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Drugs that Require an Antidote/Treatment
Phentolamine  Antimuscarinic, anticholinergic agents   Phentolamine   Antidepressants  (MAO inhibitors and tryamine-containing foods may lead to hypertensive crisis including symptoms of chest pain, severe headache, nuchal rigidity, nausea and vomiting, photosensitivity, and enlarged pupils)  Atropine, Pralidoxime  Anticholinesterases (Cholinergics), organophosphates   N-acetylcysteine Acetaminophen (Paracetamol)   Antidote/Treatments Drug/Toxin
Digoxin immune Fasb (Digibind), Stop digitalis, normalize K; lidocaine, anti-dig FAB fragments ( Digitoxin) Digitalis Immune FAB  Digoxin, digitoxin, Digitalis  Amyl nitrite, sodium nitrite, sodium thiosulfate Cyanide  Glucagon Beta blockers  Flumazenil Benzodiazepines Antidote/Treatments Drug/Toxin
CaEDTA,  Edetate calcium disodium, dimeraprol,  penicillamine ,  succimer Lead  Deferoxamine Iron  Mesna  Ifosfamide  (Adverse effects cause hemorrhagic cystitis) Leucovorin calcium Fluorouracil (5FU) Antidote/Treatments Drug/Toxin
Methelyn blue Methemoglobin  Leucovorin calcium  Methotrexate  (Adverse effects cause folic acid deficiency)  Ethanol, dialysis, fomepizole  Methanol, ethylene glycol (antifreeze)  Calcium Gluconate  Magnesium Sulfate  Sodium Bicarbonate Lithium Carbonate (Eskalith)  Antidote/Treatments Drug/Toxin
Phytonadione (Vitamin K),  fresh frozen plasma   Anticoagulant:  Warfarin (Coumadin)  NaHCO3 (nonspecific), Physostigmine  Tricyclic antidepressants (Anafranil, Tofranil)  Aminocaproic Acid ( Amicar)  Thrombolytics: t-PA, (Streptokinase, Urokinase)  Nalmefene, Naloxone Hydrochloride (Narcan), Naltrexone  Opioids, Narcotic Analgesics: Demerol and Morphine Sulfate, Heroin Antidote/Treatments Drug/Toxin
Alkalinize urine, dialysis  Salicylates  Dimercaprol (BAL), succimer  Arsenic, mercurym gold  Penicillamine  Copper, arsenic, gold  100% O2, hyperbaric O2  Carbon Monoxide  Protamine Sulfate Anticoagulant: Heparin  Antidote/Treatments Drug/Toxin
“ Nurses Informations” http://nursesinformations.blogspot.com

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Drugs/Toxins That Require An Antidote And Treatment

  • 1. Drugs that Require an Antidote/Treatment
  • 2. Phentolamine Antimuscarinic, anticholinergic agents Phentolamine Antidepressants (MAO inhibitors and tryamine-containing foods may lead to hypertensive crisis including symptoms of chest pain, severe headache, nuchal rigidity, nausea and vomiting, photosensitivity, and enlarged pupils) Atropine, Pralidoxime Anticholinesterases (Cholinergics), organophosphates N-acetylcysteine Acetaminophen (Paracetamol) Antidote/Treatments Drug/Toxin
  • 3. Digoxin immune Fasb (Digibind), Stop digitalis, normalize K; lidocaine, anti-dig FAB fragments ( Digitoxin) Digitalis Immune FAB Digoxin, digitoxin, Digitalis Amyl nitrite, sodium nitrite, sodium thiosulfate Cyanide Glucagon Beta blockers Flumazenil Benzodiazepines Antidote/Treatments Drug/Toxin
  • 4. CaEDTA, Edetate calcium disodium, dimeraprol, penicillamine , succimer Lead Deferoxamine Iron Mesna Ifosfamide (Adverse effects cause hemorrhagic cystitis) Leucovorin calcium Fluorouracil (5FU) Antidote/Treatments Drug/Toxin
  • 5. Methelyn blue Methemoglobin Leucovorin calcium Methotrexate (Adverse effects cause folic acid deficiency) Ethanol, dialysis, fomepizole Methanol, ethylene glycol (antifreeze) Calcium Gluconate Magnesium Sulfate Sodium Bicarbonate Lithium Carbonate (Eskalith) Antidote/Treatments Drug/Toxin
  • 6. Phytonadione (Vitamin K), fresh frozen plasma Anticoagulant: Warfarin (Coumadin) NaHCO3 (nonspecific), Physostigmine Tricyclic antidepressants (Anafranil, Tofranil) Aminocaproic Acid ( Amicar) Thrombolytics: t-PA, (Streptokinase, Urokinase) Nalmefene, Naloxone Hydrochloride (Narcan), Naltrexone Opioids, Narcotic Analgesics: Demerol and Morphine Sulfate, Heroin Antidote/Treatments Drug/Toxin
  • 7. Alkalinize urine, dialysis Salicylates Dimercaprol (BAL), succimer Arsenic, mercurym gold Penicillamine Copper, arsenic, gold 100% O2, hyperbaric O2 Carbon Monoxide Protamine Sulfate Anticoagulant: Heparin Antidote/Treatments Drug/Toxin
  • 8. “ Nurses Informations” http://nursesinformations.blogspot.com