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Muscle Contraction: Sliding Filament Theory
Sliding Filament Theory Muscle contraction occurs by a sliding filament mechanism whereby the sarcomeres shorten (the Z-lines come closer together) by the action of the actin filaments sliding over the myosin filaments. Myosin filaments may look somewhat like a golf club but they are not inflexible. In fact, muscle contraction would be impossible if the myosin molecules did not have a "hinge" along the shaft that allows for a ratchet movement of the head. The force behind muscle contraction is the ratchet movement of  these tiny myosin heads toward the center of their sarcomere. This ratchet movement occurs many times during a muscle contraction. Electron microscopy combined with chemical experiments show that muscle is composed of 2 contractile proteins:  a) Thin filaments: actin, attached to Z line, found in both A and I bands  b) Thick filaments: myosin, found in A band
When muscle contracts the actin filaments slide into the A band, overlapping with myosin. When muscle contracts:   a) the Z lines move closer together   b) the I band becomes shorter       c) the A band stays at the same length This is called the "sliding filament" model of muscle contraction.  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object],[object Object],[object Object]
Role of Calcium ion and Energy Source (ATP)
Role of Calcium ions ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Role of the energy source (ATP) ,[object Object],[object Object],[object Object]
[object Object],[object Object]
Role of Motor Units
Role of motor units ,[object Object],[object Object],[object Object]
[object Object],[object Object],[object Object]

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Bio

  • 1. Muscle Contraction: Sliding Filament Theory
  • 2. Sliding Filament Theory Muscle contraction occurs by a sliding filament mechanism whereby the sarcomeres shorten (the Z-lines come closer together) by the action of the actin filaments sliding over the myosin filaments. Myosin filaments may look somewhat like a golf club but they are not inflexible. In fact, muscle contraction would be impossible if the myosin molecules did not have a "hinge" along the shaft that allows for a ratchet movement of the head. The force behind muscle contraction is the ratchet movement of  these tiny myosin heads toward the center of their sarcomere. This ratchet movement occurs many times during a muscle contraction. Electron microscopy combined with chemical experiments show that muscle is composed of 2 contractile proteins: a) Thin filaments: actin, attached to Z line, found in both A and I bands b) Thick filaments: myosin, found in A band
  • 3.
  • 4.
  • 5.
  • 6. Role of Calcium ion and Energy Source (ATP)
  • 7.
  • 8.
  • 9.
  • 10.
  • 11. Role of Motor Units
  • 12.
  • 13.