IBD

Inflammatory Bowel Disease Crystal M. Byerly, PA-C Seton Hill University PA Program Grant from Centocor, Inc.

Learning Objectives ,[object Object],[object Object],[object Object],[object Object]

Inflammatory Bowel Disease ,[object Object],[object Object]

IBD = Crohn’s Disease and Ulcerative Colitis ,[object Object],[object Object]

[object Object],[object Object]

Ulcerative Colitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Ulcerative Colitis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Ulcerative Colitis ,[object Object],[object Object],[object Object]

Classifications of UC Severity ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Complications of Severe UC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Crohn’s Three Main Patterns of Distribution ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Crohn’s Disease ,[object Object],[object Object],[object Object]

Crohn’s Disease Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Crohn’s Disease ,[object Object],[object Object],[object Object],[object Object]

Crohn’s Complications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Extraintestinal manifestations of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Genetics of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]

ColoRectal Cancer and IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]

Differential Diagnosis of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Current Diagnostic Tools for Initial IBD Diagnosis ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

There is no ONE single test to dx IBD. ,[object Object],[object Object],[object Object],[object Object]

Common Bloodwork in diagnosing IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]

Differentiating type of IBD Sandborn WJ et al, Inflamm Bowel Dis 2001;7:192-201 Peeters M et al, AM J Gastroenterology 2001; 96:730-4 LAB TEST SENSITIVITY SPECIFICITY TYPE IBD + pANCA 50-65% 85-92% UC +ASCA 55-61% 88-95% CROHN’S +pANCA & ASCA - 44-57% 81-97% UC -pANCA & ASCA+ 38-56% 94-97% CROHN’S

Immune Markers being studied for diagnosing IBD ,[object Object],[object Object],[object Object],[object Object],[object Object]

IBD Management ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Acute Management of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Chronic Therapy of IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Corticosteroids ,[object Object],[object Object],[object Object],[object Object],[object Object]

Cyclosporine ,[object Object],[object Object],[object Object],[object Object]

Mesalamines: 5-ASA/Aminosalicylates ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Mesalamines continued ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Thiopurines ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Methotrexate ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Biologic Therapy –vs- Conventional Therapy in IBD ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Biologic Therapy with CD ,[object Object]

Biologic Therapy ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Adalimumab ,[object Object],[object Object],[object Object]

Combination Therapy for Crohn’s ,[object Object],[object Object],[object Object],[object Object],[object Object]

Biologic therapy with UC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Crohn’s Surgery ,[object Object],[object Object],[object Object],[object Object]

Surgical Therapies with Fistula ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Ileal Resection in Crohn’s Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Post-Op Recurrence of CD ,[object Object],[object Object],[object Object],[object Object]

Ulcerative Colitis Surgery Indications ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Surgery types with UC ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]

Conclusion Review of Learning Objectives ,[object Object],[object Object],[object Object],[object Object]

IBD

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IBD