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Understanding Capillary
Filtration Pressure
Casey Christy, MA, ATC, CSCS
Key Terms
• Capillary Hydrostatic Pressure
(CHP): pressure exerted by water
in the blood which forces fluid out
of the capillary
• Tissue Hydrostatic Pressure
(THP): pressure that forces fluid
back into the capillary
Key Terms
• Capillary Oncotic Pressure
(COP): pressure that pulls fluid
back into the capillary

• Tissue Oncotic Pressure (TOP):
pressure that pulls fluid out of the
capillary as a result of free proteins
attracting fluid
Note that “oncotic pressure” is also known as “colloid osmotic pressure”
Sum of Forces
• Capillary Filtration Pressure
(CFP) is expressed as an
equation:
• CFP= (CHP+TOP) – (THP+COP)
Capillary Filtration
PRessure
• Here it is again spelled out:
Capillary Filtration Pressure =

(Capillary Hydrostatic Pressure + Tissue Oncotic
Pressure)
minus
(Tissue Hydrostatic Pressure + Capillary Oncotic
Pressure)
Capillary Filtration
PRessure
• The sum of these forces that make up
CFP determines which way fluid
travels and is also known as “Starling
Forces”

• Normal (non-injured) CFP is slightly
positive
Starling Forces
Tissue Oncotic
Pressure

Capillary
Hydrostatic
Pressure

Tissue
Hydrostatic
Pressure

Capillary
Tissue

Capillary
Oncotic
Pressure
Capillary Filtration
PRessure
• Hydrostatic forces “push” fluids

• Oncotic forces “draw” fluids
Capillary Filtration
PRessure
• CHP is normally positive at the
arteriolar end of the capillary, causing
fluid to move out of the capillary and
into the tissue

• At the venular end of the
capillary, forces are different to allow
resorption of fluid back into the
capillary
When Injury Occurs
• When an injury occurs Capillary
Filtration Pressure (CHP) changes as
a result of increased Tissue Oncotic
Pressure (TOP), causing edema
accumulation in the tissue
• Read on to see why…
When Injury Occurs
• When an injury occurs, free proteins
escape into the tissue as a result of
increased capillary
permeability, tissue debris, or blood
vessel bleeding
• This increases Tissue Oncotic
Pressure (TOP) which draws fluid into
the tissue resulting in edema and
When Injury Occurs
• Normally (no injury), 2/3 of the fluid
leaving the capillary is reabsorbed into
the capillary, and the rest is picked up
by the lymphatic system

• With an injury, this system is
overloaded since more fluid is exiting
the capillary than can be absorbed
When Injury Occurs
• In summary, capillary filtration
pressure increases when an injury
occurs, leading to fluid buildup in the
tissues
Reference
• Knight and Draper, Therapeutic
Modalities: The Art and Science

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Capillary filtration pressure

  • 2. Key Terms • Capillary Hydrostatic Pressure (CHP): pressure exerted by water in the blood which forces fluid out of the capillary • Tissue Hydrostatic Pressure (THP): pressure that forces fluid back into the capillary
  • 3. Key Terms • Capillary Oncotic Pressure (COP): pressure that pulls fluid back into the capillary • Tissue Oncotic Pressure (TOP): pressure that pulls fluid out of the capillary as a result of free proteins attracting fluid Note that “oncotic pressure” is also known as “colloid osmotic pressure”
  • 4. Sum of Forces • Capillary Filtration Pressure (CFP) is expressed as an equation: • CFP= (CHP+TOP) – (THP+COP)
  • 5. Capillary Filtration PRessure • Here it is again spelled out: Capillary Filtration Pressure = (Capillary Hydrostatic Pressure + Tissue Oncotic Pressure) minus (Tissue Hydrostatic Pressure + Capillary Oncotic Pressure)
  • 6. Capillary Filtration PRessure • The sum of these forces that make up CFP determines which way fluid travels and is also known as “Starling Forces” • Normal (non-injured) CFP is slightly positive
  • 8. Capillary Filtration PRessure • Hydrostatic forces “push” fluids • Oncotic forces “draw” fluids
  • 9. Capillary Filtration PRessure • CHP is normally positive at the arteriolar end of the capillary, causing fluid to move out of the capillary and into the tissue • At the venular end of the capillary, forces are different to allow resorption of fluid back into the capillary
  • 10. When Injury Occurs • When an injury occurs Capillary Filtration Pressure (CHP) changes as a result of increased Tissue Oncotic Pressure (TOP), causing edema accumulation in the tissue • Read on to see why…
  • 11. When Injury Occurs • When an injury occurs, free proteins escape into the tissue as a result of increased capillary permeability, tissue debris, or blood vessel bleeding • This increases Tissue Oncotic Pressure (TOP) which draws fluid into the tissue resulting in edema and
  • 12. When Injury Occurs • Normally (no injury), 2/3 of the fluid leaving the capillary is reabsorbed into the capillary, and the rest is picked up by the lymphatic system • With an injury, this system is overloaded since more fluid is exiting the capillary than can be absorbed
  • 13. When Injury Occurs • In summary, capillary filtration pressure increases when an injury occurs, leading to fluid buildup in the tissues
  • 14. Reference • Knight and Draper, Therapeutic Modalities: The Art and Science