2. 10 Facts about
Lamellar Ichthyosis
Dr Miriam Kinai
DarkSkinDermatology.c
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3. 1. Lamellar ichthyosis
is a keratinization
disorder.
2. Lamellar ichthyosis
is usually inherited in
an autosomal
recessive fashion.
4. 3. The incidence of
Lamellar ichthyois in
males and females is
equal.
4. Patients with
lamellar ichthyosis
have a proliferative
hyperkeratosis.
5. 5. Lamellar ichthyosis
type 1 is associated
with transglutaminase
1 (TGM 1) gene
mutation.
6. Babies with Lamellar
ichthyosis are born
covered in a collodion
7. 7. The collodion
membrane is shed
within 2 weeks to
reveal red, scaly skin.
8. The scales cover the
entire body and do not
spare the joints.
8. 8. The scales of
Lamellar ichthyosis are
usually larger, darker
and more adherent
than those of other
types of ichthyosis.
9. The scales are
arranged in a mosaic
11. Adapted from Lamellar
Ichtyosis by Dr Miriam
Kinai which uses
color pictures and clear
explanations to teach
about this skin
disorder.
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