1. The Open Drug Discovery Teams (ODDT) Mobile App For Malaria
Sean Ekins1 and Alex M. Clark2
1
Collaborations in Chemistry, 5616 Hilltop Needmore Road, Fuquay Varina, NC 27526, U.S.A., 2 Molecular Materials Informatics, 1900 St. Jacques #302, Montreal, Quebec,
Canada H3J 2S1.
What is Malaria?
Malaria infects ca. 200 million people and causes over 1 million deaths per year, disproportionately claiming African children under the age of 5 years. The rapid and pervasive emergence of antimalarial
resistance has led to a re-emergence of the disease in areas where it was once controlled. Of particular concern are chloroquine resistant Plasmodium strains, which can result in an increase in malaria
mortality. Unfortunately, research focused on malaria is largely comprised of disjointed efforts of many academic and other non-profit laboratories distributed across the globe. Medicines for Malaria
Ventures manage over 50 antimalarial projects in collaboration with over 80 pharmaceutical, academic, and endemic-country partners in 44 countries. We believe there is a need for a new approach to
foster inter-group collaboration to speed up drug discovery and that social media and mobile technologies can play a role. The impact of accelerating the identification and advancement of promising
antimalarial lead compounds through the efforts of a collaborative network of top antimalarial researchers, very simply, can be measured in terms of the potential number of lives saved.
The Open Drug Discovery Teams (ODDT) project uses a free mobile app as user entry point http://tinyurl.com/6l9qy4f. The app has a magazine-like interface, and server-side infrastructure for hosting
chemistry-related data as well as value added services. The project is open to participation from anyone and provides the ability for users to make annotations and assertions, thereby contributing to the
collective value of the data to the engaged community. The infrastructure for the app is currently based upon the Twitter API and uses Google Alerts RSS feeds as a useful proof of concept for a real time
source of publicly generated content.
We now highlight how ODDT can be used as an electronic notebook to share new scientific data on malaria and engage this research community by following #malaria using Twitter and
Google Alerts.
Capture and link to recent news and Diverse content repository
Content collected ready papers published worldwide
@collabchem
for viewing
tweets with
#malaria
B
Content from web
Blogs used as Open Lab notebooks
The App
Merges Twitter and Web
content seamlessly
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