1. Chapter 4 – Cellular Metabolism Cellular metabolism enables the organism to grow.

2. You are responsible for the following figures and tables : Fig. 4.14 - metabolic processes, anabolic and catabolic. Fig. 4.1, 4.2, 4.3 – Macromolecules. Fig. 4.4 - control of metabolism is achieved by enzymes. -see table summary in the attached lecture handout - Fig. 4.5 - metabolism occurs complex biochemical pathways. Fig. 4.15 - Metabolic reactions can be regulated by feedback mechanism. Read TB, p.108, on 'cellular respiration'. Fig. 4.6 - Cellular respiration consists of 3 biochemical pathways. -see table summaries in the attached lecture handout - -see also Ch.9 regarding ‘oxygen debt’ resulting in the synthesis of lactate instead of pyruvate- Fig. 4.17, 4.18 - RNA and DNA. Fig. 4.24 – DNA. Fig. 4.22 - transcription – translation Fig. 4.25 - Mutation Fig. 4.26 - Explain PKU.

13. Release of Chemical Energy During Cellular Respiration in a Muscle Cell Fig. 4.6

16. CELLULAR RESPIRATION = Need for O 2 and Release of CO 2 as waste from tissues GLYCOLYSIS CONVERSION STEP CITRIC ACID CYCLE ETC LOCATION cytoplasm mitochondria Mitochondrial matrix mitochondrial inner membrane O 2 Required? NO yes yes yes Starting Product glucose (6-C) 2 pyruvates (2 x 3C) Acetyl CoA (2 x 2C) 10 NADH 2 FADH 2 End- Products 2 pyruvates (2 x 3-C) 2 -4 ATP 2 NADH 2 Acetyl CoA 2 NADH 2 CO 2 6 NADH 2 FADH 2 2-4 ATP 4 CO 2 30 ATP 2-4 ATP 2-4 ATP TOTAL 34-38 ATP

29. Transcription (Figure 4.22)