In this guide you will have suggestions of lesson plans that have been designed by the Education National Coordinators using the Xplore Health materials.

1. Educator’s guide on
Drug development
(Lesson plans)
AUTHORS FUNDED BY:

2. Table of contents
I. Introduction 3
II. Lesson plans 3
1. Lesson plan 1: General information: The research in the field of drug
development, its phase’s and the role of researchers 4
2. Lesson plan 2: ELSA aspects of the development of a DRUG: access to
treatment in the context of globalisation 5
3. Lesson plan 3: ELSA aspects of the development of a drug:
economical/financial aspects of the development of drugs 7
4. Lesson plan 4: How is a drug DEVELOPED: the scientific production of a
drug target 9
Drug development - 2 – Lesson plans

3. I. Introduction
This document provides a number of suggestions of lesson plans on four topics linked to
drug development including time needed to organise the activities in class and the links
with different schools subjects.
II. Lesson plans
The lesson plans are meant to give teachers an idea of how the tools can be used within a
lesson. The idea is that suggestions for pre- and post-activities are collected in order to
give some inspiration.
The lesson plans will be preceded by a table displaying some general information
concerning the suggested plan, such as the age level of the students, the tools that are
used, etc.
The structure of the lesson plans is made in a way that objectives of the activities, as well
as materials needed for the implementation, the procedure of the activities and the timing
of each single activity are stated.
Abbreviations:
T: teacher Ss: students Ind: Individual work Gw: Groupwork
S: student OHT: overhead transparency Pw: Pairwork
Drug development - 3 – Lesson plans

4. Lesson plan 1: General information: The research in the field of
drug development, its phase’s and the role of researchers
General information:
Author of the lesson plan: Carlos de Paz Villasenín
Subject of the lesson: The research in the field of drug development, its
phase’s and the role of researchers
Age level of the students: 17-19
Xplore Health’s tools used: Video 1: The long and incredible story of a tablet
Virtual experiment 2 – Develop a drug!
Link with different school subjects/integration Biology, Chemistry, Informatics
in the curriculum:
Lesson Plan:
Activity Objective of Material, Inter- Procedure Time ∑
activity tools (min.)
needed action
Video Introduce theme Video 1: Gw All, teacher and pupils 10 10
The Story watch the video.
of a tablet
Teacher Introducing T -> Ss The teacher explains to 5 15
speech activity students how to work,
which is the activity and the
procedure to be followed
Workshop Discussing the Gw Students raise questions 5 20
approach of the Ss -> T about the development of
activity T -> Ss the activity.
Experiment Simulate real life Drug dev. Pw Students interact with the 20 40
(1) drugs virtual simulator to try to develop a
development experiment drug. Pair-work promotes
(workflow, (1) dialogue and strengths in
protocols, decision-making.
problems,...).
Students take
the role of
researchers.
Results Expression of Gw Each pair shows their 10 50
results results, and the problems
they may have had.
Drug development - 4 – Lesson plans

5. Lesson plan 2: ELSA aspects of the development of a DRUG:
access to treatment in the context of globalisation
General information:
Author of the lesson plan: Linda McCusker
Subject of the lesson: ELSA aspects of the development of a drug :
access to treatment in the context of globalisation
Age level of the students: 15-18 years old
Number of students in class: 20 students
Xplore Health’s tools used: Xplore Health Video 3 – Drug development and
ethics
Xplore Health Discussion continuum Game –
Access to Treatment
Link with different school Higher Biology, Higher Chemistry and PSE curricula
subjects/integration in the curriculum:
Pre-knowledge required by students: The research and development cycle of a drug,
acquired by using Xplore Health Virtual experiment
1 - Produce a drug target, Virtual experiment 2 –
Develop a drug!, Game and Video 1 The long and
incredible story of a tablet
Suggested background reading for XploreHealth/ Module 1:
Teacher:
How are drugs developed?
Ethical, legal and social aspects
Lesson Plan:
Activity Objective of Material, Inter- Procedure Time ∑
activity tools action (min.)
needed
Introduc- To explain to Xplore T→S Use class discussion and video to 10 10
tion students that Health Ss → give students an idea of the
the Video 3 Ss debates that are inspired, e.g.
production – Drug should all people have the same
and use of develop access to medicinal drugs
drugs ment regardless of where they live in the
inspires and world? Or If a person suffers from a
many ethics ‘rare’ disease should as much
debates with money be spent on drugs for their
Drug development - 5 – Lesson plans

6. regards to illness as is spent on more common
ELSA diseases which affect many more
people?
Class Students to Xplore T→S Introduction to resource 5 15
Activity be split into Health Gw Group discussions 30 45
5 groups of Discussi Ss →
4 students to on Ss
participate in continuu
the Xplore m Game
Health – Access
Discussion to
continuum Treatme
Game – nt
Access to
Treatment
Summa- Students will T→S 5 50
tion of provide
lesson feedback
from their
group
discussion
to rest of
class during
next lesson
Follow-up:
Activity Objective of Material Inter- Procedure Time ∑
activity and action (min.)
tools
needed
Introduction Quick recap for Decide Ss → Student presentations. 20 20
students reminding Game Ss
them that they are Phase 3
using the Decide –A
Game to look at the shared
ELSA aspects group
surrounding the respons
Drug development - 6 – Lesson plans

7. development of e
orphan drugs.
Continuation of
feedback session.
Class Class to decide on Decide Ss → Teacher facilitated class 20 40
Activity a shared group Game Ss discussion
response – can a Phase 3
class consensus be –A
agreed? shared
group
respons
e
Upload of To upload the class Decide Ss → Teacher supervised 10 50
class results shared group Game WWW session allowing students
to response to the Upload to upload class shared
www.playde website. results response to
cide.eu www.playdecide.eu
Lesson plan 3: ELSA aspects of the development of a drug :
economical / financial aspects of the development of drugs
General information:
Author of the lesson plan: Linda McCusker
Subject of the lesson: ELSA aspects of the development of a drug :
economical/financial aspects of the development of
drug
Age level of the students: 15-18 years old
Number of students in class: 20 students
Xplore Health’s tools used: Orphan drugs Decide Game
Link with different school Higher Biology, Higher Chemistry and PSE curricula
subjects/integration in the curriculum
Pre-knowledge required by students: The research and development cycle of a drug,
acquired by using Xplore Health Virtual experiment
1 - Produce a drug target, Virtual experiment 2 –
Develop a drug!, Game and Video 1 The long and
incredible story of a tablet
Suggested background reading for Xplore Health/ Module 1:
Drug development - 7 – Lesson plans

8. Teacher: How are drugs developed?
Ethical, legal and social aspects
Lesson plan:
Activity Objective of Material Inter- Procedure Time ∑
activity and tools action (min.)
needed
Introduction To explain to Decide T→S Teacher facilitated 5 5
students they Game Ss → discussion about orphan
will be using the Ss drugs to find out the
Decide Game to thoughts of the students
look at the before they start playing
ELSA aspects the Decide Game.
surrounding the
development of
orphan drugs.
Class Activity Students to be Decide T→S Introduction to resource 25 30
split into 5 Game Gw Group discussions
groups of 4 Phase 1 - Ss→
students to Informatio Ss
participate in the n
Decide Game.
Introduction Quick recap for Decide Ss → Student short 10 40
students Game Ss presentations on what
reminding them Phase 3 – they discussed during in
that they are A shared their groups
using the group
Decide Game to response
look at the
ELSA aspects
surrounding the
development of
orphan drugs.
Continuation of
feedback
session.
Class Activity Class to decide Decide Ss → Teacher led class 10 50
on a shared Game Ss discussion
Drug development - 8 – Lesson plans

9. group response Phase 3 –
– can a class A shared
consensus be group
agreed? response
Upload To upload the Decide Ss → Teacher supervised
class class shared Game WWW session allowing students
results to group response Upload to upload class shared
www.play to the website results response to
decide.eu www.playdecide.eu
Lesson plan 4: How is a drug DEVELOPED: the scientific
production of a drug target
General information:
Author of the lesson plan: Laurent MARTORELL
Age level of the students: 16 -18
Xplore Health’s tools used: http://www.xplorehealth.org/en/media/produce-
drug-target
Link with different school subjects/integration The topic fits to my curricula named
in the curriculum: “Biotechnology” where one has to develop what it
takes to make a drug suited to treat a disease
Can the topic be linked to different subjects in
(16 years old student motivated to tackle a
your school? Does it fit to your curricula?
paramedic careers)
Lesson plan:
Activity Objective of Material Inter- Procedure Time ∑
activity and tools action (min.)
needed
The To define what a Classroom Ind or Teacher brings up the 10 10
concept of drug is PC’s with Pw topic on drug to end up
drug internet with the concept of drug:
access an active compound
having a peculiar action
on the body to treat,
prevent an illness.
What is a To assess if the http://www. T Teacher uses the screens 10 20
drug? notion of drug has xplorehealt 1 and 2 of the animation
been correctly h.org/en/m to demonstrate a drug
Drug development - 9 – Lesson plans

10. defined by the edia/produc action is target specific.
student : e-drug- Question: how can one
clarification an target design target specific
explanation by the Interactive drug?
means of blackboard
animation
How to To decline each http://www. Pw / Screen 3: the game gets 20 40
produce a step for a drug xplorehealt Gw started and students are
drug target to be h.org/en/m assigned to play the game
target? developed edia/produc and describe each step of
e-drug- the drug development
target process and what they
Classroom are aimed at.
PC’s with Suggestion: the game to
internet be played full screen but
access this option is not yet
implemented
HOME- To build a http://www. Pw / Recap all the main steps
WORK diagram chart xplorehealt Gw along with their purpose in
presenting all the h.org/en/m a diagram chart
main steps of edia/produc The activity will be
drug e-drug- presented by the
developement target assigned groupwork to all
the classroom
Drug development - 10 – Lesson plans

11. FUNDED BY: PROJECT PARTNERSBY:
WITH THE SUPPORT OF
Drug development - 11 – Lesson plans