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Educator’s guide on
                            Malaria
                         (Tools’ information)



AUTHORS   FUNDED BY:
Table of Content

     I. Introduction .............................................................................................................................. 3
     II. The tools ................................................................................................................................. 3
     1.    Video Game – Stop Malaria ................................................................................................ 4
     2.    Video 1 – Working for a malaria-free world! ........................................................................ 5
     3.    Video 2 – A shelter from malaria ......................................................................................... 7
     4.    Video 3 – Facing an underestimated malaria ...................................................................... 8
     5.    Experiment – Investigate a malaria vaccine ........................................................................ 9
     6.    Experiment protocol – Investigate a malaria vaccine ........................................................ 10
     7.    Video DECIDE – Malaria: ethical issues ........................................................................... 11
     8.    Game DECIDE – Malaria: ethical issues ........................................................................... 12




                          Toward a malaria-free world - 2 – Tools’ Information
I. Introduction
This document provides information on the tools that are available on the Xplore Health portal for the
second module concerning malaria. For each tool, we provide an ID table and explanation on how to
use the tool in class and interact with the curriculum.



II. The tools
The tools that have been created for the use of teachers and students in order to help them in their
familiarization process of malaria are listed and explained below.

The tables provided in this document describe each tool, provides a link to the tool and gives
suggestions on how the tool can be implemented in class: pre-, during, and post-exercises.

The tools are the following:


1. Video Game – Stop Malaria-
2. Video 1 – Working for a malaria-free world!
3. Video 2 – A shelter from malaria
4. Video 3 – Facing an underestimated malaria
5. Experiment – Investigate a malaria vaccine
6. Experiment protocol – Investigate a malaria vaccine
7. Video DECIDE – Malaria: ethical issues
8. Game DECIDE – Malaria: ethical issues




                      Toward a malaria-free world - 3 – Tools’ Information
1. Video Game – Stop Malaria

       Tool name             Video Game – Stop Malaria

Link to tool / information
                             http://www.xplorehealth.eu/en/media/stop-malaria
       on the tool

                 Description                             Activities in which this tool can be used

                                                  Pedagogical objectives:
                                                          Knowledge on how to developed methods to
                                                           prevent and cure malaria disease
                                                          Awareness of importance of population
                                                           education.
Key messages:                                             Awareness of the role of population
                                                           epidemiologic research for drugs validation.
      Significance of malaria disease for
       population, especially in poor countries           Understanding how to optimize costs of
                                                           introducing new drugs.
Concepts that appear:
      How to stop malaria - using Africa as an   Time needed: 45 minutes
       example
                                                  Process:
      Drug resistance
                                                          Introduction
      Investment in new drugs and diagnostic
       methods                                            Game
      Information about anti mosquito covers             Summary and conclusions
       and spray
                                                  Outcomes

                                                          Awareness of malaria disease deadly effects
                                                           and risk especially for Africa region
                                                          Using communication media different than
                                                           “paper docs”
                                                          Using computer and web tools.




                     Toward a malaria-free world - 4 – Tools’ Information
2. Video 1 – Working for a malaria-free world!

       Tool name              Video 1 – Working for a malaria-free world!

Link to tool / information
                              http://www.xplorehealth.eu/en/media/working-malaria-free-world
       on the tool

                 Description                               Activities in which this tool can be used

                                                   Pedagogical objectives (benefits of this tool for
                                                   students and teachers):
                                                   Conceptual points:
                                                            Understanding malaria
                                                            Eradication of a disease.
                                                            Role of research.
                                                   Procedimental points:

Key messages:                                               Searching skills
Concepts that appear:                                       Information process skills
      ‘Life-cycle’ of Malaria. Vectors and
       hosts.
                                                   Time needed to implement this tool:
      Pathogenesis of Malaria.
                                                             Two 50’ sessions
      Geographical distribution and inequality.
      Natural immunity                            Process (how can this tool be used in class -
                                                   suggestions):
      Research paths.
                                                   First session
                                                            Viewing video
                                                            Search for related additional information at the
                                                             Internet.
                                                            Task. Produce a multimedia product in an
                                                             investigative journalistic format.
                                                   Second session
                                                            Public review of products.
                                                            Debate and finding a consensus.




                     Toward a malaria-free world - 5 – Tools’ Information
Outcomes(Students will now have knowledge of):
                                Training of capacity of Information analysis.
                                Promote synthesis capabilities.
                                Using communication media different than
                                 “paper docs”
                                Using computer and web tools.




Toward a malaria-free world - 6 – Tools’ Information
3. Video 2 – A shelter from malaria

       Tool name             Virtual experiment 1 – The Unusual Suspect

Link to tool / information
                             http://www.xplorehealth.eu/en/media/shelter-malaria
       on the tool

                 Description                              Activities in which this tool can be used

                                                   Pedagogical objectives:
                                                           Awareness of how vaccination acts against
                                                            malaria
                                                           Understanding of human resistance
                                                            mechanisms
Key messages:                                              Knowledge about scale of malaria vaccination
                                                            research in Africa
      Developing of revolutionary first of kind
       anti malaria vaccination with 50%                   Importance of international cooperation in
       performance                                          health protection.
Concepts that appear:
                                                   Process:
      Vaccination against malaria
                                                           Introduction
      Methods to improve drug’s effectiveness
                                                           Presentation of video “Shelter malaria”
      Testing of immunologic reaction within
                                                           Summary
       young children
      Lymphocyte B and T and antibodies role      Time needed: 45 minutes
       in human health protection
                                                   Outcomes

                                                           Knowledge how new vaccinations can help to
                                                            protect people in Africa
                                                           Using communication media different than
                                                            “paper docs”
                                                           Using computer and web tools.




                     Toward a malaria-free world - 7 – Tools’ Information
4. Video 3 – Facing an underestimated malaria

       Tool name              Video 3 – Facing an underestimated malaria

Link to tool / information
                              http://www.xplorehealth.eu/en/media/facing-underestimated-malaria
       on the tool

                  Description                             Activities in which this tool can be used

                                                  Pedagogical objectives:
                                                           Gathering information on malaria and its
                                                            causative agents : Plasmodium falciparum
                                                            and vivax ;
                                                           Understanding how to fight off Plamsodium
                                                            vivax in pregnant women;
Key messages:
                                                           Understand how antibodies can be used to
      Understanding how Plasmodium vivax                   diagnose the disease with a helpful and
       affects pregnant women to better fight               practical simulation: antibody as a marker of
       off the disease                                      the disease.
      European union coordinates a project
       called “Pregvax” which involves nine       Process:
       European and non European centres
                                                           Prior to the video, a research on malaria is a
Concepts that appear:                                       must
               What is an antibody?                       Research on what is an antibody is needed to
                                                            better conduct the rest of the activity
               How can an antibody be an
                effective tool in assessing the            Video
                efficiency of the immune
                response towards Falciparum       Time needed : 45 min
                and in assessing the efficiency
                of a putative vaccine candidate   Outcomes :

                                                  Be acquainted with malaria; acquainted with a
                                                  European based Project aiming at fighting off malaria
                                                  in poverty affected countries: malaria is a worldwide
                                                  concern.




                      Toward a malaria-free world - 8 – Tools’ Information
5. Experiment – Investigate a malaria vaccine

       Tool name             Experiment 1 – Investigate a malaria vaccine

Link to tool / information
                             http://www.xplorehealth.eu/en/media/investigate-malaria-vaccine
       on the tool

                 Description                           Activities in which this tool can be used

                                                  Pedagogical objectives:
                                                  Understanding what a vaccine is;
                                                  Understanding the main aspects of the immune
                                                  system and how its components come into play to
                                                  ward off intruders;
                                                  Understanding the life cycle of plasmodium and its
                                                  various form it can take throughout its life;
Key messages:
                                                  Understanding that plasmodium proteins are the
Concepts that appear:
                                                  molecule part used in vaccine;
       What is a vaccine and what is it made
       of?                                        How to read a report analysis once the experiment is
                                                  completed?
       How does the immune system come
       into play to fight off the infection?      Process:
       What are B and T lymphocytes and their     Introduction to immune system and vaccine; through a
       respective role in destroying the          questionnaire and a web search conducted activity
       pathogen?
                                                  Game
       What is the Plasmodium life cycle once
       one has been infected?                     Conclusion
       What is the best part of the parasite to
                                                  Time needed: 30 min
       use as a putative and effective vaccine?

                                                  Outcomes

                                                  Understanding how a candidate vaccine is made and
                                                  how it is tested for assessing its effectiveness.
                                                  Understanding the process and steps in constructing
                                                  such a vaccine.




                     Toward a malaria-free world - 9 – Tools’ Information
6. Experiment protocol – Investigate a malaria vaccine

       Tool name             Experiment protocol – Investigate a malaria vaccine

Link to tool / information   http://www.xplorehealth.eu/en/investigate-vaccine-
       on the tool           malaria?arg0=resources-for-educators

                 Description                             Activities in which this tool can be used

                                                 Pedagogical objectives:
                                                 Conceptual points
                                                          Understanding ELISA
                                                 Procedimental points
                                                          Lab techniques
                                                          Safety skills
                                                          Interpretation and report of results

                                                 Process:
Key messages:
Concepts that appear:                            First session
      Immunology                                         Lab protocol
      Antigen-Antibody reactions                Second session
      ELISA test                                         Reporting and analysing results

                                                 Time needed:
                                                           Two 50’ sessions

                                                 Outcomes

                                                          Knowledge of basic immunology aspects

                                                          Knowledge of ELISA test capabilities in
                                                           research

                                                          Best lab and lab-safety skills.




                    Toward a malaria-free world - 10 – Tools’ Information
7. Video DECIDE – Malaria: ethical issues



        Tool name             Video DECIDE – Malaria: ethical issues

Link to tool / information
                              http://www.xplorehealth.eu/en/media/malaria-ethical-issues
       on the tool

                  Description                             Activities in which this tool can be used

                                                  Pedagogical objectives:
                                                  Conceptual points
                                                           Understanding the complexity of eradicating
                                                            malaria
                                                           The importance of interdisciplinary thinking
                                                            when solving health problems
Key messages:
                                                           Understanding the importance of health to
Malaria can be eradicated with economic and                 fight poverty and vice versa.
political support and we find even more
sufficient ways to fight the parasite.            Process:
Concepts that appear:                                      Watch video
Learn about the actions needed to bring down               Class discussion
malaria. And why malaria is linked to poverty.
                                                  Time needed: 30 minutes

                                                  Outcomes
                                                           Knowledge of the complexity of fighting
                                                            poverty and disease.
                                                           Working with health is also other than
                                                            producing drugs.




                     Toward a malaria-free world - 11 – Tools’ Information
8. Game DECIDE – Malaria: ethical issues

        Tool name             Game DECIDE – Malaria: ethical issues

                              http://www.xplorehealth.eu/en/playdecide-malaria?arg0=resources-for-
Link to tool / information    educators
       on the tool



                  Description                               Activities in which this tool can be used

                                                    Pedagogical objectives:
                                                    Health is other than laboratory and drugs it is also
                                                    about management: making priorities and providing
                                                    strategic actions.
Key messages:
You need several methods to fight malaria. If the   Process:
budget is low how would you prioritise between
                                                             Discussions in groups with about 4 to 8,
the tools at disposition.
                                                              although it works best with 5-6 people

Concepts that appear:
                                                    Time needed:
The students are set to reflect about what they
consider most important: prevention, treatment      80 minutes
and diagnosis or research and can you prioritise
between geographical areas?                         Outcomes

                                                             Knowledge of the complexity of fighting
                                                              diseases and the political dilemmas related to
                                                              prioritization.




                     Toward a malaria-free world - 12 – Tools’ Information
FUNDED BY:                               PROJECT PARTNERSBY:




WITH THE SUPPORT OF




                      Toward a malaria-free world - 13 – Tools’ Information

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Toward a malaria-free world - Tools' information

  • 1. Educator’s guide on Malaria (Tools’ information) AUTHORS FUNDED BY:
  • 2. Table of Content I. Introduction .............................................................................................................................. 3 II. The tools ................................................................................................................................. 3 1. Video Game – Stop Malaria ................................................................................................ 4 2. Video 1 – Working for a malaria-free world! ........................................................................ 5 3. Video 2 – A shelter from malaria ......................................................................................... 7 4. Video 3 – Facing an underestimated malaria ...................................................................... 8 5. Experiment – Investigate a malaria vaccine ........................................................................ 9 6. Experiment protocol – Investigate a malaria vaccine ........................................................ 10 7. Video DECIDE – Malaria: ethical issues ........................................................................... 11 8. Game DECIDE – Malaria: ethical issues ........................................................................... 12 Toward a malaria-free world - 2 – Tools’ Information
  • 3. I. Introduction This document provides information on the tools that are available on the Xplore Health portal for the second module concerning malaria. For each tool, we provide an ID table and explanation on how to use the tool in class and interact with the curriculum. II. The tools The tools that have been created for the use of teachers and students in order to help them in their familiarization process of malaria are listed and explained below. The tables provided in this document describe each tool, provides a link to the tool and gives suggestions on how the tool can be implemented in class: pre-, during, and post-exercises. The tools are the following: 1. Video Game – Stop Malaria- 2. Video 1 – Working for a malaria-free world! 3. Video 2 – A shelter from malaria 4. Video 3 – Facing an underestimated malaria 5. Experiment – Investigate a malaria vaccine 6. Experiment protocol – Investigate a malaria vaccine 7. Video DECIDE – Malaria: ethical issues 8. Game DECIDE – Malaria: ethical issues Toward a malaria-free world - 3 – Tools’ Information
  • 4. 1. Video Game – Stop Malaria Tool name Video Game – Stop Malaria Link to tool / information http://www.xplorehealth.eu/en/media/stop-malaria on the tool Description Activities in which this tool can be used Pedagogical objectives:  Knowledge on how to developed methods to prevent and cure malaria disease  Awareness of importance of population education. Key messages:  Awareness of the role of population epidemiologic research for drugs validation.  Significance of malaria disease for population, especially in poor countries  Understanding how to optimize costs of introducing new drugs. Concepts that appear:  How to stop malaria - using Africa as an Time needed: 45 minutes example Process:  Drug resistance  Introduction  Investment in new drugs and diagnostic methods  Game  Information about anti mosquito covers  Summary and conclusions and spray Outcomes  Awareness of malaria disease deadly effects and risk especially for Africa region  Using communication media different than “paper docs”  Using computer and web tools. Toward a malaria-free world - 4 – Tools’ Information
  • 5. 2. Video 1 – Working for a malaria-free world! Tool name Video 1 – Working for a malaria-free world! Link to tool / information http://www.xplorehealth.eu/en/media/working-malaria-free-world on the tool Description Activities in which this tool can be used Pedagogical objectives (benefits of this tool for students and teachers): Conceptual points:  Understanding malaria  Eradication of a disease.  Role of research. Procedimental points: Key messages:  Searching skills Concepts that appear:  Information process skills  ‘Life-cycle’ of Malaria. Vectors and hosts. Time needed to implement this tool:  Pathogenesis of Malaria. Two 50’ sessions  Geographical distribution and inequality.  Natural immunity Process (how can this tool be used in class - suggestions):  Research paths. First session  Viewing video  Search for related additional information at the Internet.  Task. Produce a multimedia product in an investigative journalistic format. Second session  Public review of products.  Debate and finding a consensus. Toward a malaria-free world - 5 – Tools’ Information
  • 6. Outcomes(Students will now have knowledge of):  Training of capacity of Information analysis.  Promote synthesis capabilities.  Using communication media different than “paper docs”  Using computer and web tools. Toward a malaria-free world - 6 – Tools’ Information
  • 7. 3. Video 2 – A shelter from malaria Tool name Virtual experiment 1 – The Unusual Suspect Link to tool / information http://www.xplorehealth.eu/en/media/shelter-malaria on the tool Description Activities in which this tool can be used Pedagogical objectives:  Awareness of how vaccination acts against malaria  Understanding of human resistance mechanisms Key messages:  Knowledge about scale of malaria vaccination research in Africa  Developing of revolutionary first of kind anti malaria vaccination with 50%  Importance of international cooperation in performance health protection. Concepts that appear: Process:  Vaccination against malaria  Introduction  Methods to improve drug’s effectiveness  Presentation of video “Shelter malaria”  Testing of immunologic reaction within  Summary young children  Lymphocyte B and T and antibodies role Time needed: 45 minutes in human health protection Outcomes  Knowledge how new vaccinations can help to protect people in Africa  Using communication media different than “paper docs”  Using computer and web tools. Toward a malaria-free world - 7 – Tools’ Information
  • 8. 4. Video 3 – Facing an underestimated malaria Tool name Video 3 – Facing an underestimated malaria Link to tool / information http://www.xplorehealth.eu/en/media/facing-underestimated-malaria on the tool Description Activities in which this tool can be used Pedagogical objectives:  Gathering information on malaria and its causative agents : Plasmodium falciparum and vivax ;  Understanding how to fight off Plamsodium vivax in pregnant women; Key messages:  Understand how antibodies can be used to  Understanding how Plasmodium vivax diagnose the disease with a helpful and affects pregnant women to better fight practical simulation: antibody as a marker of off the disease the disease.  European union coordinates a project called “Pregvax” which involves nine Process: European and non European centres  Prior to the video, a research on malaria is a Concepts that appear: must  What is an antibody?  Research on what is an antibody is needed to better conduct the rest of the activity  How can an antibody be an effective tool in assessing the  Video efficiency of the immune response towards Falciparum Time needed : 45 min and in assessing the efficiency of a putative vaccine candidate Outcomes : Be acquainted with malaria; acquainted with a European based Project aiming at fighting off malaria in poverty affected countries: malaria is a worldwide concern. Toward a malaria-free world - 8 – Tools’ Information
  • 9. 5. Experiment – Investigate a malaria vaccine Tool name Experiment 1 – Investigate a malaria vaccine Link to tool / information http://www.xplorehealth.eu/en/media/investigate-malaria-vaccine on the tool Description Activities in which this tool can be used Pedagogical objectives: Understanding what a vaccine is; Understanding the main aspects of the immune system and how its components come into play to ward off intruders; Understanding the life cycle of plasmodium and its various form it can take throughout its life; Key messages: Understanding that plasmodium proteins are the Concepts that appear: molecule part used in vaccine; What is a vaccine and what is it made of? How to read a report analysis once the experiment is completed? How does the immune system come into play to fight off the infection? Process: What are B and T lymphocytes and their Introduction to immune system and vaccine; through a respective role in destroying the questionnaire and a web search conducted activity pathogen? Game What is the Plasmodium life cycle once one has been infected? Conclusion What is the best part of the parasite to Time needed: 30 min use as a putative and effective vaccine? Outcomes Understanding how a candidate vaccine is made and how it is tested for assessing its effectiveness. Understanding the process and steps in constructing such a vaccine. Toward a malaria-free world - 9 – Tools’ Information
  • 10. 6. Experiment protocol – Investigate a malaria vaccine Tool name Experiment protocol – Investigate a malaria vaccine Link to tool / information http://www.xplorehealth.eu/en/investigate-vaccine- on the tool malaria?arg0=resources-for-educators Description Activities in which this tool can be used Pedagogical objectives: Conceptual points  Understanding ELISA Procedimental points  Lab techniques  Safety skills  Interpretation and report of results Process: Key messages: Concepts that appear: First session  Immunology  Lab protocol  Antigen-Antibody reactions Second session  ELISA test  Reporting and analysing results Time needed: Two 50’ sessions Outcomes  Knowledge of basic immunology aspects  Knowledge of ELISA test capabilities in research  Best lab and lab-safety skills. Toward a malaria-free world - 10 – Tools’ Information
  • 11. 7. Video DECIDE – Malaria: ethical issues Tool name Video DECIDE – Malaria: ethical issues Link to tool / information http://www.xplorehealth.eu/en/media/malaria-ethical-issues on the tool Description Activities in which this tool can be used Pedagogical objectives: Conceptual points  Understanding the complexity of eradicating malaria  The importance of interdisciplinary thinking when solving health problems Key messages:  Understanding the importance of health to Malaria can be eradicated with economic and fight poverty and vice versa. political support and we find even more sufficient ways to fight the parasite. Process: Concepts that appear:  Watch video Learn about the actions needed to bring down  Class discussion malaria. And why malaria is linked to poverty. Time needed: 30 minutes Outcomes  Knowledge of the complexity of fighting poverty and disease.  Working with health is also other than producing drugs. Toward a malaria-free world - 11 – Tools’ Information
  • 12. 8. Game DECIDE – Malaria: ethical issues Tool name Game DECIDE – Malaria: ethical issues http://www.xplorehealth.eu/en/playdecide-malaria?arg0=resources-for- Link to tool / information educators on the tool Description Activities in which this tool can be used Pedagogical objectives: Health is other than laboratory and drugs it is also about management: making priorities and providing strategic actions. Key messages: You need several methods to fight malaria. If the Process: budget is low how would you prioritise between  Discussions in groups with about 4 to 8, the tools at disposition. although it works best with 5-6 people Concepts that appear: Time needed: The students are set to reflect about what they consider most important: prevention, treatment 80 minutes and diagnosis or research and can you prioritise between geographical areas? Outcomes  Knowledge of the complexity of fighting diseases and the political dilemmas related to prioritization. Toward a malaria-free world - 12 – Tools’ Information
  • 13. FUNDED BY: PROJECT PARTNERSBY: WITH THE SUPPORT OF Toward a malaria-free world - 13 – Tools’ Information