The document describes various types of network topologies including linear, mutual, telephone tree, and military squad networks. It discusses key network concepts like degree of separation and hubs. Degree refers to how connected a node is, and separation refers to the distance between nodes. Hubs are highly connected nodes that help connect other nodes. The document also discusses social networks and how examining hubs can help understand how diseases spread through networks.
2. Ewa
Balaji
Albert
Michele
Project M
Marc O'Brien
Ben Gaydos
Boston Progress
Arts Collective
Janet
Jonah
Alex
Becky
Karen
Karen Stein
A Better World by
Design
Design That
Matters
D-Lab
Nadia
Sandra
UC Berkeley
Rachel
Kopernik
Elizabeth
Donny
MIT
Jackie
Appropedia
Orgs TEL wants to
or could
work with
The TEL Team
Professional
Networking Hubs
Designers,
Coders, etc.
Waka
Nokero
Selco
Essmart
Sameer
Elise
Diana
JICA
Raiki
Translators Without
Borders
Engineering for
Change
Steve
Lesley University
John
Jo
Operation
Groundswell
PATH
The TEL Network
3. Systems
Thinking
systems
elements
interrelations
purpose
feedback
Communications
simple
d the core
use analogies
concrete
unexpected
expose knowledge
gaps
Behavorial Change
direct the rider
send destination
postcards
d bright spots
script
mo
motivate the
elephant
shrink the change
d the feeling
appeal to idenity
engineer early
successes
help people grow
shape the path
make it social
Impact
know your
mission
measure the
right thing
measure it well
verb
target
outcome
impact from a thing
is it needed?
will it get to those
who need it?
will they use it
correctly?
leverage points
traps
opportunities
design
thinking
ask stupid
questions
make hope visible
jump fences
smart
recombinations
abductive
reasoning
drift
fail early, fail often
harvest ideas, edit
applications compelling
experience
framework
generative
metaphors
combine familiar
and surprising
embrace
constraints
forced
prioritization
create mystery
credible
human-scale
principle
authority
antiauthority
the Sinatra test
testable
credentials
the Velcro theory of
memory
blac
emotion
violate schemas
solution focus
twe
envir
stories
build a culture
stocks
flows
23. Information is directional (inbound and outbound ties)
e Telephone Tree
Creates cascade effect
Reduces number of steps
24. Squad is more intra-connected
than inter-connected with other squads
e Military Squad
Tightly interconnected groups
Two-way tie between all members of squad
34. 34
links connecting the ki neighbors of node i to each other, represents
how nodes interconnect26. The Ci value of 0.24 measured for our net-
work indicates strong clustering27. Nodes with the largest numbers of
links were actin (33 interactions), PtdIns(4,5)P2 (20), SLC9A3R2 (12),
CALM (9), RDX (8) and Ca2+ (8).
ERM proteins28, and binding was indeed stronger to
threonine-to-aspartate mutation that mimics the acti
phorylation (Fig. 5b and Supplementary Fig. 8). In bu
cilia, RDX is activated by PtdIns(4,5)P2 and phosphoryla
in a narrow band above basal tapers, at the site of the
Ptdlns(4,5)P2
PLS1
ANXA6
Known interaction
Bundle protein paralog
Hypothetical
Molecules per
stereocilium
105
104
103
102
10
PIP4K2B
Figure 4 Interaction network for h
proteins. Symbols (nodes) represen
proteins or second messengers; on
with two or more interactions are p
the exception of OCM and CALB2.
labels indicate deafness-associate
Node colors indicate functional cla
(same key as in Fig. 2b); node sym
represents protein abundance in b
PtdIns(4,5)P2 and cyclic AMP are
diamond node symbols. Solid links
interactions validated with literatu
Supplementary Table 3 lists all int
evidence. Dotted links correspond
involving paralogs of bundle protei
links represent hypothetical intera
example, SLC9A3R2 interactions
The layout of the plot is controlled
density of links between nearby no
distribution of nodes and links in t
well by a power law, which indicat
plot contains a few highly connect
(hubs) and many other less-connec
Supplementary Figure 7 reproduce
figure with each link hyperlinked t
reference supporting the interactio
37. Terms
A Social Network: consists of all the connections and ties within
a group or collection of groups
A group is a collection of individuals defined by a common
attribute (it need not contain information about connections)
39. Ewa
Balaji
Albert
Michele
Project M
Marc O'Brien
Ben Gaydos
Boston Progress
Arts Collective
Janet
Jonah
Alex
Becky
Karen
Karen Stein
A Better World by
Design
Design That
Matters
D-Lab
Nadia
Sandra
UC Berkeley
Rachel
Kopernik
Elizabeth
Donny
MIT
Jackie
Appropedia
Orgs TEL wants to
or could
work with
The TEL Team
Professional
Networking Hubs
Designers,
Coders, etc.
Waka
Nokero
Selco
Essmart
Sameer
Elise
Diana
JICA
Raiki
Translators Without
Borders
Engineering for
Change
Steve
Lesley University
John
Jo
Operation
Groundswell
PATH
The TEL Network
46. To figure out how
a disease is spreading,
look for hubs.
47. With Bird Flu, 'Right Now, Anything Is
Possible'
April 19, 2013 5:36 AM
by RICHARD KNOX
Listen to the Story
Morning Edition 4 min 22 sec
ChinaFotoPress/Getty Images
i
An international dream team of flu experts assembled in China
today.
Underscoring the urgency that public health agencies feel about the
emergence of a new kind of bird flu, the team is headed by Dr. Keiji
Fukuda, the World Health Organization's top influenza scientist.
Before he left Geneva, Fukuda explained the wide-open nature of