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Role of validated and standardized herbal products ; A scientific approach
1. R OLE OF VALIDATED AND
S TANDARDIZED H ERBAL
P RODUCTS -
A SCIENTIFIC APPROACH
Dr Capt Tanweer Alam
Head( AHP ) International Marketing
25th Oct 2011
Sun Moon Lake, Nantau, Taiwan
2. G ROWING I MPORTANCE
ď‚Ą Out of 252 drugs considered basic and essential
by WHO , 11% are exclusively from plant origin
and 28% are of synthetic origin but obtained
from natural precursors
ď‚Ą Eighty Five percent (85%) people in developing
countries still rely on traditional medicines as
first choice for human health care (WHO).
3. T HE COMPARISON OF SCOPE !
Total world population
Poultry : 19 Billion Total world population
Cattle : 1.5 billion Human: 6.88 Billion
Sheep and goat : 1.6 billion
Source: FAOSTAT website
4. H ERBAL M ARKET: A COMPARISON
Total Animal Health
Herbal Market
Total Global Herbal Market
100 Billion USD 1.5
Billion USD
Source: FAOSTAT website
& CLFMA REPORT 2009
9. G ROWING C REDENTIALS : S TANDARDIZATION &
B ETTER A NALYTICAL METHODS
10. G ROWING C REDENTIALS : S TANDARISATION &
B ETTER A NALYTICAL METHODS
A. paniculata Bacopa monnieri Zingiber officinale
11. G ROWING C REDENTIALS :
AVAILABLE T ECHNICAL B ACK - UPS
Total number of research papers listed on PubMed
containing the word "phytoconstituents."
12. G ROWING C REDENTIALS :
A RRAY OF H ERBAL M ONOGRAPHS
Publication and availability of authoritative
monographs by various organizations, improving
the scientific credibility of herbs.
13. G ROWING C REDENTIALS :
A RRAY OF H ERBAL M ONOGRAPHS
United States
Pharmacopoeia
( USP ) Europe Scientific
Cooperative
Indian Herbal on
Pharmacopoeia Phytotherapy
(ESCOP)
Confluence of
Herbal
Pharmacopoeia Chinese Herbal
British Herbal Pharmacopoeia
Pharmacopoeia
English Translation
of American Herbal
German Pharmacopoeia
Commissions ( AHP )
E monographs
14. INDIA
ď‚Ą 2,50,000 flowering plants world wide
 India – 8th largest country in natural plants
ď‚Ą One of the largest flora bio diversity
ď‚Ą 75% of the medicinal plants grow naturally
in India.
15. ď‚Ą Scientific approch of herbal product development
17. G ENUINENESS
Test for Foreign Matter
Contaminated
(i) Foreign organs: matter coming from
the source plant but not defined as the
drug.
(ii) Foreign elements: matter not coming
from the source plant and of either
vegetable or mineral origin. (viz,. Free from
contamination
Moulds, insects and other animal
contamination.)
19. G ENUINENESS
HPTLC Finger print
Phytochemical profile checked by
Chromotographic techniques.
The samples are chromotographed reference standards
of marker constituents.
22. E FFICACY
LC/MS DETECTION:
Powerful Tool for Organic Compound Analysis
Its application is oriented towards the specific detection and potential
entification of phytomarkers in the presence of other phytochemical
23. S AFETY
• Physico-chemical [ Moisture, Ash, Acid insoluble ash,,Silica (Sand)]
• Heavy metal residues (Pb, Cd, As, Hg)
• Mycotoxin residues
• Pesticide residues (organochloro pesticides and organophosphorous
pesticides).
• Organic volatile impurities (solvent residues-wherever applicable)
• Naturally occuring toxins (like pyrrolizidine, alkaloids, beta asarone,
cynogenic glycosides etc.)
• Microbial Analysis for specific pathogens
24. CONSISTENCY
Batch to batch consistency
S – STANDARD MIX
T1- TEST SAMPLE (BATCH NO. AP/07, 24 MONTHS OLD SAMPLE)
T2- TEST SAMPLE (BATCH NO. AP/01005, 18 MONTHS OLD SAMPLE)
T3- TEST SAMPLE (BATCH NO. AP/02001, 12 MONTHS OLD SAMPLE)
T4- TEST SAMPLE (BATCH NO. AP/02006, 6 MONTHS OLD SAMPLE)
T5- TEST SAMPLE (BATCH NO. AP/02010, 1 MONTH OLD SAMPLE)
25. A BRIEF
 India’s No 1 Herbal Veterinary company for
the last 60 years
ď‚Ą Pioneers in phyto-pharmaceuticals
ď‚Ą State-of-the-Art R&D with more than 100
qualified scientists
28. C ORPORATE S OCIAL
RESPONSIBILITY
 Quarterly journal called “Journal of Natural Remedies” dedicated to
Medicinal Plant research across the globe.
 A monthly magazine “Pashudhan”, dedicated to animal healthcare
since 35 years and
 Launched a web portal “vetsjobsindia.com”, developed exclusively for
communicating employment opportunities to vets.