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2 solutions
 for noninvasive blood
 pressure
 measurement
 emkaPACK & nibpSNAPSHOT

 smart tools – swift services – sharp research
  www.emka.fr
www.emka.fr
noninvasive blood pressure
 measurement

                              A
 overview
                              B
 emkaPACK
                              C
 nibpSNAPSHOT
                              D
 software analysis


www.emka.fr
overview
              A
www.emka.fr
what is NIBP?
a noninvasive
method for
measuring the blood
pressure of
laboratory animals
(dog, primates, etc.)


www.emka.fr
how does it work?


emka TECHNOLOGIES’ noninvasive blood
pressure systems are based on the
oscillometric technique: pressure is
measured from a cuff around a limb or the
tail that is inflated to block blood flow then
deflated slowly

www.emka.fr
what is analyzed?




                    cuff pressure




                                    time
www.emka.fr
2 different solutions
emkaPACK
nibp is an optional feature of our
emkaPACK noninvasive telemetry system -
suitable for long term measurements on
unrestrained animals
nibpSNAPSHOT
self-contained, handheld device designed
for single-point measurements
both supplied with dedicated software for data acquisition &
analysis
www.emka.fr
common features

low and high pressure range 0-300mmHg
adjustable deflation speed     5mmHg/s –
15mmHg/s
linear deflation speed
high speed servo-control by instant pressure and
dPdt
adjustable pulse amplification 5x-100x
www.emka.fr
emkaPACK
              B
www.emka.fr
designed for the emkaPACK system
single-shot or programmable cyclic operation
embedded calibration information
www.emka.fr
setting-up the animal

tail is shaved
cuff is wrapped around the
tail and connected to the
transmitter
a custom velcro extension
protects the cuff, and
maintains it in the proper
position on the tail

www.emka.fr
nibpSNAPSHOT
                 C
www.emka.fr
nibpSNAPSHOT




www.emka.fr
features

handheld device
USB connection to computer
powered through USB
both a NIBP device and a 7-leads ecg device
designed for single-point measurements
measurements can be repeated every 10s if
necessary
www.emka.fr
specifications




www.emka.fr
software analysis
                      D
www.emka.fr
real-time & off-line software analysis
ecgAUTO

real-time analysis
performed by iox2
(nibpSNAPSHOT, emkaPACK,
emkaPACK 4G)

off-line analysis
performed by ecgAUTO
(nibpSNAPSHOT, emkaPACK,
TOE)

control by iox2


www.emka.fr
parameters computed from the deflation curve
alone
ecgAUTO




systolic blood pressure
diastolic blood pressure
mean blood pressure



www.emka.fr
parameters computed with simultaneous ecg
ecgAUTO




heart rate
pressure transit time




www.emka.fr
real-time analysis in iox2

cuff pressure                      pulse
vs time                        amplitude vs
                               cuff pressure




                              pressure
                              pulses and ecg



 www.emka.fr
off-line analysis in ecgAUTO

cuff                                 pulse
pressure                         amplitude vs
vs time                          cuff pressure




                                pressure
                                pulses and ecg



 www.emka.fr
how is analysis performed?
ecgAUTO

detects inflation cycles
applies hi-pass filter
selects valid blood pressure pulses
produces bell shaped amplitude curve
computes mean, systolic and diastolic
pressure values

www.emka.fr
what are the challenges for a successful
analysis?
when signal is noisy the algorithm picks pulses
that correspond to blood pressure beats and
ignores artefacts
for greater efficiency, the software applies a
number of criteria and rejects unreliable or
spurious results
present experience (around 1000 hours of data
from 40 dogs) indicate that from 70 to 95% of
inflation cycles produce reliable data
www.emka.fr
examples of good and poor quality signals
pulses from noisy zones are ignored




www.emka.fr
facebook :
   www.facebook.com/emkaTECHNOLOGIES
     twitter :
     @emkaTECH
  www.emka.fr
www.emka.fr
solutions for
 lifesciences
 research
  www.emka.fr
www.emka.fr

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2 solutions for noninvasive blood pressure measurement

  • 1. 2 solutions for noninvasive blood pressure measurement emkaPACK & nibpSNAPSHOT smart tools – swift services – sharp research www.emka.fr www.emka.fr
  • 2. noninvasive blood pressure measurement A overview B emkaPACK C nibpSNAPSHOT D software analysis www.emka.fr
  • 3. overview A www.emka.fr
  • 4. what is NIBP? a noninvasive method for measuring the blood pressure of laboratory animals (dog, primates, etc.) www.emka.fr
  • 5. how does it work? emka TECHNOLOGIES’ noninvasive blood pressure systems are based on the oscillometric technique: pressure is measured from a cuff around a limb or the tail that is inflated to block blood flow then deflated slowly www.emka.fr
  • 6. what is analyzed? cuff pressure time www.emka.fr
  • 7. 2 different solutions emkaPACK nibp is an optional feature of our emkaPACK noninvasive telemetry system - suitable for long term measurements on unrestrained animals nibpSNAPSHOT self-contained, handheld device designed for single-point measurements both supplied with dedicated software for data acquisition & analysis www.emka.fr
  • 8. common features low and high pressure range 0-300mmHg adjustable deflation speed 5mmHg/s – 15mmHg/s linear deflation speed high speed servo-control by instant pressure and dPdt adjustable pulse amplification 5x-100x www.emka.fr
  • 9. emkaPACK B www.emka.fr
  • 10. designed for the emkaPACK system single-shot or programmable cyclic operation embedded calibration information www.emka.fr
  • 11. setting-up the animal tail is shaved cuff is wrapped around the tail and connected to the transmitter a custom velcro extension protects the cuff, and maintains it in the proper position on the tail www.emka.fr
  • 12. nibpSNAPSHOT C www.emka.fr
  • 14. features handheld device USB connection to computer powered through USB both a NIBP device and a 7-leads ecg device designed for single-point measurements measurements can be repeated every 10s if necessary www.emka.fr
  • 16. software analysis D www.emka.fr
  • 17. real-time & off-line software analysis ecgAUTO real-time analysis performed by iox2 (nibpSNAPSHOT, emkaPACK, emkaPACK 4G) off-line analysis performed by ecgAUTO (nibpSNAPSHOT, emkaPACK, TOE) control by iox2 www.emka.fr
  • 18. parameters computed from the deflation curve alone ecgAUTO systolic blood pressure diastolic blood pressure mean blood pressure www.emka.fr
  • 19. parameters computed with simultaneous ecg ecgAUTO heart rate pressure transit time www.emka.fr
  • 20. real-time analysis in iox2 cuff pressure pulse vs time amplitude vs cuff pressure pressure pulses and ecg www.emka.fr
  • 21. off-line analysis in ecgAUTO cuff pulse pressure amplitude vs vs time cuff pressure pressure pulses and ecg www.emka.fr
  • 22. how is analysis performed? ecgAUTO detects inflation cycles applies hi-pass filter selects valid blood pressure pulses produces bell shaped amplitude curve computes mean, systolic and diastolic pressure values www.emka.fr
  • 23. what are the challenges for a successful analysis? when signal is noisy the algorithm picks pulses that correspond to blood pressure beats and ignores artefacts for greater efficiency, the software applies a number of criteria and rejects unreliable or spurious results present experience (around 1000 hours of data from 40 dogs) indicate that from 70 to 95% of inflation cycles produce reliable data www.emka.fr
  • 24. examples of good and poor quality signals pulses from noisy zones are ignored www.emka.fr
  • 25. facebook : www.facebook.com/emkaTECHNOLOGIES twitter : @emkaTECH www.emka.fr www.emka.fr
  • 26. solutions for lifesciences research www.emka.fr www.emka.fr