3. Onstabiele repeat sequenties Dynamische mutaties

5. 5 – 35: stabiel 35 – 49: premutatie at risk > 50: mutatie: mild, klassiek, congenitaal

6. 5 - 50 50 - 200 > 200

13. Rassen ?

15. LEBERs Opticusatrofie

27. (innesteling)

31. PRADER-WILLI syndroom Incidentie: 1 op 12000

41. Figure 1 Typical phenotypes of Angelman (left) and Prader-Willi (right) syndrome patients. The difference between them belies the fact they they are caused by the same chromosomal deletion. (From Nicholls, 1994; Photographs courtesy of R. D. Nicholls).

42. Angelman syndroom (AS)

47. oorstreepjes

49. Epigenetica

50. 2. Darwin: DNA via eiwitten naar kenmerken: éénrichting!

53. Cardio en diabetes: Multifactoriele aandoeningen