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REFLEX
CONTENTS:
DEFINITION
 REFLEX ARC
 TYPES/CLASSIFICATION OF
REFLEXES
 STRETCH REFLEX
 MUSCLE SPINDLE
 PROPERTIES OF REFLEXES


24-Feb-14

Dr. Ashok Solanki

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Dr. Ashok Solanki

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Nerve pathways
Ascending Tracts
Tract
Signal function

Dorsal columns

Vibration, tactile sensation, conscious
proprioception

Spinocerebeller
Spinothalamic (lateral and

Proprioception

anterior)

Spinoreticular
Spinomesencephalic
Spino-cervico-thalamic
Spinohypothalamic

Pain, temperature, itch (lateral), crude
touch (anterior)
Pain
Pain
Pain (touch?)
Pain
Structure of spinal cord

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Dr. Ashok Solanki

5
Spinal cord





Fetal 3rd month: ends at
coccyx
Birth: ends at L3
Adult position at approx L1-2
during childhood
End: conus medullaris






This tapers into filum terminale
of connective tissue, tethered
to coccyx

Spinal cord segments are
superior to where their
corresponding spinal nerves
emerge through intervetebral
foramina (see also fig 17.5, p
288)
Denticulate ligaments: lateral
shelves of pia mater anchoring
to dura (meninges: more later)
http://www.apparelyzed.com/spinalcord.html
Spinal nerves continued








Divided based on vertebral locations
8 cervical
12 thoracic
5 lumbar
5 sacral
1 coccygeal
Cauda equina (“horse’s tail”): collection of nerve
roots at inferior end of vertebral canal
Classified as
According to centre IN THE SPINAL CORDseg, inter, supra.
According to functionflexor, extensor, postural R.
Clinicallysupreficial, deep, visceral
No. of synapse involved.
Mono and polysynaptic
According to origin–
spinal cord, brain stem, cortical etc.
Conditional and unconditional – since birth


Rapid, stereotyped, invountary response to a sensory stimuli
Dr. Ashok .
consciouslly or unconsciousllySolanki

24-Feb-14

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CLASSIFICATION
CONDITIONED (ACQUIRED)/
UNCONDITIONED(SINCE BIRTH)
 CEREBELLER, CORTICAL, MIDBRAIN,
SPINAL
 SOMATIC:FLEXOR , EXTENSOR
VISCERAL: AUTONOMIC
 MONOSYNAPTIC , POLYSYNAPTIC
 SUPERFICIAL, DEEP, VISCERAL,
PATHOLOGICAL
 SEGMENTAL, INTERSEGMENTAL,
SUPRASEGMENTAL


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Dr. Ashok Solanki
Functions or reflex action
Maintain the homeostasis- b.p regulation,
heart rate, digestive , autonomic reflexes
 Automatic actions
 Balance and posture
 Reflex maintining the movements -eyes


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REFLEX ARC
ANATOMICAL NERVOUS PATHWAY OF
REFLEX IS CALLED REFLEX ARC.
RECEPTOR
SENSORY / AFFERENT NERVE
CENTER
EFFERENT / MOTOR NERVE
EFFECTOR ORGAN


* BELL-MAGENDIE LAW: DORSAL ROOTS ARE
SENSORY & VENTRAL ROOTS ARE MOTOR.
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Dr. Ashok Solanki

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SUPERFICIAL REFLEXES
CORNEAL AND CONJUNCTIVAL
REFLEX
 PHARYNGEAL REFLEX
 PALATAL REFLEX
 ABDOMINAL RELEX
 PLANTAR REFLEX: Scratch over the
outer edge of sole cause plantar flexion
and adduction of all toes and dorsiflexion
and inversion of foot.( L5,S1)
 ANAL REFLEX


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DEEP REFLEXES
JAW JERK: 5TH CRANIAL NV NUCLEI
 BICEPS JERK: C5,6
 TRICEPS JERK: C6,7
 SUPINATOR JERK: C5,6
 KNEE JERK: L2,3,4
 ANKLE JERK: S1,2


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Reflex Arc
Specific nerve impulse pathway
 5 components of reflex arc


receptor
 sensory neuron
 integrating center
 motor neuron
 effector


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PROPERTIES











ONE WAY CONDUCTION
SUMMATION: SPATIAL, TEMPORAL
OCCLUSION
SUBLIMINAL FRINGE
RECRUITMENT
AFTERDISCHARGE
REBOUND PHENOMENON
FATIGUE

RECIPROCAL INNERVATION AND
RECIPROCAL INHIBITION

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Flexor (withdrawal) Reflex





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Dr. Ashok Solanki

Step on tack (pain fibers send
signal to spinal cord
Interneurons branch to different
spinal cord segments
Motor fibers in several
segments are activated
More than one muscle group
activated to lift foot off of tack

18
Crossed Extensor Reflex







24-Feb-14

Dr. Ashok Solanki

Lifting left foot requires
extension of right leg to
maintain one’s balance
Pain signals cross to opposite
spinal cord
Contralateral extensor muscles
are stimulated by interneurons
to hold up the body weight
Reciprocal innervation - when
extensors contract flexors
relax, etc

19
Clinical Considerations
Checking a patient’s reflexes may help
to detect disorders/injury
 Plantar flexion reflex -- stroke the lateral
margin of the sole


normal response is curling under the toes
 abnormal response or response of children
under 18 months is called Babinski sign
(upward fanning of toes due to incomplete
myelination in child)


24-Feb-14

Dr. Ashok Solanki

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Inverse stretch reflex
Golgi tendon organ- 2 to 15 in each
muscle.
 Responds to tension and not the length
 The Golgi tendon reflex is a protective
reflex
 rise in tension is sensed by the Golgi
tendon a which stimulates the Ib stimulates the I-b afferents
 stimulate the inhibitory interneurons
 inhibit the α-motoneuron discharge to


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INVERSE STRETCH REFLEX/
AUTOGENIC INHIBITION


WHEN A MUSCLE IS STRETCHED, IT
CONTRACTS BUT IF THE STRETCH IS
MAINTAINED (CONTINUED), THE
MUSCLE RELAXES.

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Dr. Ashok Solanki

22
UMN lesions

LMN lesions

•weakness, paralysis

•weakness, paralysis

•spasticity

•flaccidity, hypotonia

• tendon reflexes

•Hypo- /no tendon

•+ Babinski sign

reflex

•little,if any,muscle

• - Babinski sign

atrophy

•muscle atrophy

•no fasiculation

•fasiculation of
involved muscle

24-Feb-14

Dr. Ashok Solanki

23
VISCERAL REFLEXES







PUPILLARY REFLEXES:
DIRECT LIGHT REFLEX
INDIRECT OR CONSENSUAL LIGHT REFLEX
ACCOMODATION REFLEX: CONSTRICTION
OF PUPIL, CONVERGENCE OF EYE BALLS,
INCREASE IN ANTERIOR CURVATURE OF
LENS
CILIOSPINAL REFLEX: STIMULATION OF
SKIN IN NECK –DILATATION OF PUPILS
OCULOCARDIAC REFLEX: PRESSURE OVER
EYEBALLS - BRADYCARDIA

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Dr. Ashok Solanki

24
PATHOLOGICAL REFLEXES

BABINSKI’S SIGN +
Dorsiflexion of great toe and fanning of
other toes.
 CLONUS
 PENDULAR MOVEMENTS


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1. receptors sense
Flexor reflex (Withdrawal, "hot stove")
pain
2. sensory impulse to
spinal cord
3. synapse to
association neuron,
synapse to motor
neurons


polysynaptic

4. motor neurons to
flexor muscles to
5. withdraw offended
body part from
stimulus
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Spinal reflexes
Static stretch reflex- maintain the tone
Maintain constant degree of muscle
contraction (Tone)
Continuous static receptor signal →
transmitted via both primary and
secondary neurons → S.C → continuous
command by static gamma motor
neurons → Tone.
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Dr. Ashok Solanki

Normal tone is due to continuous dischrge

31
Stretch reflex 2 types
-Response that is transmitted:
Dynemic:
-when there is change in the length of the spindle
receptor (stretching of the sensory receptor area of the
muscle spindle by stretching of the muscle spindle or the
whole muscle). Detect Change in length.
-transmitted by the primary fiber Aα type
Static
continuous information about the length of the muscle
(not the change in length).
transmitted by both the primary Aα and secondary (Aβ
and Aγ)
24-Feb-14

Dr. Ashok Solanki

32
APPLIED:
Decreased (hypoactive) stretch reflex:
Destruction of sensory or motor nerve to the
muscle
Stimulation of inhibitory areas in brain

Inhibition of facilitatory areas in the brain
Hypothyroidism

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Dr. Ashok Solanki

33
Importance or use of stretch
reflex:
 1.

Tone maintenance
 2. Maintenance of posture
 3. Control of voluntary movements

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Dr. Ashok Solanki

34
What are the components of reflex
action?


Components of reflex
forms
reflex arc involving
1. receptor- sensory organ
2. afferent neuron3. centre
4. efferent neuron
5. effector organ

24-Feb-14

Dr. Ashok Solanki

35
Reflex arc


24-Feb-14

Diagram showing complete reflex arc

Dr. Ashok Solanki

36
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38
2. 5 Essential Components
of the Reflex Arc
Skin
Stimulus at distal
end of neuron

Spinal cord
(in cross section)
Sensory neuron

Receptor
Motor neuron
(a)

Integration
center
Interneuron

Effector

Dr. Ashok Solanki
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Dr. Ashok Solanki

39
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11 feb lect. reflexes, Ashok Solanki, asso. prof physio,

  • 1. REFLEX CONTENTS: DEFINITION  REFLEX ARC  TYPES/CLASSIFICATION OF REFLEXES  STRETCH REFLEX  MUSCLE SPINDLE  PROPERTIES OF REFLEXES  24-Feb-14 Dr. Ashok Solanki 1
  • 4. Nerve pathways Ascending Tracts Tract Signal function Dorsal columns Vibration, tactile sensation, conscious proprioception Spinocerebeller Spinothalamic (lateral and Proprioception anterior) Spinoreticular Spinomesencephalic Spino-cervico-thalamic Spinohypothalamic Pain, temperature, itch (lateral), crude touch (anterior) Pain Pain Pain (touch?) Pain
  • 5. Structure of spinal cord 24-Feb-14 Dr. Ashok Solanki 5
  • 6. Spinal cord     Fetal 3rd month: ends at coccyx Birth: ends at L3 Adult position at approx L1-2 during childhood End: conus medullaris    This tapers into filum terminale of connective tissue, tethered to coccyx Spinal cord segments are superior to where their corresponding spinal nerves emerge through intervetebral foramina (see also fig 17.5, p 288) Denticulate ligaments: lateral shelves of pia mater anchoring to dura (meninges: more later) http://www.apparelyzed.com/spinalcord.html
  • 7. Spinal nerves continued        Divided based on vertebral locations 8 cervical 12 thoracic 5 lumbar 5 sacral 1 coccygeal Cauda equina (“horse’s tail”): collection of nerve roots at inferior end of vertebral canal
  • 8. Classified as According to centre IN THE SPINAL CORDseg, inter, supra. According to functionflexor, extensor, postural R. Clinicallysupreficial, deep, visceral No. of synapse involved. Mono and polysynaptic According to origin– spinal cord, brain stem, cortical etc. Conditional and unconditional – since birth  Rapid, stereotyped, invountary response to a sensory stimuli Dr. Ashok . consciouslly or unconsciousllySolanki 24-Feb-14 8
  • 9. CLASSIFICATION CONDITIONED (ACQUIRED)/ UNCONDITIONED(SINCE BIRTH)  CEREBELLER, CORTICAL, MIDBRAIN, SPINAL  SOMATIC:FLEXOR , EXTENSOR VISCERAL: AUTONOMIC  MONOSYNAPTIC , POLYSYNAPTIC  SUPERFICIAL, DEEP, VISCERAL, PATHOLOGICAL  SEGMENTAL, INTERSEGMENTAL, SUPRASEGMENTAL  24-Feb-14 Dr. Ashok Solanki 9
  • 12. Functions or reflex action Maintain the homeostasis- b.p regulation, heart rate, digestive , autonomic reflexes  Automatic actions  Balance and posture  Reflex maintining the movements -eyes  24-Feb-14 Dr. Ashok Solanki 12
  • 13. REFLEX ARC ANATOMICAL NERVOUS PATHWAY OF REFLEX IS CALLED REFLEX ARC. RECEPTOR SENSORY / AFFERENT NERVE CENTER EFFERENT / MOTOR NERVE EFFECTOR ORGAN  * BELL-MAGENDIE LAW: DORSAL ROOTS ARE SENSORY & VENTRAL ROOTS ARE MOTOR. 24-Feb-14 Dr. Ashok Solanki 13
  • 14. SUPERFICIAL REFLEXES CORNEAL AND CONJUNCTIVAL REFLEX  PHARYNGEAL REFLEX  PALATAL REFLEX  ABDOMINAL RELEX  PLANTAR REFLEX: Scratch over the outer edge of sole cause plantar flexion and adduction of all toes and dorsiflexion and inversion of foot.( L5,S1)  ANAL REFLEX  24-Feb-14 Dr. Ashok Solanki 14
  • 15. DEEP REFLEXES JAW JERK: 5TH CRANIAL NV NUCLEI  BICEPS JERK: C5,6  TRICEPS JERK: C6,7  SUPINATOR JERK: C5,6  KNEE JERK: L2,3,4  ANKLE JERK: S1,2  24-Feb-14 Dr. Ashok Solanki 15
  • 16. Reflex Arc Specific nerve impulse pathway  5 components of reflex arc  receptor  sensory neuron  integrating center  motor neuron  effector  24-Feb-14 Dr. Ashok Solanki 16
  • 17. PROPERTIES          ONE WAY CONDUCTION SUMMATION: SPATIAL, TEMPORAL OCCLUSION SUBLIMINAL FRINGE RECRUITMENT AFTERDISCHARGE REBOUND PHENOMENON FATIGUE RECIPROCAL INNERVATION AND RECIPROCAL INHIBITION 24-Feb-14 Dr. Ashok Solanki 17
  • 18. Flexor (withdrawal) Reflex     24-Feb-14 Dr. Ashok Solanki Step on tack (pain fibers send signal to spinal cord Interneurons branch to different spinal cord segments Motor fibers in several segments are activated More than one muscle group activated to lift foot off of tack 18
  • 19. Crossed Extensor Reflex     24-Feb-14 Dr. Ashok Solanki Lifting left foot requires extension of right leg to maintain one’s balance Pain signals cross to opposite spinal cord Contralateral extensor muscles are stimulated by interneurons to hold up the body weight Reciprocal innervation - when extensors contract flexors relax, etc 19
  • 20. Clinical Considerations Checking a patient’s reflexes may help to detect disorders/injury  Plantar flexion reflex -- stroke the lateral margin of the sole  normal response is curling under the toes  abnormal response or response of children under 18 months is called Babinski sign (upward fanning of toes due to incomplete myelination in child)  24-Feb-14 Dr. Ashok Solanki 20
  • 21. Inverse stretch reflex Golgi tendon organ- 2 to 15 in each muscle.  Responds to tension and not the length  The Golgi tendon reflex is a protective reflex  rise in tension is sensed by the Golgi tendon a which stimulates the Ib stimulates the I-b afferents  stimulate the inhibitory interneurons  inhibit the α-motoneuron discharge to  24-Feb-14 Dr. Ashok Solanki 21
  • 22. INVERSE STRETCH REFLEX/ AUTOGENIC INHIBITION  WHEN A MUSCLE IS STRETCHED, IT CONTRACTS BUT IF THE STRETCH IS MAINTAINED (CONTINUED), THE MUSCLE RELAXES. 24-Feb-14 Dr. Ashok Solanki 22
  • 23. UMN lesions LMN lesions •weakness, paralysis •weakness, paralysis •spasticity •flaccidity, hypotonia • tendon reflexes •Hypo- /no tendon •+ Babinski sign reflex •little,if any,muscle • - Babinski sign atrophy •muscle atrophy •no fasiculation •fasiculation of involved muscle 24-Feb-14 Dr. Ashok Solanki 23
  • 24. VISCERAL REFLEXES     PUPILLARY REFLEXES: DIRECT LIGHT REFLEX INDIRECT OR CONSENSUAL LIGHT REFLEX ACCOMODATION REFLEX: CONSTRICTION OF PUPIL, CONVERGENCE OF EYE BALLS, INCREASE IN ANTERIOR CURVATURE OF LENS CILIOSPINAL REFLEX: STIMULATION OF SKIN IN NECK –DILATATION OF PUPILS OCULOCARDIAC REFLEX: PRESSURE OVER EYEBALLS - BRADYCARDIA 24-Feb-14 Dr. Ashok Solanki 24
  • 25. PATHOLOGICAL REFLEXES BABINSKI’S SIGN + Dorsiflexion of great toe and fanning of other toes.  CLONUS  PENDULAR MOVEMENTS  24-Feb-14 Dr. Ashok Solanki 25
  • 29. 1. receptors sense Flexor reflex (Withdrawal, "hot stove") pain 2. sensory impulse to spinal cord 3. synapse to association neuron, synapse to motor neurons  polysynaptic 4. motor neurons to flexor muscles to 5. withdraw offended body part from stimulus 24-Feb-14 Dr. Ashok Solanki 29
  • 31. Spinal reflexes Static stretch reflex- maintain the tone Maintain constant degree of muscle contraction (Tone) Continuous static receptor signal → transmitted via both primary and secondary neurons → S.C → continuous command by static gamma motor neurons → Tone. 24-Feb-14 Dr. Ashok Solanki Normal tone is due to continuous dischrge 31
  • 32. Stretch reflex 2 types -Response that is transmitted: Dynemic: -when there is change in the length of the spindle receptor (stretching of the sensory receptor area of the muscle spindle by stretching of the muscle spindle or the whole muscle). Detect Change in length. -transmitted by the primary fiber Aα type Static continuous information about the length of the muscle (not the change in length). transmitted by both the primary Aα and secondary (Aβ and Aγ) 24-Feb-14 Dr. Ashok Solanki 32
  • 33. APPLIED: Decreased (hypoactive) stretch reflex: Destruction of sensory or motor nerve to the muscle Stimulation of inhibitory areas in brain Inhibition of facilitatory areas in the brain Hypothyroidism 24-Feb-14 Dr. Ashok Solanki 33
  • 34. Importance or use of stretch reflex:  1. Tone maintenance  2. Maintenance of posture  3. Control of voluntary movements 24-Feb-14 Dr. Ashok Solanki 34
  • 35. What are the components of reflex action?  Components of reflex forms reflex arc involving 1. receptor- sensory organ 2. afferent neuron3. centre 4. efferent neuron 5. effector organ 24-Feb-14 Dr. Ashok Solanki 35
  • 36. Reflex arc  24-Feb-14 Diagram showing complete reflex arc Dr. Ashok Solanki 36
  • 39. 2. 5 Essential Components of the Reflex Arc Skin Stimulus at distal end of neuron Spinal cord (in cross section) Sensory neuron Receptor Motor neuron (a) Integration center Interneuron Effector Dr. Ashok Solanki 24-Feb-14 Dr. Ashok Solanki 39