LICHEN PLANUSLICHEN PLANUS
BY
DR.MAHESHDR.MAHESH
MATHURMATHUR,,MD,DVD,DCP(UK)MD,DVD,DCP(UK)
LICHEN PLANUS
DIFINETION
CHRINIC INFLAMMATORY DISEASE OF UNKNOW
ETIOLOGY CHARECTRISED BY ------
SHINY VIOLACEOUS ITCHY FLA...
INCIDENCE
 WORLD WIDE – MUCH MORE IN ASIAN
COUNTRIES
 1 TO 2 % OF ALL NEW CASES IN
DERMATOLOGY CLINIC
 SKIN LESION SUBS...
PATHOGENESIS
 AUTOIMMUNE –
INFILTRATION OF CD 4+ / CD 8+CELLS &
INCREAS IN Langerhan’S CELLS NUMBER IN
SKIN LESIONS
 FAM...
CLINICAL TYPES
 HYPERTROPHICUS
 FOLLICULAR
 ACTINICUS
 PIGMENTOSUS
 ANULAR
 LINEAR
 GUTTATE
 NAIL- 15%
 MUCOSAL- ...
TYPICAL LICHEN PLANUS
TYPICAL LICHEN PLANUS
 SHINY,
 VIOLACEOUS
 PAPULAR
 LESIONS
KOBNER’S PHENOMENON
WICHAM’S STRAIE
LICHEN PLANUS
HYPERTROPHICUS
LICHEN PLANUS
HYPERTROPHICUS
LICHEN PLANUS -
BULLOSUS
BULLOUS LICHEN PLANUS
LICHEN PLANUS
ANNULAR LESION AT SHAFT OF
PENIS
LICHEN PLANUS
ACTINICUS
LICHEN PLANUS TROPICUS
LICHEN PLANOPILARIS
CICATRICAL ALOPECIA
LICHEN PLANS AT PALM
LICHEN PLANUS AT FOOT
LICHEN PLANUS-ORAL LESION
ORAL LICHEN PLANUS
LICHEN PLANUS AT
TONGUE
LICHEN PLANUS -TONGUE
EROSIVE LICHEN PLANUS
PERI ANAL LICHEN PLANUS
LICHEN PLANUS – PERIANAL
REGION
NAIL CHANGES IN LICHEN
PLANUS
LICHEN PLANUS- NAILS
HISTOPATHOLOGY
 HYPERKERATOSIS
 HYPERGRANULOSIS
 ACANTHOSIS
 LIQUFYING DEGENERATION
OF BASAL CELL LAYER
 EOSINOPHILIC...
HISTOPATHOLOGY HIGH
MAGNIFICAITON
LICHEN PLANOPILARIS
IMMUNOFLOURACENCE
 IgG & C3
 DEPOSITION
AT DERMOEPIDERMAL
JUNCTION
IMMUNOFLOURACENCE
 CYTOID BODIES
 IGM STAINING
DRUGS CASUUSING
LICHENOID REACTION
 ANTIMALARIALS
 THIAZID DIURATICS
 ISONIAZID
 CHLORPROPAMID
 B-BLOCKERS
 KETOCONA...
LICHENOID DRUG RASH
TREATMENT & PROGNOSIS
 STEROIDS-TOPICAL & SYSTAMIC
 PUVA
 CYCLOSPOIN
 AZOTHIOPRIN
Nächste SlideShare
Wird geladen in …5
×

Lichen planus

1.273 Aufrufe

Veröffentlicht am

Lichen planus

Veröffentlicht in: Gesundheit & Medizin
1 Kommentar
0 Gefällt mir
Statistik
Notizen
  • Gehören Sie zu den Ersten, denen das gefällt!

Keine Downloads
Aufrufe
Aufrufe insgesamt
1.273
Auf SlideShare
0
Aus Einbettungen
0
Anzahl an Einbettungen
16
Aktionen
Geteilt
0
Downloads
4
Kommentare
1
Gefällt mir
0
Einbettungen 0
Keine Einbettungen

Keine Notizen für die Folie

Lichen planus

  1. 1. LICHEN PLANUSLICHEN PLANUS BY DR.MAHESHDR.MAHESH MATHURMATHUR,,MD,DVD,DCP(UK)MD,DVD,DCP(UK)
  2. 2. LICHEN PLANUS DIFINETION CHRINIC INFLAMMATORY DISEASE OF UNKNOW ETIOLOGY CHARECTRISED BY ------ SHINY VIOLACEOUS ITCHY FLAT TOPPED PAPULAR LESIONS MORPHOLOGICALLY & HISTOLOGICALLY CHARECTERISED BY -------- LIQUIFIED DEGENRATION OF BASAL CELL LAYER AND BAND LIKE LINEAR CELLULAR INFILTRATION IN DERMIS
  3. 3. INCIDENCE  WORLD WIDE – MUCH MORE IN ASIAN COUNTRIES  1 TO 2 % OF ALL NEW CASES IN DERMATOLOGY CLINIC  SKIN LESION SUBSIDES IN 50 % OF CASES IN 9 MONTHS AND 100% BY 18 MONTHS  MUCOUS MEMBREANS INVOLVE IN 30 OT 70 % CASES  NAIL INVOLMENT IN 10% OF CASES
  4. 4. PATHOGENESIS  AUTOIMMUNE – INFILTRATION OF CD 4+ / CD 8+CELLS & INCREAS IN Langerhan’S CELLS NUMBER IN SKIN LESIONS  FAMILIAL- HLA B7 -
  5. 5. CLINICAL TYPES  HYPERTROPHICUS  FOLLICULAR  ACTINICUS  PIGMENTOSUS  ANULAR  LINEAR  GUTTATE  NAIL- 15%  MUCOSAL- 40 TO 60% ORAL PERIANAL ESOPHAGIAL GENITAL
  6. 6. TYPICAL LICHEN PLANUS
  7. 7. TYPICAL LICHEN PLANUS  SHINY,  VIOLACEOUS  PAPULAR  LESIONS
  8. 8. KOBNER’S PHENOMENON
  9. 9. WICHAM’S STRAIE
  10. 10. LICHEN PLANUS HYPERTROPHICUS
  11. 11. LICHEN PLANUS HYPERTROPHICUS
  12. 12. LICHEN PLANUS - BULLOSUS
  13. 13. BULLOUS LICHEN PLANUS
  14. 14. LICHEN PLANUS
  15. 15. ANNULAR LESION AT SHAFT OF PENIS
  16. 16. LICHEN PLANUS ACTINICUS
  17. 17. LICHEN PLANUS TROPICUS
  18. 18. LICHEN PLANOPILARIS
  19. 19. CICATRICAL ALOPECIA
  20. 20. LICHEN PLANS AT PALM
  21. 21. LICHEN PLANUS AT FOOT
  22. 22. LICHEN PLANUS-ORAL LESION
  23. 23. ORAL LICHEN PLANUS
  24. 24. LICHEN PLANUS AT TONGUE
  25. 25. LICHEN PLANUS -TONGUE
  26. 26. EROSIVE LICHEN PLANUS
  27. 27. PERI ANAL LICHEN PLANUS
  28. 28. LICHEN PLANUS – PERIANAL REGION
  29. 29. NAIL CHANGES IN LICHEN PLANUS
  30. 30. LICHEN PLANUS- NAILS
  31. 31. HISTOPATHOLOGY  HYPERKERATOSIS  HYPERGRANULOSIS  ACANTHOSIS  LIQUFYING DEGENERATION OF BASAL CELL LAYER  EOSINOPHILIC CYTOID BODIES
  32. 32. HISTOPATHOLOGY HIGH MAGNIFICAITON
  33. 33. LICHEN PLANOPILARIS
  34. 34. IMMUNOFLOURACENCE  IgG & C3  DEPOSITION AT DERMOEPIDERMAL JUNCTION
  35. 35. IMMUNOFLOURACENCE  CYTOID BODIES  IGM STAINING
  36. 36. DRUGS CASUUSING LICHENOID REACTION  ANTIMALARIALS  THIAZID DIURATICS  ISONIAZID  CHLORPROPAMID  B-BLOCKERS  KETOCONAZOLE  NSADS  ACE INHIBITORS  TETRACYCLINE  COLOURING AGENTS
  37. 37. LICHENOID DRUG RASH
  38. 38. TREATMENT & PROGNOSIS  STEROIDS-TOPICAL & SYSTAMIC  PUVA  CYCLOSPOIN  AZOTHIOPRIN

×