Amgen launched a formal environmental sustainability program in 2007. They have found success by knowing their current performance, having a strategy with goals, improving existing operations, planning for more efficient future facilities, integrating sustainability into core operations, and announcing results. Their program has reduced energy, water, waste, and emissions while gaining recognition awards. The document outlines Amgen's sustainability approach and achievements in various areas like energy, water, waste, and manufacturing.

1. AMGEN Sustainability Program
VCEDA Business Outlook Conference
October 2011

2. Amgen Is a Pioneer in Discovery and
Delivery of Vital Medicines
• World’s leading independent
biotechnology company, with a
mission to serve patients
– Amgen medicines have reached 20
million patients Marketed Products
– Presence in nearly 50 countries
• More than 30 years of pioneering
science and vital medicines
• Focus solely on discovering,
developing, and making human
therapeutics
– Specializing in innovative medicines
for serious illness
– Pioneer and world leader in protein
therapeutic manufacturing
• Broad and deep pipeline of novel
product candidates
For additional information about Amgen products, including
important safety information, visit www.amgen.com
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3. Amgen Launched a Formal Environmental
Sustainability Program in 2007
What we’ve found that leads to success:
• Know where you are
• Have a strategy
• Set goals
• Improve what you have
• Plan for the future
• Build sustainability into the core of your business
• Announce results
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4. Know Where You Are: Compare
Performance With Industry Peers
Total Energy Carbon Dioxide
Metric Tons / Sq Feet
Gigajoules / Sq Feet
1.5 0.12
0.09
1
0.06
0.5 0.03
0
0 Amgen Average
Amgen Average
Water Intake Total Routine Waste
Metric Tons / MM Sq Feet
6 7500
6000
MCM / Sq Feet
4 4500
3000
2
1500
0
0 Average Amgen
Average Amgen
Availability of data allows focus on things that are most impactful
Note: 2009 Pharmaceutical Environmental Group Benchmarking;
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5. Have a Strategy: High Level Direction to
Achieve Awareness, Consensus and Action
Pillars Strategic Direction
• Environmental impacts are understood, managed
and measured for continuous improvement
Conservation
• Supply chain impacts are clearly understood,
measured, and reduced where feasible
• Sustainable products, facilities, and processes
Design for Environment
through use of green design principles
• Amgen reputation enhanced through
communications; publish annual Environmental
Sustainability report
Transparency
• Staff embrace environmental stewardship
• Accurate data collected, available in timely manner
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6. Set Goals: Specific, Measurable,
Attainable, Relevant, Time-Bound
2012 target Results of conservation projects through 2010
Energy Reduce 500,000 GJ Reduction to date: 520,000 GJ Target met
62% of
Carbon dioxide Reduce 75,000 MT Reduction to date: 46,000 MT
target met
Water Reduce 235,000 m3 Reduction to date: 660,000 m3 Target met
62% of
Waste Reduce 700 MT Reduction to date: 435 MT
target met
Recycling Divert more than 40% Reduction to date: 58% Target met
75% of
Fuel efficiency Improve by 4 mpg Reduction to date: 3 mpg
target met
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7. Improve What You Have: Pick the Best
Conservation and Efficiency Opportunities
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8. Pure Water Is Critical to Our Industry
Recycling Significantly Reduces Use
Recycled
water
Reverse osmosis Cooling towers
water treatment
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9. Work with your Utility Partners to
Maximize Benefits
Technical Assistance Programs
• Benchmarking & Energy Audits
– Trane Cube Program
– Data Center Audit
– Building Re-commissioning
• Equipment Efficiency Studies
– Hydraulic Pumps Energy Efficiency Calculated Incentive
– Air Compressors Program (EECIP)
– Boiler Efficiency
– Steam Trap and Condensate Return Analyses
Continuous Energy Improvement
Rebate and Incentive Program Program (CEI)
• Incentivized Projects
– HVAC Airflow Reductions Energy Efficiency Rebates for Business
– Lighting Fixture Upgrades
– Chilled Water Plant Optimization Steam and Condensate Audit
– Pump Efficiency
– High Efficiency Window Film
• Equipment Rebates
– Boiler Economizer Replacement
• Construction/Renovation Incentives
– Energy Saving Measures (From Energy Models)
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10. Our Recycling Program Has a Long
History of Success
• Amgen’s recycling program
has been in place since
mid-1990s
• Since 2007, Amgen has
recycled more than 16,000
MT of waste
Diversion (Recycle) Rate (%)
– 3200 garbage truck loads of
70
recyclable materials
60
50 • Diversion rates continue to
40
increase
30
20 • Waste minimization reduces
10
both purchase and disposal
0
2007 2008 2009 2010 costs
We are recycling more and disposing less…
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11. Plan For the Future: Testing concepts to be
built into Next Generation Laboratories
Fume Hood With ASPS
Fume Hood With ASPS
• Worked with peers in our
industry to develop new
standards for air flow and set
backs
• Tested automated sash
closures that reduce both
energy use and improve safety.
Amgen CONFIDENTIAL Facilities and Engineering
• Integrated occupancy sensors
for lighting and fume hood
control
• Next generation labs – more
automation, more efficient use
of space,
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12. Workplace of the Future Integrates
Sustainability
LEED Registered, Project Tracking to LEED Gold
• Reuse of Existing Core & Shell
• Demolition and Construction Waste
Recycling Program
• Reflective Roofing
• Landscaping 50% More Water Efficient
• Enhanced Commissioning Process
• Active Utility Performance Measurement &
Occupant Engagement Dashboards
• High Performance HVAC, Intelligent Lighting
System (25% Energy Reduction)
• Waterless Urinals / Efficient Water Fixtures
(40% Water Reduction)
• Extensive Daylighting in Workspace,
Exposed and Reflective Ceilings
• Recycled Content & Low Emitting Materials
• Forest Stewardship Council Certified Wood
Highly efficient use of collaborative, tech-enabled space greatly
increases environmental benefits 12 from sustainable building systems.

13. Build sustainability into the core of your
business: Manufacturing of the Future
• Improved productivity - smaller plants and equipment for same results
• Portable, reconfigurable equipment: - improved plant effectiveness
• Isolator technology - reduces size of clean space
• Improved cleanability - reduce energy, water and chemicals
Significantly improves:
• Energy use
• Emissions
• Water usage
• Waste water volume
• Solid waste generation
Advances in technology promise to improve plant efficiency –
both business and environmental performance improvements
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14. Announce Results: Your Stakeholders
Want to Know How You Are Doing
• Customers
– B2B
– Retail
• Neighbors
• Peers
• Shareholders
• Employees
Amgen’s first environmental sustainability report:
http://wwwext.amgen.com/about/environment/espublications.html
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15. Amgen Has Been Recognized For Its
Environmental Sustainability Efforts
• 2010 Waste Reduction Award Program (WRAP)
award was given to Amgen in South San Francisco by
the California Integrated Waste Management Board
• 2010 Puerto Rico Manufacturers Association
Environmental Accomplishment Award, PRMA's
highest honor, awarded to Amgen Puerto Rico for
outstanding and consistent environmental compliance
• 2010 WasteWatch Award was given to Amgen
Thousand Oaks for outstanding achievements in waste
reduction and recycling.
• 2011 U.S. Environmental Protection Agency (EPA)
Environmental Quality Award , presented to Amgen
Puerto Rico; category: business and industry, Region 2
• 2011 Colorado Energy Partner of the Year awarded to
Amgen Colorado for outstanding efforts in making
Colorado a world leader in energy efficiency.
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16. Every Company, At any Scale, Can
Achieve Sustainability Success
 Know where you are
 Have a strategy
 Set goals
 Improve what you have
 Plan for the future
 Build sustainability into the core of your business
 Announce results
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