1. Chronic candidiasis Done by : AbdulrahmanSulaiman Al-Otaiq

2. Chronic candidiasis 1. CHRONIC ATROPHIC CANDIDIASIS Denture stomatitis (denture sore mouth) Angular cheilitis Median rhomboid glossitis 2. CHRONIC MULTIFOCAL CANDIDIASIS 3. Chronic hyperplastic C (candidaleukoplakia) 4- chronic mucocutaneouscandidiasis(secondry to systemic disease specially endocrine diseases)

3. Predisposing factor of chronic candidiasis: poor oral hygiene Xerostomia Compromised Immune system. Recent antibiotic treatment Dental appliance Early infancy AIDS Corticosteroid Pregnancy Anemia Diabetes mellitus

4. Denture sore mouth Denture stomatitisis a common form of oral candidiasis Manifests as a diffuse inflammation of the maxillary denture-bearing areas . Often associated with angular cheilitis.

5. At least 70% of individuals with clinical signs of denture stomatitis exhibit fungal growth, and this condition most likely results from yeast colonization of the oral mucosa, combined with bacterial colonization.

8. Three progressive clinical stages of denture sore : 1. numerous palatal petechiae . 2. displays amore diffuse erythema involving most (if not all) of the denture-covered mucosa. 3. includes the development of tissue granulation or nodularity(papillary hyperplasia) commonly involving the central areas of the hard palate and alveolar ridges.

10. Denture sore mouth is rarely found under a mandibular denture. One possible explanation for this is that the negative pressure that forms under the maxillary denture excludes salivary antibody from this region, and yeast may reproduce,undisturbed, in the space between the denture and mucosa.

11. Angular Cheilitis is the term used for aninfectioninvolving the lip commissures. There is frequently a coexistent denture stomatitis, and angular cheilitis is uncommonin patients with a natural dentition.

12. Etiologic of Angular Cheilitis reduced vertical dimension wiche may case nutritional deficiency (iron deficiency anemia and vitamin B or folic acid deficiency) sometimes referred to as perlèche (more rarely) diabetes, neutropenia, and AIDS, Staphylococcus and beta hemolytic Streptococcus.

13. Angular cheilitis

14. Erythematous patches of atrophic papillae located in the central area of the dorsum of the tongue Considered a form of chronic atrophic candidiasis These lesions were originally thought to be developmental in nature but are now considered to be a manifestation of chronic candidiasis. Median Rhomboid glossitis

15. Median Rhomboid glossitis

17. These are most often seen in immunocompromisedindividuals or in patients with predisposing factors suchas ill-fitting dentures.