4. what is NIBP?
a noninvasive
method for
measuring the blood
pressure of
laboratory animals
(dog, primates, etc.)
www.emka.fr
5. how does it work?
emka TECHNOLOGIES’ noninvasive blood
pressure systems are based on the
oscillometric technique: pressure is
measured from a cuff around a limb or the
tail that is inflated to block blood flow then
deflated slowly
www.emka.fr
7. 2 different solutions
emkaPACK
nibp is an optional feature of our
emkaPACK noninvasive telemetry system -
suitable for long term measurements on
unrestrained animals
nibpSNAPSHOT
self-contained, handheld device designed
for single-point measurements
both supplied with dedicated software for data acquisition &
analysis
www.emka.fr
8. common features
low and high pressure range 0-300mmHg
adjustable deflation speed 5mmHg/s –
15mmHg/s
linear deflation speed
high speed servo-control by instant pressure and
dPdt
adjustable pulse amplification 5x-100x
www.emka.fr
10. designed for the emkaPACK system
single-shot or programmable cyclic operation
embedded calibration information
www.emka.fr
11. setting-up the animal
tail is shaved
cuff is wrapped around the
tail and connected to the
transmitter
a custom velcro extension
protects the cuff, and
maintains it in the proper
position on the tail
www.emka.fr
14. features
handheld device
USB connection to computer
powered through USB
both a NIBP device and a 7-leads ecg device
designed for single-point measurements
measurements can be repeated every 10s if
necessary
www.emka.fr
17. real-time & off-line software analysis
ecgAUTO
real-time analysis
performed by iox2
(nibpSNAPSHOT, emkaPACK,
emkaPACK 4G)
off-line analysis
performed by ecgAUTO
(nibpSNAPSHOT, emkaPACK,
TOE)
control by iox2
www.emka.fr
18. parameters computed from the deflation curve
alone
ecgAUTO
systolic blood pressure
diastolic blood pressure
mean blood pressure
www.emka.fr
20. real-time analysis in iox2
cuff pressure pulse
vs time amplitude vs
cuff pressure
pressure
pulses and ecg
www.emka.fr
21. off-line analysis in ecgAUTO
cuff pulse
pressure amplitude vs
vs time cuff pressure
pressure
pulses and ecg
www.emka.fr
22. how is analysis performed?
ecgAUTO
detects inflation cycles
applies hi-pass filter
selects valid blood pressure pulses
produces bell shaped amplitude curve
computes mean, systolic and diastolic
pressure values
www.emka.fr
23. what are the challenges for a successful
analysis?
when signal is noisy the algorithm picks pulses
that correspond to blood pressure beats and
ignores artefacts
for greater efficiency, the software applies a
number of criteria and rejects unreliable or
spurious results
present experience (around 1000 hours of data
from 40 dogs) indicate that from 70 to 95% of
inflation cycles produce reliable data
www.emka.fr
24. examples of good and poor quality signals
pulses from noisy zones are ignored
www.emka.fr