1. Catalina Bermúdez González
Third semester
Molecular biology
Bolivarian Pontifical University

4. • DNA be template for the synthesis of
Transcriptio RNA by the enzyme RNA polymerase
n
• RNA serves as an intermediary to
carry the genetic information from the
nucleus to the cytoplasm
Translation • Serves as template for the synthesis
of proteins
DNA
RNA
Double chain
Single chain
Desoxirribose
Ribose sugar
sugar
Uracil
Timine

5.  Science Daily (Jan. 9, 2012)

6.  The Scientifics are searching
alternatives genetic molecules
for know how the first life began
 TNA is a nucleic acid similar to
DNA and RNA but has a threose
(tetrose sugar) so is more
simple than de ribose or
desoxiribose sugar, so could
assemble more easily in a
probiotic world

7.  A single strand of TNA can
bind with DNA and RNA
using polymerase enzymes
 TNA nucleotides could
attach by complementary
base pairing to a random
sequence of DNA, forming a
hybrid DNA-TNA strand

8.  TNA can fold into complex shapes that can
bind to a desired target with high affinity so
the scientifics hope to produce a TNA as a
high-specificity binding receptor for the
human protein thrombin

9. Beside for be a new
knowledge with a great
application in medicine and
high technologist especially
in gene therapy, if
it continues to deepen the
study could be a new theory
about the origin of life .

10.  By Sabrina Richards
(January 19, 2012)

11.  Use DNA’s
simplicity to build
nanostructures of
DNA that mimic
polymerases or
another enzymes
for do biological
process

12.  DNA nanostructures is
used to enzymatic
reactions
 Meta-DNA structures
was build using pieces
of DNA
 Meta-bases are three
strands of double-
stranded DNA. The ends
of strand complement
the other two

13.  Meta-DNA act like enzymes and providing an
opening for other single-stranded bit of
meta-DNA to bind. New meta-bases could
start binding allowing for possible enzymatic
reactions.
 The meta-DNA should eliminate unnecessary
unpredictability of RNA and proteins but to
become useful, have to interact proteins and
the preform reactions more slowly

14. This development would
facilitate gene therapy
and become more efficient
in terms of
reduction process should be
done, but I think it is a study
that is still not
very viable because
the target DNA require
the interaction with
proteins and
reactions develop more
slowly

16.  These developments increasingly
specialized can be used extensively in
medicine, especially in gene therapy.

17.  The TNA can be adopted to
mark places of micro
clots doing to
bring human protein Throm
bin receptor be useful for
surgery
 As the TNA a precursor
molecule of primitive life
forms could be
created vectors carrying
DNA strands or drugs
directly to cellular receptors

18.  With regard to self-
replication of DNA if a
string can start
processes that
normally require many
other factors, would be
more efficient therapy.
 The most important thing is
to give the patient
the greatest possible
comfort and quality of
life because after all the
objetive of science is
always to serve the people

19.  MARTINEZ SANCHEZ , Lina María. Biología
molecular. 6. ed. Medellín: UPB. Facultad de
medicina, 2012. 70 p.
 Simpler Times: Did an Earlier Genetic Molecule
Predate DNA and RNA?. Science daily [seriada en
línea]. Enero 9, 2012. Disponible en: URL:
http://www.sciencedaily.com/releases/2012/01/12
0109103029.htm. Consultado Enero, 2012.
 RICHARDS, Sabrina. Can DNA Self-replicate?.The
Scientist: Magazine of the life sciences [Seriada en
línea] Enero 19, 2012. Disponible en:
URL:http://the-scientist.com/2012/01/19/can-
dna-self-replicate/. Consultado Enero, 2012