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Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




Using Public Relations to
Launch, Grow and Extend
Your Brands

PROJECT BACKGROUND

 While Public Relations has long been used as a marketing
 tool by the pharmaceutical and biotechnology industries, its               Benchmarking Report
 ability to reach consumers has never been greater. However,                    at-a-Glance
 field research suggests few companies utilize the full
 potential of Public Relations campaigns throughout the
                                                                                Featured Study Participants
 entire product lifecycle – from preparing and launching to                     •   Abbott Laboratories
 growing and extending a brand.                                                 •   AstraZeneca
                                                                                •   AtheroGenics
 New technologies and market changes have greatly                               •   Boehringer Ingelheim
 expanded the reach and potential of cost-efficient Public                      •   Boiron
 Relations through websites, online social networks, blogs                      •   Cubist Pharmaceuticals
 and traditional media sources. These mediums have joined                       •   Emcure
 the traditional press release as effective and low-cost                        •   Farmasa Schwabe
 methods that help drive sales.                                                 •   Gebauer Company
                                                                                •   Genentech
 This research identifies which Public Relations activities                     •   Jazz Pharmaceuticals
 most effectively educate and inform consumers at different                     •   Johnson & Johnson
 points in a product's lifecycle. The report also delivers                      •   Merck Serono
 insights into the most effective Public Relations channels,                    •   Novartis
 tactics and calls-to-action for reaching consumers of                          •   Novo Nordisk
 pharmaceutical products. Four case studies of successful                       •   Pfizer
 products are included in this report to highlight Public                       •   Solvay
 Relations tactics at different lifecycle stages: Slentrol                      •   Wyeth
 (product launch), Flomax (brand-building), Nexium (product




Best Practices, LLC © (919) 403-0251                                                                          1
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




 maturity) and Fluvirin (patent expiration).
                                                                                     Industry Analysis
                                                                          18 benchmark companies representing
 This report’s objectives include:
                                                                          the biopharmaceutical industry
                                                                          participated in this study.
         •    Assessing Public Relations strategies and tactics
              that are most effective at different lifecycle
                                                                                    Information Types
              stages
                                                                          •     57 Information Graphics
         •    Identifying Public Relations tools and calls-to-            •     29 Data Graphics
                                                                          •     600+ Metrics
              action that are most effective
                                                                          •     35 Best Practices
                                                                          •     28 Executive Narratives
         •    Providing case analogs that reveal effective
              practices
                                                                                      Report Length
         •    Revealing innovative practices                              •     108 pages

 Topics covered in this study include:

         •    Public Relations strategies and tactics that are most effective at different lifecycle
              stages

         •    The most effective Public Relations tools and calls-to-action

         •    Case studies that reveal valuable Public Relations practices

         •    Successful website resources for consumers

         •    Ideal budget ratios and performance measurements

         •    Lessons learned and best practices




STUDY METHODOLOGY

 This report comprises quantitative data and insights drawn from surveyed executives at 18 top
 pharmaceutical companies. This research also features deep-dive interviews with selected
 executives at seven of these companies. The report profiles executives, directors and managers
 in Marketing and Public Relations and uncovers their recommendations for better aligning
 Public Relations activities and tactics with the different stages of a product’s lifecycle. In
 addition, this report provides leaders with insights into performance measurements for Public
 Relations campaigns and those web-based resources that best engage patients.




Best Practices, LLC © (919) 403-0251                                                                            2
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




REPORT STRUCTURE AND ORGANIZATION
 The project findings are organized into an executive summary, six topical chapters and an
 appendix. Following is a description of each section:

    •       Executive summary: Explains the survey methodology, identifies participating
            companies and reports key findings.

    •       Topical chapters: Features an overview of Optimal Use of Public Relations Tools and
            explores Public Relations approaches during each of the major lifecycle stages: Pre-
            Launch, Launch, Brand-Building, Late-Life Management and Patent Expiration
            Management. Four case studies are highlighted.

    •       Appendix: Underlines Public Relations lessons learned and sets out general good
            practices.



SAMPLE FINDINGS
    Among the findings that emerged from this research are the following:

        •    Public Relations Strategies, Tools and Tactics Can Be Employed
             Across the Product Lifecycle: Field research identified effective uses of Public
             Relations throughout the product lifecycle. Moreover, more Public Relations forms
             proved effective than any one brand has sought to employ. This suggests that Public
             Relations tools may be underutilized across all lifecycle stages.

        •    Public Relations Is a Cornerstone of Market-Entry Launch and
             Brand-Building: Field research revealed a “holy trinity” for Public Relations
             specialists. The three aspects of this operational strategy are human-interest positioning,
             lifestyle positioning and family relevance positioning. Public Relations campaigns that
             touch these groups tend to engage consumers and win media attention.

        •    Public Relations Strategies, Tools and Tactics Can Profitably Extend
             the Brand During Its Later Life: Certain Public Relations tactics prove very
             useful for targeting new sub-populations that are under-served or newly served by the
             brand. Social networking communities are effective ways for patients, family members
             and friends to share information and resources and offer support about a common
             medical condition.




Best Practices, LLC © (919) 403-0251                                                                       3
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




      •    Public Relations Can Help Build a Bridge from First-Generation to
           Next-Generation Blockbuster: Building Bridges: Integrated Public Relations
           and communication strategies helped AstraZeneca and Eli Lilly build sturdy bridges
           from Prilosec to Nexium and from Prozac to Cymbalta. This “bridge building” requires
           good planning and, ideally, should commence at the back end of the first-generation
           product’s lifecycle.

            Timing of the Bridge Building: Field findings revealed that successor products
            generally should commence Public Relations two years prior to the new product’s
            global launch. Some participants recommended three years lead time.

      •    New Technologies Create New Public Relations Opportunities: Social
           networking sites – such as Facebook, MySpace or disease-specific sites, like
           DepNet.com for depression sufferers – create links between brands and patients. Savvy
           communication experts are engaging these social networks throughout all stages of a
           brand’s lifecycle.




DATA SECTION EXCERPTS
 PR Effectiveness, Timing and Budget (an Excerpt)

 Public Relations tools benefit all phases of the product lifecycle. However, research participants
 identify the pre-launch, launch and growth phases as the highest-impact lifecycle stages for
 Public Relations influence and effectiveness.
                                                                                “Now along the span of the
 As one interviewed director said, “The first few years is where it             (product) life, you are evaluating
 [Public Relations] matters because that’s when you’re creating your            how many competitors there
                                                                                are, what is the market share,
 market share and that’s when you’re dominating. The more you                   what is their share of voice and
 wait, the less it’s effective because decisions have made habits;              what share of voice you want. If
                                                                                you want to become the leader
 doctors have decided already what they’re prescribing.”                        of share of voice and you want
                                                                                to steal market share, then you
 Still, nearly 50 percent of companies reported Public Relations                have to speak louder than
 effectiveness during product maturity, and 16 percent reported                 them.”
                                                                                         -Interviewed Executive Director,
 Public Relations tools to be effective during product decline.                                         Communications




Best Practices, LLC © (919) 403-0251                                                                                    4
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




                Pre-Launch, Launch & Growth Phases Benefit Greatly from PR
              Rate how effective your public relation campaigns have been during the
              following stages of the product’s lifecycle:

                                            Percentage of N respondents for Each
     Total Benchmark Class                                 Stage
                                                                                       Average Effectiveness for Each Stage
                                             Highly                         Highly     Highly                             Highly
                                           Ineffective                     Effective Ineffective                         Effective
                                                                                                                 Top 2 Boxes
   Public Relations Effectiveness     N        1          2     3     4       5               1    2       3         4           5



   Pre-Launch                         14      0%         0%    7%    43%    50%                                             93%
                                                                                                                         4.428571


   Launch                             15      0%         0%    7%    20%    73%
                                                                                                                           93%
                                                                                                                         4.666667

   Growth ( 1 - 5 years post-launch
                                      16      0%         0%    0%    56%    44%                                          100%
   )
                                                                                                                           4.4375

   Mature ( 5 years post - launch to
                                     15       0%         7%    47%   20%    27%                                      47%
   Patent Expiration )
                                                                                                                         3.666667

   Decline ( Post - Patent Expiration                                                                          16%
                                      13     23%         38%   23%   8%      8%
   )
                                                                                                                         2.384615




        Figure 2.21: Pre-Launch, Launch & Growth Phases Benefit Greatly From
                                     Public Relations




 Public Relations spending is a “highly leveraged” marketing investment, meaning that a
 relatively small investment can provide high returns. Consequently, Public Relations investment
 ratios – as a percent of total marketing –consistently comprise 20-25 percent of budget until a
 product nears patent expiration, when most marketing expenditures are cut.

 One interviewed executive offered the opinion that “Big pharma -- with a lot of foresight --will
 fund their brands until the patent expires. Some other pharma will have to switch funds from one
 brand to a new brand and have to deal with less money and will only tend to fund the first year
 or the first two years, and that’s a bit of a mistake.”




Best Practices, LLC © (919) 403-0251                                                                                                 5
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




 General Good Practices (an Excerpt)

 Public Relations tactics and tools are broad-reaching. Over time, Public Relations forms have
 proliferated – all targeted at reaching core influence groups like physicians, patients and media.
 Public Relations uses information-based calls-to-action to send the target audiences to resources
 of education, information or expertise.




                    PR Tools Help Educate & Inform The Market


                                                   Growth / Brand                               Transition /
             Pre-Launch/             Launch                                        Maturity       Decline
                                                      Building
             Development



          Press
         Release
                                                       CALLS TO ACTION


                                     Physicians                           Call
                                                                                     Advocacy
       Audio PR                                                          Centers
                                                                                      Groups
                           TARGETS




                                                                                                     You
                                      Patients                                                       Tube
        Advertorial
                                                                                       Ask
        Video PR                       Media                             Corp or     Your MD
                                                                          Brand                    Social
                                                                                                  Networks
       Info Forum                      Blogs                             Website




      Figure 8.1: Public Relations Tools Help Educate and Inform the Market


 Many strategies and tactics have relevance for products across all lifecycle phases, but these
 practices are most effective for brands at launch and growth phases. However, the tactics must
 fit the individual product. Integrated communication strategies are essential in coordinating
 campaigns directed at different target groups.

              •       Family-Related Public Relations Can Help With Key Sup-Populations:
                      Family-oriented Public Relations can be a useful approach in engaging key sub-
                      populations by age, gender and ethnicity.




Best Practices, LLC © (919) 403-0251                                                                           6
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




              •     Seed Public Relations with Insights About Personal Risk: Employ Public
                    Relations tools to help patients assess their personal risk for a specific medical
                    condition.

              •     Include Diagnostic Tools on Product’s Web Site: Seed websites with useful
                    online diagnostic tools to educate and expedite change.

              •     Seed Web Site with Consumer Incentives: Populate brand websites with
                    incentives (coupons, samples, co-pay assistance, contests, etc.) to engage
                    consumers.

              •     Use Patient Stories to Attract Different Groups: Use patient stories in a
                    product’s Public Relations that cut across different patient groups and target
                    high growth sub-populations.




ABOUT BENCHMARKINGREPORTS.COM
 BenchmarkingReports.com is a service of Best Practices, LLC, world-leader in benchmarking
 research and analysis. BenchmarkingReports.com provides vital insights and data from our
 primary research at a fraction of original project cost.

 Best Practices, LLC has conducted pioneering benchmarking research for top companies since
 1991, providing clients with "Access and Intelligence for Achieving World-Class Excellence."
 To learn how we can help you find solutions to your current business issues, visit our site at
 www.best-in-class.com.




Best Practices, LLC © (919) 403-0251                                                                     7
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




TABLE OF CONTENTS
Executive Summary ....................................................................................................................... 6

INTRODUCTION.............................................................................................................................. 6

RESEARCH APPROACH ................................................................................................................ 8

PARTICPANT DEMOGRAPHICS.................................................................................................... 8

DEFINITIONS AND ABBREVIATIONS.......................................................................................... 10

REPORT STRUCTURE AND ORGANIZATION............................................................................ 10

KEY FINDINGS.............................................................................................................................. 10

Using Public Relations Tools for Optimal Advantage.............................................................. 14

PUBLIC RELATIONS CALLS-TO-ACTION ................................................................................... 22

RESOURCES AND SUPPORT SERVICES .................................................................................. 27

EFFECTIVENESS, TIMING AND BUDGET .................................................................................. 33

Pre-Launch ................................................................................................................................... 40

Launch .......................................................................................................................................... 58

CASE STUDY SPOTLIGHT: SLENTROL...................................................................................... 68

Brand-Building ............................................................................................................................. 74

CASE STUDY SPOTLIGHT: FLOMAX.......................................................................................... 78

Late-Life Management ................................................................................................................. 86

CASE STUDY SPOTLIGHT: NEXIUM........................................................................................... 91

Patent Expiration Management ................................................................................................ 101

CASE STUDY SPOTLIGHT: FLUVIRIN ...................................................................................... 102

Lessons Learned........................................................................................................................ 105

GENERAL GOOD PRACTICES .................................................................................................. 105

ENGAGE, INFORM AND EDUCATE........................................................................................... 106

TAILOR LATE-STAGE TACTICS TO REACH SELECT SUB-POPULATION ............................ 107

BRIDGE THE GAP BETWEEN PRODUCT GENERATIONS ..................................................... 107




Best Practices, LLC © (919) 403-0251                                                                                                                   8
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




TABLES AND FIGURES
Table 1.1: Participating Companies ................................................................................................. 8

Figure 1.1: Participant Job Titles ..................................................................................................... 9

Figure 1.2: Benchmark Partners’ Experience .................................................................................. 9

Figure 2.1: Apply Public Relations Tools and Tactics Throughout the Lifecycle ........................... 14

Figure 2.2: Public Relations Tool Effectiveness Changes Over the Brand Lifecyle ...................... 15

Figure 2.3: Media Interviews Get Company’s Message Out Best ................................................. 16

Figure 2.4: Blogs and Social Networks Get Message Out in New Ways ...................................... 17

Figure 2.5: Patient Groups, Human-Interest Key to Informing Patients and Family...................... 18

Figure 2.6: Public Relations Positioning Tactics Offer Brand Teams Many Options..................... 19

Figure 2.7: Human-Interest Stories Resonate with Patients, Media.............................................. 20

Figure 2.8: Tactical Elements Appealing to Consumers Rated Best............................................. 21

Figure 2.9: Ask Physician About Condition Rates Highest ............................................................ 22

Figure 2.10: Public Relations Calls-To-Action Direct Consumers to Experts and Expertise......... 23

Figure 2.11: Inform and Inspire Consumers to Take Action on Their Own Behalf ........................ 24

Figure 2.12: Web-Based Calls-To-Action Direct Patients to Resources ....................................... 25

Figure 2.13: Medical Condition Websites Are Most Highly Rated ................................................. 26

Figure 2.14: Brand Websites Have More Options to Engage Consumers .................................... 27

Figure 2.15: Consumers Relate Well to Patient Stories ................................................................ 28

Figure 2.16: Best Web-Based Resouces Inform and Engage Patients......................................... 29

Figure 2.17:Testimonials Offer Valuable Hope and Tips for Patients............................................ 30

Figure 2.18: Patient Advocacy Groups Are Key Partners.............................................................. 31

Figure 2.19: Key Public Relations Support Resources Help Inform Patients ................................ 32

Figure 2.20: Trusted Information Sources Are Best Support Service............................................ 33

Figure 2.21: Pre-Launch, Launch and Growth Phases Benefit Greatly From Public
Relations ........................................................................................................................................ 34

Figure 2.22: Public Relations Budgets as a Percentage of Annual Marketing Spend................... 35




Best Practices, LLC © (919) 403-0251                                                                                                                    9
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




Figure 2.23: Measuring Public Relations Is a Double-Edged Sword............................................. 36

Figure 2.24: Public Relations Performance Metrics Are Critical but Imprecise ............................. 37

Figure 2.25: Begin Public Relations Early to Bridge From One Brand to Successor .................... 38

Figure 3.1: Public Relations Can Creat Buzz for New Treatment Paradigms ............................... 39

Figure 3.2: Formulas for Bringing Non-Intuitive Mechanism-of-Action Medicines to Market......... 41

Figure 3.3: Public Relations Tool Effectiveness at Pre-Launch..................................................... 42

Figure 3.4: Employ Public Relations to Reach Consumers Through Patient Advocacy
Groups ........................................................................................................................................... 43

Figure 3.5: Early Public Relations Guides Consumers to Trusted Third-Party
Informational Resources ................................................................................................................ 44

Figure 3.6: Introduce New Medical Ideas through Third-Party Expertise: Cymbalta..................... 45

Figure 3.7: Inform Consumers Through PR, Educational Messages and Personal Stories:
Cymbalta ........................................................................................................................................ 46

Figure 3.8: Shaping the Market for Successful Entry of New Products: Rituxin............................ 47

Figure 3.9: Early Advisory Board Harvests Insights and Seeds New Ideas .................................. 48

Figure 3.10: Dare to Kick-Start Debate Before Full Clinical Data are Available ............................ 50

Figure 3.11: Pre-Launch Scientific Discussion – But Don’t Promt Off-Label................................. 51

Figure 3.12: Pre-Launch Scientific Communications..................................................................... 52

Figure 3.13: B-Cell Dinners: Use Peer-to-Peer Discussions to Extend Science ........................... 53

Figure 3.14: Seminars and Congresses Extend Message to Broader Audience .......................... 54

Figure 3.15: Carefully Manage Expectations Pre-Launch ............................................................. 55

Figure 3.16: Carefully Manage Expectations Post-Launch............................................................ 56

Figure 3.17: Blueprint for Market-Entry Success ........................................................................... 57

Figure 4.1: Using Experts, Media and Ed Events to Educate at Launch....................................... 58

Figure 4.2: Build Positive Coverage by Providing Media Access to KOLs .................................... 60

Figure 4.3: Media Spotlights Can Reach Millinons in a Few Seconds .......................................... 61

Figure 4.4: Human-Interest Positioning Touches Hearts............................................................... 62

Figure 4.5: Patient Advocacy Groups are Trusted Sources of Information ................................... 64

Figure 4.6: Differentiating a Product Means Building Advocacy Group Bridges ........................... 65




Best Practices, LLC © (919) 403-0251                                                                                                                    10
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




Figure 4.7: High-Impact Public Relations Campaings Relate the Medical Condition to the
Consumer....................................................................................................................................... 66

Figure 4.8: Relate the Medical Condition to the Consumer ........................................................... 67

Figure 4.9: Employ Public Relations Tools to Help Patients Assess their Personal Risk ............. 68

Figure 4.10: Pfizer Focuses its Marketing Skills on Animal Health ............................................... 69

Figure 4.11: Engage Consumers in Disease Awareness Research.............................................. 70

Figure 4.12: Later Public Relations Drives Consumers to Branded Website ................................ 71

Figure 4:13: “BARC” as a Diagnostic Tool..................................................................................... 72

Figure 4:14: New Media Public Relations Were Integral to Slentrol’s Campaign.......................... 73

Figure 5.1: Public Relations Tools, Post-Launch........................................................................... 74

Figure 5.2: Websites with Referral Mechanisms Expand Reach................................................... 75

Figure 5.3: Public Relations Success Stories Often Inolve Partnerships ...................................... 76

Figure 5.4: Employ Public Relations Lifestyle Campgaigns to Educate and Personalize
the     Condition ........................................................................................................................... 77

Figure 5.5: Edgy Public Relations Raises Awareness for Symptomless Conditions..................... 78

Figure 5.6: Anchor Brand Positioning Public Relations in Science, Safety and Unmet
Need............................................................................................................................................... 79

Figure 5.7: A Celebirty Spokesperson can Help Personalize and Educate................................... 80

Figure 5.8: Flomax Branded Website around the One-Week Challenge ...................................... 81

Figure 5.9: Websites are an Essential Tool in Patient and Family Education ............................... 82

Figure 5.10: Motivate Men to Seek “One Week” Improvement in Quality of Life .......................... 83

Figure 5.11: Target Patient’s Family to Accelerate Treatment Pathway ....................................... 84

Figure 6.1: Later Stage Public Relations Tool Effectiveness......................................................... 86

Figure 6.2: Position Product Public Relation to Reflect Cost Benefits........................................... 88

Figure 6.3: Public Relations Leveraging: Flomax .......................................................................... 90

Figure 6.4: Build Bridges Between Product Generation to Transition Patients ............................. 92

Figure 6.5: Provide Information Support throughout the Customer Lifecycle................................ 93

Figure 6.6: Employ Tools to Seed and Grow Relationships with Patients in Chronic Care
Conditions ...................................................................................................................................... 94

Figure 6.7: Education Tools Inform and Help Patients Self-Diagnose .......................................... 95




Best Practices, LLC © (919) 403-0251                                                                                                                     11
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




Figure 6.8: Polls Educate, Inform and Engage Patients ................................................................ 96

Figur 6.9: Engage Patients on Lifestyle Fronts.............................................................................. 97

Figure 6.10: Employ Technologies to Extend Education to Patient Populations........................... 98

Figure 6.11: Public Relations Campaigns Trumpet “Nexium-Kids” Version .................................. 99

Figure 6.12: A Celebrity Spokesperson Helps to Humanize Medical Conditions........................ 100

Figure 7.1: Effective Public Relations Tools: Patent Expiration................................................... 101

Figure 7.2: Use YouTube to Create Buzz and Flu Awareness .................................................... 102

Figure 7.3: Use a Contest to Engage Amateurs and Professionals ............................................ 103

Figure 8.1: Public Relations Tools Help Educate and Inform the Market .................................... 105




Best Practices, LLC © (919) 403-0251                                                                                              12
Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands




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Best Practices, LLC © (919) 403-0251                                                                                13

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Using Public Relations to Launch, Grow and Extend Your Brands Report Summary

  • 1. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands Using Public Relations to Launch, Grow and Extend Your Brands PROJECT BACKGROUND While Public Relations has long been used as a marketing tool by the pharmaceutical and biotechnology industries, its Benchmarking Report ability to reach consumers has never been greater. However, at-a-Glance field research suggests few companies utilize the full potential of Public Relations campaigns throughout the Featured Study Participants entire product lifecycle – from preparing and launching to • Abbott Laboratories growing and extending a brand. • AstraZeneca • AtheroGenics New technologies and market changes have greatly • Boehringer Ingelheim expanded the reach and potential of cost-efficient Public • Boiron Relations through websites, online social networks, blogs • Cubist Pharmaceuticals and traditional media sources. These mediums have joined • Emcure the traditional press release as effective and low-cost • Farmasa Schwabe methods that help drive sales. • Gebauer Company • Genentech This research identifies which Public Relations activities • Jazz Pharmaceuticals most effectively educate and inform consumers at different • Johnson & Johnson points in a product's lifecycle. The report also delivers • Merck Serono insights into the most effective Public Relations channels, • Novartis tactics and calls-to-action for reaching consumers of • Novo Nordisk pharmaceutical products. Four case studies of successful • Pfizer products are included in this report to highlight Public • Solvay Relations tactics at different lifecycle stages: Slentrol • Wyeth (product launch), Flomax (brand-building), Nexium (product Best Practices, LLC © (919) 403-0251 1
  • 2. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands maturity) and Fluvirin (patent expiration). Industry Analysis 18 benchmark companies representing This report’s objectives include: the biopharmaceutical industry participated in this study. • Assessing Public Relations strategies and tactics that are most effective at different lifecycle Information Types stages • 57 Information Graphics • Identifying Public Relations tools and calls-to- • 29 Data Graphics • 600+ Metrics action that are most effective • 35 Best Practices • 28 Executive Narratives • Providing case analogs that reveal effective practices Report Length • Revealing innovative practices • 108 pages Topics covered in this study include: • Public Relations strategies and tactics that are most effective at different lifecycle stages • The most effective Public Relations tools and calls-to-action • Case studies that reveal valuable Public Relations practices • Successful website resources for consumers • Ideal budget ratios and performance measurements • Lessons learned and best practices STUDY METHODOLOGY This report comprises quantitative data and insights drawn from surveyed executives at 18 top pharmaceutical companies. This research also features deep-dive interviews with selected executives at seven of these companies. The report profiles executives, directors and managers in Marketing and Public Relations and uncovers their recommendations for better aligning Public Relations activities and tactics with the different stages of a product’s lifecycle. In addition, this report provides leaders with insights into performance measurements for Public Relations campaigns and those web-based resources that best engage patients. Best Practices, LLC © (919) 403-0251 2
  • 3. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands REPORT STRUCTURE AND ORGANIZATION The project findings are organized into an executive summary, six topical chapters and an appendix. Following is a description of each section: • Executive summary: Explains the survey methodology, identifies participating companies and reports key findings. • Topical chapters: Features an overview of Optimal Use of Public Relations Tools and explores Public Relations approaches during each of the major lifecycle stages: Pre- Launch, Launch, Brand-Building, Late-Life Management and Patent Expiration Management. Four case studies are highlighted. • Appendix: Underlines Public Relations lessons learned and sets out general good practices. SAMPLE FINDINGS Among the findings that emerged from this research are the following: • Public Relations Strategies, Tools and Tactics Can Be Employed Across the Product Lifecycle: Field research identified effective uses of Public Relations throughout the product lifecycle. Moreover, more Public Relations forms proved effective than any one brand has sought to employ. This suggests that Public Relations tools may be underutilized across all lifecycle stages. • Public Relations Is a Cornerstone of Market-Entry Launch and Brand-Building: Field research revealed a “holy trinity” for Public Relations specialists. The three aspects of this operational strategy are human-interest positioning, lifestyle positioning and family relevance positioning. Public Relations campaigns that touch these groups tend to engage consumers and win media attention. • Public Relations Strategies, Tools and Tactics Can Profitably Extend the Brand During Its Later Life: Certain Public Relations tactics prove very useful for targeting new sub-populations that are under-served or newly served by the brand. Social networking communities are effective ways for patients, family members and friends to share information and resources and offer support about a common medical condition. Best Practices, LLC © (919) 403-0251 3
  • 4. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands • Public Relations Can Help Build a Bridge from First-Generation to Next-Generation Blockbuster: Building Bridges: Integrated Public Relations and communication strategies helped AstraZeneca and Eli Lilly build sturdy bridges from Prilosec to Nexium and from Prozac to Cymbalta. This “bridge building” requires good planning and, ideally, should commence at the back end of the first-generation product’s lifecycle. Timing of the Bridge Building: Field findings revealed that successor products generally should commence Public Relations two years prior to the new product’s global launch. Some participants recommended three years lead time. • New Technologies Create New Public Relations Opportunities: Social networking sites – such as Facebook, MySpace or disease-specific sites, like DepNet.com for depression sufferers – create links between brands and patients. Savvy communication experts are engaging these social networks throughout all stages of a brand’s lifecycle. DATA SECTION EXCERPTS PR Effectiveness, Timing and Budget (an Excerpt) Public Relations tools benefit all phases of the product lifecycle. However, research participants identify the pre-launch, launch and growth phases as the highest-impact lifecycle stages for Public Relations influence and effectiveness. “Now along the span of the As one interviewed director said, “The first few years is where it (product) life, you are evaluating [Public Relations] matters because that’s when you’re creating your how many competitors there are, what is the market share, market share and that’s when you’re dominating. The more you what is their share of voice and wait, the less it’s effective because decisions have made habits; what share of voice you want. If you want to become the leader doctors have decided already what they’re prescribing.” of share of voice and you want to steal market share, then you Still, nearly 50 percent of companies reported Public Relations have to speak louder than effectiveness during product maturity, and 16 percent reported them.” -Interviewed Executive Director, Public Relations tools to be effective during product decline. Communications Best Practices, LLC © (919) 403-0251 4
  • 5. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands Pre-Launch, Launch & Growth Phases Benefit Greatly from PR Rate how effective your public relation campaigns have been during the following stages of the product’s lifecycle: Percentage of N respondents for Each Total Benchmark Class Stage Average Effectiveness for Each Stage Highly Highly Highly Highly Ineffective Effective Ineffective Effective Top 2 Boxes Public Relations Effectiveness N 1 2 3 4 5 1 2 3 4 5 Pre-Launch 14 0% 0% 7% 43% 50% 93% 4.428571 Launch 15 0% 0% 7% 20% 73% 93% 4.666667 Growth ( 1 - 5 years post-launch 16 0% 0% 0% 56% 44% 100% ) 4.4375 Mature ( 5 years post - launch to 15 0% 7% 47% 20% 27% 47% Patent Expiration ) 3.666667 Decline ( Post - Patent Expiration 16% 13 23% 38% 23% 8% 8% ) 2.384615 Figure 2.21: Pre-Launch, Launch & Growth Phases Benefit Greatly From Public Relations Public Relations spending is a “highly leveraged” marketing investment, meaning that a relatively small investment can provide high returns. Consequently, Public Relations investment ratios – as a percent of total marketing –consistently comprise 20-25 percent of budget until a product nears patent expiration, when most marketing expenditures are cut. One interviewed executive offered the opinion that “Big pharma -- with a lot of foresight --will fund their brands until the patent expires. Some other pharma will have to switch funds from one brand to a new brand and have to deal with less money and will only tend to fund the first year or the first two years, and that’s a bit of a mistake.” Best Practices, LLC © (919) 403-0251 5
  • 6. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands General Good Practices (an Excerpt) Public Relations tactics and tools are broad-reaching. Over time, Public Relations forms have proliferated – all targeted at reaching core influence groups like physicians, patients and media. Public Relations uses information-based calls-to-action to send the target audiences to resources of education, information or expertise. PR Tools Help Educate & Inform The Market Growth / Brand Transition / Pre-Launch/ Launch Maturity Decline Building Development Press Release CALLS TO ACTION Physicians Call Advocacy Audio PR Centers Groups TARGETS You Patients Tube Advertorial Ask Video PR Media Corp or Your MD Brand Social Networks Info Forum Blogs Website Figure 8.1: Public Relations Tools Help Educate and Inform the Market Many strategies and tactics have relevance for products across all lifecycle phases, but these practices are most effective for brands at launch and growth phases. However, the tactics must fit the individual product. Integrated communication strategies are essential in coordinating campaigns directed at different target groups. • Family-Related Public Relations Can Help With Key Sup-Populations: Family-oriented Public Relations can be a useful approach in engaging key sub- populations by age, gender and ethnicity. Best Practices, LLC © (919) 403-0251 6
  • 7. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands • Seed Public Relations with Insights About Personal Risk: Employ Public Relations tools to help patients assess their personal risk for a specific medical condition. • Include Diagnostic Tools on Product’s Web Site: Seed websites with useful online diagnostic tools to educate and expedite change. • Seed Web Site with Consumer Incentives: Populate brand websites with incentives (coupons, samples, co-pay assistance, contests, etc.) to engage consumers. • Use Patient Stories to Attract Different Groups: Use patient stories in a product’s Public Relations that cut across different patient groups and target high growth sub-populations. ABOUT BENCHMARKINGREPORTS.COM BenchmarkingReports.com is a service of Best Practices, LLC, world-leader in benchmarking research and analysis. BenchmarkingReports.com provides vital insights and data from our primary research at a fraction of original project cost. Best Practices, LLC has conducted pioneering benchmarking research for top companies since 1991, providing clients with "Access and Intelligence for Achieving World-Class Excellence." To learn how we can help you find solutions to your current business issues, visit our site at www.best-in-class.com. Best Practices, LLC © (919) 403-0251 7
  • 8. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands TABLE OF CONTENTS Executive Summary ....................................................................................................................... 6 INTRODUCTION.............................................................................................................................. 6 RESEARCH APPROACH ................................................................................................................ 8 PARTICPANT DEMOGRAPHICS.................................................................................................... 8 DEFINITIONS AND ABBREVIATIONS.......................................................................................... 10 REPORT STRUCTURE AND ORGANIZATION............................................................................ 10 KEY FINDINGS.............................................................................................................................. 10 Using Public Relations Tools for Optimal Advantage.............................................................. 14 PUBLIC RELATIONS CALLS-TO-ACTION ................................................................................... 22 RESOURCES AND SUPPORT SERVICES .................................................................................. 27 EFFECTIVENESS, TIMING AND BUDGET .................................................................................. 33 Pre-Launch ................................................................................................................................... 40 Launch .......................................................................................................................................... 58 CASE STUDY SPOTLIGHT: SLENTROL...................................................................................... 68 Brand-Building ............................................................................................................................. 74 CASE STUDY SPOTLIGHT: FLOMAX.......................................................................................... 78 Late-Life Management ................................................................................................................. 86 CASE STUDY SPOTLIGHT: NEXIUM........................................................................................... 91 Patent Expiration Management ................................................................................................ 101 CASE STUDY SPOTLIGHT: FLUVIRIN ...................................................................................... 102 Lessons Learned........................................................................................................................ 105 GENERAL GOOD PRACTICES .................................................................................................. 105 ENGAGE, INFORM AND EDUCATE........................................................................................... 106 TAILOR LATE-STAGE TACTICS TO REACH SELECT SUB-POPULATION ............................ 107 BRIDGE THE GAP BETWEEN PRODUCT GENERATIONS ..................................................... 107 Best Practices, LLC © (919) 403-0251 8
  • 9. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands TABLES AND FIGURES Table 1.1: Participating Companies ................................................................................................. 8 Figure 1.1: Participant Job Titles ..................................................................................................... 9 Figure 1.2: Benchmark Partners’ Experience .................................................................................. 9 Figure 2.1: Apply Public Relations Tools and Tactics Throughout the Lifecycle ........................... 14 Figure 2.2: Public Relations Tool Effectiveness Changes Over the Brand Lifecyle ...................... 15 Figure 2.3: Media Interviews Get Company’s Message Out Best ................................................. 16 Figure 2.4: Blogs and Social Networks Get Message Out in New Ways ...................................... 17 Figure 2.5: Patient Groups, Human-Interest Key to Informing Patients and Family...................... 18 Figure 2.6: Public Relations Positioning Tactics Offer Brand Teams Many Options..................... 19 Figure 2.7: Human-Interest Stories Resonate with Patients, Media.............................................. 20 Figure 2.8: Tactical Elements Appealing to Consumers Rated Best............................................. 21 Figure 2.9: Ask Physician About Condition Rates Highest ............................................................ 22 Figure 2.10: Public Relations Calls-To-Action Direct Consumers to Experts and Expertise......... 23 Figure 2.11: Inform and Inspire Consumers to Take Action on Their Own Behalf ........................ 24 Figure 2.12: Web-Based Calls-To-Action Direct Patients to Resources ....................................... 25 Figure 2.13: Medical Condition Websites Are Most Highly Rated ................................................. 26 Figure 2.14: Brand Websites Have More Options to Engage Consumers .................................... 27 Figure 2.15: Consumers Relate Well to Patient Stories ................................................................ 28 Figure 2.16: Best Web-Based Resouces Inform and Engage Patients......................................... 29 Figure 2.17:Testimonials Offer Valuable Hope and Tips for Patients............................................ 30 Figure 2.18: Patient Advocacy Groups Are Key Partners.............................................................. 31 Figure 2.19: Key Public Relations Support Resources Help Inform Patients ................................ 32 Figure 2.20: Trusted Information Sources Are Best Support Service............................................ 33 Figure 2.21: Pre-Launch, Launch and Growth Phases Benefit Greatly From Public Relations ........................................................................................................................................ 34 Figure 2.22: Public Relations Budgets as a Percentage of Annual Marketing Spend................... 35 Best Practices, LLC © (919) 403-0251 9
  • 10. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands Figure 2.23: Measuring Public Relations Is a Double-Edged Sword............................................. 36 Figure 2.24: Public Relations Performance Metrics Are Critical but Imprecise ............................. 37 Figure 2.25: Begin Public Relations Early to Bridge From One Brand to Successor .................... 38 Figure 3.1: Public Relations Can Creat Buzz for New Treatment Paradigms ............................... 39 Figure 3.2: Formulas for Bringing Non-Intuitive Mechanism-of-Action Medicines to Market......... 41 Figure 3.3: Public Relations Tool Effectiveness at Pre-Launch..................................................... 42 Figure 3.4: Employ Public Relations to Reach Consumers Through Patient Advocacy Groups ........................................................................................................................................... 43 Figure 3.5: Early Public Relations Guides Consumers to Trusted Third-Party Informational Resources ................................................................................................................ 44 Figure 3.6: Introduce New Medical Ideas through Third-Party Expertise: Cymbalta..................... 45 Figure 3.7: Inform Consumers Through PR, Educational Messages and Personal Stories: Cymbalta ........................................................................................................................................ 46 Figure 3.8: Shaping the Market for Successful Entry of New Products: Rituxin............................ 47 Figure 3.9: Early Advisory Board Harvests Insights and Seeds New Ideas .................................. 48 Figure 3.10: Dare to Kick-Start Debate Before Full Clinical Data are Available ............................ 50 Figure 3.11: Pre-Launch Scientific Discussion – But Don’t Promt Off-Label................................. 51 Figure 3.12: Pre-Launch Scientific Communications..................................................................... 52 Figure 3.13: B-Cell Dinners: Use Peer-to-Peer Discussions to Extend Science ........................... 53 Figure 3.14: Seminars and Congresses Extend Message to Broader Audience .......................... 54 Figure 3.15: Carefully Manage Expectations Pre-Launch ............................................................. 55 Figure 3.16: Carefully Manage Expectations Post-Launch............................................................ 56 Figure 3.17: Blueprint for Market-Entry Success ........................................................................... 57 Figure 4.1: Using Experts, Media and Ed Events to Educate at Launch....................................... 58 Figure 4.2: Build Positive Coverage by Providing Media Access to KOLs .................................... 60 Figure 4.3: Media Spotlights Can Reach Millinons in a Few Seconds .......................................... 61 Figure 4.4: Human-Interest Positioning Touches Hearts............................................................... 62 Figure 4.5: Patient Advocacy Groups are Trusted Sources of Information ................................... 64 Figure 4.6: Differentiating a Product Means Building Advocacy Group Bridges ........................... 65 Best Practices, LLC © (919) 403-0251 10
  • 11. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands Figure 4.7: High-Impact Public Relations Campaings Relate the Medical Condition to the Consumer....................................................................................................................................... 66 Figure 4.8: Relate the Medical Condition to the Consumer ........................................................... 67 Figure 4.9: Employ Public Relations Tools to Help Patients Assess their Personal Risk ............. 68 Figure 4.10: Pfizer Focuses its Marketing Skills on Animal Health ............................................... 69 Figure 4.11: Engage Consumers in Disease Awareness Research.............................................. 70 Figure 4.12: Later Public Relations Drives Consumers to Branded Website ................................ 71 Figure 4:13: “BARC” as a Diagnostic Tool..................................................................................... 72 Figure 4:14: New Media Public Relations Were Integral to Slentrol’s Campaign.......................... 73 Figure 5.1: Public Relations Tools, Post-Launch........................................................................... 74 Figure 5.2: Websites with Referral Mechanisms Expand Reach................................................... 75 Figure 5.3: Public Relations Success Stories Often Inolve Partnerships ...................................... 76 Figure 5.4: Employ Public Relations Lifestyle Campgaigns to Educate and Personalize the Condition ........................................................................................................................... 77 Figure 5.5: Edgy Public Relations Raises Awareness for Symptomless Conditions..................... 78 Figure 5.6: Anchor Brand Positioning Public Relations in Science, Safety and Unmet Need............................................................................................................................................... 79 Figure 5.7: A Celebirty Spokesperson can Help Personalize and Educate................................... 80 Figure 5.8: Flomax Branded Website around the One-Week Challenge ...................................... 81 Figure 5.9: Websites are an Essential Tool in Patient and Family Education ............................... 82 Figure 5.10: Motivate Men to Seek “One Week” Improvement in Quality of Life .......................... 83 Figure 5.11: Target Patient’s Family to Accelerate Treatment Pathway ....................................... 84 Figure 6.1: Later Stage Public Relations Tool Effectiveness......................................................... 86 Figure 6.2: Position Product Public Relation to Reflect Cost Benefits........................................... 88 Figure 6.3: Public Relations Leveraging: Flomax .......................................................................... 90 Figure 6.4: Build Bridges Between Product Generation to Transition Patients ............................. 92 Figure 6.5: Provide Information Support throughout the Customer Lifecycle................................ 93 Figure 6.6: Employ Tools to Seed and Grow Relationships with Patients in Chronic Care Conditions ...................................................................................................................................... 94 Figure 6.7: Education Tools Inform and Help Patients Self-Diagnose .......................................... 95 Best Practices, LLC © (919) 403-0251 11
  • 12. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands Figure 6.8: Polls Educate, Inform and Engage Patients ................................................................ 96 Figur 6.9: Engage Patients on Lifestyle Fronts.............................................................................. 97 Figure 6.10: Employ Technologies to Extend Education to Patient Populations........................... 98 Figure 6.11: Public Relations Campaigns Trumpet “Nexium-Kids” Version .................................. 99 Figure 6.12: A Celebrity Spokesperson Helps to Humanize Medical Conditions........................ 100 Figure 7.1: Effective Public Relations Tools: Patent Expiration................................................... 101 Figure 7.2: Use YouTube to Create Buzz and Flu Awareness .................................................... 102 Figure 7.3: Use a Contest to Engage Amateurs and Professionals ............................................ 103 Figure 8.1: Public Relations Tools Help Educate and Inform the Market .................................... 105 Best Practices, LLC © (919) 403-0251 12
  • 13. Report Summary: Using Public Relations to Launch, Grow and Extend Your Brands ORDER FORM I’d like to order the following Best Practice Benchmarking Report.® ID PUBLICATION TITLE QUANTITY PRICE SUBTOTAL SM-181 Using Public Relations to Launch, Grow and Extend Your Brands Ordering 3 or more reports Deduct 10% Options Shipping and Handling: Add $26 ($48 international) per report ONLINE TOTAL benchmarkingreports.com PHONE SHIP TO: (919) 403-0251 Name Title FAX (919) 403-0144 Company EMAIL Street Address bestpractices@best-in- class.com City/State/Country Zip MAIL Phone Fax Best Practices, LLC 6350 Quadrangle Drive Email Suite 200 Chapel Hill, NC 27517 PAYMENT OPTIONS: Check enclosed payable to “Best Practices, LLC” Visa MasterCard American Express Card Number Exp. Date Authorized Signature Best Practices, LLC © (919) 403-0251 13