Opioids

Opioids (Narcotics) “ Among the remedies which it has pleased Almighty God to give to man to relieve his sufferings, none is so universal and so efficacious as opium.”

Ancient History ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Opioids (God Morpheus of Dreams) Narcotics (Narcosis—stupor) ,[object Object],[object Object]

Pain Neuro Transmitters Pain Relief Meds ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Body’s Natural Analgesia ,[object Object],[object Object],[object Object],[object Object],[object Object]

Opioid Distribution in the Brain

Location and time course of pain evoked neural activity in human subjects

PET Scans show endogenous opioid activation during sustained pain

Opioid Clinical Indications ,[object Object],[object Object],[object Object],[object Object],[object Object]

Pharmacologic Types of Opiates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Drugs Methods of Use ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Oxycontin Abuse ,[object Object],[object Object],[object Object]

Common Opioid Side Effects ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Symptoms of Use ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Reinforcing Pharmacologic Properties ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Additive Toxicity Issues ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Acute Opioid Overdose ,[object Object],[object Object],[object Object],[object Object],[object Object]

Opioid Antagonists ,[object Object],[object Object],[object Object],[object Object],[object Object]

Abstinence or Withdrawal Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object]

Abstinence Syndrome ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Non-Opioid Withdrawal Treatments ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Methadone ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Additional Agonist Analgesics Use For Maintenance ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Pain Syndromes ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

ABC’s of Pain Management Assess pain regulary Believe patients & their families in their reports of pain Choose interventions appropriately Deliver these in a timely fashion Enable/Empower patients & Families to overcome pain no pain mild discomforting horrible excruciating

Non-Drug Pain Management Techniques ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Analgesic Ladder ,[object Object],[object Object],[object Object],[object Object],Strong opioid (Morphine) with adjuvant analgesic

PCA (patient-controlled analgesia pump)

Opioids

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Opioids