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Celebrating a
 100 Year
  Legac Y of InnovatIon
Although only recently accepted into the international food lexicon, umami, the fifth taste
                                            stretches back into the annals of food history. Many popular foods and seasonings evoke


    In the
                                            the umami taste, although it remained unidentified in a scientific sense.




    By Jeanne turner                            A fermented or pickled fish sauce called garum, rich in umami taste and char-
                                            acteristics, is one of the earliest recorded flavoring agents used in ancient Greece
                                            and Rome when Aristotle identified seven basic tastes: sweet, salty, sour, bitter, spicy,
                                            astringent and sandy. Chinese records from as early as 1,000 B.C. documented five tastes.
                                            Other ancient cultures also record more than four basic tastes.

    Dashi ingredients from left to right:
    Kombu (kelp);
    Katsuobushi (Dried bonito);
    Niboshi (Small dried fish);
    Dried Shiitake mushroom;
    Water


2
                                                 Apparently the ideas of a different Greek philosopher, Democritus, held greater power
                                            than Aristotle’s, as his identification of four basic tastes—sweet, salty, sour and bitter—
                                            became the world’s standard for almost 2,500 years. As modern science progressed in the
                                            early nineteenth century, giving us a better understanding of the human body with micro-
                                            scopic views of the tongue and taste buds, all evidence appeared to confirm the existence
                                            of just four different taste receptors.
                                                 In 1903 the renowned French chef, Auguste Escoffier, published a cookbook including
                                            his original creation, veal stock, suggesting a fifth taste was responsible for the delicious
                                            flavor of this culinary masterpiece. But his assertions went no further at that time.
                                                 In fact, among culinary treasures to emerge in the last century, perhaps none has had a great-
                                            er impact on the global community than umami—so complex it almost defies description, yet
     the H I S T O R Y




                                            so universal it is a wonder its secrets remained hidden for so long. Throughout the world, every
                                            culture can identify indigenous sources of umami. Nordic lands have anchovies, cod roe paste
                                            and dried fish. In South America and the Caribbean, dried shrimp improve the taste of soups,
                                            stews and rice dishes. Tomatoes, another source of umami, are native to Peru and Ecuador.
                                                 What was the key that unlocked umami’s secret once and for all? It came in 1908 from
                                            yet another culture familiar with savory sensations that formed the backdrop to traditional
                                            dishes, as a Tokyo University professor decided to investigate the scientific explanation for
                                            the intriguing taste of dashi.
The Root of Umami Discovery
resIdents of an IsLand                          distinctive that a good dashi helps reduce      seaweed that helps lend dashi its distinc-
nation, the Japanese people resourcefully       the need for salt and oil and helps create      tive umami profile, has the highest natural
use the bounty the sea provides to enhance      healthier nutritional profiles.                 levels of glutamate in the world.
and enrich their cuisine. Not only do cer-          Seasonality also plays an important             Umami can be described as the savory
tain foods and ingredients play a role in the   role in Japanese culture and cuisine. The       taste imparted by glutamate and five
daily diet, they also have such an ancient      garnishes selected, the food presentation,      ribonucleotides, including inosinate and
heritage that they are interwoven into the      even the dishes chosen to serve the food        guanylate, identified in 1913 and 1957
history of Japanese culture. The best ex-       are selected for their seasonal suitability,    respectively, which occur naturally in
ample of this is dashi, a carefully prepared    and food or ingredients used in their proper    many foods, including meat, fish, certain
stock that forms the basis for multiple         season are said to be in “shun.” This focus     vegetables and dairy products. Another
                                                                                                nucleotide, adenylate, identified in the
                                                                                                1960s, is abundant in fish and shellfish.
                                                                                                    While the Japanese have enjoyed the
                                                                                                benefits of umami in their cuisine for cen-
                                                                                                turies, the Western world only recently em-
                                                                                                braced the concept of umami. Professional
                                                                                                chefs in the West now experiment with the
                                                                                                types of ingredients that give the distinctive
                                                                                                umami signature to a prepared meal.
                                                                                                                                                   3
dishes within Japanese cuisine.                 on seasonality portrays the link between            Further research in the 1980s solidi-
    Dashi is a deceptively simple stock cre-    nature and food that is deeply ingrained        fied umami’s acceptance as the fifth taste
ated using carefully dried and prepared in-     within Japanese cooking. Dashi might serve      in the international lexicon. Umami
gredients. Dashi relies upon the combina-       as the basis for various popular dishes eaten   acts synergistically with other flavors
tion of kombu, or dried kelp seaweed, and       in season, with winter dishes such as Pork      to enhance and amplify their effect, to
katsuobushi, or dried bonito flakes, mixed      and Miso Soup (Tonjiru) or Simmered             bring out the full boldness and richness
with other ingredients as distinctive as the    Daikon Radish; or summer dishes such            of the entire formulation for a heightened
chef who prepares his or her own unique         as Grilled eggplant in dashi, or Somen, a       gastronomic experience.
variety. The kombu and katsuobushi are          wheat noodle served with dipping sauce.             In addition to its role as a palate pleaser,
carefully selected, aged and dried.                 In 1908, Professor Kikunae Ikeda of         umami is beneficial for human survival
    Whereas a Western bouillon might            Tokyo Imperial University drilled down          in the most primal sense. Each of the five
simmer any number of fresh ingredients          to the bare essence of dashi’s ingredients      tastes recognized by the human body has
for hours in a reduction, the dried dashi       and identified a taste that could not be        a special role to play. Historically, the tastes
ingredients are soaked in water or heated       explained by any of the four traditional        either encourage us to pursue the proper
only briefly to extract the bare essence of     tastes—sweet, salty, sour, bitter—or any        nourishment for survival or warn us away
flavor. Steeping the ingredients in hot water   combination of the four. Dr. Ikeda’s investi-   from harmful foods. For example, we
allows the amino acids to infuse the broth,     gations led him to L-glutamate, the source      desire sweet foods to help maintain enough
as amino acids are the basis of the stock’s     of this taste, and he named the taste itself    calories in our body and salty foods to help
unique taste. This taste is so rich and         “umami.” In fact, kombu, the dried kelp         us maintain a proper mineral                  
Thai Salad




    balance. Many sour or bitter foods were
    poisonous or dangerous to humans, so
    those two tastes acted as a warning.
4
         Our preference for and delight in
    foods with umami taste helps us
    ensure we consume the proper
    amount of amino acids for our
    bodily needs, which include,
    among many other functions, the                     Atsukezuri, Katsuobushi shavings
    right amount and type of proteins
    to help rebuild muscle tissue after
    exertion or exercise.
         But if you talk to chefs or other
    experts, they say a key characteristic
    of umami is to make your mouth
    water. Closely associated with foods in
    season that are ripened or matured, umami
    is a taste that reaches its best potential   Miso
    through foods served at the peak of matu-
    rity to help promote good health. As foods
    ripen or mature, the amino acid content
                                                                                 Dashi
    increases, enhancing the umami effect.
When Science Meets
Culinary Arts

                    G
                                 lutamate, otherwise known as L-glutamate or monosodium glutamate
                                 (MSG), identified as the key amino acid responsible for umami flavor, is
                                 not exclusive to kombu. It is also common in Western ingredients with
                                 savory flavor, such as Parmesan cheese, asparagus, tomatoes, meat and
                                 anchovies (which NPR science writer Jonah Lehrer termed “glutamate
                                 speedballs”). Upon further investigation, research confirmed that these
                                 foods could also be included under the description of umami with respect
                    to their amino acid profile. This could be one reason why, once Western chefs grasped
                    the implications of umami, it took the culinary world by storm—it was always present
                                                                    yet unidentified; once acknowledged, it
                                                                    allowed for discovery of savory food cat-
                                                                    egories containing the essence of umami
                                                                    that could enhance fine cuisine.
                                                                         Just as with the other four basic tastes,
                                                                    the tongue has taste receptors that are
                                                                    tuned into umami. Scientific studies in
                                                                    recent years have also shown that the
                                                                    stomach contains glutamate receptors,
                                                                    and that the amino acid glutamate plays an
                                                                    important role in food digestion.
                                                                         Molecular gastronomy examines the
                                                                    link between the physical and chemical
                                                                    processes that occur during cooking and
                                                                    is becoming a focus of attention among
                                                                    chefs, researchers and food writers world-
                                                                    wide. It connects the scientific explanation
                                                                    for food or ingredient behavior with the
                                                                                                                     5
                                                                    social, artistic and technical components
                                                                    of culinary processes. Some examples of
                                                                    the types of issues examined via molecular
                                                                    gastronomy might include the study of
                                                                    how various ingredients change depen-
                                                                    dent upon different cooking methods, and
                                                                    investigation into the question:
                                                                         Can we devise new cooking methods
                                                                    that produce unusual and improved results
                                                                    of texture and flavor?
                                                                         As science continues to join forces with
the S C I E N C E




                                                                    the culinary arts, Ajinomoto Company
                                                                    Inc. is committed to assisting with the
                                                                    development of healthier foods enhanced
                                                                    with umami-based ingredients, to not only
                                                                    help create better tasting food but to help
                                                                    develop a healthier population as well.
The 21st Century –
    “The Century of Amino Acids”
    amIno acIds, whIch most                             in and essential to the human body. Water        mapped out our DNA genetic make up
    scientists acknowledge as the building              accounts for approximately 60% of our body       while the next project is determining the
    blocks of life, are critical to life and function   weight, followed by amino acids (proteins),      proteome, or the make up of all the proteins
    in a wide variety of ways in multiple indus-        constituting 20%. Amino acids perform vari-      that exist in the human body. Scientists
    tries and within the human body, including          ous important functions and make up vital        suspected there were between 10,000 or
    activity related to flavoring, nutritional func-    body tissues such as muscles, the gastroin-      20,000 proteins; now they admit they don’t
    tion, physiological well being, and reactivity.     testinal tract, internal organs, hemoglobin      even know the final number.”
         Amino acid-based ingredients provide a         contained in red blood cells, and collagen,           Amino acids play a role in areas as di-
    wide range of tastes or benefits to foods, such     the main component of our hair and skin.         verse as seasonings, pharmaceuticals, nutri-
    as umami or sweet taste sensations supplied             Athletes were among the first to discover    tional supplements, cosmetics, fertilizers and
    by monosodium glutamate and aspartame               and use amino acid-based foods and ingre-        livestock feed. Some scientists and humani-
                                                        dients to help rebuild muscle during or after    tarians believe amino acids hold the key to
                                                                 a workout. Science confirmed that       helping solve the global issue of malnutrition
                                                                  the human body during exercise and     due to inadequate protein intake. Amino
                                                                  recovery utilizes most rapidly pro-    acid fortification is a cost-effective, highly
                                                                  teins that have a certain amino acid   bioavailable method of maximizing limited
                                                                  composition, specifically branched-    food supplies. Ajinomoto Group also utilizes
                                                                  chain amino acids (BCAAs such          the nutrient-rich byproduct generated dur-
                                                                  as valine, leucine, and isoleucine),   ing amino acid production to convert food
                                                                  which promote the protein synthesis    supplies into valuable coproducts such as
                                                                  of skeletal muscles.                   fertilizer or feed, which reduces the waste
                                                                      Despite scientific advances,       stream and helps preserve our ecosystem.
                                                                  lately the research community has           Overall, research proves that essential
                                                                  discovered it has barely scratched     amino acids are necessary for proper bodily
                                                                  the surface of the vast universe of    function and nutritional balance. The Aji-
    respectively. In this capacity, amino                         amino acids and proteins that exist    nomoto Group believes that amino acids
    acid-based ingredients help enhance                           within the human body, or their        hold the key to future development of food,
6
    or highlight the natural flavors of other              functions. “We have between 100,000           nutritional products and pharmaceuticals.
    ingredients, foods and seasonings while             or more different proteins that make our         Ajinomoto will continue to be the world’s
    remaining in the background.                        bodies function properly,” said Jack Heaton,     premier company committed to providing
        Far from being obscure synthetic sub-           president of Ajinomoto Scientific Group,         better health, nutrition and quality of life
    stances, amino acids are naturally present          LLC, Raleigh, N.C. “The genome project           through amino acid creation and utilization.



                     1908                               1956                                             1963
                  dr. Kikunae Ikeda                     ajinomoto U.s.a., Inc.,                          ajinomoto concludes tie-up
                  obtains patent                        formally established                             with cPc International Inc.
                  to produce                                                                             (presently Unilever Bestfoods)
                  L-glutamate                              1956
    as the source of ‘umami.’                              ajinomoto do Brazil Industria                 1968
                                                           e comercio, s.a established                   ajinomoto del Peru s.a. established
    1909
    aji-no-moto, the product,                               1962                                         1973
    is launched as umami                                    ajinomoto concludes tie-up                   ajinomoto concludes tie-up with
    seasoning based on                                      with Kellogg company                         general foods corporation;
    glutamate.                                                                                           reincorporated in Japan as ajinomoto
                                                                                                         general foods, Inc.
Sweeeeettttt!!!!
sImILar to BUILdIng BLocKs,                     populations such as diabetics a great deal      human body metabolizes all essential ami-
which in multiple permutations can create       of variety and flexibility in budgeting total   no acids in the same way. When a person
myriad structures, amino acids in various       carbohydrate intake without affecting           consumes aspartame, the body breaks it
molecular combinations can create an            blood sugar. And with an increased focus        down into aspartic acid, phenylalanine and
astonishing variety of food ingredients. The    on obesity within the general population,       a small amount of methanol, identical to
same substance that creates the unique          aspartame can help tame weight manage-          that found naturally in pectin-containing
savory taste of umami is also responsible, in   ment issues by enabling product develop-        food products. The rest of the diet provides
a different form, for mimicking the unique      ers to create foods with a sweet profile        much greater quantities of
taste of sugar.                                 yet reduced calorie count compared to a         these components than
     Aspartame is approximately 200 times       sugar-sweetened counterpart.                    does aspartame.
sweeter than sugar, which means that 200             From frozen novelties to hard candies
kg of sugar can be replaced with 1 kg of as-    to iced tea, cocoa mixes and carbonated
partame. Aspartame has an energy value of       soft drinks, aspartame enhances the
4 calories per gram but, because only min-      eating experience of consumers world-
ute amounts of aspartame are required to        wide without adding to
provide the equivalent sweetness of sugar,      the waistline.
it can reduce a product’s calorie content by
up to 99%. It offers excellent solubility and
is suitable for most product applications
within a certain pH and temperature range.
Aspartame is utilized as a stable sweetener         Aspartame is a dipeptide
in products ranging from homogenized            composed of two amino acids:
dairy foods to beverages, frozen desserts,      L-aspartic acid and L-phenylalanine.
confections, baked goods, cereals and fruit     Phenylanine is an essential amino
preserves. In addition, aspartame can in-       acid, considered essential for
tensify and extend fruit flavors in foods and   proper bodily function and
beverages. For example, aspartame makes         good health. Many com-
                                                                                                                                               7
chewing gum taste sweet up to four times        mon foods, such as
longer than gum sweetened with sugar.           meat, cheese, fish,
     Aspartame does not promote tooth           vegetables or fruit,
decay and is an FDA-approved, safe              also contain these
sweetening agent, and thus offers special       constituents, and the



1974                                            1980                                            1982
eUroLYsIne s.a. established                     ajinomoto danone co., Ltd.                      ajinomoto opens pharmaceutical-
in france                                       established (presently calpis                   grade L-amino acid manufacturing
                                                ajinomoto danone co., Ltd.)                     plant in raleigh, n.c.
1974
ajinomoto Interamericana Industria e                             1981                           1983
comercio Ltda. established in Brazil                             aspartame available            nutrasweet ag established in
                                                                 for tabletop use               switzerland (presently ajinomoto
1975                                                                                            sweeteners europe)
nissin-ajinomoto alimentos Ltda.
established
A Look Ahead
    the scIentIfIc dIscoverY                            Just as amino acids are the building      ment, they also will live well, or live better,
    of glutamate as the basis for umami taste       blocks for so many unique and diverse         and it is our goal to help them achieve this
    and the foundation of Ajinomoto oc-             products, they also form the platform for     better balance,” says Yamaguchi.
    curred within a year of each other. The first   Ajinomoto’s future plans. While in the last       As part of its corporate mission, Ajino-
    ingredient the company manufactured,            century dietitians emphasized vitamins        moto Group is working to help solve some
    Aji-no-moto, umami seasoning based on           and minerals, the next century will be the    of the enormous challenges facing our
    glutamate, reflects its contribution to the     century of amino acids, according to Norio    planet—adequate food resources, sustain-
    food ingredient marketplace. “Aji-no-moto”      Yamaguchi, Chairman of the Board for the      ability, proper food and nutrition educa-
    is written in three characters in Japanese      Ajinomoto Group.                              tion, environmental pollution protection
    that literally mean the “essence of taste.”         The company has a new slogan to help      and the fight against global warming.
    The Ajinomoto Group not only has helped         carry it and its customers forward into its       While no effort is less important than
    bring heightened flavor to the world, but so    next century of business: ‘Eat Well—Live      another, the focus on food ingredients
    much more through its efforts in various        Well,’ which expresses the link between       includes a company growth strategy that is
    industries, based on the amazing proper-        our eating habits and their related effects   in accordance with ecological principles.
    ties derived from
    amino acids.

                                                                          Eat Well—Live Well
                                                              on health. “Instead of having to        As the global leader in amino acid
                                                           visit the doctor for a cure, amino     production and supply to the food chain,
                                                        acids can help bring us to the place      the Ajinomoto Group offers irreplaceable
                                                    where the entire focus of medicine shifts     value, especially in a world facing huge
                                                    from cure to prevention, a true focus on      issues of whether adequate food resources
                                                    wellness through foods,” says Jack Heaton,    can be secured for all humanity.
8
                                                    President, Ajinomoto Aminoscience.                Ajinomoto works globally but thinks
                                                         “When consumers eat well, or eat the     locally, bringing out the best in regional
                                                     right combination of foods for nourish-      cuisines and helping food industry profes-
                                                                                                  sionals create products that reach their
                                                                                                  fullest potential.



                    1983                            1986
                   amino-acid based                 heartland Lysine Inc., eddyville plant
                   sweetener aspartame              commences operations
                   introduced to revolution-
                   ize carbonated
    soft drinks, other beverages and sugar-
                                                    1993
                                                    ajinomoto U.s.a., Inc. Iowa msg plant
    free foods.
                                                    commences operations

    1984                                            1997
    heartland Lysine, Inc. established in
                                                    ajinomoto Biolatina opens
    the United states (presently ajinomoto
                                                    valparaiso plant
    heartland LLc)
                                                                                                  home-use product line-up (ca. 1990)
GRAS Plus
MSG - the natural flavor enhancer
how can a food IngredIent have                                   MYTH BuSTINg
a safety factor greater than GRAS, the “generally                sound scientific evidence refutes the idea that monosodium
recognized as safe” designation from the Food and                glutamate (msg) can cause adverse physical reactions in
Drug Administration? When that agency reviews the                people who eat it.
ingredient’s designation and calls for additional testing            from a letter in the new england Journal of medicine
by authorized, respected, scientifically sound principles        containing one person’s musings about his experience in a
and discovers it is indeed a benign ingredient.                  chinese restaurant, society threw science out the window and
     In 1992, the FDA contracted with the Federa-                and culturally fueled suspicion grew, with no basis in fact.
tion of American Societies for Experimental Biology                  the myth was thoroughly debunked in a 1999 vogue article
(FASEB), an independent group of scientists, to                  by Jeffrey steingarten entitled, “why doesn’t everybody in
complete the most comprehensive review of available              china have a headache?”
scientific data on glutamate safety to date.                         glutamate, a naturally occurring amino acid in our bodies,
     The 1995 FASEB report reaffirmed the safety of              is present in the first food we consume as babies. human breast
MSG when it is consumed at usual levels by the general           milk contains large amounts of glutamate at a level ten times
population and found no evidence of any connection               higher than glutamate present in cow’s milk. scientists believe
between MSG and any serious, long-term reactions.                the glutamate acts as a taste enhancer to encourage babies to
     In 1991 the European Community’s Scientific                 drink the milk so they can grow.
Committee for Food confirmed MSG safety. Food                        a sprinkle of Parmesan cheese on top of a favorite Italian
Standards Australia conducted a review even more                 dish contains 1200 mg of glutamate per 100g serving, giving
recently in 2002 and concluded that MSG is indeed a              the food a rich taste experience common to other foods high
safe ingredient. The Joint Expert Committee on Food              in natural glutamate levels. the chart below displays common
Additives of the United Nations Food and Agricul-                foods naturally rich in glutamate:
ture Organization and World Health Organization                      Food                            glutamate (mg/100g)
consider MSG one of the safest food additives. And                   Parmesan cheese                   8,210
the European Journal of Clinical Nutrition reiterated                cheddar cheese                    6,090
recently that MSG can be ”regarded as harmless for the               walnuts                           658
whole population.”                                                   fresh tomato                      310
     If Chinese restaurant syndrome were real, we                    Beans                             880
would hear comments about “steakhouse syndrome”                      steak                           > 2,000
or “Italian seafood restaurant syndrome” as glutamate                white mushrooms                   400
is a natural part of these delicious dishes. MSG is made             salmon                            3,840
up by the natural fermentation of glucose.                           Broccoli                          950



2000                                            2005
tecUs (technology & engineering                 ajinomoto Interamericana Limeira
center) established                             plant starts production of amino acids
                                                for foods and pharmaceuticals

                                                2006
                                                ajinomoto Biolatina opens Pederneiras     2009
                                                plant (production of                      ajinomoto company Inc. celebrates
                                                feed-use amino acids)                     100 years of leadership decoding and
                                                                                          using amino acids in food ingredients,
                                                                                          pharmaceuticals and other key
2000                                                                                      industries.
ajinomoto frozen foods U.s.a., Inc.,
established
Tokyo Based, Global Focus

                           A
                                jinomoto Food Ingredients, LLC
                                   Ajinomoto works continually to make it easier for its North American clients to
                                     incorporate amino acid power into food and beverage formulations. Ajinomoto
                                      Food Ingredients, LLC, recently opened its new application center in Chicago,
                                        Illinois, dedicated to supporting formulation development for dry or liquid
                                          beverage applications, seasoning blends and protein modification applications.
                                           Ajinomoto also operates a facility in Ames, Iowa dedicated to meat applica-
                           tions and designed to help support the Activa® transglutamanase business.
                                Ajinomoto’s enzyme capabilities help meat processors make a better profit with beef
                           tenderloin. Typically the tails or narrow ends of the tenderloins are too small to cut filets. By
                           binding two tenderloins, head or thick end to tail or the narrow end, processors will obtain
                           full size filet cuts. “Consumers cannot tell the difference between the filet using Activa and
                           the ones that don’t use the enzyme,” says Brendan Naulty, president of Ajinomoto Food In-
                           gredients, LLC. “The enzyme binds the meat together seamlessly and has no effect on flavor.”
                                Formerly, due to quick enzyme reaction, that technology was only available for small
                           batch operations. However, by creating a system that has a buffered pH, the enzyme activ-
                           ity is slowed down, enabling its use in large-scale operations.
                                Enzyme technology is not exclusive to proteins. In a foodservice or deli application,
                           for example, when pasta is kept in a warming tray, Activa can help the pasta maintain
                           its al dente texture for hours. In the dairy industry, Activa enzyme technology can trim
                           costs while improving quality in cheese, cream cheese and yogurt products. The enzyme
                           addition allows for greater water-binding by cross-linking amino acids within the dairy
                           protein. This helps maintain texture in string cheese or lends a clean ‘bite’ to pizza cheese.
                                “Our team members and facilities in the U.S. stand ready to help food manufacturers
                           operate with the utmost efficiency while improving product quality and presentation,” said
                           Naulty. “We’re here to serve our customers in North America by applying a combination
                           of a century’s worth of tradition, reputation for quality, and exciting new developments in
10
                           amino acid technology to applications for today’s marketplace.”

                           Ajinomoto AminoScience, LLC
                           Ajinomoto AminoScience, LLC, in Raleigh, N.C., operates within four major market
                           segments. Overall, its purified amino acids help improve life, with a business model that
                           focuses on purity, consistency and quality.
                                Out of the twenty amino acids the company manufactures, nine are produced in the
                           Raleigh facility. It is the only U.S.-based manufacturer of pharmaceutical grade amino
                           acids (cGMP), supplying much of the world’s supply of amino acids for pharmaceuti-
                           cal purposes. Primarily used for nutritional therapy, they supply nourishment that goes
                           directly into the bloodstream or serve as raw materials for producing therapeutic proteins,
     the B u S I N E S S




                           antibodies or vaccines via cell culture. Fifty years ago Ajinomoto was a pioneer in supply-
                           ing pharmaceutical grade amino acids to these key markets.
                                Other important markets include the nutritional industry, or amino acids for improv-
                           ing wellness, and the food industry, for infant formula, functional foods or functional food
                           additives. A recent company focus is the beverage segment, according to Jack Heaton,
                           company president.
                                Ajinomoto AminoScience has petitioned for GRAS (generally recognized as safe) cer-
                           tification for five of its amino acids. This will allow for broader use of its amino acids for food
FRIED NOODlES
                                                                                                      THAI STYlE
                                                                                                      Serves 2
                                                                                                      2 cups narrow rice noodles
                                                                                                      3 cups water
                                                                                                      1 cup diced firm tofu
                                                                                                      1 cup prawns, shelled and deveined
                                                                                                      2 tbsp chopped shallot
categories promoting their functional ben-         Amino acids can replace soybean meal               2 tbsp chopped garlic
efits. The beverage industry particularly is in    in swine and poultry diets to provide the          1 cup bean sprouts
constant competition to introduce enticing         animals with a more economical and better          2 eggs
new flavors and certain amino acids have a         balanced diet. Produced in the form of a           2 seeded chilies, soaked and
basis of flavor either alone or in combination.    dry powder, three pounds of lysine added               squeezed dry
Amino acids stimulate certain taste recep-         to 97 pounds of corn equals 100 pounds             2 tbsp dried shrimp
tors, sparking interest in their utilization for   of soybean meal, supplying the vital amino         2 tbsp chopped pickled white radish
flavoring. To accommodate this growing             acids the livestock requires in its diet, yet at   3 tbsp tamarind juice
interest in use as flavors the company has         a cost savings to the producer. Additional         1 tbsp sugar or palm sugar
updated its FEMA GRAS status.                      soybean meal can be replaced by supple-            1 tsp soy sauce
     The real excitement lies in the future        menting more (> 3 lbs) lysine with the             ½ tsp aji-no-moto (monosodium
of amino acids for better health. A variety        second limiting amino acid (threonine).                glutamate)
of studies are underway on the benefits of              As an additional benefit, the addition        3 tbsp chopped roasted peanuts
various amino acids for an expanding range         of the amino acid lysine to the animal diet        ¼ cup vegetable oil
of health benefits. Many scientists believe        helps lower nitrogen excretion, of concern         1/3 cup chinese leek, cut into
amino acids are the key to revolutionizing         to both agriculturalists and environmen-               one-inch lengths
our health care system, shifting the focus         talists. For every 1% drop in crude protein        1 lime, cut into 4 pieces
from curing illness to preventative care           (lowering soybean meal), nitrogen excre-
with a dedicated emphasis on wellness.             tion is reduced by approximately 10%. By           Boil the water, pour it over the rice
     “Most people today think of vitamins as       utilizing lysine and threonine in animal           noodles and leave until the noodles
a staple item that helps replenish the body’s      diets, nitrogen excretion can be lowered by        soak up the water.
supply of deficient elements in nutrition,”        20-30%. Amino acids increase the utiliza-              Pound the chilies, garlic and shal-
says Heaton. “Amino acids are more basic           tion efficiency of the nitrogen in feeds           lot until thoroughly ground.
yet than vitamins. Our DNA tells the body          (same animal performance with less con-                heat the oil in the wok. fry the
which proteins to synthesize to perform            sumed nitrogen). Adding amino acids to             chilies, garlic, pickled white radish
necessary bodily functions. Now we’re              the animal diet is highly beneficial for the       and shallot until fragrant, then the
studying the metabolome, the metabolism            animal, the farmer and the environment.            tofu, dried shrimp and prawn. season
and the proteins that define the way our                The animal feed grade lysine or amino         with the tamarind juice, sugar, soy
metabolism works, since everyone’s body            acid is produced in a U.S. based plant             sauce and umami seasoning. add
functions in a different way. The addition         in Eddyville, Iowa. Another amino acid             the noodles to the wok and stir fry
of amino acids into the body has a very real       produced there includes threonine.                 well. to finish, add the bean sprouts,
purpose. It can, in fact, aid in wellness—         Tryptophan and valine are marketed to the          chinese leek and egg. serve with the
in the same way that people take vitamin           animal industry by Ajinomoto Heartland             peanuts and lime.
C to prevent colds, for example, arginine          but produced in France. Feed-use amino
helps keep blood vessels more flexible and         acids also help reduce the amount of land
branched-chain amino acids help build              needed for grain production, achieving
skeletal muscle proteins.”                         the most economical and efficient use of
     Ajinomoto AminoScience LLC can meet           limited arable land.
any amino acid need, from initial research to           For animal feed processors, the lysine
manufacturing, blending and pulverization          and threonine substitution is an easy for-
through storage, labeling and packaging to         mulation adjustment to ensure the animal
analytical and technical support.                  receives an amino acid balanced diet.
                                                   Primary markets include the U.S., Canada,
Ajinomoto Heartland Lysine, LLC                    Mexico and the Caribbean. Another plant
Ajinomoto Heartland Lysine, Chicago, IL,           in Brazil supplies amino acids to the animal
supplies amino acids for animal nutrition.         nutrition markets in South America.
Ajinomoto group Philosophy:

               Our philosophy is to contribute significant
             advances in Food and Health on a global basis
               and ultimately to create a better life for all.




Ajinomoto Food             Ajinomoto AminoScience llC   Ajinomoto Heartland llC   Ajinomoto Co. Inc.        Ajinomoto Interamericana
Ingredients llC            4020 ajinomoto drive         8430 w. Bryn mawr ave.    european headquarters     Indústria e Comércio ltda.
8430 west Bryn mawr ave.   raleigh, nc 27610, Usa       suite 650                 153 rue de courcelles     rue Joaquim tavora 541
suite 635                  tel: 919-325-1400            chicago, IL 60631, Usa    75817 Paris cedex 17      villa mariana
chicago, IL 60631, Usa     fax: 919-325-1420            tel: + 1 773 380 7000     france                    sao Paulo, sP – 04015-901
tel: 773-714-1436                                       fax: + 1 773 380 7006     tel: 33-(1) 47-66-98-63   Brazil
fax: 773-714-1431                                                                 fax: 33-(1) 47-66-98-56   tel: 55-(11) 5080 6742
                                                                                                            fax: 55-(11) 5080 6739
                                                                                  tokyo headquarters
                                                                                  tel: +81-3-5250-8111

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Ajino moto

  • 1. Celebrating a 100 Year Legac Y of InnovatIon
  • 2. Although only recently accepted into the international food lexicon, umami, the fifth taste stretches back into the annals of food history. Many popular foods and seasonings evoke In the the umami taste, although it remained unidentified in a scientific sense. By Jeanne turner A fermented or pickled fish sauce called garum, rich in umami taste and char- acteristics, is one of the earliest recorded flavoring agents used in ancient Greece and Rome when Aristotle identified seven basic tastes: sweet, salty, sour, bitter, spicy, astringent and sandy. Chinese records from as early as 1,000 B.C. documented five tastes. Other ancient cultures also record more than four basic tastes. Dashi ingredients from left to right: Kombu (kelp); Katsuobushi (Dried bonito); Niboshi (Small dried fish); Dried Shiitake mushroom; Water 2 Apparently the ideas of a different Greek philosopher, Democritus, held greater power than Aristotle’s, as his identification of four basic tastes—sweet, salty, sour and bitter— became the world’s standard for almost 2,500 years. As modern science progressed in the early nineteenth century, giving us a better understanding of the human body with micro- scopic views of the tongue and taste buds, all evidence appeared to confirm the existence of just four different taste receptors. In 1903 the renowned French chef, Auguste Escoffier, published a cookbook including his original creation, veal stock, suggesting a fifth taste was responsible for the delicious flavor of this culinary masterpiece. But his assertions went no further at that time. In fact, among culinary treasures to emerge in the last century, perhaps none has had a great- er impact on the global community than umami—so complex it almost defies description, yet the H I S T O R Y so universal it is a wonder its secrets remained hidden for so long. Throughout the world, every culture can identify indigenous sources of umami. Nordic lands have anchovies, cod roe paste and dried fish. In South America and the Caribbean, dried shrimp improve the taste of soups, stews and rice dishes. Tomatoes, another source of umami, are native to Peru and Ecuador. What was the key that unlocked umami’s secret once and for all? It came in 1908 from yet another culture familiar with savory sensations that formed the backdrop to traditional dishes, as a Tokyo University professor decided to investigate the scientific explanation for the intriguing taste of dashi.
  • 3. The Root of Umami Discovery resIdents of an IsLand distinctive that a good dashi helps reduce seaweed that helps lend dashi its distinc- nation, the Japanese people resourcefully the need for salt and oil and helps create tive umami profile, has the highest natural use the bounty the sea provides to enhance healthier nutritional profiles. levels of glutamate in the world. and enrich their cuisine. Not only do cer- Seasonality also plays an important Umami can be described as the savory tain foods and ingredients play a role in the role in Japanese culture and cuisine. The taste imparted by glutamate and five daily diet, they also have such an ancient garnishes selected, the food presentation, ribonucleotides, including inosinate and heritage that they are interwoven into the even the dishes chosen to serve the food guanylate, identified in 1913 and 1957 history of Japanese culture. The best ex- are selected for their seasonal suitability, respectively, which occur naturally in ample of this is dashi, a carefully prepared and food or ingredients used in their proper many foods, including meat, fish, certain stock that forms the basis for multiple season are said to be in “shun.” This focus vegetables and dairy products. Another nucleotide, adenylate, identified in the 1960s, is abundant in fish and shellfish. While the Japanese have enjoyed the benefits of umami in their cuisine for cen- turies, the Western world only recently em- braced the concept of umami. Professional chefs in the West now experiment with the types of ingredients that give the distinctive umami signature to a prepared meal. 3 dishes within Japanese cuisine. on seasonality portrays the link between Further research in the 1980s solidi- Dashi is a deceptively simple stock cre- nature and food that is deeply ingrained fied umami’s acceptance as the fifth taste ated using carefully dried and prepared in- within Japanese cooking. Dashi might serve in the international lexicon. Umami gredients. Dashi relies upon the combina- as the basis for various popular dishes eaten acts synergistically with other flavors tion of kombu, or dried kelp seaweed, and in season, with winter dishes such as Pork to enhance and amplify their effect, to katsuobushi, or dried bonito flakes, mixed and Miso Soup (Tonjiru) or Simmered bring out the full boldness and richness with other ingredients as distinctive as the Daikon Radish; or summer dishes such of the entire formulation for a heightened chef who prepares his or her own unique as Grilled eggplant in dashi, or Somen, a gastronomic experience. variety. The kombu and katsuobushi are wheat noodle served with dipping sauce. In addition to its role as a palate pleaser, carefully selected, aged and dried. In 1908, Professor Kikunae Ikeda of umami is beneficial for human survival Whereas a Western bouillon might Tokyo Imperial University drilled down in the most primal sense. Each of the five simmer any number of fresh ingredients to the bare essence of dashi’s ingredients tastes recognized by the human body has for hours in a reduction, the dried dashi and identified a taste that could not be a special role to play. Historically, the tastes ingredients are soaked in water or heated explained by any of the four traditional either encourage us to pursue the proper only briefly to extract the bare essence of tastes—sweet, salty, sour, bitter—or any nourishment for survival or warn us away flavor. Steeping the ingredients in hot water combination of the four. Dr. Ikeda’s investi- from harmful foods. For example, we allows the amino acids to infuse the broth, gations led him to L-glutamate, the source desire sweet foods to help maintain enough as amino acids are the basis of the stock’s of this taste, and he named the taste itself calories in our body and salty foods to help unique taste. This taste is so rich and “umami.” In fact, kombu, the dried kelp us maintain a proper mineral 
  • 4. Thai Salad balance. Many sour or bitter foods were poisonous or dangerous to humans, so those two tastes acted as a warning. 4 Our preference for and delight in foods with umami taste helps us ensure we consume the proper amount of amino acids for our bodily needs, which include, among many other functions, the Atsukezuri, Katsuobushi shavings right amount and type of proteins to help rebuild muscle tissue after exertion or exercise. But if you talk to chefs or other experts, they say a key characteristic of umami is to make your mouth water. Closely associated with foods in season that are ripened or matured, umami is a taste that reaches its best potential Miso through foods served at the peak of matu- rity to help promote good health. As foods ripen or mature, the amino acid content Dashi increases, enhancing the umami effect.
  • 5. When Science Meets Culinary Arts G lutamate, otherwise known as L-glutamate or monosodium glutamate (MSG), identified as the key amino acid responsible for umami flavor, is not exclusive to kombu. It is also common in Western ingredients with savory flavor, such as Parmesan cheese, asparagus, tomatoes, meat and anchovies (which NPR science writer Jonah Lehrer termed “glutamate speedballs”). Upon further investigation, research confirmed that these foods could also be included under the description of umami with respect to their amino acid profile. This could be one reason why, once Western chefs grasped the implications of umami, it took the culinary world by storm—it was always present yet unidentified; once acknowledged, it allowed for discovery of savory food cat- egories containing the essence of umami that could enhance fine cuisine. Just as with the other four basic tastes, the tongue has taste receptors that are tuned into umami. Scientific studies in recent years have also shown that the stomach contains glutamate receptors, and that the amino acid glutamate plays an important role in food digestion. Molecular gastronomy examines the link between the physical and chemical processes that occur during cooking and is becoming a focus of attention among chefs, researchers and food writers world- wide. It connects the scientific explanation for food or ingredient behavior with the 5 social, artistic and technical components of culinary processes. Some examples of the types of issues examined via molecular gastronomy might include the study of how various ingredients change depen- dent upon different cooking methods, and investigation into the question: Can we devise new cooking methods that produce unusual and improved results of texture and flavor? As science continues to join forces with the S C I E N C E the culinary arts, Ajinomoto Company Inc. is committed to assisting with the development of healthier foods enhanced with umami-based ingredients, to not only help create better tasting food but to help develop a healthier population as well.
  • 6. The 21st Century – “The Century of Amino Acids” amIno acIds, whIch most in and essential to the human body. Water mapped out our DNA genetic make up scientists acknowledge as the building accounts for approximately 60% of our body while the next project is determining the blocks of life, are critical to life and function weight, followed by amino acids (proteins), proteome, or the make up of all the proteins in a wide variety of ways in multiple indus- constituting 20%. Amino acids perform vari- that exist in the human body. Scientists tries and within the human body, including ous important functions and make up vital suspected there were between 10,000 or activity related to flavoring, nutritional func- body tissues such as muscles, the gastroin- 20,000 proteins; now they admit they don’t tion, physiological well being, and reactivity. testinal tract, internal organs, hemoglobin even know the final number.” Amino acid-based ingredients provide a contained in red blood cells, and collagen, Amino acids play a role in areas as di- wide range of tastes or benefits to foods, such the main component of our hair and skin. verse as seasonings, pharmaceuticals, nutri- as umami or sweet taste sensations supplied Athletes were among the first to discover tional supplements, cosmetics, fertilizers and by monosodium glutamate and aspartame and use amino acid-based foods and ingre- livestock feed. Some scientists and humani- dients to help rebuild muscle during or after tarians believe amino acids hold the key to a workout. Science confirmed that helping solve the global issue of malnutrition the human body during exercise and due to inadequate protein intake. Amino recovery utilizes most rapidly pro- acid fortification is a cost-effective, highly teins that have a certain amino acid bioavailable method of maximizing limited composition, specifically branched- food supplies. Ajinomoto Group also utilizes chain amino acids (BCAAs such the nutrient-rich byproduct generated dur- as valine, leucine, and isoleucine), ing amino acid production to convert food which promote the protein synthesis supplies into valuable coproducts such as of skeletal muscles. fertilizer or feed, which reduces the waste Despite scientific advances, stream and helps preserve our ecosystem. lately the research community has Overall, research proves that essential discovered it has barely scratched amino acids are necessary for proper bodily the surface of the vast universe of function and nutritional balance. The Aji- respectively. In this capacity, amino amino acids and proteins that exist nomoto Group believes that amino acids acid-based ingredients help enhance within the human body, or their hold the key to future development of food, 6 or highlight the natural flavors of other functions. “We have between 100,000 nutritional products and pharmaceuticals. ingredients, foods and seasonings while or more different proteins that make our Ajinomoto will continue to be the world’s remaining in the background. bodies function properly,” said Jack Heaton, premier company committed to providing Far from being obscure synthetic sub- president of Ajinomoto Scientific Group, better health, nutrition and quality of life stances, amino acids are naturally present LLC, Raleigh, N.C. “The genome project through amino acid creation and utilization. 1908 1956 1963 dr. Kikunae Ikeda ajinomoto U.s.a., Inc., ajinomoto concludes tie-up obtains patent formally established with cPc International Inc. to produce (presently Unilever Bestfoods) L-glutamate 1956 as the source of ‘umami.’ ajinomoto do Brazil Industria 1968 e comercio, s.a established ajinomoto del Peru s.a. established 1909 aji-no-moto, the product, 1962 1973 is launched as umami ajinomoto concludes tie-up ajinomoto concludes tie-up with seasoning based on with Kellogg company general foods corporation; glutamate. reincorporated in Japan as ajinomoto general foods, Inc.
  • 7. Sweeeeettttt!!!! sImILar to BUILdIng BLocKs, populations such as diabetics a great deal human body metabolizes all essential ami- which in multiple permutations can create of variety and flexibility in budgeting total no acids in the same way. When a person myriad structures, amino acids in various carbohydrate intake without affecting consumes aspartame, the body breaks it molecular combinations can create an blood sugar. And with an increased focus down into aspartic acid, phenylalanine and astonishing variety of food ingredients. The on obesity within the general population, a small amount of methanol, identical to same substance that creates the unique aspartame can help tame weight manage- that found naturally in pectin-containing savory taste of umami is also responsible, in ment issues by enabling product develop- food products. The rest of the diet provides a different form, for mimicking the unique ers to create foods with a sweet profile much greater quantities of taste of sugar. yet reduced calorie count compared to a these components than Aspartame is approximately 200 times sugar-sweetened counterpart. does aspartame. sweeter than sugar, which means that 200 From frozen novelties to hard candies kg of sugar can be replaced with 1 kg of as- to iced tea, cocoa mixes and carbonated partame. Aspartame has an energy value of soft drinks, aspartame enhances the 4 calories per gram but, because only min- eating experience of consumers world- ute amounts of aspartame are required to wide without adding to provide the equivalent sweetness of sugar, the waistline. it can reduce a product’s calorie content by up to 99%. It offers excellent solubility and is suitable for most product applications within a certain pH and temperature range. Aspartame is utilized as a stable sweetener Aspartame is a dipeptide in products ranging from homogenized composed of two amino acids: dairy foods to beverages, frozen desserts, L-aspartic acid and L-phenylalanine. confections, baked goods, cereals and fruit Phenylanine is an essential amino preserves. In addition, aspartame can in- acid, considered essential for tensify and extend fruit flavors in foods and proper bodily function and beverages. For example, aspartame makes good health. Many com- 7 chewing gum taste sweet up to four times mon foods, such as longer than gum sweetened with sugar. meat, cheese, fish, Aspartame does not promote tooth vegetables or fruit, decay and is an FDA-approved, safe also contain these sweetening agent, and thus offers special constituents, and the 1974 1980 1982 eUroLYsIne s.a. established ajinomoto danone co., Ltd. ajinomoto opens pharmaceutical- in france established (presently calpis grade L-amino acid manufacturing ajinomoto danone co., Ltd.) plant in raleigh, n.c. 1974 ajinomoto Interamericana Industria e 1981 1983 comercio Ltda. established in Brazil aspartame available nutrasweet ag established in for tabletop use switzerland (presently ajinomoto 1975 sweeteners europe) nissin-ajinomoto alimentos Ltda. established
  • 8. A Look Ahead the scIentIfIc dIscoverY Just as amino acids are the building ment, they also will live well, or live better, of glutamate as the basis for umami taste blocks for so many unique and diverse and it is our goal to help them achieve this and the foundation of Ajinomoto oc- products, they also form the platform for better balance,” says Yamaguchi. curred within a year of each other. The first Ajinomoto’s future plans. While in the last As part of its corporate mission, Ajino- ingredient the company manufactured, century dietitians emphasized vitamins moto Group is working to help solve some Aji-no-moto, umami seasoning based on and minerals, the next century will be the of the enormous challenges facing our glutamate, reflects its contribution to the century of amino acids, according to Norio planet—adequate food resources, sustain- food ingredient marketplace. “Aji-no-moto” Yamaguchi, Chairman of the Board for the ability, proper food and nutrition educa- is written in three characters in Japanese Ajinomoto Group. tion, environmental pollution protection that literally mean the “essence of taste.” The company has a new slogan to help and the fight against global warming. The Ajinomoto Group not only has helped carry it and its customers forward into its While no effort is less important than bring heightened flavor to the world, but so next century of business: ‘Eat Well—Live another, the focus on food ingredients much more through its efforts in various Well,’ which expresses the link between includes a company growth strategy that is industries, based on the amazing proper- our eating habits and their related effects in accordance with ecological principles. ties derived from amino acids. Eat Well—Live Well on health. “Instead of having to As the global leader in amino acid visit the doctor for a cure, amino production and supply to the food chain, acids can help bring us to the place the Ajinomoto Group offers irreplaceable where the entire focus of medicine shifts value, especially in a world facing huge from cure to prevention, a true focus on issues of whether adequate food resources wellness through foods,” says Jack Heaton, can be secured for all humanity. 8 President, Ajinomoto Aminoscience. Ajinomoto works globally but thinks “When consumers eat well, or eat the locally, bringing out the best in regional right combination of foods for nourish- cuisines and helping food industry profes- sionals create products that reach their fullest potential. 1983 1986 amino-acid based heartland Lysine Inc., eddyville plant sweetener aspartame commences operations introduced to revolution- ize carbonated soft drinks, other beverages and sugar- 1993 ajinomoto U.s.a., Inc. Iowa msg plant free foods. commences operations 1984 1997 heartland Lysine, Inc. established in ajinomoto Biolatina opens the United states (presently ajinomoto valparaiso plant heartland LLc) home-use product line-up (ca. 1990)
  • 9. GRAS Plus MSG - the natural flavor enhancer how can a food IngredIent have MYTH BuSTINg a safety factor greater than GRAS, the “generally sound scientific evidence refutes the idea that monosodium recognized as safe” designation from the Food and glutamate (msg) can cause adverse physical reactions in Drug Administration? When that agency reviews the people who eat it. ingredient’s designation and calls for additional testing from a letter in the new england Journal of medicine by authorized, respected, scientifically sound principles containing one person’s musings about his experience in a and discovers it is indeed a benign ingredient. chinese restaurant, society threw science out the window and In 1992, the FDA contracted with the Federa- and culturally fueled suspicion grew, with no basis in fact. tion of American Societies for Experimental Biology the myth was thoroughly debunked in a 1999 vogue article (FASEB), an independent group of scientists, to by Jeffrey steingarten entitled, “why doesn’t everybody in complete the most comprehensive review of available china have a headache?” scientific data on glutamate safety to date. glutamate, a naturally occurring amino acid in our bodies, The 1995 FASEB report reaffirmed the safety of is present in the first food we consume as babies. human breast MSG when it is consumed at usual levels by the general milk contains large amounts of glutamate at a level ten times population and found no evidence of any connection higher than glutamate present in cow’s milk. scientists believe between MSG and any serious, long-term reactions. the glutamate acts as a taste enhancer to encourage babies to In 1991 the European Community’s Scientific drink the milk so they can grow. Committee for Food confirmed MSG safety. Food a sprinkle of Parmesan cheese on top of a favorite Italian Standards Australia conducted a review even more dish contains 1200 mg of glutamate per 100g serving, giving recently in 2002 and concluded that MSG is indeed a the food a rich taste experience common to other foods high safe ingredient. The Joint Expert Committee on Food in natural glutamate levels. the chart below displays common Additives of the United Nations Food and Agricul- foods naturally rich in glutamate: ture Organization and World Health Organization Food glutamate (mg/100g) consider MSG one of the safest food additives. And Parmesan cheese 8,210 the European Journal of Clinical Nutrition reiterated cheddar cheese 6,090 recently that MSG can be ”regarded as harmless for the walnuts 658 whole population.” fresh tomato 310 If Chinese restaurant syndrome were real, we Beans 880 would hear comments about “steakhouse syndrome” steak > 2,000 or “Italian seafood restaurant syndrome” as glutamate white mushrooms 400 is a natural part of these delicious dishes. MSG is made salmon 3,840 up by the natural fermentation of glucose. Broccoli 950 2000 2005 tecUs (technology & engineering ajinomoto Interamericana Limeira center) established plant starts production of amino acids for foods and pharmaceuticals 2006 ajinomoto Biolatina opens Pederneiras 2009 plant (production of ajinomoto company Inc. celebrates feed-use amino acids) 100 years of leadership decoding and using amino acids in food ingredients, pharmaceuticals and other key 2000 industries. ajinomoto frozen foods U.s.a., Inc., established
  • 10. Tokyo Based, Global Focus A jinomoto Food Ingredients, LLC Ajinomoto works continually to make it easier for its North American clients to incorporate amino acid power into food and beverage formulations. Ajinomoto Food Ingredients, LLC, recently opened its new application center in Chicago, Illinois, dedicated to supporting formulation development for dry or liquid beverage applications, seasoning blends and protein modification applications. Ajinomoto also operates a facility in Ames, Iowa dedicated to meat applica- tions and designed to help support the Activa® transglutamanase business. Ajinomoto’s enzyme capabilities help meat processors make a better profit with beef tenderloin. Typically the tails or narrow ends of the tenderloins are too small to cut filets. By binding two tenderloins, head or thick end to tail or the narrow end, processors will obtain full size filet cuts. “Consumers cannot tell the difference between the filet using Activa and the ones that don’t use the enzyme,” says Brendan Naulty, president of Ajinomoto Food In- gredients, LLC. “The enzyme binds the meat together seamlessly and has no effect on flavor.” Formerly, due to quick enzyme reaction, that technology was only available for small batch operations. However, by creating a system that has a buffered pH, the enzyme activ- ity is slowed down, enabling its use in large-scale operations. Enzyme technology is not exclusive to proteins. In a foodservice or deli application, for example, when pasta is kept in a warming tray, Activa can help the pasta maintain its al dente texture for hours. In the dairy industry, Activa enzyme technology can trim costs while improving quality in cheese, cream cheese and yogurt products. The enzyme addition allows for greater water-binding by cross-linking amino acids within the dairy protein. This helps maintain texture in string cheese or lends a clean ‘bite’ to pizza cheese. “Our team members and facilities in the U.S. stand ready to help food manufacturers operate with the utmost efficiency while improving product quality and presentation,” said Naulty. “We’re here to serve our customers in North America by applying a combination of a century’s worth of tradition, reputation for quality, and exciting new developments in 10 amino acid technology to applications for today’s marketplace.” Ajinomoto AminoScience, LLC Ajinomoto AminoScience, LLC, in Raleigh, N.C., operates within four major market segments. Overall, its purified amino acids help improve life, with a business model that focuses on purity, consistency and quality. Out of the twenty amino acids the company manufactures, nine are produced in the Raleigh facility. It is the only U.S.-based manufacturer of pharmaceutical grade amino acids (cGMP), supplying much of the world’s supply of amino acids for pharmaceuti- cal purposes. Primarily used for nutritional therapy, they supply nourishment that goes directly into the bloodstream or serve as raw materials for producing therapeutic proteins, the B u S I N E S S antibodies or vaccines via cell culture. Fifty years ago Ajinomoto was a pioneer in supply- ing pharmaceutical grade amino acids to these key markets. Other important markets include the nutritional industry, or amino acids for improv- ing wellness, and the food industry, for infant formula, functional foods or functional food additives. A recent company focus is the beverage segment, according to Jack Heaton, company president. Ajinomoto AminoScience has petitioned for GRAS (generally recognized as safe) cer- tification for five of its amino acids. This will allow for broader use of its amino acids for food
  • 11. FRIED NOODlES THAI STYlE Serves 2 2 cups narrow rice noodles 3 cups water 1 cup diced firm tofu 1 cup prawns, shelled and deveined 2 tbsp chopped shallot categories promoting their functional ben- Amino acids can replace soybean meal 2 tbsp chopped garlic efits. The beverage industry particularly is in in swine and poultry diets to provide the 1 cup bean sprouts constant competition to introduce enticing animals with a more economical and better 2 eggs new flavors and certain amino acids have a balanced diet. Produced in the form of a 2 seeded chilies, soaked and basis of flavor either alone or in combination. dry powder, three pounds of lysine added squeezed dry Amino acids stimulate certain taste recep- to 97 pounds of corn equals 100 pounds 2 tbsp dried shrimp tors, sparking interest in their utilization for of soybean meal, supplying the vital amino 2 tbsp chopped pickled white radish flavoring. To accommodate this growing acids the livestock requires in its diet, yet at 3 tbsp tamarind juice interest in use as flavors the company has a cost savings to the producer. Additional 1 tbsp sugar or palm sugar updated its FEMA GRAS status. soybean meal can be replaced by supple- 1 tsp soy sauce The real excitement lies in the future menting more (> 3 lbs) lysine with the ½ tsp aji-no-moto (monosodium of amino acids for better health. A variety second limiting amino acid (threonine). glutamate) of studies are underway on the benefits of As an additional benefit, the addition 3 tbsp chopped roasted peanuts various amino acids for an expanding range of the amino acid lysine to the animal diet ¼ cup vegetable oil of health benefits. Many scientists believe helps lower nitrogen excretion, of concern 1/3 cup chinese leek, cut into amino acids are the key to revolutionizing to both agriculturalists and environmen- one-inch lengths our health care system, shifting the focus talists. For every 1% drop in crude protein 1 lime, cut into 4 pieces from curing illness to preventative care (lowering soybean meal), nitrogen excre- with a dedicated emphasis on wellness. tion is reduced by approximately 10%. By Boil the water, pour it over the rice “Most people today think of vitamins as utilizing lysine and threonine in animal noodles and leave until the noodles a staple item that helps replenish the body’s diets, nitrogen excretion can be lowered by soak up the water. supply of deficient elements in nutrition,” 20-30%. Amino acids increase the utiliza- Pound the chilies, garlic and shal- says Heaton. “Amino acids are more basic tion efficiency of the nitrogen in feeds lot until thoroughly ground. yet than vitamins. Our DNA tells the body (same animal performance with less con- heat the oil in the wok. fry the which proteins to synthesize to perform sumed nitrogen). Adding amino acids to chilies, garlic, pickled white radish necessary bodily functions. Now we’re the animal diet is highly beneficial for the and shallot until fragrant, then the studying the metabolome, the metabolism animal, the farmer and the environment. tofu, dried shrimp and prawn. season and the proteins that define the way our The animal feed grade lysine or amino with the tamarind juice, sugar, soy metabolism works, since everyone’s body acid is produced in a U.S. based plant sauce and umami seasoning. add functions in a different way. The addition in Eddyville, Iowa. Another amino acid the noodles to the wok and stir fry of amino acids into the body has a very real produced there includes threonine. well. to finish, add the bean sprouts, purpose. It can, in fact, aid in wellness— Tryptophan and valine are marketed to the chinese leek and egg. serve with the in the same way that people take vitamin animal industry by Ajinomoto Heartland peanuts and lime. C to prevent colds, for example, arginine but produced in France. Feed-use amino helps keep blood vessels more flexible and acids also help reduce the amount of land branched-chain amino acids help build needed for grain production, achieving skeletal muscle proteins.” the most economical and efficient use of Ajinomoto AminoScience LLC can meet limited arable land. any amino acid need, from initial research to For animal feed processors, the lysine manufacturing, blending and pulverization and threonine substitution is an easy for- through storage, labeling and packaging to mulation adjustment to ensure the animal analytical and technical support. receives an amino acid balanced diet. Primary markets include the U.S., Canada, Ajinomoto Heartland Lysine, LLC Mexico and the Caribbean. Another plant Ajinomoto Heartland Lysine, Chicago, IL, in Brazil supplies amino acids to the animal supplies amino acids for animal nutrition. nutrition markets in South America.
  • 12. Ajinomoto group Philosophy: Our philosophy is to contribute significant advances in Food and Health on a global basis and ultimately to create a better life for all. Ajinomoto Food Ajinomoto AminoScience llC Ajinomoto Heartland llC Ajinomoto Co. Inc. Ajinomoto Interamericana Ingredients llC 4020 ajinomoto drive 8430 w. Bryn mawr ave. european headquarters Indústria e Comércio ltda. 8430 west Bryn mawr ave. raleigh, nc 27610, Usa suite 650 153 rue de courcelles rue Joaquim tavora 541 suite 635 tel: 919-325-1400 chicago, IL 60631, Usa 75817 Paris cedex 17 villa mariana chicago, IL 60631, Usa fax: 919-325-1420 tel: + 1 773 380 7000 france sao Paulo, sP – 04015-901 tel: 773-714-1436 fax: + 1 773 380 7006 tel: 33-(1) 47-66-98-63 Brazil fax: 773-714-1431 fax: 33-(1) 47-66-98-56 tel: 55-(11) 5080 6742 fax: 55-(11) 5080 6739 tokyo headquarters tel: +81-3-5250-8111