This document outlines the regional engagement strategy of CCAFS, which focuses on empowering stakeholders in three regions: Indo-Gangetic Plains, West Africa, and East Africa. The strategy involves integrating thematic research, participatory priority setting, effective regional partnerships, and capacity building. Key actions include designing climate-smart agriculture in benchmark sites and assessing vulnerabilities at sub-national and national scales. The strategy aims to build capacity of farmers, NGOs, and policymakers through participatory action research and farmer exchanges to achieve outcomes like enhanced adaptation plans and improved early warning systems.