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GET THE LEAD OUT! Dorothy Merritt, MD
Lead –Who Is Affected The Most Blood-brain barrier is not complete until 6 months of age so lead can be absorbed by CNS of fetus and  young child   ( lead crosses placenta). Absorption of lead is estimated to be as much as  FIVE TO TEN TIMES GREATER  in infants and young children than in adults. Needleman H. Ann Rev Med 2004;55:209-222
Lead: Where does it come from? ,[object Object],[object Object],[object Object],[object Object]
Lead: Where does it come from? Billions of tons of lead has been unleased into the environment  the last 100 years due to paint and gasoline additives that have now been banned in the US and Europe ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lead in Wine ,[object Object]
Lead glaze used on plate imported from Portugal and sold at American Home Furnishings
Fatal Case of Lead Poisoning from Injestion of Jewelry ,[object Object],[object Object],[object Object],[object Object]
Occupations at risk for lead toxicity ,[object Object],[object Object],[object Object],[object Object],[object Object]
Total = 12,712 Section   44 of The Construction Chart Book, Fourth Edition, December 2007 - Distribution of workers with BLLs greater than or equal to 25  µg/dL,  by industry, 2003-2004
Number of workers with BLLs greater than or equal to 25 or 40  µg/dL ,  by detailed construction sector, 2003-2004 1,051 406 412 92 70 41 41 39 14 Section 44 of The Construction Chart Book, Fourth Edition, December 2007
NOEL  N o  O bservable  E ffect  L evel  ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Circulation  2006;114;1347-1349 Tim S. Nawrot and Jan A. Staessen NHANES DATA ,[object Object],Editorial in  Circulation 2006  with Latest NHANES Study On Lead And Vascular Disease
Lead Toxicity-Early Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lead Toxicity Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lead-Related Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
Lead-Related Symptoms ,[object Object],[object Object],[object Object],[object Object],[object Object]
Lead Toxicity in the US  2010 Blood lead levels:  NHANES STUDIES (Reflects 30-60 day exposure) Bone lead levels :  NIH STUDIES (Reflects LIFETIME exposure) Measured by urine “challenge” test
NIH Study Lead in Bones Adult Implictions ,[object Object],[object Object]
Populations at risk for lead toxicity from increased bone turnover ,[object Object],[object Object],[object Object],[object Object],[object Object]
Cardiovascular Disease ,[object Object],[object Object],[object Object],[object Object],[object Object],[object Object],[object Object]
SO WHAT DO YOU DO ? ,[object Object],[object Object],[object Object],[object Object],[object Object]
What is “Chelation” ,[object Object],[object Object],[object Object],[object Object]
Check list for heavy metal symptoms used in our clinic
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CHELATION PRESENTATION

  • 1. GET THE LEAD OUT! Dorothy Merritt, MD
  • 2. Lead –Who Is Affected The Most Blood-brain barrier is not complete until 6 months of age so lead can be absorbed by CNS of fetus and young child ( lead crosses placenta). Absorption of lead is estimated to be as much as FIVE TO TEN TIMES GREATER in infants and young children than in adults. Needleman H. Ann Rev Med 2004;55:209-222
  • 3.
  • 4.
  • 5.
  • 6. Lead glaze used on plate imported from Portugal and sold at American Home Furnishings
  • 7.
  • 8.
  • 9. Total = 12,712 Section 44 of The Construction Chart Book, Fourth Edition, December 2007 - Distribution of workers with BLLs greater than or equal to 25 µg/dL, by industry, 2003-2004
  • 10. Number of workers with BLLs greater than or equal to 25 or 40 µg/dL , by detailed construction sector, 2003-2004 1,051 406 412 92 70 41 41 39 14 Section 44 of The Construction Chart Book, Fourth Edition, December 2007
  • 11.
  • 12.
  • 13.
  • 14.
  • 15.
  • 16.
  • 17. Lead Toxicity in the US 2010 Blood lead levels: NHANES STUDIES (Reflects 30-60 day exposure) Bone lead levels : NIH STUDIES (Reflects LIFETIME exposure) Measured by urine “challenge” test
  • 18.
  • 19.
  • 20.
  • 21.
  • 22.
  • 23. Check list for heavy metal symptoms used in our clinic
  • 24.
  • 25.