2. Swine flu(H1N1)

3. SWINE FLU

4. CONTENT’S
 About Swine flu.
 Causes of swine flu.
 Symptom’s.
Treatment.
About the drug.
 Prevention & precaution’s.
Conclusion.

5. SWINE FLU
1) What is swine flu…?
 Swine flu is a disease which caused by orthomyxovirus.
 Swine flu is an acute and highly spreading by contact
respiratory disease.
 Swine flu is also called as hog flu (or) pig flu.
 Now a days the swine influenza A [H1N1] virus that
has infected in human.
 Normally this virus is resistant to the antiviral drugs &
also resistant to vaccine.

6. 1920 1940 1960 1980 2000
H1N1
H2N2
H3N2
1918: “Spanish Flu” 1957: “Asian Flu” 1968: “Hong Kong Flu”
20-40 million deaths 1-4 million deaths
1-4 million deaths

7. The
Influenza Virus

9.  ClassifiCation :
 Swine influenza is known to be caused by influenza A
subtypes they are… 1) H1N1,
2) H1N2,
3) H3N1,
4) H3N2,
5) H2N3.

10. Reassortment in pigs
Reassortment
in humans
Pandemic
Influenza Virus
How it is caused and when…?
Reassortment in birds

11.  H1N1 is spread primarily through contact with an infected
person like the common flu.
 Routes of transmission are mainly through coughing or
sneezing. Also, the virus can survive on contaminated
surfaces for up to 2 hours.

12. What are the Symptoms of Swine
Flu …?
 aCCording to the CdC, like seasonal flu, symptoms
of swine flu infeCtions Can inClude:
 Fever.
 Cough.
 Runny nose or stuffy nose.
 Sore throat.
 Body aches.
 Headache.
 Chills.
 Vomiting.
 Aching muscles.
 Mild respiratory.

13. Serious Symptoms of Swine
Flu..,
 Acute respiratory distress.
 Bluish or gray skin color.
 Eye infections.
 Pneumonia.
 Viral pneumonia.
 Inflammation of the brain &heart.
 Vomiting.

14. TREATMENT
 Relenza [Zanamivir], Tami flu [Oseltamivir], amantidine
(symmetrel), rimantadine (Flumadine) are currently one
of the most powerful drugs against the Swine flu virus.
Treatment by 2 types.
 Isolation
 Anti-viral
treatment.

15. Isolation Precautions

17. About the drug…,
 GENERIC NAME : zanamivir
 BRAND NAME : Relenza
 DRUG CLASS AND MECHANISM :
Zanamivir is a neuraminidase inhibitor.
That prevents the spread of influenza A and B
viruses.
The viruses responsible for the "flu."
Neuraminidase is an enzyme that is required by
the influenza viruses to spread from infected
cells to healthy cells

18. Zanamivir blocks the action of neuraminidase
there by reducing the spread of influenza. Since
the spread of the viruses is prevented,
The symptoms and duration of infection are
reduced..
STORAGE: Store at room temperature,
15-30°C (59-86°F)
PREGNANCY:Zanamivir has not been
adequately evaluated in pregnant women.

19. SIDE EFFECTS:
The most frequent side effects are
headaches,
nausea,
cough,
vomiting and
dizziness
Ear, nose and throat infections may occur.
 Patients who have asthma or other breathing problems
do not use this drug.
DOSING:
Zanamivir is administered by oral inhalation.
 The recommended dose is two inhalations
(5 mg per inhalation) twice daily for five days.

20. • No vaccine available to protect humans from
swine flu
• Vaccine for human seasonal influenza does not
protect against H1N1 swine flu viruses due to
antigenic differences, but may provide partial
protection against swine H3N2 virus
vACCINATION

21. Preventive & Precautions measures
of swine flu…?
 If hot water is not available, use an alcohol-based
hand gel.
 Wash your hands frequently with soap & hot running
water.
 Get a regular seasonal flu vaccination.
 Avoiding contact with ill persons.
 Staying at home if you are sick, to avoid affecting

22. N-95 Filtering
Masks
Surgical
Masks
Personal Protective
Equipment
(PPE)

23. Preventive-measures

24. Preventive-measures

25. Conclusion
Be aWare OF sWine FLu (Pig FLu).......

26. Reference
 For the most current information on the H1N1 influenza
outbreak, visit http://www.cdc.gov/h1n1flu/
 http://www.who.int/csr/disease/swineflu/en/index.html
 International Committee on Taxonomy of Viruses. "The
Universal Virus Database, version 4: Influenza A".
http://www.ncbi.nlm.nih.gov/ICTVdb/ICTVdB/00.046.0.01.htm
l
 a b c d e f "Swine influenza". The Merck Veterinary Manual.
2008.
http://www.merckvetmanual.com/mvm/index.jsp?cfile=html/bc/1
. Retrieved on April 30, 2009.

27.  V Trifonov, H Khiabanian, B Greenbaum, R Rabadan (30
April 2009). "
The origin of the recent swine influenza A(H1N1) virus infectin
". Eurosurveillance 4 (17).
http://www.eurosurveillance.org/images/dynamic/EE/V14N1
7/art19193.pdf.
 Maria Zampaglione (April 29, 2009). "Press Release:
A/H1N1 influenza like human illness in Mexico and the USA:
OIE statement". World Organisation for Animal Health.
http://www.oie.int/eng/press/en_090427.htm. Retrieved on
April 29, 2009.
 Swine influenza World Health Organization 27 April 2009
 "Influenza A(H1N1) frequently asked questions". WHO.int.
http://www.who.int/csr/disease/swineflu/faq/en/index.html.
Retrieved on 2009-05-07.