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IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS

                             COMPONENT I: BIOCHEMISTRY AND MOLECULAR
                             BIOLOGY delves into gene expression, protein synthesis,
                             energy metabolism and the metabolic pathways associated
                             with diseases.




 GENE EXPRESSION: DNA STRUCTURE, REPLICATION AND EXCHANGE
1.1.1 DNA structure: single- and double-stranded DNA, stabilizing forces, supercoiling
   HGP.pdf
   DNA and Molecular Genetics
   DNA Structure and Analysis
   Gene expression: DNA structure, replication, and exchange
1.1.2 Analysis of DNA: sequencing, restriction analysis, PCR amplification, hybridization
          DNA Sequence Analysis: Introduction
  1.1.3    DNA replication, mutation, repair, degradation, and inactivation
   DNA Synthesis.ppt
   DNA Synthesis. notes
  1.1.4 Gene Structure and Organization; chromosomes, centromere and telomere
   Genes and Gene Organization
   Gene Structure and Genomic Sequence
  1.1.5    Recombination, insertion sequences, transposons
   DNA Recombination
   Insertion Sequences. Notes
   Transposons: Mobile DNA .notes
1.1.6 Mechanisms of genetic exchange: transformation, transduction, conjugation, cross-
over, recombination, linkage
          Genetic Exchange Mechanisms Slides 4-13
            Microbial Genetic Exchange


                       IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
                     COMPONENT I: BIOCHEMISTRY AND MOLECULAR BIOLOGY
1.1.7   Plasmids and bacteriophages
Cells Alive and T4 Bacteriophages
   Introduction to the Bacteriophages T4 Virus
   Inserting a DNA Sample into a Plasmid


 GENE EXPRESSION: TRANSCRIPTION (INCLUDING DEFECTS)
1.2.1 Transcription of DNA into RNA, enzymatic reactions, RNA, RNA degradation
       Dr Chromos School: transcription of DNA into RNA
   Transcription-Synthesis of Messenger RNA (mRNA)
1.2.2 Regulation: cis-regulatory elements, transcription factors, enhancers, promoters, silencers,
repressants, splicing
   Transcription Regulation
   Gene Regulation: Summary Principles and Overview .PDF
 GENE EXPRESSION: TRANSLATION INCLUDING DEFECT
   1.3.1 The genetic code
  Introduction to Bioinformatics
   The Genetic Code
  The Human Genome Project
  Genetic Code Table and the 20 Amino Acids
   DNA-Basics of Structure and Analysis
   1.3.2 Structure and function of tRNA
   Structure and function of transfer RNA
   Transfer RNA
  1.3.3    Structure and function of ribosomes
     Ribosome Structure and Function
  Ribosome Structure and Assembly
   1.3.4 Protein synthesis
  Protein Synthesis Comprehensive
 Protein Synthesis (Animation)
 Protein Synthesis Summary.ppt
   1.3.5    Regulation of translation
 Regulation of Translation. Illus. notes
    Translation.ppt



                        IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
                      COMPONENT I: BIOCHEMISTRY AND MOLECULAR BIOLOGY
1.3.6      Post-translational modifications (phosphorylation, addition of CHO units)
 Post-Translational Modifications
   1.3.7     Protein degradation
   Protein Degradation Resource. notes


 STRUCTURE & FUNCTION OF PROTEINS
    1.4.1 Principles of protein structure and folding
      Protein Structure: The Very Basics .pps
    1.4.2 Enzymes: kinetics, reaction mechanisms
              Symbolism and Terminology in Enzyme Kinetics
              Enzymes and Enzyme Complexes
    1.4.3 Structural and regulatory proteins: ligand binding, self-assembly
    Regulatory Protein Coordinating Gene Expression
   1.4.4 Regulatory properties
Regulation of Enzyme Activity.ppt
Enzyme Regulatory Mechanisms




 ENERGY METABOLISM (METABOLIC SEQUENCES & REGULATION) & DISORDERS
       1.5.1     Generation of energy from carbohydrates, fatty acids, and essential amino acids;
                 glycolysis, pentose phosphate pathway, tricarboxylic acid cycle, ketogenesis,
                 electron transport and oxidative phosphorylation, glycogenolysis
              Step by Step Krebs cycle
           Metabolic Pathways and Energy Production.ppt
           Krebs citric acid cycle
           Energy Production.ppt
        Summary Diagram of the Krebs cycle
        Electron Transport and Oxidative Phosphorylation .pps
       1.5.2     Storage of energy: gluconeogenesis, glycogenesis, fatty acid and triglyceride
                 synthesis
    How Cells Store Energy: ATP. Notes (with Quiz)
    Metabolism and Energy Balance.ppt




                         IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
                       COMPONENT I: BIOCHEMISTRY AND MOLECULAR BIOLOGY
1.5.3 Thermodynamics: free energy, chemical equilibria and group transfer potential,
energetics of ATP and other high-energy compounds
    Energy is conserved: The First Law of Thermodynamics. Notes
    Laws of Thermodynamics


 METABOLIC PATHWAY OF SMALL MOLECULES AND ASSOCIATED DISEASES
    Medical Biochemistry Page IndState-Dr King
       Inborn Errors of Amino Acid Metabolism.html notes
   Biochemical Pathways-Metabolic Pathways-Comprehensive Map
1.6.1 Biosynthesis and degradation of amino acids (eg, homocystinuria)
1.6.2 Biosynthesis and degradation of purine and pyrimidine nucleotides (eg, gout, Lesch-
Nyhan syndrome)
1.6.3 Biosynthesis and degradation of lipids (eg, dyslipidemias, carnitine deficiency,
adrenogenital syndromes)
1.6.4 Biosynthesis and degradation of porphyrins
1.6.5 Biosynthesis and degradation of other macromolecules and associated abnormalities,
complex carbohydrates (eg, lysosomal storage disease), glycoproteins, and proteoglycans
    NetBiochem: Topics, Tables and Still and Animated Graphics
           Biochemistry Pathways Illustrated
           Interactive Concepts in Biochemistry - Interactive Animations




PLEASE REPORT BROKEN LINKS TO DR. CRAY drcray@imhotepvirtualmedsch.com




                      IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS
                    COMPONENT I: BIOCHEMISTRY AND MOLECULAR BIOLOGY

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  • 2. 1.1.7 Plasmids and bacteriophages Cells Alive and T4 Bacteriophages Introduction to the Bacteriophages T4 Virus Inserting a DNA Sample into a Plasmid  GENE EXPRESSION: TRANSCRIPTION (INCLUDING DEFECTS) 1.2.1 Transcription of DNA into RNA, enzymatic reactions, RNA, RNA degradation Dr Chromos School: transcription of DNA into RNA Transcription-Synthesis of Messenger RNA (mRNA) 1.2.2 Regulation: cis-regulatory elements, transcription factors, enhancers, promoters, silencers, repressants, splicing Transcription Regulation Gene Regulation: Summary Principles and Overview .PDF  GENE EXPRESSION: TRANSLATION INCLUDING DEFECT 1.3.1 The genetic code Introduction to Bioinformatics The Genetic Code The Human Genome Project Genetic Code Table and the 20 Amino Acids DNA-Basics of Structure and Analysis 1.3.2 Structure and function of tRNA Structure and function of transfer RNA Transfer RNA 1.3.3 Structure and function of ribosomes Ribosome Structure and Function Ribosome Structure and Assembly 1.3.4 Protein synthesis Protein Synthesis Comprehensive Protein Synthesis (Animation) Protein Synthesis Summary.ppt 1.3.5 Regulation of translation Regulation of Translation. Illus. notes Translation.ppt IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS COMPONENT I: BIOCHEMISTRY AND MOLECULAR BIOLOGY
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  • 4. 1.5.3 Thermodynamics: free energy, chemical equilibria and group transfer potential, energetics of ATP and other high-energy compounds Energy is conserved: The First Law of Thermodynamics. Notes Laws of Thermodynamics  METABOLIC PATHWAY OF SMALL MOLECULES AND ASSOCIATED DISEASES Medical Biochemistry Page IndState-Dr King Inborn Errors of Amino Acid Metabolism.html notes Biochemical Pathways-Metabolic Pathways-Comprehensive Map 1.6.1 Biosynthesis and degradation of amino acids (eg, homocystinuria) 1.6.2 Biosynthesis and degradation of purine and pyrimidine nucleotides (eg, gout, Lesch- Nyhan syndrome) 1.6.3 Biosynthesis and degradation of lipids (eg, dyslipidemias, carnitine deficiency, adrenogenital syndromes) 1.6.4 Biosynthesis and degradation of porphyrins 1.6.5 Biosynthesis and degradation of other macromolecules and associated abnormalities, complex carbohydrates (eg, lysosomal storage disease), glycoproteins, and proteoglycans NetBiochem: Topics, Tables and Still and Animated Graphics Biochemistry Pathways Illustrated Interactive Concepts in Biochemistry - Interactive Animations PLEASE REPORT BROKEN LINKS TO DR. CRAY drcray@imhotepvirtualmedsch.com IVMS BMS GENERAL PRINCIPLES USMLE WEB MAPS COMPONENT I: BIOCHEMISTRY AND MOLECULAR BIOLOGY