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Presented by Dr. Awad Rizk (Mvsc, Ph.D-Tiho-Hannover,Germany) 03.11.2011
Contents  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Overview ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],Definition
Mechanism of action of LA ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
+ + - - + + --  - - + + + + - - Na +   + + + + - - - - Resting (Closed**) Open (brief) inactivated Very slow repolarization in presence of LA LA receptor LA have highest affinity for the inactivated form Refractory period **Closed state may exist in various forms as it moves from resting to open. LA have a high affinity for the different closed forms and may prevent them from opening.
Local analgesia ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],General considerations
Desirable characters of local AA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Local anesthetics ,[object Object],[object Object],[object Object],[object Object],[object Object]
Factors affecting activity and potency ,[object Object],[object Object],[object Object],[object Object]
Pharmacokinetics of local anesthetics ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
C. Metabolism and excretion ,[object Object],[object Object],[object Object],[object Object],[object Object]
Aminoamide metabolism ,[object Object],[object Object],[object Object]
Local anesthetic adjuvants and combinations ,[object Object],[object Object],[object Object]
Effects of vasoconstriction  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Effects on epidural anesthesia ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Local anesthetic toxicity ,[object Object],[object Object],[object Object],[object Object],[object Object]
A. Systemic toxicity ,[object Object]
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Skeletal muscle cont…. ,[object Object],[object Object]
( Cardiovascular system (CVS ,[object Object],[object Object],[object Object],[object Object],[object Object]
B.   Local tissue toxicity ,[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],of local AA   How to avoid toxicity
[object Object],[object Object],[object Object],[object Object],Local anesthetic agents commonly used in vet. practice
[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intravenous lidocaine ,[object Object],[object Object],[object Object]
Physiological effects of intravenous lidocaine ,[object Object],[object Object],[object Object],[object Object],[object Object]
Physiological effects of intravenous lidocaine cont….. ,[object Object],[object Object],[object Object],[object Object]
Clinical use of intravenous lidocaine ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Clinical use of intravenous lidocaine   cont …. ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
Common methods of producing local anesthesia ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Instillation analgesia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Intrasynovial analgesia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
3.Infiltration anesthesia   ,[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Types of infiltration analgesia ,[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],1.linear infiltration
[object Object],[object Object],[object Object],[object Object]
The inverted  red L  is the site of inverted L block and  the green line  is the site of linear infiltration for rumenotomy
[object Object],[object Object],[object Object]
[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Linear infiltration analgesia for rumenotomy
2.Field block analgesia ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object]
The inverted  red L  is the site of inverted L block and  the green line  is the site of linear infiltration for rumenotomy
Inverted-L block..cont…  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Inverted-L block
[object Object],[object Object],3.Ring block
[object Object]
Ring block (olecranon bursitis in buffalo)
(   Ring block (umbilical hernia
Intravenous regional local anesthesia(IVRA) ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IVRA ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
IVRA (teat surgery)
IVRA
IVRA
Local anesthesia for standing laparotomy in cattle ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
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Local analgesia in animals_ Dr. Awad Rizk

  • 1. Presented by Dr. Awad Rizk (Mvsc, Ph.D-Tiho-Hannover,Germany) 03.11.2011
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  • 9. + + - - + + -- - - + + + + - - Na + + + + + - - - - Resting (Closed**) Open (brief) inactivated Very slow repolarization in presence of LA LA receptor LA have highest affinity for the inactivated form Refractory period **Closed state may exist in various forms as it moves from resting to open. LA have a high affinity for the different closed forms and may prevent them from opening.
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  • 66. The inverted red L is the site of inverted L block and the green line is the site of linear infiltration for rumenotomy
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  • 74. The inverted red L is the site of inverted L block and the green line is the site of linear infiltration for rumenotomy
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  • 79. Ring block (olecranon bursitis in buffalo)
  • 80. ( Ring block (umbilical hernia
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  • 85. IVRA
  • 86. IVRA
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  • 88. Do you have any questions???