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Lesson 8: Dementia and Alzheimers Disease




Sunday, 31 March 13
Question from Lesson 7

  Some people think that age-related memory decline is inevitable
  and applies to all forms of memory. Are these people correct?
  Provide reasons for your answers.




Sunday, 31 March 13
Question from Lesson 7

  Some people think that age-related memory decline is inevitable
  and applies to all forms of memory. Are these people correct?
  Provide reasons for your answers.


 Older people Do take longer to learn new information

 STM – Depends on the task, easy one part tasks are ok. Tasks
 that require divided attention are challenging for older people.

 LTM - Episodic down, Procedural same, Semantic Same



Sunday, 31 March 13
Dementia
Large group of neurodegenerative diseases that cause a
decline in mental functioning.
                             Dementia develops
                             progressively with loss of
                             memory an initial onset
                             symptom




Sunday, 31 March 13
Alzheimer’s Disease
• The most common form of dementia
• Accounts for 50 – 70% of dementia
• Neurodegenerative disease that causes wide spread cell
     death
•    Causes decline in all aspects of cognitive function
•    Post-mortems reveal deposits of plaque along the
     damaged synapses
•    These plaques and tangles effect neural transmission




Sunday, 31 March 13
Alzheimer’s Disease


•    100,000 Australians effected
•    1 in 25 over 60
•    1 in 8 over 80
•    No simple diagnostic test – really only know for sure
     when post-mortem conducted
•    Symptoms are different for each person further
     complicating diagnosis




Sunday, 31 March 13
Alzheimer’s Disease




Sunday, 31 March 13
Alzheimer’s Disease - symptoms


  Typical memory loss includes
  • Events
  • Words and names
  • Written and verbal directions
  • Stories, TV, Movies, Books
  • Semantic memory decline
  • Procedural memories
  Personality changes can also occur..........



Sunday, 31 March 13
Alzheimer’s Disease – Post-mortem


•    Show high levels of the protein Amyloid
•    Highly toxic – causes cell death
•    Causes the development of the plaques and tangles
•    Brains also have a massive lack of acetylcholine (an
     important neurotransmitter)


    Why are you in my brain amy loid??? She likes to play
    twister and tangle things up. Doesn’t brush her teeth
    and leaves Plaque everywhere! She drinks all the
    acetylcholine mouthwash

Sunday, 31 March 13
Alzheimer’s Disease - a race to the cure




Sunday, 31 March 13

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Lesson 8 dementia and alzheimer's disease 2013

  • 1. Lesson 8: Dementia and Alzheimers Disease Sunday, 31 March 13
  • 2. Question from Lesson 7 Some people think that age-related memory decline is inevitable and applies to all forms of memory. Are these people correct? Provide reasons for your answers. Sunday, 31 March 13
  • 3. Question from Lesson 7 Some people think that age-related memory decline is inevitable and applies to all forms of memory. Are these people correct? Provide reasons for your answers. Older people Do take longer to learn new information STM – Depends on the task, easy one part tasks are ok. Tasks that require divided attention are challenging for older people. LTM - Episodic down, Procedural same, Semantic Same Sunday, 31 March 13
  • 4. Dementia Large group of neurodegenerative diseases that cause a decline in mental functioning. Dementia develops progressively with loss of memory an initial onset symptom Sunday, 31 March 13
  • 5. Alzheimer’s Disease • The most common form of dementia • Accounts for 50 – 70% of dementia • Neurodegenerative disease that causes wide spread cell death • Causes decline in all aspects of cognitive function • Post-mortems reveal deposits of plaque along the damaged synapses • These plaques and tangles effect neural transmission Sunday, 31 March 13
  • 6. Alzheimer’s Disease • 100,000 Australians effected • 1 in 25 over 60 • 1 in 8 over 80 • No simple diagnostic test – really only know for sure when post-mortem conducted • Symptoms are different for each person further complicating diagnosis Sunday, 31 March 13
  • 8. Alzheimer’s Disease - symptoms Typical memory loss includes • Events • Words and names • Written and verbal directions • Stories, TV, Movies, Books • Semantic memory decline • Procedural memories Personality changes can also occur.......... Sunday, 31 March 13
  • 9. Alzheimer’s Disease – Post-mortem • Show high levels of the protein Amyloid • Highly toxic – causes cell death • Causes the development of the plaques and tangles • Brains also have a massive lack of acetylcholine (an important neurotransmitter) Why are you in my brain amy loid??? She likes to play twister and tangle things up. Doesn’t brush her teeth and leaves Plaque everywhere! She drinks all the acetylcholine mouthwash Sunday, 31 March 13
  • 10. Alzheimer’s Disease - a race to the cure Sunday, 31 March 13