interchangeable hemotransfusion has to
E. Infiltrative cancer be done
102. A 10-year-old child complains of C. He has to be given pure oxygen
weakness, nausea, irritability. Helminthes D. Patient has to be exposed to the fresh air
of white color and 5-10 mm long have been E. Respiratory centers have to be stimulated
found on the underwear. On microscopy of 107. Patient 54 year-old, 5th day
the scrape from the perianal folds achromic after surgical operation. Blood count:
ova of the unsvmmetrical form have been Erythrocytes 3, 6* 1012/l, Hemoglobin 95 g/l,
revealed. Which helminth is in the organism Erythrocyte's hemoglobin content (color
of the child? index) 0,78; Leukocytes 16 * 109/l, Platelets
A. Trichina 450*109/l. Blood picture: anizocytosis,
B. Enterobins vermicularis poikilocytosis,
C. Ascaris lumbricoides reticulocytes- 3,8%. What anemia
D. Ancylostoma duodenalis does this patient have?
E. Trichuris A. Acquired hemolytic anemia
103. A 68-year-old woman can not move B. Acute posthemorragic anemia
her upper and lower right extremities after C. Hypoplastic anemia
stroke. Muscle tone of these extremities and D. Anemia from iron deficiency
reflexes are increased. There are pathological E. Chronic posthemorragic anemia
reflexes. What form of the paralysis is it? 108. A woman who was sick with rubella
A. Hemiplegia during the pregnancy gave birth to a deaf
B. Dissociation child with hare lip and cleft palate. This
C. Paraplegia congenital defect is an example of:
D. Monoplegia A. Down's syndrome
E. Tetraplegia B. Edward's syndrome
104. After breathing with poisonous steams C. Genocopy
there is an increased quantity of slime in D. Phenocopy
respiratory passages of a chemical production E. Patau's syndrome
worker. What of respiratory tract epithelial 109. A 22-year-old patient was admitted
cells participate in mucousa moistening? to the hospital with complaints of heavy
A. Intercalated cells nasal breathing. During the examination
B. Goblet cells of her nasal cavity the doctors found thickened
C. Endocrine cells mucous membrane, a lot of mucus
D. Langergans cells and nodular infiltrates without erosions in
E. Fibroblasts the nose. The nasal rhinoscleroma was diagnosed.
105. A 16 year-old patient got numerous The biopsy was taken. What typical
traumas in automobile accident. Now the morphological changes may be found?
patient is having a shock. AP - 80/60 mm A. Granulomas with Virchow's cells
Hg. daily urine volume 60-80 m!. What B. Granulomas with foreign body cells
pathogenic mechanism leads to kidneys C. Interstitial inflammation
function violation? D. Granulomas with Mikulicz's cells
A. Decreased hydrostatic pressure m E. Granulomas with Langhan's cells
glomerular capillaries 110. The alternate usage of dichlotiazide,
B. Increased vasopressin blood concentration etacrin acid and lasex did not cause marked
C. Trauma of the urinary bladder diuretic effect in the patient with marked
D. Increased osmotic pressure in glomerular peripheral edema. The aldosterone level in
capillaries the blood is increased. Indicate which medicine

12. should be prescribed: E. Pathological anisocytosis
A. Amilorid 116. Glomerular filtration rate (GFR)
B. Urea increased by 20% due to prolonged starvation
C. Clopamid of the person. The most evident cause of
D. Mannit filtration changes under this conditions is:
E. Spironolacton A. Increase of filtration coefficient
111. A patient with tissue trauma was taken B. Increase of penetration of the renal filter
a blood sample for the determination of C. Decrease of oncotic pressure of blood
blood clotting parameters. Specify the right plasma
sequence of extrinsic pathway activation. D. Increase of systemic blood pressure
A. III- VIIa - Xa E. Increase of renal plasma stream
B. IV - VIII: TF - Xa 117. There is the change of teeth at the 6,8year-
C. IV - VIIa-Xa old children: deciduous are replaced
D. III- VIII: TF - Xa by permanent. What embrionic tissues are
E. III-IV-Xa the sources of formation of permanent teeth
112. A damage of the atomic power plant tissues?
reactor resulted in the run-out of radioelements. A. I, II brachial arches
People in the superstandard radiation zone were B. Mesodermal epithelium and mesenhime
radiated with approximately C. Ectodermal epithelium of a tooth plate
250-300 r. and were immediately and Inesenhin1c
hospitalized. What changes in the blood D. Entodermal epithelium of a tooth plate
count would be typical? and mesenhime
A. Lymphopenia E. Entodermal epithelium and mesoderm
B. Neutropenia 118. A 50 year-old patient had hemorrhage
C. Leukopenia of the brain and was taken to the hospital.
D. Thrombopenia The place of hemorrhage was revealed
E. Anemia on the lateral hemispheres surfaces during
113. Decreased blood supply to the organs the medical examination. What artety was
causes hypoxia that activates fibroblasts injured?
function. Volume of what elements is A. The middle cerebral artery
increased in this case? B. The posterior cerebral artery
A. Nerve elements C. The anterior cerebral artery
B. Lymphatic vessels D. The posterior communicating artery
C. Vessels of microcircular stream E. The anterior conmmunicating artery
D. Parenchymatous elements of the organ 119. While enrolling a child to school
E. Intercellular substance Mantu's test was made to define whether
114. Live vaccine is injected into the human revaccination was needed. The test result is
body. Increasing activity of what cells of negative. What does this test result mean?
connective tissue can be expected? A. Absence of antitoxic immunity to the
A. Fibroblasts and labrocytes tuberculosis
B. Adipocytes and adventitious cells B. Presence of cell immunity to the
C. Pigmentocytes and pericytes tuberculosis
D. Plasmocytes and lymphocytes C. Presence of antibodies for tubercle bacillus
E. Macrophages and fibroblasts D. Absence of antibodies for tubercle bacillus
115. In the blood of a 26-year-old man E. Absence of cell immunity to the
18% of erythrocytes of the spherical, ball-shaped, tuberculosis
flat and thorn-like shape have been 120. Some diseases reveal symptoms
revealed. Other eritrocytes were in the form of aldosteronism with hypertension and
of the concavo-concave disks. How is this edema due to sodium retention in the
phenomenon called? organism. What organ of the internal
A. Erytrocytosis secretion is affected on aldosteronism?
B. Physiological anisocytosis A. Adrenal glands
C. Pathological poikilocytosis B. Pancreas
D. Physiological poikilocytosis C. Hypophysis

13. D. Testicle A. Macrophages, monocytes
E. Ovaries B. NK-cells
121. Oval and round organelles with double C. Fibroblasts. T-Iymphocytes, B-lymphocytes
wall are seen at the electron micrograph. D. T-Iymphocytes, B-Iymphocytes
The outer membrane is smooth, the inner E. O-lymphocytes
membrane folded into cristae contain 126. An autopsy has revealed that kidneys
enzyme ATPase synthetase. These are: are enlarged, surface is large-granular
A. Golgi complex because of multiple cavities with smooth
B. Centrioles wall, which are filled with clear fluid. What
Co Mitochondria kidney disease did the patient have?
D. Lysosomes A. Pyelonephritis
E. Ribosomes B. Infarction
122. A patient with encephalopathy was C. Glomerulonephritis
admitted to neurological department. D. Polycystic kidney
Correlation of increasing encephalopathy E. Necrotic nephrosis
and substances absorbed by the 127. During the operation on the hip joint
bloodstream from the intestines was revealed. of a 5-year-old child her ligament was
What substances created in the damaged which caused bleeding. What ligament
intestines can cause endotoxemia? was damaged?
A. Biotin A. Iliofemoral
B. Indole B. Ischiofemoral
C. Ornithine C. The head of the thigh
D. Butyrate D. Perpendicular of the acetabule
E. Acetacetate E. Pubofemoral
123. A 19 year-old patient was diagnosed 128. A 57-year-old patient was admitted
with appendicitis and was hospitalized. The to the gastroenterological department with
surgical operation on ablating appendix suspicion of Zollinger-Ellison syndrom
vermiformis is to be performed. What because of rapid increase of gastrin level in
artery must be fixed to stop bleeding during the blood serum. What the most probable
the surgical operation? disorder of the secretory function of the
A. The colica media stomach here?
B. The iliac A. Hypoacidity hyposecretion
C. The colica dextra B. Hyperacidity hypersecretion
D. The ileocolic artery C. Achylia
E. The colica sinistra D. Hypoacidity hypersecretion
124. Methotrexate (structural analogue of E. Hyperacidity hyposecretion
the folic acid which is competitive inhibitor 129. A 2-year-old child has got intestinal
of the dihydrofolatreductase) is prescribed dysbacteriosis, which results in hemorrhagic
for treatment of the malignant tumour. syndrome. What is the most likely cause of
On which level does methotrexate hinder hemorrhage of the child?
synthesis of the nucleic acids? A. Hypocalcemia
A. Processing B. PP hypovitaminosis
B. Mononucleotide synthesis C. Activation of tissue thromboplastin
C. Transcription D. Fibrinogen deficiency
D. Reparation E. Vitamin K insufficiency
E. Replication 130. A patient suffering from thyrotoxicosis
125. A patient with clinical signs symptoms of vegetoasthenic syndrome
of immunodeficiency has unchanged was revealed. What of the following would
number and functional activity of show the histological appearance of a
T and B lymphocytes. Dysfunction's thyroid gland being stimulated by
defect of antigen-presentation to the thyroidstimulating
immunocompetent cells was found during hormone (TSH)?
investigation on the molecule level. Defect A. Columnar-shaped follicular cells
of what cells is the most probable here? B. An abundance of colloid in the lumen of

14. the follicle human blood sample is lower than normal.
C. Increased numbers of parafollicular cells This leads to edema of tissues. What blood
D. Decreased numbers of parafollicular function is damaged?
capillaries A. Maintaining the Ph level
E. Decreased numbers of follicular cells B. Maintaining the. blood sedimentation
131. The action of electric current on the system
exitable cell caused depolarization of its C. All answers are correct
membrane. Movement of what ions through D. Maintaining the oncotic blood pressure
the membrane caused depolarisation? E. Maintaining the body temperature
A. Ca2+ 136. In the microspecimen of red bone
B. HCO3- marrow multiple capillares were revealed
C. K+ through the walls of which mature blood
D. CL- cells penetrated. What type of capillares is
E. Na+ it?
132. A young man has an unpainfull A. Fenestrational
formation without marked borders in the B. Somatical
soft tissues of his thigh. On the tissue bioptate C. Visceral
the formation lookes like flesh of D. Sinusoidal
fish and consists of immature fibroblast-like E. Lymphatic
cells with multiple mitosis growing through 137. A lung of a premature infant is
the muscles. What is the most likely diagnosis? presented on electronic photomicrography
A. Myosarcoma of biopsy material. Collapse of the alveolar
B. Cancer wall caused by the deficiency of surfactant
c. Myoma was revealed. Disfunction of what cells of
D. Fibrosarcoma the alveolar wall caused it?
E. Fibroma A. Secretory cells
133. A 46 year-old patient has complained B. Alveolar macrophages
of headache, fatigue, thirst, pains in the spine C. Alveocytes type II
and joints for the last 2 years. Clinically D. Fibroblasts
observed disproportional enlargement of E. Alveocytes type I
hands, feet, nose, superciliary arches. He 138. A patient had been taking glucocorticoids
notes that he needed to buy bigger shoes for a long time. When the preparation
three times. What is the main reason of such was withdrawn he developed the symptoms
disproportional enlargement of different of disease aggravation, decreased blood
parts of the body? pressure and weakness. What is the reason
A. Increased sensitivity of the tissues to of this condition?
insulin . A. Sensibilization
B. Joints dystrophy development B. Appearance of adrenal insufficiency
C. Cartilaginous tissue proliferation under C. Cumulation
growth hormone influence n. Hyperproduction of ACTH
D. Increased sensitivity of the tissues to E. Habituation
growth hormone 139. A 2-vear-old child experienced
E. Joints chronic inflammation development convulsions because of lowering calcium
134. A tissue sample of benign tumor was ions concentration in the blood plasma.
studied under the electron microscope. A Function of what structure is decreased?
lot of small (15-20 nm) spherical bodies, A. Parathyroid glands
consisting of 2 unequal subunits were B. Hypophysis
detected. These are: C. Adrenal cortex
A. Microtubules D. Pineal gland
B. Smooth endoplasmic reticulum E. Thymus
C. Ribosomes 140. During the fetal period of the
D. Mitochondria development in the vascular system of
E. Golgi complex the fetus a large arterial (Botallo's)
135. The concentration of albumins in duct is functioning which converts into

15. lig .arteriosum after birth. What anatomical B. Monocvtes
formations does this duct connect? C. Eosinophiles
A. Aorta and superior vena cava D. Lymphocytes
B. Pulmonary trunk and aorta E. Platelets
C. Right and left auricle 146. A 55-year-old patient with continuing
D. Aorta and inferior vena cava ventricular arrhythmias was admitted to
E. Pulmonary trunk and superior vena cava the hospital. The patient is taking timolol
141. The B cells of endocrine portion of drops for glaucoma, daily insulin injections
pancreas are selectively damaged by alloxan for diabetes mellitus, and an ACE inhibitor
poisoning. How will it be reflected in blood for hypertension. You have decided to use
plasma? phenytoin instead of procainamide. What is
A. The content of globulins decreases the reason?
B. The level of sugar decreases A. The hypertensive effects of procainamide
C. The content of albumins decreases would aggravate the hypertension
D. The content of sugar increases B. The anticholinergic effect of procainamide
E. The content of fibrinogen decrease would aggravate glaucoma
142. A consumptive patient has an open C. The cholinergic effects of procainamide
pulmonary form of disease. Choose what would aggravate the diabetes
sputum staining should be selected for finding D. The local anesthetic effect of procainamide
out the tubercle (Koch's) bacillus? would potentiate diabetes
A. Method of Burry-Gins E. The local anesthetic effect of procainamide
B. Method of Ziel-Neelsen would aggravate the hypertension
C. Method of Gram 147. Patient with diabetes mellitus experienced
D. Method of Romanowsky-Giemsa loss of consciousness and convulsions
E. Method of Neisser . after an injection of insulin. What might be
143. During the breakout of acute respiratory the result of biochemical blood analysis for
infection in order to diagnose concentration of sugar?
influenza the express-diagnosis, based on A. 3,3 mmol/L
revealing of specific viral antigen in the B. 8,0 mmol/L
examined material (nasopharyngial lavage), C. 10,0 mmol/L
is carried out. Which reaction is used for D. 1.5 mmol/L
this? E. 5,5 mmol/L
A. Opsonization 148. Moving of the daughter chromatids to
B. Complement binding the poles of the cell is observed in the mitotically
C. Immunofluorescence dividing cell. On what stage of the
D. Agglutination mitotic cycle is this cell?
E. Precipitation A. Anaphase
144. A 62-year-old patient was admitted to B. Interfase
the neurological department due to cerebral C. Prophase
haemorrage. His condition is grave. There is D. Telophase
evident progression of deep and frequent E. Metaphase
breath that turnes into reduction to apnoea 149. A 25-year-old woman with red and
and the cycle repeates. What respiration itchy eczematoid dermatitis visits your
type has developed in the patient? office, She had a dental procedure one
A. Gasping respiration day earlier with administration of a local
B. Biot's respiration anesthetic. There were no other findings,
C. Cheyne-Stockes respiration although she indicated that she had a history
D. Apneustic respiration of allergic reactions. Which of the
E. Kussmaul respiration following drugs is most likely involved?
145. Punctata hemorrhage was found out in A. Procaine
the patient after application of a tourniquet. B. Etidocaine
With disfunction of what blood cells is it C. Bupivacaine
connected? D. Cocaine
A. Neutrophiles E. Lidocaine

16. 150. A mother of a newborn complains C. Autosomal dominant
of her baby's constant belching with undigested D. X-linked recessive
milk. Which developmental anomaly E. Y-linked
is it an evidence of? 156. A patient's blood was analyzed and
A. Esophageal atresia the decreased erythrocyte's sedimentation
B. Esophageal fistula rate (ESR) was discovered. What disease
C. Labium leporium from the listed below is accompanied with
D. Faux lupinum decreased ESR?
E. Anal atresia A. Vitamin B deficiency
151. Autopsy of the 58-year-old man hads B. Hepatitis
revealed that mitral valve is deformed, thickened, C. Polycytemia
does not totally close, Microscopically: D. Myocardial infarction
centers of collagen fibers are eosinophilic, E. Splenomegaly
have positive fibrin reaction. The 157. The pulmonalis embolism has suddenly
most probable diagnosis is: developed in a 40 year-old patient with
A. Mucoid swelling opened fracture of the hip. Choose the
B. Fibrinoid inflammation possible kind of embolism.
C. Amyloidosis A. Thrombus-embolus
D. Fibrinoid swelling B. Air
E. Hyalinosis C. Tissue
152. During surgical operation a blood D. Foreign body
transfusion was made. The blood must be E. Fat
checked to find antigens of some disease. 158. Where should the cathetor for
What disease is expected to be found? evacuation of the lymph from the thoracic
A. Virus of hepatitis A lymph duct be inserted?
B. Enterovirus A. To the inferior vena cava
C. Virus of hepatitis B B. To the right venous corner
D. Virus of hepatitis E C. To the left inguinal vein
E. Adenovirus D. To the left venous corner
153. Electrocardiogram of a 45-year-old E. To the superior vena cava
man showed absence of P-wave in all the 159. A 42-year-old man who has been
leads. What part of the conducting system is injured in a car accident is brought into the
blocked? emergency room. His blood alcohol level on
A. Atrioventricnlar node admission is 250 mg/dL. Hospital records
B. Common branch of the bundle of His show a prior hospitalization for alcohol
C. Purkinje's fibres related seizures. His wife confirms that he
D. Branches of the bundle of His has been drinking heavily for 3 weeks. What
E. Sinu-atrial node treatment should be provided to the patient
154. Nowadays about 50 minor bases have if he goes into withdrawal?
been found ill the t-RNA structure besides A. None
the main four nitrogenous bases. Choose B. Pentobarbital
the minor nitrogenous base: C. Phenobarbital
A. Adenine D. Diazepam
B. Cytosine E. Phenytoin
C. Cysteine 160. Synthesis of phospholipids is disordered
D. Uracil under the liver fat infiltration.
E. Dihydrouracil Indicate which of the following substances
155. A healthy woman has three sons can enhance the process of methylation
affected by color blindness who were born during phospholipids synthesis?
after her two marriages. Children both of A. Citrate
her husbands are healthy. What is the most B. Ascorbic acid
possible pattern of inheritance of this disease? C. Methionine
A. Autosomal recessive D. Glycerin
B. X-linked dominant E. Glucose

17. 161. A patient with the symptoms of acute E. Mineralocorticoids
alcoholic poisoning was brought to the 165. A 60-year-old patient was diagnosed
hospital. What carbohydrates metabolism with hypothalamic lateral nuclei stroke.
changes are typical for this condition? What changes in patient's behavior may be
A. The g]uconeogenesis is increased in liver expected?
B. The anaerobic glucose metabolism A. Depression
predominates in muscles B. Aggressive behaviour
C. The breakage of glycogen is increased in C. Thirst
liver D. Unsatisfied hunger
D. The anaerobic breakage of glucose is E. The rejection of food
increased in muscles 166. A 55-year-old patient was hospitalized
E. The gluconeogenesis velocity in liver is in result of the trauma of the medial
decreased group of femoral muscles. What kind of
162. An individual is characterized by movements is the patient unable to do?
rounded face, broad forehead, a mongollan A. Abduction of femur
type of eyelid fold, flattened nasal bridge, B. Adduction of femur
permanently open mouth. projecting C. Flexion of femur
lower lip, protruding tongue, short neck, flat D. Extension of femur
hands, and stubby fingers. What diagnosis E. Suppination of femur
can be put to the patient? 167. The process of heart transplantation
A. Klinefelter's syndrome determined the viability of myocardial cells.
B. Supermales The determination of what myocardium
C. Down's syndrome parameter is the most important'?
D. Alkaptonuria A. Concentration of Ca-ions in heart vessels
E. Turner's syndrome B. Concentration of oxygen in heart vessels
163. A 40-year-old woman has had a feeling of C. Rest potential of cardiomyocytes
abdominal discomfort for the past D. Concentration of calcium-ions in myofibrils
8 months. On pelvic examination, there is E. Heart temperature
the right adnexal mass. Abdominal CT scan 168. A woman who was infected with
demonstrates a 7 Cm cystic mass involving toxoplasmosis during the pregnancy has a
the right ovary with small areas of child with multiple congenital defects. This
calcification. The uterus is normal in size. is a result of:
The right fallopian tube and ovary have A. Recombination
been removed surgically. Grossly, the mass B. Biological mutogenesis
on sectioning is filled with abundant hair C. Teratogenesis
and sebum. Microscopically, the mass has D. Chemical mutogenesis
glandular spaces lined by columnar epithelium, E. Cancerogenesis
squamous epithelium with hair follicles 169. The energy inputs of a healthy man
cartilage, and dense connective tissue. What have been measured. In what position was
type of tumour is it? the patient if his energy inputs were less
A. Teratoma than the main exchange?
B. Squamous cell carcinoma of ovary A. Nervous exertion
C. Metastase of cervical carcinoma B. Easy work
D. Melanoma C. Sleep
E. Sarcoma of ovary D. Rest
164. A 19-year-old female suffers from E. Calmness
tachycardia in rest condition, weight loss, 170. A patient after hypertension stroke
excessive sweating, exophtalmos and irritability. does not have voluntary movements in his
What hormone would you expect to right arm and leg with the increased muscle
find elevated in her scrum? tone in these extremites. What type of disfunction
A. Cortisol of nervous system is it?
B. Insulin A. Peripheral paresis
C. Thyroxine B. Peripheral paralysis
D.ACTH C. Central paresis

18. D. Central paralysis Malaria. What method of laboratory diagnostics
E. Reflex paresis is necessary to use?
171. The patient has come to the hospital A. Immunological tests
from the smelting workshop in the condition B. Blood examination
of hyperthermia. What is the direct cause C. Urine examination
of loss of consciousness at the heat stroke? D. Stool examination
A. Decreased brain blood supply E. Examination of vaginal and urethral
B. Dilatation of peripheral vessels discharge
C. Decrease of heart output 176. The patient with pneumonia was
D. Arterial pressure drop treated with antibiotics for a long period,
E. Increased water loss through sweating After treatment patient complains of
172. Scraps of the mycelium of a fungus, frequent and watery stool, abdomenal pain.
spores, air bubbles and fat drops were discovered What is the reason of intestine function disorder?
on microscopy of the patient's A. Bacteria toxins influence
hair excluded from the infected areas, What B. Intestinal disbacteriosis development
fungus disease is characterised by this C. Antibiotics toxic influence on the GIT
microscopic D. Autoimmune reaction development
picture? E. Hereditary enzyme defect
A. Epidermophytosis 177. Analeptical remedy of reflective type
B. Favus from the H-cholinomimetics group was given
C. Trichophytosis to the patient for restoration of breathing
D. Microspory after poisoning with carbon monoxide,
E. Sporotrichosis What medicine was prescribed to the patient?
173. A person was selling "homemade pork A. Adrenalin hydrochloride
"sausages on the market. State sanitary B. Atropine sulphate
inspector suspected falcification of the c. Mesaton
sausages, What serological immune reaction D. Pentamin
can identifiy food substance? E. Lobeline hydrochloride
A. Complement- fixation test 178. A patient complains of frequent and
B. Agglutination test difficult urination, Imperfection of what
C. Precipitation test formation can cause it?
D. Immunofluorescence test A. Prostate
E. Indirect hemagglutination test B. Testicle adnexa
174. A 45-year-old man fell on the right C. Testicles
knee and felt the acute pain in the joint On D. Sperm bubbles
examination: severe edema on the anterior E. Bulb-uretic glands
surface of the knee joint. Crunching sounds 179. A 10-year-old child complains of
are heard, while moving the joint. Which weakness, nausea, irritability. Helminthes of
bone is destroyed? while color and 5-10 mm long were found on
A. Left epicondyle of the thigh the underwear. On microscopy of the scrape
B. Knee-cap from the perianal folds achromic ovums of
C. Head of the thigh bone unsymmetrical form were revealed. Indicate
D. Neck of the thigh bone what helminth is parasiting on the child?
E. Right epicondyle of the thigh A. Trichina
175. A patient has been brought to the B. Trichuris
hospital with the complaints of headache, C. Enterobins vermicularis
pain in left hypochondrium. He has been D. Ancylostoma duodenalis
ill for 1,5 weeks, the sudden illness began E. Ascaris lumbricoides
with the increase of body temperature up 180. A microscopic examination of the
to 39,9°C. In 3 hours the temperature enlarged neck gland of a 14-year-old girl
decreased and hydropoiesis began. The revealed destruction of the tissue structure
attacks repeat rhythmically in 48 hours. of the node, absence of the lymph follicles,
The patient had visited one an African sclerotic and necrosis parts. Cell
Country. The doctors have suspected constitution of the node is polymorphous,

19. lymphocites, eosinophiles, atypical cells C. Decreased lungs elasticity
of the large size with mu1tiple-Iobule D. Inhibition of respiratory center
nuclei (Beresovsky-Shternberg cells) and E. Excitation of respiratory center
onenucleus large size cells are observed. 186. There is only One hormone among the
What is the most likely diagnosis? neurohormones which refers to the derivatives
A. Fungous mycosis of amino acids according to classification.
B. Acute lympholeucosis Point it out:
C. Berkitt's lymphoma A. Somatotropin
D. Chronic lympholcucosis B. Oxytocin
E. Lymphogranulomatous C. Vasopressin
181. Only one factor can influence the D. Melatonin
charge of amino acid radicals in the active E. Thyroliberin
centre of enzyme, Name this factor: 187. At the "laboratory experiment
A. The surplus of a product the eukocyte culture was mixed with
B. pH medium staphylococci. Neutrophile leukocytes
C. Temperature engulfed and digested bacterial cells. This
O. The presence of a competitive inhibitor processes are termed:
E. Pressure A. Phagocytosis
182. The donor who had not donated the B. Facilitated diffusion
blood for a long time was examined with C. Pinocytosis
IFA method, Anti-HBs antibodies were D. Osmosis
revealed, What does positive result of IFA E. Diffusion
in this case mean? 188. A 50-year-old male farm worker has
A. Chronic hepatitis C been brought to the emergency room. He
B. Acute hepatitis C was found confused in the orchard and since
C. Acute hepatitis B then has remained unconscious. His heart
D. Previous hepatitis B rate is 45 and his blood pressure is 80/40 mm
E. Chronic hepatitis B Hg. He is sweating and salivating profusely.
183. A patient has elbow joint trauma with Which of the following should be prescribed?
avulsion of medial epicondyle of humerus. A. Pentamine
What nerve can be damaged in this trauma? B. Norepinephrine
A. Radial C. Physostigmine
B. Medial cutaneous nerve of forearm D. Atropine
C. Cardiac cutaneous nerve E. Proserine
D. Musculocutaneous nerve 189. A young man felt sharp pain in the back
E. Ulnar during active tightening on the horizontal
184. A 35-year-old man under the treatment bar. Objectively: pain while moving upper
for pulmonary tuberculosis has acute-onset extremity, limited pronation and adduction
of right big toe pain, swelling, and low-grade functions. Sprain of what muscle can be
fever. The gouty arthritis was diagnosed and observed here?
high serum uric acid level was found. Which A. M.subscapularis
of the following antituberculosis drugs are B. M.latissimus dorsi
known for causing high uric acid levels? C. M.romboideus major
A. Rifampicin D. M.levator scapulae
B. Aminosalicylic acid E. M.trapezius
C. Thiacetazone 190. Intrapleural pressure is being measured
D. Pyrazinamide in a person. In what phase does a person
E. Cycloserine hold his breath if the pressure is - 25 cm
185. X-rav examination discovered lungs H20?
emphysema in the patient. What is the A. Forced expiration
reason of short breath development in this B. Quiet inspiration
case? c.-
A. Increased lungs elasticity D. Forced inspiration
B. Decreasing of alveoli receptors sensitivity E. Quiet expiration

20. 191. To anaesthetize the manipulation between tibia and fibula . What kind of bone
related to burn surface treatment, a patient connection was injured?
was intravenously injected a medication A. Fontanel
for short-acting narcosis. 1 minute B. Ligament
later the patient being under anaesthesia C. Membrane
had increased blood pressure, tachycardia, D. Suture
increased tone of sceletal muscles; reflexes E. Gomphosis
remained. After awakening the patient had 196. On autopsy a 35-year-old man the focus
desorientation and visual hallucinations. of carnification 5 cm in diametre enclosed
What medication was the patient injected? in a thin capsule was revealed in the second
A. Nitrous oxide segment of the right lung. The focus consists
B. Thiopental sodium of a tough dry friable tissue with a
C. Ketamine dim surface. For what disease are these
D. Diethyl ether morphological changes typical?
E. Sombrevin A. Lung cancer
192. The patient with diabetes mellitus has B. Tumorous form of silicosis
been delivered in hospital in the state of C. Postinftammatory pneumosclerosis
unconsciousness. Arterial pressure is low. D. Tuberculoma
The patient has acidosis. Point substances, E. Chondroma
which accumulation in the blood results in 197. A I8-year-old patient came to the outpatient
these manifestations: department wiith the complaints of
A. Cholesterol esters bleeding trauma in the vestibule of his nose.
B. High fatty acids On examination: the mechanical injure of
C. Monosaccharides the mucous laver of the vestibule without
D. Amino acids continuation into nasal cavity proper. What
E. Ketone bodies is the boundary between the vestibule and
193. A patient with hypersecretion of the nasal cavity proper?
gastric juices was recomended to exclude A. Nasal limen
concentrated bouillons and vegetable B. Nostrils
decoctions from the diet because of their C. Nasal septa
stimulation of gastric secretion. What is D. Choanes
dominating E. Nasal roller
mechanism of stimulation of secretion 198. A 52 year-old patient with bronchial
in this case? asthma was treated with glucocorticoids.
A. Stimulation of excretion of secretion in the Fever reaction appeared as a result of
duodenum postinjective
B. Irritation of taste receptors abscess. The patient had subfebrile
C. Stimulation of gastrin production by temperature, which didn't correspond
G-cells to latitude and severity of inflamnmatory
D. Irritation of mechanoreceptors of the process. Why did patient have low fever
stomach reaction?
E. Irritation of mechanoreceptors of the oral A. Inhibited endogen pyrogens production
cavity B. Violation of heat-producing mechanisms
194. Pyruvate concentration in the patient's C. Thermoregulation center inhibition
urine has increased 10 times from normal D. Inflammatory barrier formation in injection
amount. What vitamin deficiency can be the place
reason of this change: E. Violation of heat loss through lungs
A. Vitamin Bl 199. Purulent endometritis developed in a woman
B. Vitamin Bb after delivery. Treating with antibiotics
C. Vitamin C inhibitors of murein synthesis was
D. Vitamin A ineffective. Wide spectrum bactericidal
E. Vitamin E antibiotic was administered to her. In 6
195. A 6-year-old child fell on the cutting hours temperature rapidly increased up
object and traumatized soft tissues to 40°C with shiver. Muscle pains have

21. appeared. BP dropped down to 70/40
mmHg. Oligura has developed. What is the
main reason for the development of this
condition?
A. Toxic effect of preparation
B. Endotoxic shock
C. Internal bleedin
D. Anaphylactic shock
E. Bacteremia
200. A patient in three weeks after acute
myocardial infarction has pain in the heart
and joints and pneumonia. What is the
main mechanism of development of
postinfarction
Dressler's syndrome?
A. Autoimmune inflammation
B. Resorption of enzymes from necrotized
area of myocardium
C. Secondary infection
D. Ischemia of myocardium
E. Thrombosis vessels