Session Four: Exploring the financial mechanisms that can be harnessed to increase investment in
dementia.
Mr. George Vradenburg, Convenor, The Global CEO Initiative on Alzheimer's and Chairman of USAgainstAlzheimer’s & World Dementia Council Member
2. Mobilizing the Needed Resources
Increasing our Productivity
Increasing Investor
Reward/Reducing their Risk
Innovative Finance Mechanisms
and Approaches
2
3. Increasing our Productivity
Global Alzheimer’s Platform
3Examples only, not comprehensive
U.K.
Dementia
Platform
Global Goals: Longitudinal Data, Biomarkers/Diagnostics, New Targets,
Reduce Time/Cost to Market, Regulatory Alignment
4. Increasing Investor
Reward/Reducing Risk
4
Mechanism Example
Reward: Extension of
Exclusivity/IP Period
Orphan Drug Policy Changes
Risk: Shortening
Development Times
HIV/AIDS; Biomarkers +
Conditional Approval; Trial-
Ready Infrastructure
Both: Reduce Uncertainty Accelerated and Globally
Aligned Regulatory Pathways
►Here are mechanisms to change the risk/reward
equation
►Each has been done elsewhere; we can do it
8. THANK YOU
8
Maike Stenull, Johnson & Johnson
Luc Truyen, Janssen (a Johnson & Johnson Company)
Cynthia Duggan, New York Academy of Sciences
The Member Companies of
The Global CEO Initiative on Alzheimer’s