1. Delivered by Corey B. Schuler, DC, MS, CNS, LN for Emerson Ecologics Product Knowledge Training Restoring Digestive Vitality

2. Optimize digestion Reduce intestinal permeability Support elimination for mild cleansing and detox Re-establish a healthy balance of intestinal microflora Restore Digestive VitalityFour Steps

4. Amylase 32,000 USP

5. Lipase 2,100 FIP

6. Lactase 1,600 ALU

7. Sucrase 300 INVU

8. Maltase 32,100 DPo

9. Phytase 1.7 PU

10. Cellulase 350 CUBecause pH abnormalities may accompany aging in the gut, formulation should have documented activity across a broad pH range. Nat Med J 2010 March;2(3):14–23.

11. Enzyme Activity FCC USP FCC USP FCC FIP FCC III FCC FCC FCC Phytic Acid FCC

12. Enzyme Activity

13. SimilaseProduct Code: SIMIL (90 caps)Product Code: SIMI2 (180 caps) Proprietary digestive enzyme formula active across a broad pH range. High potency, vegetarian formula Broad spectrum activity Relieves occasional gas, bloating, and indigestion. Superior support of carbohydrate, protein, fat, and fiber digestion.

14. Gluten A combination of gliadin and glutenin proteins found in grass-related grains, like wheat, barley, and rye Oatmeal is sometimes linked to gluten intolerance, but the latest consensus is that oatmeal doesn’t contain gluten, but may be contaminated during processing Common in bread, pasta, and cereal Hidden sources Salad dressing Cold cuts Frozen yogurt Toothpaste Gum Envelopes

15. Casein A protein found in dairy products Common in milk, cheese, and yogurt Not same as lactose (milk sugar) Hidden sources Margarine Caramel or butter flavoring Deli meats Jelly beans Some fast food French fries

16. Similase GFCFProduct Code: SIM1 Broad-spectrum enzymes to promote complete digestion of fats, carbohydrates, fiber, and protein Active across a wide pH range Includes Dipeptidyl Peptidase IV (DPP IV) to digest hidden gluten and casein in the diet.

17. Optimize Digestion If pancreatic enzyme support is required, consider: Two-phase, chemical-free combination Hydrochloric acid (e.g., Betaine HCl, Glutamic acid HCl) and/or Pepsin (1:3000) Pancreatin Lipase (2,000–14,000 USP units TID) Amylase (25,000–180,000 USP units TID) Protease (25,000–180,000 USP units TID) Ox bile extract 65–130 mg TID with meals Pancreatic enzymes should be formulated in a delayed-release matrix to prevent deactivation of enzymes by stomach acids.

18. Panplex 8Product Code: PAN66 (60 tabs) High potency pancreatin, an enzyme complex containing protease, amylase, and lipase 8 times stronger than the minimum activity specified by the USP. Helps digest the full range of food types, including fats, carbohydrates and proteins. Formulated for release in the intestines where optimal benefits occur.

19. Panplex 2-PhaseProduct Code: PAN64 (60 tabs) Product Code: PAN65 (180 tabs) Dual-action formula provides support for gastric and intestinal phases of digestion. Phase I support provides hydrochloric acid (HCl), from betaine HCl and L-glutamic acid HCl, and the protein-digesting enzyme, pepsin for release in the stomach. Phase II ingredients include high potency pancreatin and bile salts in a unique, chemical-free delayed-release matrix.

20. Step 2:Support healthy intestinal lining

21. Permeability FactorsProduct Code: PERM4 (90 softgels) Clinically studied nutrients, phospholipids, and essential fatty acids provide nutritional support for intestinal mucosa Contains a high level of glutamine – clinically shown to support healthy intestinal barrier function. Standard of care for many naturopathic physicians Gluten free formula – ideal for those with food sensitivities.

22. RhizinateProduct Code: RHIZIRhizinate Sugarless Product Code: RHIZ4 Rhizinate 3X Product Code: RHIZ45 Glycyrrhizic acid-free formula provides only the beneficial effects of licorice Chewable formula works naturally with enzymes in saliva to support digestive health Best tasting DGL; 3X has delicious German-chocolate flavor Helps relieve stomach discomfort by stimulating and accelerating natural protective factors in the digestive tract Boosts the production of mucin, a natural compound that coats and protects the lining of the stomach and intestines 3X is a potent 10:1 extract; provides immediate benefits and maximum absorption in chewable form. Includes glycine to help keep the stomach lining strong.

23. Step 3: Support elimination for mild cleansing and detox

24. Blue HeronProduct Code: BLU12 (120 caps) Gluten-free blend of dietary fiber, nutritional herbs, and probiotic microflora for convenient, effective, and gentle intestinal support Four unique sources of fiber Flax, psyllium, driedplum, rice bran Soothing GI blend Marshmallow, slippery elm root, fenugreek Detoxification Triphala Microflora support Probiotics Enzymes Papain

25. Step 4: Re-establish a healthy balance of intestinal microflora

26. Effects of Probiotics Probiotics decrease intestinal inflammation and enhance mucosal integrity Normalizes gut permeability Probiotics lessen systemic antigenic exposure and allergic sensitization Non-allergic children have higher concentrations of Lactobacilli and Bifidobacteria Probiotics increase local immune activity IgA, GALT, IFN Probiotics modulate systemic immune activity

27. Viability of commercial preparations Studies have shown low viability of Lactobacilli and Bifidobacteria in unprotected commercial preparations. This has led to the development of various strategies to preserve viability of supplemental probiotics. Immunol Cell Biol. 2000 Feb;78(1):80-8. JDairySci. 2000 Apr;83(4):894-907. Curr Issues IntestMicrobiol. 2004 Mar;5(1):1-8.

28. Inspecting the label CFU = colony forming units High number of CFU does not necessarily indicate a better or more effective product Evaluate genus and species for appropriate applications Evaluate adjunctive ingredients (e.g., lactoferrin, FOS) Number of CFUs should be based on expiration date, not on date of manufacture.

29. What’s important in a Lactobacillus? Adhere to cells Exclude or reduce pathogenic adherence Persist and multiply Produce acids, hydrogen peroxide, and bacteriocins antagonistic to pathogen growth Resist vaginal microbicides, including spermicide Be safe and therefore noninvasive, non-carcinogenic, and nonpathogenic Co-aggregate and form a normal, balanced flora. Appl Environ Microbiol1999;65(9):3763-6.

30. Packaging and Viability “Pick quality packaging and a trusted manufacturer.” “Live bacteria — through the end of shelf life.” “Packaging should ensure an effective level of live bacteria through the ‘best by’ or expiration date.” International Scientific Association for Probiotics and Prebiotics

31. Probiotic Pearls Product Code: PRO74 (30 pearls) Product Code: PRO73 (90 pearls) Provides 1 billion CFU of a blend of Lactobacillus acidophilus and Bifidobacteriumlongum. True Delivery Technology Ensures Active Cultures SURVIVE ARRIVE THRIVE Guaranteed Delivery Shelf-stable No refrigeration required Hardy strains

32. Probiotic Pearls ADVANTAGEProduct Code: PR131 (60 pearls) Provides 5 billion CFU of an exclusive blend of Lactobacillus (L. plantarum,L. acidophilus) and Bifidobacterium (B. lactis, B. longum). True Delivery Technology Ensures Active Cultures SURVIVE ARRIVE THRIVE Guaranteed Delivery Shelf-stable No refrigeration required Hardy strains