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European Incubators in
Silicon Valley: the M31 case
Aldo Cocchiglia, CEO – M31 USA

Stanford Engineering School, January 3 2011
What’s in a name?


M31 is the code name for Andromeda
galaxy


M31 is a galaxy of technology stars


                                      2
What does M31 do?

M31 Italia turns innovative technologies into start-
ups.
M31 USA turns technology start-ups into successful
global companies.




                                                       3
Where and When




M31 Italia founded in Padova, Italy in 2006
Focus on incubation: working with entrepreneurs
from seed funding to corporate exits
M31 USA established in Silicon Valley in 2010
Initial focus: global expansion for Italian high-tech
companies including start-ups and larger high-
tech enterprises

                                                        4
M31 Operating Model

Venture incubation - office space
and office shared services

Funding – from seed
to 2nd + rounds

Management advisor– from
strategy to execution

Global Business Development –
from leads to contracts



                                    5
M31 Focus

Sectors we invest in: Medical Equipment, Embedded
Computing, Optical Systems, Software and Web,
Sensor Networks
Core competences: Innovative Product Development,
Strategic Management, Global Reach
Services provided: from incubation to management,
from international expansion to exit
Deal flow: affiliation with universities, research labs,
private companies, Angels, early-stage VCs., etc.
Typical investment size: € 50 K to 2.5 M, with
syndicate if needed

                                                           6
Our Value Proposition

M31 is different from:
Business Plan Competitions
We invest capital
Traditional Incubators
We provide more than just office
space and services
                                   M31 decodes the
Angels and early stage VCs         start-up DNA
Founders retain large equity
stakes and we co-manage the
company with them


                                                     7
M31 Portfolio
                     software & WEB,
                     sensor networks,
                                            wireless
                      I-net of things
                                            antennas


        biomedical
       instruments




                                                  WEB services
                                                   in eyecare
    embedded
electronics & PCs



                                                   WEB services




                     adaptive
                      optics


                                                                 8
Shareholders

Private Investors, including
academics, business managers and
entrepreneurs
TTVenture - Technology Transfer
Venture Capital Fund
M31 Management Team

Funds raised since 2007: $ 10 M
M31 investments:        $ 10 M



                                   9
Management Team

Ruggero Frezza
President, M31 Italia

Riccardo Fontanelli
COO, M31 Italia

Aldo Cocchiglia
CEO, M31USA

Mauro Odorico
Board Director, M31
Chief Investment Officer of TTVenture

Elisabetta Ghisini
CMO, M31 USA


                                        10
M31 USA

Global Expansion Services
• US entry planning
• Global expansion planning
• Start-up incubation in SV
• Innovation tours for Italian companies and university
programs
• Exit strategy and Fundraising support for additional
rounds
Gateway to Italian Technologies
• Technology scouting for US companies
• Partner/supplier scouting for US companies
• High-tech investments in Italy: start-up or product line
acquisitions

                                                             11
M31USA Clients



       M31 Portfolio
        Companies


                 University
  Italian       Technology
High-Tech         Transfer
Companies          Offices


                              12
M31 portfolio companies: the CenterVue case




                                              13
The CenterVue Case

Incorporated in April 2008 - first startup for M31
Develops hw & sw for cost-effective screening
programs to detect and treat ocular diseases
that bring to blindness
Shareholding: M31 46%, Seed investor 28%,
Founders & Management 26%
Total capital raised: $2.4M; headcount: 17
Developed two innovative devices approved by
FDA in 2010, and a Web software platform


                                                14
The CenterVue Case

The Eye Knowledge network: a Web
platform for eye care, i.e. online
continuing education, expert
consultation and telemedicine

MAIA: early detection and
management of Age Related
Macular Degeneration (AMD)

DRS: a fully automated, inexpensive,
retinal camera for large scale
screening of Diabetic Retinopathy
                                       15
The DRS

Takes digital photo of the back
of both eyes in 50 sec. and
transfers it to telemedicine
platform for remote diagnosis
Fully automated: requires no
installation, no training and no
operators

Sale price: less than half of any competitive product
Can be available at any health-care point nationwide
with no need for skilled operators
Allows for basic and large–scale data collection for
prevention of diabetes-related blindness

                                                   16
The DRS




          17
Highlights of the CenterVue Story

Major positive impact on social costs of
blindness in US and worldwide
Short development time and very limited
investment thanks to the “M31 model”
2010 sales: 120+ units
Estimated 2011 sales: 1700+ units in 60
countries for $25+M (64% in US)
Planning an exit via acquisition or IPO in
US within 2 -3 years
                                              18
M31 Italia Srl         M31 USA, LLC
               Via N. Tommaseo 77     4655 Old Ironsides Dr.
               35131 Padova – Italy   Santa Clara, CA 95054
               Ph: +39 049 781 1811   Ph: +1 408 988 8404
               www.m31.com            www.m31usa.com


         aldo.cocchiglia@m31.com



M31: Incubation of European Ideas,
with European R&D, European job creation
and US business development

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Aldo Cocchiglia - M31 - European Incubators in Silicon Valley - Stanford - Jan 3 2011

  • 1. European Incubators in Silicon Valley: the M31 case Aldo Cocchiglia, CEO – M31 USA Stanford Engineering School, January 3 2011
  • 2. What’s in a name? M31 is the code name for Andromeda galaxy M31 is a galaxy of technology stars 2
  • 3. What does M31 do? M31 Italia turns innovative technologies into start- ups. M31 USA turns technology start-ups into successful global companies. 3
  • 4. Where and When M31 Italia founded in Padova, Italy in 2006 Focus on incubation: working with entrepreneurs from seed funding to corporate exits M31 USA established in Silicon Valley in 2010 Initial focus: global expansion for Italian high-tech companies including start-ups and larger high- tech enterprises 4
  • 5. M31 Operating Model Venture incubation - office space and office shared services Funding – from seed to 2nd + rounds Management advisor– from strategy to execution Global Business Development – from leads to contracts 5
  • 6. M31 Focus Sectors we invest in: Medical Equipment, Embedded Computing, Optical Systems, Software and Web, Sensor Networks Core competences: Innovative Product Development, Strategic Management, Global Reach Services provided: from incubation to management, from international expansion to exit Deal flow: affiliation with universities, research labs, private companies, Angels, early-stage VCs., etc. Typical investment size: € 50 K to 2.5 M, with syndicate if needed 6
  • 7. Our Value Proposition M31 is different from: Business Plan Competitions We invest capital Traditional Incubators We provide more than just office space and services M31 decodes the Angels and early stage VCs start-up DNA Founders retain large equity stakes and we co-manage the company with them 7
  • 8. M31 Portfolio software & WEB, sensor networks, wireless I-net of things antennas biomedical instruments WEB services in eyecare embedded electronics & PCs WEB services adaptive optics 8
  • 9. Shareholders Private Investors, including academics, business managers and entrepreneurs TTVenture - Technology Transfer Venture Capital Fund M31 Management Team Funds raised since 2007: $ 10 M M31 investments: $ 10 M 9
  • 10. Management Team Ruggero Frezza President, M31 Italia Riccardo Fontanelli COO, M31 Italia Aldo Cocchiglia CEO, M31USA Mauro Odorico Board Director, M31 Chief Investment Officer of TTVenture Elisabetta Ghisini CMO, M31 USA 10
  • 11. M31 USA Global Expansion Services • US entry planning • Global expansion planning • Start-up incubation in SV • Innovation tours for Italian companies and university programs • Exit strategy and Fundraising support for additional rounds Gateway to Italian Technologies • Technology scouting for US companies • Partner/supplier scouting for US companies • High-tech investments in Italy: start-up or product line acquisitions 11
  • 12. M31USA Clients M31 Portfolio Companies University Italian Technology High-Tech Transfer Companies Offices 12
  • 13. M31 portfolio companies: the CenterVue case 13
  • 14. The CenterVue Case Incorporated in April 2008 - first startup for M31 Develops hw & sw for cost-effective screening programs to detect and treat ocular diseases that bring to blindness Shareholding: M31 46%, Seed investor 28%, Founders & Management 26% Total capital raised: $2.4M; headcount: 17 Developed two innovative devices approved by FDA in 2010, and a Web software platform 14
  • 15. The CenterVue Case The Eye Knowledge network: a Web platform for eye care, i.e. online continuing education, expert consultation and telemedicine MAIA: early detection and management of Age Related Macular Degeneration (AMD) DRS: a fully automated, inexpensive, retinal camera for large scale screening of Diabetic Retinopathy 15
  • 16. The DRS Takes digital photo of the back of both eyes in 50 sec. and transfers it to telemedicine platform for remote diagnosis Fully automated: requires no installation, no training and no operators Sale price: less than half of any competitive product Can be available at any health-care point nationwide with no need for skilled operators Allows for basic and large–scale data collection for prevention of diabetes-related blindness 16
  • 17. The DRS 17
  • 18. Highlights of the CenterVue Story Major positive impact on social costs of blindness in US and worldwide Short development time and very limited investment thanks to the “M31 model” 2010 sales: 120+ units Estimated 2011 sales: 1700+ units in 60 countries for $25+M (64% in US) Planning an exit via acquisition or IPO in US within 2 -3 years 18
  • 19. M31 Italia Srl M31 USA, LLC Via N. Tommaseo 77 4655 Old Ironsides Dr. 35131 Padova – Italy Santa Clara, CA 95054 Ph: +39 049 781 1811 Ph: +1 408 988 8404 www.m31.com www.m31usa.com aldo.cocchiglia@m31.com M31: Incubation of European Ideas, with European R&D, European job creation and US business development