We have successfully uncovered and mapped the most comprehensive long-distance network of the Macaque monkey brain, which is essential for understanding the brain’s behavior, complexity, dynamics and computation.
Network architecture of the long-distance pathways in the macaque brain
1. Network Architecture of the Long-Distance Pathways in the Macaque Brain Modha, D. S. & Singh, R. (July 12, 2010) Proc. Natl. Acad. Sci. USA, 10.1073/pnas.1008054107 Dharmendra S Modha IBM Research – Almaden Raghavendra Singh IBM Research – India
2. Consensus dendrogram of a network of species Clauset, Moore, Newman, Nature, 2008 Topological modules in E. coli metabolism Ravasz, Somera, Mongru, Oltvai, Barabasi Science, 2002 Cartographic representation of the metabolic network of E. Coli Guimera, Amaral, Nature 2005 Map of protein–protein interactions Jeong, Mason, Barabasi, Oltvai, Nature 2001 Networks are Everywhere
3. The human brain is the most complex mass of protoplasm on earth-perhaps even in our galaxy. Marian C. Diamond, Arnold B. Scheibel
5. Multiple Scales of The Brain Network Brainbow Livet et al, Nature 2007 Denk, Seung, et al, 2007 Hagman et al, PLoS Biology 2008 Binzeggar, Douglas, Martin, J. Neurosci. 2004
42. Comprehensive Includes every study in CoCoMac Consistent Every connection can be tracked back Concise 6,877 areas to 383 Coherent Unified hierarchical parcellation Colossal 3 times larger than previous network C, C, C, C, and C
53. Brain is small-world, Core is “tiny”-world! Core contains only 32% of vertices yet 88% of all edges originate or terminate in the core 0.39 0.33 Average Clustering Coefficient 1.95 2.62 Characteristic Path Lengh 4 6 Diameter Core Brain
54. Core contains correlated-anti-correlated networks and may be a key to higher cognition & consciousness Fox, Snyder, Vincent, Corbetta, Van Essen, and Raichle, 2005