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2
Forward Looking Statements

This presentation contains certain forward-looking statements. These
statements relate to future events or future performance and reflect
management’s expectations and assumptions regarding growth,
results of operations, performance and business prospects and
opportunities.     Such    forward-looking     statements     reflect
management’s current beliefs and are based on information
currently available to management.

 A number of factors could cause actual events to differ materially. In
evaluating these statements, prospective purchasers should
specifically consider various risks as more fully outlined in the
prospectus, a copy of which can be obtained online at
www.sedar.com.




                                                                              2
3
“There’s an epidemic of skin cancer”
     - Howard Rogers, Dermatologist, Lead on Medicare research

 Skin cancer strikes 1 in 5 in the U.S.1

 It is the most common form of cancer

 40-50% of Americans who live to 65 expected to get skin cancer 2

 Melanoma kills one person every hour in the US 3

 Melanoma is the #1 cancer killer of women 25-30 4

 Incidence of melanoma rising faster than any other cancer 5
                                                                     Melanoma is Deadly
                                                                      Accounts for 75% of
                                                                      skin cancer deaths6




                                                                                                3
4
Early detection vital to saving lives

      100   95% Melanoma Five Year Survival Rate by Tumor Stage 6


      80


      60


      40


      20
                                                              15%

        0

             Stage I        Stage II       Stage III        Stage IV
5
Early detection would save billions of dollars
 2 million Americans get skin cancer each year 7                  Cost of Treating Melanoma
                                                                  by Tumor Stage (per patient) 9
 Treating melanoma alone costs $1.5 billion                                                                   110.1
                                                    ($ US thousands)
  annually in the U.S. 8                                                                               105.5



 Advanced stage melanoma 22 times more
  costly to treat than early stage



                                                                                         35.4   38.3

                                                                           22.5   24.3

                                                            11.0    13.7
                                                     5.0

                                                    Early Stage                                         Late Stage
6
Current skin cancer detection methods limited
 Primary diagnosis done by GPs with varying
                                               Clinical Diagnosis   Histological Diagnosis
  levels of experience

 Full body examinations seldom conducted

 33.8% sensitivity for melanoma for GPs 10
  › Squamous Cell Carcinoma – 41.1%
  › Basal Cell Carcinoma – 63.9%

                                               Punch Biopsy
 Biopsies invasive and costly
  › Permanent scarring

 ~80% of biopsies test negative 11
7
Breakthrough early stage cancer detection system
     Initial Focus: Early detection of skin cancer

 Detects melanoma with 97% accuracy vs. 33.8%
  for primary clinical diagnosis
                                                        All forms of
                                                        Skin Cancer
 Developed by BC Cancer Agency and UBC

 Patented technology

 Exclusively licensed to Verisante Technology, Inc.




                                                       Gastrointestinal,
                                                       Lung, and Cervical
                                                       Cancers
8
Highly automated detection process
  Skin cancer: Verisante AuraTM


                                                     Near Infrared Raman
                Pathology on                         Spectroscopy
                every lesion scanned




          Differentiates between
          malignant and benign tissue               Handheld probe scans
                                                    for 21 biomarkers in
                                                    an instant



                   Provides data on chemical
                   composition of skin based   Rapid speed enables
                   on molecular vibrations     full body scans
9
Highly automated detection process
   Skin cancer: Verisante AuraTM



Safe, Non-invasive, Fast
                                   Increased survival rates

                                   Reduced treatment costs

                                   No unnecessary biopsies

                                   Reduced waiting times
Real time results
97% accurate for melanoma
91% for other skin cancers
10
Proven in clinical trials by the BC Cancer Agency
     Skin cancer: Verisante AuraTM

 6 year clinical study at Vancouver General
  Hospital’s Skin Care Center                      Melanoma
                                                                     97% sensitivity
 Focused on differentiating cancerous lesions                       “Percentage identified”
  from benign lesions                                                78% specificity
                                                                     “Confirmed by biopsy”
 1,000 skin lesions scanned

 Preliminary results published in 2008 based on   Cancerous and Precancerous Lesions
  274 lesions 12
                                                                     91% sensitivity
                                                                     “Percentage identified”

                                                                     75% specificity
                                                                     “Confirmed by biopsy”
11
Superior technology over competing systems
Verisante Aura™                      Scibase Inc.

                                     • Electrical Impedance Spectroscopy
 Proven technology                  • 98% sensitivity; specificity < 5%
                                     • Slightly invasive
 Detects all skin cancers           • 5 minutes per lesion
                                     • Large probe/expensive disposables

 97% Sensitivity; 78% Specificity   Mela Sciences
  for melanoma
                                     • Computerized Imaging Technology
                                     • FDA Panel recommends approval by narrow margin
 Measures 21 biomarkers             • Key Concern: too many false positives
                                     • 98% sensitivity; 9.5% specificity
 Virtually instant scan             • Large probe

                                     Lucid Inc.
 Non-invasive
                                     • Confocal Microscopy
 Tiny Probe                         • 10-20 min. per lesion
                                     • Dermatologist required
                                     • Large probe
 Inexpensive disposable covers
12
Endoscopic system enables detection of other cancers
      Verisante CoreTM

 Clinical studies underway at VGH for early detection of lung & colon cancer

Lung Cancer 13
World’s #1 cancer killer with
1.4 million deaths/year


Colon Cancer
#2 deadliest cancer in U.S.


Cervical Cancer
World’s #2 cause of cancer
deaths among women
13
Strong scientific pedigree
        Focused on developing systems for the early detection of cancer

Dr. Branko Palcic
Ph.D.


•   Honorary Professor, Dept. of Pathology and Laboratory Medicine, UBC
•   Founder, Cancer Imaging and Technology Departments, BC Cancer Agency
•   Co-inventor of LIFE-Lung device, used in over 150 major medical centers world-wide
•   Friesen-Rygiel Award for Outstanding Canadian Academic Discovery (1999)
•   King George V Silver Jubilee Cancer Research Fellow

Dr. Haishan Zeng
Ph.D.


• Senior Scientist, Integrative Oncology Dept. BC Cancer Agency
• Associate Professor, Dermatology and Skin Science, University of British Columbia
• Co-inventor - Verisante™ technology
14
Strong scientific pedigree
       Focused on developing systems for the early detection of cancer

Dr. David McLean
MD, FRCPC


•   Professor, Dept. of Dermatology and Skin Science, UBC
•   President, Cancer Prevention Institute of Canada
•   Former President, Canadian Dermatology Association
•   Co-inventor - Verisante™ technology

Dr. Harvey Lui
MD, FRCPC


•   Professor and Head, Dept. of Dermatology and Skin Science, UBC
•   Former Clinical Fellow, Massachusetts General Hospital, Harvard Medical School
•   University Killam Prize (2001)
•   Co-inventor - Verisante™ technology
15
Clear regulatory pathway to commercialization
   Skin cancer: Verisante AuraTM



2010                  2011                        2012              2013           2014          2015



       Production Prototype &
       Health Canada Approval          Marketing and Sales (Canada)


                      CE Mark          Marketing and Sales (EU, South Africa, Australia)


                      Clinical Study   Clinical Study
                      Prep.            USA
                                                         Approval    Marketing and Sales (USA)
16
Significant market potential with multiple end users
  Skin cancer: Verisante AuraTM




           Initial Geographic Markets                                Staged Rollout Strategy
   Recurring revenue from sale of disposable probe shields

                                                                                STEP 1
                                                                           Early adopters
                                                                       ~32,000 Dermatologists
 Canada
                              EU
  USA
                                                                                STEP 2
                                                                             Innovators
                                South                               ~950,000 General Practitioners
                                Africa
                                                                                STEP 3
                                                        Australia         Skin Care Clinics
                                                        NZ          Oncology and Imaging Clinics
                                                                               HMOs
17
Initial focus on early adopters and innovators
  Will drive broader market acceptance




    2000
                       Targeting 14%
                    penetration by year 5
    1600                                                    Dermatologists
                                                              United States
    1200

                                                              Canada, European Union, South Africa,
     800
                                                              Australia, New Zealand

     400


       0
            Yr. 1      Yr. 2    Yr. 3       Yr. 4   Yr. 5
18
Initial focus on early adopters and innovators
  Will drive broader market acceptance




   35000
                       Targeting 6%
   30000            penetration by year 5
                                                      General Practitioners
   25000
                                                        United States
   20000

   15000                                                Canada, European Union, South Africa,
                                                        Australia, New Zealand
   10000

    5000

        0
            Yr. 1    Yr. 2   Yr. 3    Yr. 4   Yr. 5
19
Experienced management
       Focus: controlling costs, accelerating product development & regulatory approval process

Thomas Braun
BA, JD, LLM – Chief Executive Officer


•   Public company experience
•   Extensive experience in executing M&As and raising capital
•   Advised high tech companies on international business transactions
•   Expertise in technology licensing
•   Member California Bar Association

Anna Trinh
B.Comm, LLB – Chief Financial Officer and Corporate Counsel


• Experience in counseling companies on regulatory and compliance filings
• M&A and financial transaction experience
• Practiced corporate securities law in private practice
20
Strong, independent Board of Directors

Joe Biegel                                            Chris Dennis
BS, MS (Medical Imaging)                              MBA


• Vice-President, Product Management & Marketing      • Former President, Comcare Health Services
• McKesson Medical Imaging Group                      • Senior positions with Angiotech
• Senior positions with Agfa Healthcare, Hewlett        Pharmaceuticals, Johnson & Johnson / Ortho
  Packard, Polaroid Medical Imaging                     Neutrogena


Karen Boodram                                         Jake Thiessen
BSc, MBA                                              Ph.D.


•   Vice-President, Business Development, SemBiosys   • Professor Emeritus, University of Toronto
•   Former Life Sciences Analyst, PI Financial        • Founding Director, School of Pharmacy and
•   More than 25 years healthcare experience            Health Sciences Campus, University of
                                                        Waterloo
•   Ten years with Novartis
21
Share Capital


   Common Shares                      46,188,117

   Common Shares (held by Founders)   14,700,000


   Total Common Shares Outstanding    60,888,117


   Warrants                           17,568,600

   Incentive Stock Options            3,545,000


   Fully Diluted Share Capital        82,001,717
22
Market Comparables

 Company                                                  Market Capitalization


 MELA Sciences, Inc. (NASDAQ: MELA)                       $93,000,000




 Novadaq (TSX: NDQ)                                       $126,000,000




 ALI Technologies Inc.
                                                          $530,000,000
 *Sold to McKesson (NYSE: MCK) in 2002 for $530 Million
23
Summary

 Breakthrough early stage skin cancer detection device

 Patented technology with exclusive worldwide license from BC Cancer Agency

 Clear regulatory pathway to commercialization with significant market potential

 Endoscopic device for early stage detection of lung, colon and cervical cancers in clinical trials

 Strong scientific pedigree and experienced management
24
End Notes
      References

1.  American Cancer Society. Cancer Facts & Figures 2009
2.  National Cancer Institute. Cancer Trends Progress Report 2007, Update April 2008
3.  American Cancer Society. Cancer Facts and Figures 2009
4.  Melanoma Research Foundation
5.  National Cancer Institute. SEER Cancer Statistics Review, 1975-2004
6.  National Center for Chronic Disease Prevention and Health Promotion
7.  Rogers HW, Weinstock MA, et al. Incidence Estimate of Non Melanoma Skin Cancer in the U.S., 2006, Archives of Dermatology 2010
8.  National Cancer Institute. Cancer Trends Progress Report 2007
9.  Doru Traian Alexandrescu. Melanoma Costs: A Dynamic Model Comparing Estimated Overall Costs of Various Clinical Stages,
    Dermatology Online Journal, Nov 2009
10. Heal CF, Raasch BA, Buettner PG, Weeden D. Accuracy of Clinical Diagnosis of Skin Lesions, British Journal of Dermatology 2009
11. Jones TP, Boiko PE, Piepkorn MW. Skin biopsy indications in primary care practice: a population-based study. JABFP 1996; 9:397–404.
12. Raman Spectroscopy for In Vivo Tissue Analysis and Diagnosis, Instrument Development to Clinical Applications, Journal of
    Innovation in Optical Health Sciences 2008
13. Cancer Research UK
14. National Cancer Institute. SEER Database, 1998 – 2000
15. Melamed MR, Flehinger BJ, Zamen MB, et al. Screening for early lung cancer: results of the Memorial Sloan-Kettering study In New
    York. Chest 86:44-53, 1984.
16. Cortese DA, Pairolero PC, Bergstralh EJ, et al. Roentgenographically occult lung cancer. A ten-year experience. J Thorac Cardiovasc
    Surg 86:373—80, 1983
25




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Vesrisante Technology

  • 1.
  • 2. 2 Forward Looking Statements This presentation contains certain forward-looking statements. These statements relate to future events or future performance and reflect management’s expectations and assumptions regarding growth, results of operations, performance and business prospects and opportunities. Such forward-looking statements reflect management’s current beliefs and are based on information currently available to management. A number of factors could cause actual events to differ materially. In evaluating these statements, prospective purchasers should specifically consider various risks as more fully outlined in the prospectus, a copy of which can be obtained online at www.sedar.com. 2
  • 3. 3 “There’s an epidemic of skin cancer” - Howard Rogers, Dermatologist, Lead on Medicare research  Skin cancer strikes 1 in 5 in the U.S.1  It is the most common form of cancer  40-50% of Americans who live to 65 expected to get skin cancer 2  Melanoma kills one person every hour in the US 3  Melanoma is the #1 cancer killer of women 25-30 4  Incidence of melanoma rising faster than any other cancer 5 Melanoma is Deadly Accounts for 75% of skin cancer deaths6 3
  • 4. 4 Early detection vital to saving lives 100 95% Melanoma Five Year Survival Rate by Tumor Stage 6 80 60 40 20 15% 0 Stage I Stage II Stage III Stage IV
  • 5. 5 Early detection would save billions of dollars  2 million Americans get skin cancer each year 7 Cost of Treating Melanoma by Tumor Stage (per patient) 9  Treating melanoma alone costs $1.5 billion 110.1 ($ US thousands) annually in the U.S. 8 105.5  Advanced stage melanoma 22 times more costly to treat than early stage 35.4 38.3 22.5 24.3 11.0 13.7 5.0 Early Stage Late Stage
  • 6. 6 Current skin cancer detection methods limited  Primary diagnosis done by GPs with varying Clinical Diagnosis Histological Diagnosis levels of experience  Full body examinations seldom conducted  33.8% sensitivity for melanoma for GPs 10 › Squamous Cell Carcinoma – 41.1% › Basal Cell Carcinoma – 63.9% Punch Biopsy  Biopsies invasive and costly › Permanent scarring  ~80% of biopsies test negative 11
  • 7. 7 Breakthrough early stage cancer detection system Initial Focus: Early detection of skin cancer  Detects melanoma with 97% accuracy vs. 33.8% for primary clinical diagnosis All forms of Skin Cancer  Developed by BC Cancer Agency and UBC  Patented technology  Exclusively licensed to Verisante Technology, Inc. Gastrointestinal, Lung, and Cervical Cancers
  • 8. 8 Highly automated detection process Skin cancer: Verisante AuraTM Near Infrared Raman Pathology on Spectroscopy every lesion scanned Differentiates between malignant and benign tissue Handheld probe scans for 21 biomarkers in an instant Provides data on chemical composition of skin based Rapid speed enables on molecular vibrations full body scans
  • 9. 9 Highly automated detection process Skin cancer: Verisante AuraTM Safe, Non-invasive, Fast Increased survival rates Reduced treatment costs No unnecessary biopsies Reduced waiting times Real time results 97% accurate for melanoma 91% for other skin cancers
  • 10. 10 Proven in clinical trials by the BC Cancer Agency Skin cancer: Verisante AuraTM  6 year clinical study at Vancouver General Hospital’s Skin Care Center Melanoma 97% sensitivity  Focused on differentiating cancerous lesions “Percentage identified” from benign lesions 78% specificity “Confirmed by biopsy”  1,000 skin lesions scanned  Preliminary results published in 2008 based on Cancerous and Precancerous Lesions 274 lesions 12 91% sensitivity “Percentage identified” 75% specificity “Confirmed by biopsy”
  • 11. 11 Superior technology over competing systems Verisante Aura™ Scibase Inc. • Electrical Impedance Spectroscopy  Proven technology • 98% sensitivity; specificity < 5% • Slightly invasive  Detects all skin cancers • 5 minutes per lesion • Large probe/expensive disposables  97% Sensitivity; 78% Specificity Mela Sciences for melanoma • Computerized Imaging Technology • FDA Panel recommends approval by narrow margin  Measures 21 biomarkers • Key Concern: too many false positives • 98% sensitivity; 9.5% specificity  Virtually instant scan • Large probe Lucid Inc.  Non-invasive • Confocal Microscopy  Tiny Probe • 10-20 min. per lesion • Dermatologist required • Large probe  Inexpensive disposable covers
  • 12. 12 Endoscopic system enables detection of other cancers Verisante CoreTM  Clinical studies underway at VGH for early detection of lung & colon cancer Lung Cancer 13 World’s #1 cancer killer with 1.4 million deaths/year Colon Cancer #2 deadliest cancer in U.S. Cervical Cancer World’s #2 cause of cancer deaths among women
  • 13. 13 Strong scientific pedigree Focused on developing systems for the early detection of cancer Dr. Branko Palcic Ph.D. • Honorary Professor, Dept. of Pathology and Laboratory Medicine, UBC • Founder, Cancer Imaging and Technology Departments, BC Cancer Agency • Co-inventor of LIFE-Lung device, used in over 150 major medical centers world-wide • Friesen-Rygiel Award for Outstanding Canadian Academic Discovery (1999) • King George V Silver Jubilee Cancer Research Fellow Dr. Haishan Zeng Ph.D. • Senior Scientist, Integrative Oncology Dept. BC Cancer Agency • Associate Professor, Dermatology and Skin Science, University of British Columbia • Co-inventor - Verisante™ technology
  • 14. 14 Strong scientific pedigree Focused on developing systems for the early detection of cancer Dr. David McLean MD, FRCPC • Professor, Dept. of Dermatology and Skin Science, UBC • President, Cancer Prevention Institute of Canada • Former President, Canadian Dermatology Association • Co-inventor - Verisante™ technology Dr. Harvey Lui MD, FRCPC • Professor and Head, Dept. of Dermatology and Skin Science, UBC • Former Clinical Fellow, Massachusetts General Hospital, Harvard Medical School • University Killam Prize (2001) • Co-inventor - Verisante™ technology
  • 15. 15 Clear regulatory pathway to commercialization Skin cancer: Verisante AuraTM 2010 2011 2012 2013 2014 2015 Production Prototype & Health Canada Approval Marketing and Sales (Canada) CE Mark Marketing and Sales (EU, South Africa, Australia) Clinical Study Clinical Study Prep. USA Approval Marketing and Sales (USA)
  • 16. 16 Significant market potential with multiple end users Skin cancer: Verisante AuraTM Initial Geographic Markets Staged Rollout Strategy Recurring revenue from sale of disposable probe shields STEP 1 Early adopters ~32,000 Dermatologists Canada EU USA STEP 2 Innovators South ~950,000 General Practitioners Africa STEP 3 Australia Skin Care Clinics NZ Oncology and Imaging Clinics HMOs
  • 17. 17 Initial focus on early adopters and innovators Will drive broader market acceptance 2000 Targeting 14% penetration by year 5 1600 Dermatologists United States 1200 Canada, European Union, South Africa, 800 Australia, New Zealand 400 0 Yr. 1 Yr. 2 Yr. 3 Yr. 4 Yr. 5
  • 18. 18 Initial focus on early adopters and innovators Will drive broader market acceptance 35000 Targeting 6% 30000 penetration by year 5 General Practitioners 25000 United States 20000 15000 Canada, European Union, South Africa, Australia, New Zealand 10000 5000 0 Yr. 1 Yr. 2 Yr. 3 Yr. 4 Yr. 5
  • 19. 19 Experienced management Focus: controlling costs, accelerating product development & regulatory approval process Thomas Braun BA, JD, LLM – Chief Executive Officer • Public company experience • Extensive experience in executing M&As and raising capital • Advised high tech companies on international business transactions • Expertise in technology licensing • Member California Bar Association Anna Trinh B.Comm, LLB – Chief Financial Officer and Corporate Counsel • Experience in counseling companies on regulatory and compliance filings • M&A and financial transaction experience • Practiced corporate securities law in private practice
  • 20. 20 Strong, independent Board of Directors Joe Biegel Chris Dennis BS, MS (Medical Imaging) MBA • Vice-President, Product Management & Marketing • Former President, Comcare Health Services • McKesson Medical Imaging Group • Senior positions with Angiotech • Senior positions with Agfa Healthcare, Hewlett Pharmaceuticals, Johnson & Johnson / Ortho Packard, Polaroid Medical Imaging Neutrogena Karen Boodram Jake Thiessen BSc, MBA Ph.D. • Vice-President, Business Development, SemBiosys • Professor Emeritus, University of Toronto • Former Life Sciences Analyst, PI Financial • Founding Director, School of Pharmacy and • More than 25 years healthcare experience Health Sciences Campus, University of Waterloo • Ten years with Novartis
  • 21. 21 Share Capital Common Shares 46,188,117 Common Shares (held by Founders) 14,700,000 Total Common Shares Outstanding 60,888,117 Warrants 17,568,600 Incentive Stock Options 3,545,000 Fully Diluted Share Capital 82,001,717
  • 22. 22 Market Comparables Company Market Capitalization MELA Sciences, Inc. (NASDAQ: MELA) $93,000,000 Novadaq (TSX: NDQ) $126,000,000 ALI Technologies Inc. $530,000,000 *Sold to McKesson (NYSE: MCK) in 2002 for $530 Million
  • 23. 23 Summary  Breakthrough early stage skin cancer detection device  Patented technology with exclusive worldwide license from BC Cancer Agency  Clear regulatory pathway to commercialization with significant market potential  Endoscopic device for early stage detection of lung, colon and cervical cancers in clinical trials  Strong scientific pedigree and experienced management
  • 24. 24 End Notes References 1. American Cancer Society. Cancer Facts & Figures 2009 2. National Cancer Institute. Cancer Trends Progress Report 2007, Update April 2008 3. American Cancer Society. Cancer Facts and Figures 2009 4. Melanoma Research Foundation 5. National Cancer Institute. SEER Cancer Statistics Review, 1975-2004 6. National Center for Chronic Disease Prevention and Health Promotion 7. Rogers HW, Weinstock MA, et al. Incidence Estimate of Non Melanoma Skin Cancer in the U.S., 2006, Archives of Dermatology 2010 8. National Cancer Institute. Cancer Trends Progress Report 2007 9. Doru Traian Alexandrescu. Melanoma Costs: A Dynamic Model Comparing Estimated Overall Costs of Various Clinical Stages, Dermatology Online Journal, Nov 2009 10. Heal CF, Raasch BA, Buettner PG, Weeden D. Accuracy of Clinical Diagnosis of Skin Lesions, British Journal of Dermatology 2009 11. Jones TP, Boiko PE, Piepkorn MW. Skin biopsy indications in primary care practice: a population-based study. JABFP 1996; 9:397–404. 12. Raman Spectroscopy for In Vivo Tissue Analysis and Diagnosis, Instrument Development to Clinical Applications, Journal of Innovation in Optical Health Sciences 2008 13. Cancer Research UK 14. National Cancer Institute. SEER Database, 1998 – 2000 15. Melamed MR, Flehinger BJ, Zamen MB, et al. Screening for early lung cancer: results of the Memorial Sloan-Kettering study In New York. Chest 86:44-53, 1984. 16. Cortese DA, Pairolero PC, Bergstralh EJ, et al. Roentgenographically occult lung cancer. A ten-year experience. J Thorac Cardiovasc Surg 86:373—80, 1983