1. Dr Hemanth S Naik
Medical Research Scientist

2. INTRODUCTION
• Acute intestinal infection caused by ingestion of food or
water contaminated by a comma-shaped bacteria Vibrio
cholerae
• Deadly water borne disease
• Untreated individuals may die from severe dehydration
within two to three hours.

3. CAUSES
• Vibrio Cholerae
• Exposure from poor hygiene
• Eating raw or undercooked food

4. Signs & Symptoms
• Begin 1 to 3 days after infection
• Abdominal cramps
• Dehydration
– Dry mouth
– Dry skin
– Excessive thirst
– Sunken eyes
– Low urine output
– Low Blood Pressure
• Watery diarrhea with a "fishy" odor
• Tiredness & Unusual sleepiness

5. Sign & symptoms

6. DIAGNOSIS
• Rectal swabs or from fresh stool samples.
• Dark-field microscopic examination of fresh feces
showing rapidly moving bacilli
• All food isolates must be tested for the production of
cholera enterotoxin.

7. TREATMENT
• Water and electrolyte replacement therapy – “oral re-
hydration salts”
• Use of antibiotics

8. PREVENTION
• Drink only boiled water
• Avoid undercooked or raw food
• Proper sanitation

9. HISTORY