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Stem Cell research &
Ethics Workshop
An overview of Debating Science Issues
An introduction to the Science of Stem Cells
Hope or Hype?  You decide….
What is Debating Science Issues?


• All‐Ireland Secondary School Debate 
  competition
• Open to senior cycle students
• All debates are on biomedical science
• Sponsored by the Wellcome Trust
Why Debating Science Issues?

• Encourage you to take an active 
  interest in biomedical science 
  research occuring in Ireland and 
  its ethical implications for all of 
  society
• Encourage you to consider the 
  many diverse career options 
  available in science in Ireland
DSI topics
• Stem cell research
• Nanotechnology
• Genetically modified foods
• Health & Self‐testing kits
• Vaccinations
• Animal testing
Organization of  DSI
• Small groups take part in round table 
  ethical workshops to prepare for first 
  round of debates
• Students work as a team under 
  teacher supervision to prepare 
  debates
• 3‐4 provincial heats (if successful!) 
  before All‐Ireland Semi‐final and 
  Final at The Science Gallery in Trinity 
  College in April 2010
• Independent research‐funding    
      charity
• Largest charity in the U.K.
• Established in 1936
• Founder of company that 
    developed AZT and Rubella       
      vaccines
• Interests range from science to 
      history of medicine
Science Foundation Ireland
• REMEDI is one of ten centres of excellence 
  in Ireland funded by the Science Foundation 
  Ireland and dedicated to advancing 
  Ireland’s smart economy through cutting‐
  edge research and development. Forging 
  innovative partnerships with industry, 
  government and academia, the centres add 
  value to Ireland through job creation, 
  inward investment and international 
  excellence in science, engineering and 
  technology.
Stem Cell science‐
What are stem cells?
• Unspecialised cells lacking any 
  tissue‐specific structure
• Can give rise to specialised cells 
  through the process of 
  differentiation
Where are stem cells found?
• Embryonic stem cells (pre‐birth)

• Adult stem cells (post‐birth)
     Umbilical cord blood
     Brain
     Olfactory (nasal passages) tissue
     Bone marrow
     Adipose (fat) tissue
     Other sources are being discovered….
Sources of embryonic stem cells

• Spare or surplus embryos from 
  in vitro fertilisation (IVF)
• Embryos created for scientific 
  research using donated eggs and 
  sperm  
• Embryos created for scientific 
  research using therapeutic 
  cloning
THE DEBATE

  In Ireland, the debate over whether we allow 
  embryonic stem cell research is in its infancy.
  This requires mutual respect for opposing 
  positions and continued dialogue.
  We need a proper understanding of the 
  scientific facts about development of the 
  embryo and what is involved in embryonic 
  stem cell research.
  We must think through our ethical principles 
  and their implications.
Thank You

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