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Down syndrome
1.
2.
3.
4.
5.
With Mosaic
Down syndrome some cells have an extra copy of chromosome 21, but not all.
6.
Mosaic Down
syndrome is caused by abnormal cell division after fertilization.
7.
occurs when
part of a chromosome 21becomes attached onto another chromosome, before or at conception.
8.
9.
10.
small ears
11.
small mouth
12.
upward slanting
eyes
13.
wide, short
hands with short fingers
14.
separated joints
between the bones of the skull
15.
decreased muscle
tone at birth
16.
protruding tongue
17.
18.
Age 40
= 1 in 106 chance
19.
20.
21.
340,000 people
in USA
22.
88% of cases
arise from mother's chromosome 21; 8% from father's chromosome 21; 2% from mitotic errors after fusion
23.
66-88% of
down patients have some level of hearing loss in at least one ear
24.
25.
26.
27.
28.
This test has
a greater risk for miscarriage than both Amniocentesis and CVS.
29.
30.
31.
32.
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