The document summarizes the anatomy and histology of the pancreas, gallbladder, and biliary tree. It describes the key structures and cell types of the exocrine pancreas including acinar cells and ducts. It also describes the islets of Langerhans containing alpha, beta, and delta cells that make up the endocrine pancreas. Additionally, it outlines the histology of the gallbladder including its epithelial layer, lamina propria, and muscularis externa layers. Finally, it briefly discusses the structures that make up the biliary tree including bile ducts and ductules.

1. PANCREAS

2. ANATOMY
 DELICATE LOOSE C.T CAPSULE
 SOFT LOBULATED
 HEAD NECK & TAIL
 PANCREATIC DUCT
 HEPATO PANCREATIC AMPULLA

3. PANCREAS
PARENCHYMA ENDOCRINE EXOCRINE
STROMA LOOSE C.T. WITH NUMEROUS
B.V. MAST CELLS

4. EXOCRINE PANCREAS
 PANCREATIC ENZYMES
 SEROUS GLAND
 BRANCHED ACINAR
 SPHERICAL CLUSTER OF PYRAMIDAL
CELLS
 CENTROACINAR CELLS
 INTRAACINAR PART OF INTERCALATED DUCT

5. SEROUS MUCOUS
 PYRAMIDAL  COLUMNAR
 PURPLISH RED WITH BASAL  LIGHTLY EOSINOPHILIC
BASOPHILIA
 ROUND BASAL NUCLEUS  FLATTENED PERIPHERAL
NUCLEUS
 CELL OUTLINES NOT CLEAR  CLEAR
 LUMEN INDISTINCT
 ZYMOGEN GRANULES  DISTINCT
 MYOEPITHELIAL CELLS are  MUCINOGEN VESICLES
PROMINENT  NOT PROMINENT

6. SEROUS MUCOUS

7. SEROUS MUCOUS
 Apical microvilli  Apical plasma
 Laterally intercellur membrane smooth
canaliculi, junctional  Intercellular canaliculi
complexes & rare
infoldings  Dense large closely
 Golgi complex, Rer packed & ill defined
 Small discrete  > AGAGS
granules secretion
 < AGAGS

8. SEROUS MUCOUS

9. DUCT SYSTEM
 INTERCALATED SIMPLE CUBOIDA;
 INTRALOBULAR NO STRIATED DUCT
 INTERLOBULAR
LOW COLUMNAR ENTERO ENDOCRINE GOBLET
 MAIN PANCREATIC DUCT

11. CONTROL OF EXOCRINE
SECRETION
 HORMONAL
 SECRETIN,CCK
 NEURONAL
SYMPATHETIC REGULATION OF PANCREATIC BLOOD FLOW
PARASYMPATHETIC --- ACINAR & CENTROACINAR CELLS
 HCO3 & H2O
 DUCTAL & CENTROACINAR CELLS
 VAGAL CHOLINERGIC HORMONAL SECRETIN
 ENZYMES ACINAR CELLS
 VAGAL CHOLINERGIC HORMONAL CCK

12. ENDOCRINE PANCREAS
 ISLETS OF LANGERHANS
 CLUSTERS OF PALE STAINING POLYHEDRAL CELLS
 > TAIL
 FENESTRATED CAPILLARIES AUTONOMIC
INNERVATION
 ALPHA BETA & DELTA ( MALLORY AZAN)
 BETA 70% CENTRE INSULIN
 ALPHA 10-15% PERIPHERY GLUCAGON,. GIP, CCK, ACTH
 DELTA 10-15% PERIPHERY SOMATOSTATIN GASTRIN
 CONTROL OF ENDOCRINE PANCREAS
 PARASYMPATHETIC INCREASES SECRETION OF INSULIN & GLUCAGON
 SYMPATHETIC INCREASES GLUCAGON BUT INHIBITS INSULIN

15. GALL BLADDER

16. HISTOLOGY
 MUCOSAL FOLDS (EMPTY)
 COLUMNAR EPITHELIUM WITH MICROVILLI APICAL
JUNCTIONAL COMPLEX & MITOCHONDRIA Na K ATPase
 LAMINA PROPRIA VASCULAR FENESTRATEDCAPILLARIES
& CELLULAR (PLASMA CELLS & LYMPHOCYTES)
 MUSCULARIS EXTERNA
 RANDOMLY ORIENTED SMOOTH MUSCLES WITH BUNDLES OF
COLLAGEN & ELASTIC FIBER
 SEROSA / ADVENTITIA
 THICK DENSE C.T. BLOOD & LYMPH VESSELS & NERVES
 ABSORPTION OF H2O & ELECTROLYTE

18. BILIARY TREE
 BILE CANALI CULI
 CANALS OF HERRING
 INTER LOBULAR BILE DUCTS
 RIGHT & LEFT HEPATIC DUCTS
 CYSTIC DUCT BILE DUCT

19. HISTOLOGY
 GROOVES B/W ADJACENT HEPATOCYTES
JUNCTIONAL COMPLEX
 SIMPLE CUBOIDAL EPITHELIUM WITH
BASAL LAMINA MICROVILLI
 CUBOIDAL TO COLUMNAR DENSE
CONNECTIVE INVESTMENT WITH
SMOOTH MUSCLE