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Endoscopic Parathyroid Surgery Danny Yacoub MD George Ferzli MD, FACS Professor of Surgery, SUNY SUNY Downstate Medical Center Lutheran  Medical Center
The Legacy of Ivar Sandstrom (1852–1889)  ,[object Object],[object Object],[object Object],[object Object],I.V. Sandstrom, On new gland in man and several mammals,  Bull Inst Hist Med   6  (1938), pp. 192–222.c
[object Object],[object Object],[object Object],[object Object],I.V. Sandstrom, On new gland in man and several mammals,  Bull Inst Hist Med   6  (1938), pp. 192–222.c The Legacy of Ivar Sandstrom (1852–1889)
The Legacy of Ivar Sandstrom (1852–1889)  I.V. Sandstrom, On new gland in man and several mammals,  Bull Inst Hist Med   6  (1938), pp. 192–222.c
First Parathyroid Surgery ,[object Object],[object Object],Niederle BE etal,  J Am Coll Surg.  2006
Captain Charles Martell ,[object Object],[object Object],O. Cope, The story of hyperparathyroidism at the Massachusetts General Hospital,  N Engl J Med   274  (1966), pp. 1174–1182
Edward Churchill (1895-1972) ,[object Object],[object Object],[object Object],O. Cope, The story of hyperparathyroidism at the Massachusetts General Hospital,  N Engl J Med   274  (1966), pp. 1174–1182 Unfortunately, Martell died soon after due to tetany and complications of nephrolithiasis.
Parathyroid Surgery ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Minimally Invasive Parathyroid Surgery
Why MIVAP? …Cosmetic Results Open surgery scar Minimally invasive / endoscopic scars
Minimally invasive parathyroid surgery: ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Inferior parathyroid release in minimally invasive thyroidectomy
MIVAP-Results
[object Object],[object Object],[object Object],[object Object],[object Object],MIVAP vs Open - Results Miccoli et al., RCT,  Surgery.  2001
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],MIVAP vs Open-Results M. Barczynski et al., World J Surg  2006
Parathyroid Surgery ,[object Object],[object Object],[object Object],[object Object]
Preoperative Imaging ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Parathyroid Locations Possible locations of enlarged parathyroid glands in the neck and  superior mediastinum with the use of an anteroposterior projection (A)  and a lateral projection (B) Udelsman R.  Ann Surg  244:471-479, 2006
Aberrant Parathyroid Locations ,[object Object],[object Object],[object Object],[object Object],Wang CA. Parathyroid re-exploration.  Ann Surg.  1977;186:140–145
Preoperative Parathyroid Localization ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Sestamibi Ectopic Adenoma Hyperplasia
Sonogram / Sestamibi Are additional Localization Studies and Referral indicated for patients with Primary Hyperparathyroidism Who have negative Sestamibi scan results? Elaraj, DM. Sippel, RS. Lindsay S. Sansano I. Duh QY. Clark OH. Kebebew E.  Arch Surg  Vol 145, No 6, 578-581 June 2010. ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intra operative PTH assay. Prospective 361  consecutive patients undergoing minimally invasive  parathyroidectomy. Hwang RS et al.  Ann Surg  2010;251:1122-1126. 1- There is no role for IOPTH for Sestamibi positive patients. 2- It will guide the surgeon in Sestamibi negative / positive sonogram patients: In these cases an inadequate fall in the 10- minute post excision PTH level was highly predictive of multi glandular disease. A Selective  Bayesian approach  to Intraoperative PTH monitoring. A Rising IoPTH Level Immediately after Parathyroid Resection  Are Additional Hyperfunctioning Glands Always Present? An application of the Wisconsin Criteria.  Cook MR et al  Ann Surg   2010;251 1127-1130. 797 consecutive patients. 108 (14%) had a rising ioPTH 5 min after resection of a single parathyroid gland, 36 (33%) continued to have elevated levels and further exploration revealed additional hyperfunctioning glands. In 72 (67%) the ioPTH started to drop within 20 min of gland resection and in all cases correctly predicted operative success. IOPTH / Sonogram
CT Sestamibi Fusion Scan
4D-CT Localization  ,[object Object],[object Object],[object Object],[object Object],Mortenson MM et al. JACS May 2008 Volume 206 No 5 pages 888-895.
CT Guidance
Ultrasound Guidance
MIVAT
Endoscopic Parathyroidectomy  Prerequisite Conditions 1 ,[object Object],[object Object],[object Object]
Patients Eligible for Endoscopic Parathyroidectomy ,[object Object],[object Object],[object Object]
Evaluation for Concomitant Thyroid Nodules and PHPT in Patients Undergoing Parathyroidectomy or Thyroidectomy ,[object Object],[object Object],[object Object],[object Object],Morita S, etal,  Surgery , 2008
Racial Disparity / Double Adenoma Non-African Americans 21 (5.1%) African Americans 14  (12.4%)
Sestamibi and Vitamin D Deficiency ,[object Object],[object Object],[object Object],[object Object],[object Object],Kandil. E. et al  Arch of Otolaryngology , 2008
Adenoma Size and  Biochemical Measurements ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Endoscopic/Conventional Parathyroidectomy ,[object Object],[object Object],[object Object],Jean - Francois Henry Department of Endocrine Suregery, University Hopspital La Timone. Marseilles, France Endoscopic Parathyroidectomy: Why and When ?  World Journal of Surgery  Volume 32 Number 11, November 2008
[object Object],[object Object],[object Object],[object Object],[object Object],Endoscopic/Conventional Parathyroidectomy Jean - Francois Henry Department of Endocrine Suregery, University Hopspital La Timone. Marseilles, France Endoscopic Parathyroidectomy: Why and When ?  World Journal of Surgery  Volume 32 Number 11, November 2008
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Endoscopic/Conventional Parathyroidectomy Jean - Francois Henry Department of Endocrine Suregery, University Hopspital La Timone. Marseilles, France Endoscopic Parathyroidectomy: Why and When ?  World Journal of Surgery  Volume 32 Number 11, November 2008
Endoscopic Parathyroidectomy in the Previously Radiated Neck ,[object Object],[object Object],[object Object],[object Object],Prior Head and Neck Radiation Exposure Is not a Contraindication to Minimally Invasive Parathyroidectomy. Rahbari R. et al JACS Vol210 No 6. 942-948 June 2010.
MIVAP -Technique
 
 
 
 
Bilateral Axillo-Breast (BABA) ,[object Object],[object Object]
Axillary Approach ,[object Object],[object Object],[object Object]
Transaxillary Approach
Robotic Approach Arm 1 Camera Arm 2 Arm 3 This approach was  developed in South Korea by Dr. Woong Chung at Yonsei University College of Medicine in Seoul. He reported his experience with 338 patients
Confidential
 
Confidential
Confidential
Fourth arm trocar External retractor Connected with continuous suction system
Maryland dissector Harmonic curved shears
Confidential
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Endoscopic Parathyroidectomy
Conclusions ,[object Object],[object Object]
Endoscopic Parathyroidectomy ,[object Object],[object Object],[object Object]
Endoscopic Parathyroidectomy ,[object Object],[object Object],[object Object]
Concomitant Thyroid Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Jean - Francois Henry Department of Endocrine Suregery, University Hopspital La Timone. Marseilles, France Endoscopic Parathyroidectomy: Why and When ?  World Journal of Surgery  Volume 32 Number 11, November 2008 Endoscopic/Conventional Parathyroidectomy
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Jean - Francois Henry Department of Endocrine Suregery, University Hopspital La Timone. Marseilles, France Endoscopic Parathyroidectomy: Why and When ?  World Journal of Surgery  Volume 32 Number 11, November 2008 Endoscopic/Conventional Parathyroidectomy

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Endoscopic Parathyroid Surgery

  • 1. Endoscopic Parathyroid Surgery Danny Yacoub MD George Ferzli MD, FACS Professor of Surgery, SUNY SUNY Downstate Medical Center Lutheran Medical Center
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  • 4. The Legacy of Ivar Sandstrom (1852–1889) I.V. Sandstrom, On new gland in man and several mammals, Bull Inst Hist Med 6 (1938), pp. 192–222.c
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  • 10. Why MIVAP? …Cosmetic Results Open surgery scar Minimally invasive / endoscopic scars
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  • 17. Parathyroid Locations Possible locations of enlarged parathyroid glands in the neck and superior mediastinum with the use of an anteroposterior projection (A) and a lateral projection (B) Udelsman R. Ann Surg 244:471-479, 2006
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  • 22. Intra operative PTH assay. Prospective 361 consecutive patients undergoing minimally invasive parathyroidectomy. Hwang RS et al. Ann Surg 2010;251:1122-1126. 1- There is no role for IOPTH for Sestamibi positive patients. 2- It will guide the surgeon in Sestamibi negative / positive sonogram patients: In these cases an inadequate fall in the 10- minute post excision PTH level was highly predictive of multi glandular disease. A Selective Bayesian approach to Intraoperative PTH monitoring. A Rising IoPTH Level Immediately after Parathyroid Resection Are Additional Hyperfunctioning Glands Always Present? An application of the Wisconsin Criteria. Cook MR et al Ann Surg 2010;251 1127-1130. 797 consecutive patients. 108 (14%) had a rising ioPTH 5 min after resection of a single parathyroid gland, 36 (33%) continued to have elevated levels and further exploration revealed additional hyperfunctioning glands. In 72 (67%) the ioPTH started to drop within 20 min of gland resection and in all cases correctly predicted operative success. IOPTH / Sonogram
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  • 27. MIVAT
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  • 31. Racial Disparity / Double Adenoma Non-African Americans 21 (5.1%) African Americans 14 (12.4%)
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  • 46. Robotic Approach Arm 1 Camera Arm 2 Arm 3 This approach was developed in South Korea by Dr. Woong Chung at Yonsei University College of Medicine in Seoul. He reported his experience with 338 patients
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  • 51. Fourth arm trocar External retractor Connected with continuous suction system
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Hinweis der Redaktion

  1. I wound introduce some common scarless approach
  2. A 4~6cm sized vertical skin incision is made in the axilla
  3. The dissection is proceeded using the retractors
  4. To keep a working space, an external retractor is inserted through the skin incision in the axilla and is raised using a lifting device. A second skin incision (0.8cm in length) is made on the medial side of the anterior chest wall for the insertion of the fourth robot arm; apart 2cm superiorly, and 6~8cm medially from the nipple.
  5. Four robotic arms are used for the operation. Three arms are inserted through the axillary incision, the dual channel endoscope is placed on the central arm, and the Harmonic curved shears along with the Maryland dissector is placed on both lateral side arms of the scope. The prograsp forceps is inserted through the anterior chest arm.