Programa del Congreso de Bioquímica y Biología Molecular que se celebra en Sevilla del 4 al

1. Institutions
VIP Sponsors Privileged Sponsors Strategic Sponsors
General Sponsors SEBBM Long Term Sponsors
Exhibitors
September 4th - 9th, 2012
Program
www.iubmb-febs-2012.org
Other Sponsors
Organizers Partner Society

2. La SEBBM contribuye
al progreso de la ciencia
Con un crecimiento continuado neto de 50 socios al año, que se traduce en
Stop by ElSEviEr booth #9 más de 3500 socios actuales, 20 grupos científicos y 1000 inscritos a cada uno
de nuestros congresos, promovemos la sociedad basada en el conocimiento.
We have many interesting and fun events planned for you: Pero no estamos solos...
Meet the Editors and learn what you need to know about publishing your article.
LOS SOCIOS PROTECTORES
Come by during the 10.30 – 11.00 coffee break on: CONTRIBUYEN AL PROGRESO DE LA SEBBM
• September 5: FEBS Letters Editors
• September 6: FEBS Open Bio Editor (new open Access journal)
• September 7 & 8: Molecular Oncology Editor
Get a free goodie bag with lots of interesting material
on how to get published.*
The Editors’ Choice app for iPad and smart phones
presents the top 5 articles, hand-picked by journal editors.
hot oFF thE prESS
Molecular biology
by David Clark, Nanette Pazdernik
iSbN: 9780123785947 / ©2012
Examines the basic concepts of molecular biology while incorporating
primary literature from today’s leading researchers!
20% off at Elsevier booth porque son de los nuestros*
*as long as stock lasts * «Serán socios protectores aquellas entidades que quieran contribuir al
sostenimiento y desarrollo de la SEBBM y sean aceptadas como tales. Tendrán
categoría de socios, podrán participar y votar en las asambleas generales y
recibir la misma información y publicaciones que los socios ordinarios (...)»
www.elsevier.com/lifesciences Más información sobre la figura de socio protector en
Sociedad Española
de Bioquímica y
comunica@sebbm.com o llamando al 93 231 12 00 Biología Molecular

3. WELCOME LETTER
It is both an honor and a pleasure for the Spanish Society of Biochemistry
CONTENTS and Molecular Biology (SEBBM) to organize the 22 nd IUBMB & 37th FEBS
Congress. The standards of modern Spain in Biochemistry and Molecular
Biology are historically high. Attesting to this fact, the SEBBM is a very
1 Welcome Letter active organization encompassing 21 interest groups and more than 4000
2 Committees members. SEBBM, one of FEBS founding societies, has already organized
two successful FEBS meetings (Madrid, 1969, and Barcelona, 1996). And
4 Key Information now Seville, being an ancient, beautiful and welcoming city, home to a very
8 Floor Plan dynamic biochemical community, will host for the very first time this unique
and joint IUBMB-FEBS event.
10 Exhibitors
11 Exhibitor & Poster Area Based on recent spectacular advances in “-omic” disciplines and informa-
tion technology, multidisciplinarity and integration have become key fea-
12 Poster Sessions tures of post-genomic and proteomic research. Genes, gene products, their
regulatory networks and their interactions with their environment must be
13 Satellite Activities
analyzed not only at the molecular level, but also as components of higher-
14 Programs order structures, metabolic pathways or entire cells and organisms. This
branch of research, termed “Systems Biology”, combines concepts in a ho-
14 Social Program and Tours
listic approach from molecular biology, engineering sciences, mathematics
16 Congress Program Overview and information technology to complex biological systems such as living
cells. Hence, close collaboration between biologists, biochemists, physiolo-
18 Plenary Lectures gists, chemists, physicists and mathematicians is essential in order to ex-
20 Congress Detailed Program pand molecular studies into the characterization and modeling of complex
interactions of genes, proteins and metabolic processes.
46 Notes
In line with these advances, an extraordinary scientific program that com-
prehensively covers the latest advances in bioscience research has been
arranged. Multidisciplinarity, interdisciplinarity and transdisciplinarity are
thus essential characteristics of this meeting.
The Organization has worked intensively to make this Congress a most out-
standing experience that lives up to the highest expectations of the par-
ticipant colleagues. We are convinced that this meeting will offer a singular
opportunity for the attendees to engage in fruitful discussions, as well as
establish new friendships and collaborations.
Warm regards,
MIGUEL A. DE LA ROSA
Chair of the Organizing Committee
JOAN J. GUINOVART
Chair of the Scientific Program
IRENE DÍAZ-MORENO
Scientific Secretary
Edition and Production: Rubes Editorial
Printed by Comgrafic
Printed in Spain
1

4. COMMITTEES
Honorary Committee Organizing Committee
Presidency Their Royal Highnesses the Prince Chair Miguel Ángel De la Rosa Spain
and the Princess of Asturias
Secretary Irene Díaz-Moreno Spain
Members President of the Government of Spain
(Spanish Prime Minister) Treasurer Antonio Díaz-Quintana Spain
President of the Andalusian Autonomous Members Andrés Aguilera Spain
Government Catalina Alarcón Spain
Jesús Angulo Spain
Minister of Economy and Competitiveness
Joaquim Ariño Spain
Patricia Boya Spain
Minister of Education, Culture & Sports
Miguel Castanho Portugal
Mayor, City of Sevilla F. Javier Cejudo Spain
Sebastián Chávez Spain
Secretary of State for Research, Development Emilio Fernández-Reyes Spain
and Innovation Antonio Ferrer-Montiel Spain
F. Javier Florencio Spain
Regional Minister of Economy, Innovation José M. García-Fernández Spain
and Science from the Government Miguel García-Guerrero Spain
of Andalusia Carlos Gómez-Moreno Spain
Victoria Guixé Chile
President, Sevilla Provincial Council
Ángel Herráez Spain
Manuel Hervás Spain
President, Spanish National Research
Abdelaziz Hmyene Morocco
Council
Alberto R. Kornblihtt Argentina
President, Universidad de Sevilla Catalina Lara Spain
José López-Barneo Spain
President, Universidad Internacional Luis Mayorga Argentina
de Andalucía Fernando P. Molina-Heredia Spain
Fernando Moreno Spain
President, Universidad Pablo de Olavide Helena Nader Brazil
José Á. Navarro Spain
President, Sevillian Academy of Sciences
Plácido Navas-Lloret Spain
Pedro M. Nieto Spain
President, Cartuja Scientific and
Juan Arturo Olate Aravena Chile
Technological Park
Manuel Pérez Spain
Deputy Master, Royal Cavalry Armory Elizabeth Pintado Spain
of Sevilla Juan Luis Ramos Spain
Luis C. Romero Spain
Joaquim Ros Spain
Enrique de la Rosa Cano Spain
Manuela Rueda Spain
Rafael Salto Spain
Pilar Santistebán Spain
Arantxa Tabernero Spain
Jorge Vázquez Ramos Mexico
José Mª. Vega Spain
Agustín Vioque Spain
2

5. COMMITTEES
Scientific Committee Advisory Committee
Chair Joan Guinovart Spain Members Carlos E. Argaraña Argentina
Jesús Ávila Spain
Members Cecilia Arraiano Portugal Angelo Azzi USA
Dario Alessi UK Jorge Babul Chile
Alicia Alonso Spain M. Luz Cárdenas France
Mariano Barbacid Spain Khalid Fares Morocco
Miguel Beato Spain Debora Foguel Brazil
María A. Blasco Spain Masamitsu Futai Japan
M. Leonor Cancela Portugal Carlos Gancedo Spain
Julio E. Celis Denmark Cristina Garmendia Spain
Ilona I. Concha Grabinger Chile Efstathios Gonos Greece
Daniela Corda Italy Félix Goñi Spain
Frédéric Dardel France Robert Huber, Nobel Laureate Germany
Ana Belén Elgoyhen Argentina Nai-He Jing China
Ernesto Freire USA Karl Kuchler Austria
Ramón Gomis Spain Fernando López-Casillas México
Fotis C. Kafatos UK Carlos Martínez-Alonso Spain
Maria Leptin Germany Iain Mattaj Germany
Carlos López-Otín Spain Phillip Nagley Australia
Federico Mayor Spain Yogeshkumar S. Naik Zimbabwe
M. Teresa Miras-Portugal Spain Uhtaek Oh Korea
Ángela Nieto Spain Glaucius Oliva Brazil
Mary Osborn Germany Sergio Papa Italy
Montserrat Pagés Spain Iqbal Parker South Africa
Richard. N. Perham UK Israel Pecht Israel
Francesc Posas Spain Gregory A. Petsko USA
Catarina Resende de Oliveira Portugal Claudina Rodrigues-Pousada Portugal
Isabel Varela-Nieto Spain Vicente Rubio Spain
William J. Whelan USA Margarita Salas Spain
Felix Wieland Germany Willy Stalmans Belgium
Shi Yigong China Adam Szewczyk Poland
Kenneth N. Timmis Germany
Jia-Rui Wu China
Kurt Wüthrich, Nobel Laureate Switzerland
Bianca Zingales Brazil
3

6. KEY INFORMATION
General Information
Badges Money
The ID badge included in delegate's bags is the admission The official currency in Spain is the Euro ().
pass to the congress venue. Delegates are asked to wear it
all the time. Normal opening hours for banks are Monday to Friday, 08:30 am
- 2:00 pm. There is an ATM service available at FIBES.
Certificate of Attendance
Stores
A Certificate of Attendance will be included in each delegate’s
bag. Opening hours for most large stores in downtown Seville open
Monday to Saturday from 10:00 to 22:00 h.
Internet
First Aid
There will be free Wi-Fi Internet Access up and down FIBES
throughout the congress. In addition, there will be ten fixed A fully equipped first aid room is located at FIBES ground floor.
Internet Access points at the Exhibition Area in Pavilion 3 (see
page 11).
Emergency Numbers (dial toll-free from any phone):
Abstract Book Emergency services  112
Ambulance/Ambulancia  061
The Congress abstract book is published online as FEBS Jour- Fire service/ Bomberos  080
nal Supplement (Wiley-Blackwell). National Police/Policía Nacional  091
(in case of serious crime)
A full abstract search for author, key words or titles is also Local Police/Policía Municipal  092
available from the congress website. (for towns and cities)
Civil Guard/Guardia Civil  062
(for small towns and villages)
Language
English is the Congress official language. No translation will Refreshments and Catering
be provided.
Lunch boxes will be available to all registered participants on
September 5, 6 and 8, at 13:00 h, at Pavilion 3 (see page 11).
Registration Desk Opening Hours
The registration desk under the dome will be open on:
Contacts
Tuesday, September 4 12:00 – 20:00 h
Wednesday, September 5 08:00 – 19:00 h Scientific Secretariat
Thursday, September 6 08:00 – 19:00 h Dr. Irene Díaz-Moreno
Friday, September 7 08:00 – 13:00 h IBVF, Universidad de Sevilla-CSIC, CIC Isla de la Cartuja
Saturday, September 8 08:00 – 19:00 h Américo Vespucio, 49. 41092-Seville (Spain)
Sunday, September 9 08:00 – 12:00 h Phone: +34 954 489 513 - Fax: +34 954 460 065
E-mail: scientificsecretariat@iubmb-febs-2012.org
Speakers’ Corner
Technical Secretariat
Viajes El Corte Inglés
Invited speakers will be available for informal discussion and
División de Congresos
debate at a predefined meeting room. The speakers available
Teniente Borges, 5. 41002-Seville (Spain)
will rotate according to the list of speakers of the day. Every-
Phone: +34 954 506 605 - Fax: +34 954 225 949
body is welcome!
E-mail: technicalsecretariat@iubmb-febs-2012.org
Sponsoring Contact
Imma Rullo
Girona, 36. 08010-Barcelona (Spain)
E-mail: sponsors@iubmb-febs-2012.org
4

7. 5

8. KEY INFORMATION
Congress Venue How to reach FIBES
The Congress is held at the Seville Conference and Exhibi- Transport
tion Centre (FIBES), close to the city's international airport.
The Commuter Train C4 runs every 6 minutes all day long
FIBES is strategically situated at 4 km from Seville´s interna- from Santa Justa Station to Palacio de Congresos (FIBES). A
tional airport, 5 km from Santa Justa Train Station, and 7 km round-trip ticket costs only  2.10 ( 1.40 one way).
from the city center. A taxi ride takes 10 min to the airport
( 20-25), 15 min to the train station ( 6-8), and 20 min to The bus line 27 runs very frequently as well, especially during
downtown ( 8-10). rush hours, from and to the Meeting Venue (FIBES). You can
buy the ticket on board for  1.30.
Visit the section How to reach FIBES (Venue) at http://
www.iubmb-febs-2012.org/IUBMBFEBS2012/index.
asp?item=2221 to see train and bus timetables.
Airport
FIBES
Plaza
Santa Justa
Duque
Train Station
Taxis
Taxis are all around the city, and are white with a diagonal yel-
lowish stripe on the side back door. A taxi fare to the airport
should cost approximately  20-25.
Car Parking
There is a parking lot at the congress venue.
Plan
Seville Convention Center (FIBES)
Avda Alcalde Luis Uruñuela, 1
6 Sevilla

9. Life Science Research
The future of qPCR is here
and it’s digital
y
That’s ddPCRevolutionary.
Bio-Rad’s QX100™ Droplet Digital™ PCR system provides an absolute measure of target DNA
molecules with unrivalled precision and accuracy. The QX100 system partitions each sample into
20,000 individual nanolitre-sized droplets. PCR-positive and PCR-negative droplets from every
sample are then counted to provide absolute target quantification in digital form. The QX100 system
provides a revolutionary approach to target DNA quantification.
viral research.
(down to 1.2x differences).
a standard curve or ΔΔCq.
7
To find your local sales office, visit
www.bio-rad.com/contact/ Visit us on the Web at discover.bio-rad.com

10. FLOOR PLAN
Ground Floor
First Floor
8

11. IUBMB & FEBS Congress,
Sevilla 2012, booth 17 /18 / 19
The 360° Evolution
Eppendorf Combitips advanced®
The high demands of modern lab work > Ergonomic design
have also heightened the requirements > Individually color coded
for a high-precision dispensing tip. > Elongated tips (2.5 / 5 / 10 mL)
Our experts thoroughly optimized the > Optimized graduations
Combtips using sophisticated engineering. >
The result: A completely new standard see online
in dispensing tips.
9
www.eppendorf.com/combitips-advanced
eppendorf® and Combitips advanced® are registered trademarks of Eppendorf AG.
All rights reserved, including images and graphics. Copyright © 2012 by Eppendorf AG.

12. EXHIBITORS
Booths No.
ACS Publications 1
Agilent Technologies 31
American Association for the Advancement of Science (AAAS) 47-48
American Society for Biochemistry and Molecular Biology (ASBMB) 3
Biochemical Society 24
Bioline 7
Bio-Rad 26-27-28
Bruker Española S.A. 42-43-44
Cayman Chemical 14
Cell Signaling Technology & New England BioLabs (CST) 39
Cellectis bioresearch 25
cicCartuja (Scientific Research Center Isla de la Cartuja) 12
De Gruyter 11
Research in Germany – German Research Foundation (DFG) 5
ELGA LabWater 30
eLife 41
Elsevier 9
Eppendorf 17-18-19
European Molecular Biology Laboratory (EMBL) 49
European Molecular Biology Organization (EMBO) 50
European Research Council (ERC) 36
Federation of European Biochemical Societies (FEBS) 21
Human Frontier Science Program (HFSP) 8
International Union of Biochemistry and Molecular Biology (IUBMB) 34
Laboratorios Conda 4
Merck Millipore 2
Novusbio 38
Panreac 32
Portuguese Biochemical Society (SPB) 23
Progenika Biopharma S.A. 29
Royal Society 6
Sarstedt 10
Sigma 33
Sistemas Genómicos 40
Sociedad Española de Bioquímica y Biología Molecular (SEBBM) 22
Sociedade Brasileira de Bioquímica e Biologia Molecular (SBBq) 35
Springer 15-16
St. Jude Children’s Research Hospital 45
Takara Bio Europe 13
The Crystalization Factory 37
Tocris Bioscience 46
Vitro, S.A. 20
Wiley-Blackwell 53-54
Wisepress Medical Bookshop 59
10

13. EXHIBITOR & POSTER AREA
Pavilion 3
56
55 57
CATERING
35
34
4
CATERING CATERING
33
3
CHILD
CARE
SERVICE
VIC
30
29
CATERING CATERING
MEETING POINT
ER S’
RN ER
CO AK
E
SP
26 INTERNET
POINT
25
5
CATERING CATERING
59
Access to the Congress Area
(Auditorium, Rooms, Registration Desk) 11

14. POSTER SESSIONS
Poster Discussion Sessions 5 September 2012
05. Biomembranes & Bioenergetics 15. Molecular Parasitology
Posters will be presented by the authors
08. Free Radicals & Oxidative Stress 18. Nutritional Biochemistry
and displayed at the Exhibitor Area.
11. Membrane Transporters 20. Protein Structure & Function
Three sessions will take place throug-
hout the Congress, as shown in the ta- 14. Molecular Biotechnology 26. Transgenesis in Mammals
ble on the right. 6 September 2012
01. Apoptosis 16. Neuroscience
Please note that presenters are respon-
02. Biochemical Education 17. Nitrogen Biochemistry & Metabolism
sible for putting up the posters on the
06. Cell signaling 19. Perinatal Biochemistry
corresponding board before each session,
and removing them at the end of the 07. Developmental Biology 21. Regulation of Gene Expresssion
day (not later than 20:00 h). 09. Genomics & Proteomics & Genome Dynamics
12. Metabolic Regulation 25. Theoretical Molecular Biology
The maximum size of poster boards is 8 September 2012
120 cm (length) × 90 cm (width).
03. Biochemistry and Molecular 13. Molecular Bases of Pathology
Biology of Plants 22. RNA Biology
The poster numbers will be displayed
on the poster boards, abstract book and 04. Biochemistry in Medical Diagnosis 23. Single Molecules
each poster presenter’s private area on & Therapy 24. Systems Biology
the congress website. 10. Glycobiology 27. Others
12

15. SATELLITE ACTIVITIES
Biochemistry in the City Specific Activities
A number of parallel events open to the general public The specific activities aim to promote discussion amongst
have been organized to coincide with the international delegates, corporate partners, and exhibitors.
congress. Their aim is to bring Biochemistry closer to peo-
ple by explaining its impact on various facets of society, Corporate Seminars
and to inspire the biochemists of tomorrow. Corporate partners will be able to present new products,
share information with delegates, and receive feedback.
Lectures Open to the Public See Detailed Program (pages 20-45).
This activity includes two lectures open to the general pu-
blic interested in the following issues:
Guided Poster Tour
Functional Diet - Health and Aging Attendees wishing to participate will be divided in small
Francisco García Olmedo. Universidad Politécnica de groups, maximum 10 people. Each group will visit their
Madrid, Madrid, ES posters guided by an Invited Speaker. These guided poster
Daniel Ramón. Prof. de Investigación del CSIC Valencia, tours aim to:
Valencia, ES
September 6 – 20:00 h 1. increase the visibility of the posters,
Location: Centro Cultural Cajasol. Sala Juan de Mairena. 2. facilitate the exchange between speakers and poster
Calle Laraña 4. Sevilla presenters, and
(Maximum capacity: 100 people) 3. promote scientific discussions during poster sessions.
Cancer - New Approach & Therapies This voluntary activity required the registration of inter-
Carlos López-Otín. Oviedo University, Oviedo, ES ested congress attendees during the online registration
Joan Massagué. Sloan-Kettering Institute, New York, US process.
September 7 – 20:00 h
Location: Real Maestranza de Caballería. Salón de Carte-
les. Paseo Colón 12. Sevilla Speakers’ Corner
(Maximum capacity: 100 people) Invited speakers will be available for informal discussion
and debate at a predefined meeting room. The speakers
available will rotate according to the list of speakers of the
"And You? Me, a Biochemist!" day. Everybody is welcome!
Twenty five of the best high school students from the pro-
vince of Seville will be invited to participate in a three day
course aimed to provide a general outlook of Biochemistry Portrait Gallery
as a career path. The course will consist of three parts: The Portrait Gallery aims to honour 24 outstanding female
scientists who played crucial roles in the development of
1. A lecture at the Faculty of Biology on how to achieve Biochemistry worldwide. Each woman will have her own
a Biochemistry degree at the University of Seville exhibition panel with her photo and biography both in
and on the subsequent career possibilities. English and in Spanish.
2. A visit to the congress venue, the Seville Conference
and Exhibition Centre FIBES, to get to know how an
international congress looks like. There, the students Women Career Lunch
will receive lectures by Spanish invited Speakers. This informal lunch with outstanding female scientists will
3. A short, hands-on training course on DNA extrac- allow young participants to discuss difficulties they may
tion so these students can participate actively in the find during their career development and talk about alter-
“Genes in the Bottle” sessions (see below). native solutions. The sign-up sheet will be available at the
FEBS stand (booth: 21), and only the first 60 registrants
The students will receive a certificate of their participation will be able to attend. This activity will take place at the
by the University of Seville at the end of the course. Congress venue on Saturday, September 8, from 13:00
to 15:00, so everybody has time to go to the subsequent
Women in Biochemistry Workshop starting at 15:30.
Genes in the Bottle
The general public from the streets of Seville will be
invited to participate in this activity. They will learn the
basic process to isolate their own DNA and find out some
of the fascinating aspects of these molecules.
13

16. SOCIAL PROGRAM AND TOURS
Social Program
Social Events
Welcome Reception Congress Dinner
Tuesday, 4 September Saturday, 8 September
20:00 - 21:30 h 21:00 - 22:30 h
Conference and Exhibition Centre - FIBES Square Previous registration ( 70).
Tours
Event Tuersday Wednesday Friday Thursday Saturday
Sept. 4 Sept. 5 Sept. 6 Sept. 7 Sept.8
WALKING TOUR OF SEVILLE     
Starting time: 10:00 am (2 hours) (morning) (morning) (morning) (morning) (morning)
Meeting point: Virgen de los Reyes Square, behind the Cathedral
SEVILLIAN TAPAS TOUR     
Starting time: 10:30 pm (2 hours) (night) (night) (night) (night) (night)
Meeting point: Virgen de los Reyes Square, behind the Cathedral
FLAMENCO SHOW & DINNER     
Starting time: 07:00 pm or 09:30 pm (1h 30 min aprox) (evening) (evening) (evening) (evening) (evening)
Meeting point: Main entrance of the Palacio Andaluz
SEVILLE ON BIKE     
Starting time: 10:30 am – 02:00 pm (aprox) (morning) (morning) (morning) (morning) (morning)
Meeting point: NH Plaza de Armas Hotel - Main door
VISIT TO ITALICA AND CARMONA     
Starting time: 08:00 am (half-day) (half-day) (half-day) (half-day) (half-day)
Meeting point: Conference and Exhibition Center - FIBES Center
VISIT TO WINE CELLAR     
Starting time: 10:00 am (half-day) (half-day) (half-day) (half-day) (half-day)
Meeting point: Conference and Exhibition Center - FIBES Center
DAY TRIP TO CORDOBA     
Starting time: 08:30 am (lunch NOT included)
Meeting point: Conference and Exhibition Center - FIBES Center
DAY TRIP TO JEREZ   
Starting time: 08:30 am (lunch NOT included) (Equestrian shows only on Saturday)
Meeting point: Conference and Exhibition Center - FIBES Center
14

17. SOCIAL PROGRAM AND TOURS
Event Tuersday Wednesday Friday Thursday Saturday
Sept. 4 Sept. 5 Sept. 6 Sept. 7 Sept.8
DAY TRIP TO CADIZ     
Starting time: 08:30 am (lunch NOT included)
Meeting point: Conference and Exhibition Center - FIBES Center
2 DAYS TRIP TO RONDA AND MALAGA  
Starting time: 08:00 am (meals NOT included)
Meeting point: Conference and Exhibition Center - FIBES Center
2 DAYS TRIP TO GRANADA   
Starting time: 08:30 am (meals NOT included)
Meeting point: Conference and Exhibition Center - FIBES Center
15

18. CONGRESS PROGRAM OVERVIEW
Tuesday, September 4th Wednesday, September 5th Thursday, September 6th
8:30 8:30
S01 Single Molecules
8
8:30
01.1 Protein-Nucleic Acid Interactions S01 Single Molecules
01.2 Protein Networks
9 9 S02 Trends in Biochemistry
02.1 Genome Dynamics
9
S02 Trends in Biochemistry
02.2 Transcription and Chromatin
S03 Beyond Biochemistry
S03 Beyond Biochemistry
9:30 9:30 03.1 Ageing
S04 Molecular Bases of Diseases
9
9:30 03.2 Global Regulation and Cell Reprogramming
04.1 Neurodegenerative and Organ S04 Molecular Bases of Diseases
04.2 Inflammation and Diseases
10 10 Degenerative Diseases
S05 Environmental Biochemistry
1
10
S05 Environmental Biochemistry
05.1 Oxidative Stress: Dealing with Oxygen 05.2 Dealing with Osmotic Stress
10:30 10:30 10:30
10
11 11 11
1
11:30 11:30 PL03 Osamu Hayaishi 11:30
11 PL07 IUBMB Life
12 12 12
1
12:30 12:30 PL04 Theodor Bucher 12:30
12 PL08 FEBS Journals Awards
13 13 13
1
13:30 13:30 13:30
13
14 14 14
1
14:30 14:30 Poster Sessions & Specific Activities 14:30
14 Poster Sessions & Specific Activities
BE
15 15 15
1
15:30 15:30
W01 Functional Genomics
15:30
15
W02 Proteomics and Signal Transduction
W04 Biochemistry in Medical Diagnosis W05 Forum for Bioentrepreneurs
16 16
and Therapy
16
1
W08 Malaria in the Developing World
W07 AIDS: Perspectives and New Therapies
16:30 16:30
W10 Teaching Molecular Evolution:
16:30
16 W11 Research into Effective Teaching
Strategies: What Biochemistry
BE a Unifying Principle of Biochemistry BE
Is Learning from Other Sciences
17 17
1 17
1
17:30 Opening Session 17:30
17 PL05 Chester Beatty 17:30
17 PL09 EMBO
18 18
1 18
1
PL01 IUBMB PL06 Prakash S. Datta SEBBM01
18:30 18:30
18 18:30
18
Hermann Niemeyer
19 19
1 19
1
19:30 PL02 FEBS 19:30
19 19:30
19
SEBBM Groups
20 20
2 20
2
SEBBM
Spanish-Mexican Groups
20:30 20:30
20 Symposium 20:30
20
Reception
21 21
2 21
2
21:30 21:30
21 21:30
21
22 22 22
16 22:30 22:30 22:30

19. Friday, September 7th Saturday, September 8th Sunday, September 9th
S01 Single Molecules
8
8:30 8
8:30
S01 Single Molecules
8
8:30
01.3 Membranes and Proteins S01 Single Molecules 01.5 Engineering and Design
01.4 Intrinsically Disordered Proteins
S02 Trends in Biochemistry
02.3 RNA Biogenesis and Processing
9
S02 Trends in Biochemistry 9 S02 Trends in Biochemistry
02.5 Integrated Cell Structure and Function
9
02.4 Autophagy and Protein Homeostasis
S03 Beyond Biochemistry S03 Beyond Biochemistry S03 Beyond Biochemistry
03.3 Artificial Cells and Genomes
S04 Molecular Bases of Diseases
9
9:30 03.4 Computing with Molecules and Cells 9:30
9 03.5 Dealing with Errors and Evolution
S04 Molecular Bases of Diseases
9:30
9
04.3 Stem Cells and their Niches S04 Molecular Bases of Diseases 04.5 Role of Hypoxia in Pathogenesis of
04.4 Cancer Genomics and Biomarkers
S05 Environmental Biochemistry
05.3 Life in Extreme Environments
1
10
S05 Environmental Biochemistry
10
1 Inflammation in Cancer
S05 Environmental Biochemistry
10
1
(In memoriam of Costas Drainas) 05.4 Responding to Environmental Perception 05.5 Molecular Clocks and Cell Cycling
10:30
10 10:30
10
BE
10:30
1
11
1 11
1 PL15 Edward Wood 11
1
PL10 FEBS/EMBO
Women in Science Award
11:30
11 PL12 Severo Ochoa 11:30
11 11:30
1
12
1 12
1 PL16 Sir Hans Krebs 12
1
PL11 Alberto Sols-Fundación BBVA 12:30
12 PL13 PABMB-Fundación Ramón Areces 12:30
12 12:30
1
Closing Session
13
1 13
1 13
1
13:30
13 13:30
13 13:30
14
1 14
1 14
14:30
14 Poster Sessions & Specific Activities 14:30
14 14:30
15
1 15
1 15
15:30
15 15:30
15 15:30
W03 Metabolomics
16
1
W06 Systems Biology
16
1 16
W09 Science in School BE
NMR in Biology 16:30
16 16:30
16 16:30
W12 Women in Biochemistry: from Past to F
ast Future
17
1 17
1 17
17:30
17 PL14 Edward C. Slater 17:30
17 17:30
18
1 18
1 18
SEBBM02
18:30
18
Luis Federico Leloir 18:30
18 18:30
19
1 19
1 19
19:30
19 SEBBM Prizes 19:30
19 19:30
20
2 20
2 20
20:30 20:30 20:30
21 21
2 21
21:30 21:30
21 21:30
Congress Dinner
22 22
2
BE : Biochemical 22
Education
22:30 22:30
22 activities 22:30 17

20. PLENARY LECTURES
Tuesday, September 4, 2012
17:30 – 17:45 PL00 Opening Lecture
Auditorium The ERC - funding frontier research in times of austerity
Helga Nowotny (Vienna, AT)
18:00 – 19:00 PL01 IUBMB
Auditorium Chair: Carlos Gancedo (Madrid, ES). Laudator: Angelo Azzi (Boston, MA, US)
Switches and latches: the control of entry into mitosis
Tim Hunt (Hertfordshire, UK)
19:00 – 20:00 PL02 FEBS
Auditorium Chair: Sergio Papa (Bari, IT). Laudator: Jaak Järv (Tallinn, EE)
Towards a comprehensive description of the proteome by high resolution mass spectrometry
Mathias Mann (Martinsried, DE)
Wednesday, September 5, 2012
11:00 – 12:00 PL03 Osamu Hayaishi
Auditorium Chair: Miguel G. Guerrero (Sevilla, ES). Laudator: Greg Petsko (Boston, MA, US)
Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development
Ferid Murad (Washington, DC, US)
12:00 – 13:00 PL04 Theodor Bucher
Auditorium Chair: Vito Turk (Ljubljana, SI). Laudator: Israel Pecht (Rehovot, IL)
Fuzziness of globular and aggregating proteins in neurodegeneration: an NMR spectroscopic view
Christian Griesinger (Göttingen, DE)
17:00 – 18:00 PL05 Chester Beatty
Auditorium Chair: José M. Vega (Sevilla, ES). Laudator: Stahis Gonos (Athens, GR)
Protein quality control by the unfolded protein response
Kazutoshi Mori (Kyoto, JP)
18:00 – 19:00 PL06 Prakash S. Datta
Auditorium Chair: José M. Mato (Bilbao, ES). Laudator: Adam Szewczyk (Warsaw, PL)
Life: expectancies & origins
Ada Yonath (Rehovot, IL)
Thursday, September 6, 2012
11:00 – 12:00 PL07 IUBMB Life
Auditorium Chair: Fernando Moreno (Oviedo, ES). Laudator: Iqbal Parker (Cape Town, ZA)
Targeted therapy: the new lease on life for leukemia
Sai-Juan Chen (Shanghai, CN)
12:00 – 12:30 PL08-1 FEBS Letters Award
Auditorium Chair: Laszlo Fésüs (Debrecen, HU). Laudator: Felix Wieland (Heidelberg, DE)
Oncogenic signaling pathway induced by myeloproliferative neoplasm-associated JAK2 V617F
mutant
Megumi Funakoshi-Tago (Tokyo, JP)
18

21. PLENARY LECTURES
12:30 – 13:00 PL08-2 FEBS Journal Award
Auditorium Chair: Laszlo Fésüs (Debrecen, HU). Laudator: Richard Perham (Cambridge, UK)
Insulin receptor substrate 2 and FoxO3a signalling are involved in E-cadherin expression
and transforming growth factor-1-induced repression in kidney epithelial cells
Rosemarie M. Carew (Dublin, IE)
17:00 – 18:00 PL09 EMBO
Auditorium Chair: Margarita Salas (Madrid, ES). Laudator: Claudina Rodrigues-Pousada (Lisboa, PT)
An expanding job description for the master transcriptional regulator Blimp1/Prdm1 during
mammalian development
Elizabeth Robertson (Oxford, UK)
Friday, September 7, 2012
11:00 – 12:00 PL10 FEBS/EMBO Women in Science Award
Auditorium Chair: Lea Sistonen (Turku, FI). Laudator: Erich Nigg (Basel, CH)
The dance of DNA: chromatin dynamics during DNA repair
Susan M. Gasser (Basel, CH)
12:00 – 13:00 PL11 Alberto Sols-Fundación BBVA
Auditorium Chair: Federico Mayor-Menéndez (Madrid, ES). Laudator: Miguel A. De la Rosa (Sevilla, ES)
Exploring the cancer and aging hallmarks: from genes to genomes
Carlos López-Otín (Oviedo, ES)
Saturday, September 8, 2012
11:00 – 12:00 PL12 Severo Ochoa
Auditorium Chair: Jacques-Henry Weil (Strasbourg, FR). Laudator: Willy Stalmans (Leuven, BE)
Mechanisms of cellular proteostasis: insights from single molecule approaches
Carlos Bustamante (Berkeley, CA, US)
12:00 – 13:00 PL13 PABMB-Fundación Ramón Areces
Auditorium Chair: Jorge Babul (Santiago, CL). Laudator: Joan J. Guinovart (Barcelona, ES)
TGF- signaling in stem cells and cancer
Joan Massagué (New York, NY, US)
17:00 – 18:00 PL14 Edward C. Slater
Auditorium Chair: Irene Díaz-Moreno (Sevilla, ES). Laudator: Michael Walsh (Calgary, CA)
Intracellular protease machines, structures, mechanisms and drug development
Robert Huber (Martinsried, DE)
Sunday, September 9, 2012
10:30 – 11:30 BE PL15 Edward Wood
Auditorium Chair: Miguel Castanho (Lisboa, PT). Laudator: Susan Hamilton (Brisbane, AU)
Biology past and biology future: where have we been and where are we going?
Bruce Alberts (San Francisco, CA, US)
11:30 – 12:30 PL16 Sir Hans Krebs
Auditorium Chair: Vicente Rubio (Valencia, ES). Laudator: Alan Fersht (Cambridge, UK)
Decoding of mRNA and quality control by the ribosome
Venki Ramakrishnan (Cambridge, UK)
19

22. CONGRESS DETAILED PROGRAM
Tuesday, September 4, 2012
17:00 – 18:00 Opening Session
Auditorium Angelo Azzi (Boston, MA, US) - IUBMB, President
Israel Pecht (Rehovot, IL) - FEBS, General Secretary
Miguel A. De la Rosa (Seville, ES) - IUBMB-FEBS-2012 Congress, Chair
Helga Nowotny (Vienna, AT) - ERC, President
FEBS General Secretary, Israel Pecht, will award FEBS Diplome d'honneur to Federico Mayor-Zaragoza
IUBMB President, Angelo Azzi, will award the IUBMB Medal to Santiago Grisolía
18:00 – 19:00 PL01 IUBMB
Auditorium Chair: Carlos Gancedo (Madrid, ES). Laudator: Angelo Azzi (Boston, MA, US)
Switches and latches: the control of entry into mitosis
Tim Hunt (Hertfordshire, UK)
19:00 – 20:00 PL02 FEBS
Auditorium Chair: Sergio Papa (Bari, IT). Laudator: Jaak Järv (Tallinn, EE)
Towards a comprehensive description of the proteome by high resolution mass spectrometry
Mathias Mann (Martinsried, DE)
20:00 – 21:30 Reception
FIBES Square
Wednesday, September 5, 2012
08:30 – 10:25 S01 Single Molecules
Auditorium 01.1 Protein-Nucleic Acid Interactions
Chairs: Jackie Wilce (Melbourne, AU) and Guillermo Montoya (Madrid, ES)
08:30 – 08:55 S01.1-1 Unusual modes of RNA recognitions by RNA recognition motifs
Frederic Allain (Zürich, CH)
09:00 – 09:25 S01.1-2 RNA chaperones modulate RNA structural dynamics through energy transfer
Renée Schroeder (Vienna, AT)
09:30 – 09:55 S01.1-3 Structural studies on ribonucleoprotein complexes
Alfredo Torres-Larios (Mexico DF, MX)
10:00 – 10:25 S01.1-4 DNA lesion recognition and mismatch repair
Wei Yang (Bethesda, MD, US)
08:30 – 10:25 S02 Trends in Biochemistry
Room F 02.1 Genome Dynamics
Chairs: Camilla Sjögren (Stockholm, SW) and Andrés Aguilera (Sevilla, ES)
08:30 – 08:55 S02.1-1 R-loops in recombination-mediated genome instability
Andrés Aguilera (Seville, ES)
09:00 – 09:25 S02.1-2 Control over DNA replication in time and space
Zoi Lygerou (Patras, GR)
20

23. CONGRESS DETAILED PROGRAM
09:30 – 09:55 S02.1-3 Genomic studies in African populations: approaches and applications
Michele Ramsay (Johannesburg, ZA)
10:00 – 10:25 S02.1-4 DNA topology and SMC complexes in chromosome structure and stability
Camilla Sjögren (Stockholm, SE)
08:30 – 10:25 S03 Beyond Biochemistry
Room B 03.1 Ageing
Chairs: David Sinclair (Boston, MA, US) and Manuel Guzmán (Madrid, ES)
08:30 – 08:55 S03.1-1 Telomerase gene therapy delays aging and increases longevity in adult and old mice
Maria Blasco (Madrid, ES)
09:00 – 09:25 S03.1-2 Proteasome activation as a novel anti-aging strategy
Stathis Gonos (Athens, GR)
09:30 – 09:55 S03.1-3 Molecular mechanisms underlying genotype-dependent responses to dietary restriction
Matt Kaeberlein (Seattle, WA, US)
10:00 – 10:25 S03.1-4 Activating conserved longevity pathways: from yeast to humans
David Sinclair (Boston, MA, US)
08:30 – 10:25 S04 Molecular Bases of Diseases
Room A 04.1 Neurodegenerative and Organ Degenerative Diseases
Chairs: Dario Alessi (Dundee, UK) and Arantxa Tabernero (Salamanca, ES)
08:30 – 08:55 S04.1-1 Disruptions on the highways of cellular signaling
Dario Alessi (Dundee, UK)
09:00 – 09:25 S04.1-2 From aminoacyl-tRNA synthetase mutations to peripheral neuropathies - a flying perspective
Albena Jordanova (Antwerp, BE)
09:30 – 09:55 S04.1-3 The reactivation of the epithelial-mesenchymal transition in organ degeneration
M. Angela Nieto (San Juan de Alicante, ES)
10:00 – 10:25 S04.1-4 Clearance of misfolded proteins in systemic amyloidosis: experience with transthyretin
Maria João Saraiva (Porto, PT)
08:30 – 10:25 S05 Environmental Biochemistry
Room C 05.1 Oxidative Stress: Dealing with Oxygen
Chairs: Alicia Juliana Kowaltowski (São Paulo, BR) and Marta Cascante (Barcelona, ES)
08:30 – 08:55 S05.1-1 Protection of the photosynthetic apparatus against oxygen stress
Eva-Mari Aro (Turku, FI)
09:00 – 09:25 Portuguese-Brazilian Conference
S05.1-2 Dietary interventions, mitochondria, oxidants and lifespan
Alicia Kowaltowski (São Paulo, BR)
09:30 – 09:55 S05.1-3 Oxidative stress, antioxidants and apoptosis: impact on cancer therapy
Tomris Özben (Antalya, TR)
10:00 – 10:25 S05.1-4 Control of adrenal steroidogenesis via H2O2-dependent, reversible inactivation
of peroxiredoxin III in mitochondria
Sue Goo Rhee (Seoul, KR)
10:30 – 11:00 Break
21

24. CONGRESS DETAILED PROGRAM
11:00 – 12:00 PL03 Osamu Hayaishi
Auditorium Chair: Miguel G. Guerrero (Sevilla, ES). Laudator: Greg Petsko (Boston, MA, US)
Discovery of nitric oxide and cyclic GMP in cell signaling and their role in drug development
Ferid Murad (Washington, DC, US)
12:00 – 13:00 PL04 Theodor Bucher
Auditorium Chair: Vito Turk (Ljubljana, SI). Laudator: Israel Pecht (Rehovot, IL)
Fuzziness of globular and aggregating proteins in neurodegeneration: an NMR spectroscopic view
Christian Griesinger (Göttingen, DE)
13:00-13:30 Pause
13:15 – 15:30 R15 Perinatal Biochemistry
Room G Chairs: Pilar Ramos (Madrid, ES) and Anna Gumà (Barcelona, ES)
(lunch boxes will be available at Room G from 13:00 h exclusively for this session attendees)
13:15 – 13:45 P19-5 Mitochondrial metabolism and hormone action is regulated by proteins participating
in mitochondrial dynamics
Antonio Zorzano (Barcelona, ES)
Selected Communications (15 min each)
13:45 – 14:05 P12-26 Increased fatty acid oxidation protects adipocytes from lipid-induced insulin resistance
Laura Herrero (Barcelona, ES)
14:05 – 14:20 P12m-41 Lipoprotein lipase during postnatal development in the rat: activity and pI isoforms
Pere Carulla (Barcelona, ES)
14:20 – 14:35 P19-3 Gestational diabetes and obesity: role of oxidative stress and inflammation
M. Pilar Ramos Alvarez (Madrid, ES)
14:35 – 14:50 P19r-2 Monitoring pregnancy and prenatal disorders through NMR metabolic profiling
of maternal blood plasma
Joana Pinto (Aveiro, PT)
13:30-15:30 Poster Sessions
Exhibitor Area P05 Biomembranes & Bioenergetics – P08 Free Radicals & Oxidative Stress – P11 Membrane
Transporters – P14 Molecular Biotechnology – P15 Molecular Parasitology – P18 Nutritional
Biochemistry – P20 Protein Structure & Function – P26 Transgenesis in Mammals
13:30-15:30 ESHGE Seminar: How can we assure the quality of genetic testing
Room A (European Society of Human Genetics and Eurogentest)
Overview of activities of the European Society of Human Genetics
Milan Macek (Prague, CZ)
Direct to consumer genetic testing
Cecile Janssens (Rotterdam, NL)
Accreditation in genetic testing
Michael Morris (Geneva, CH)
Next generation sequencing in clinical practice
Gert Matthijs (Leuven, BE)
22

25. CONGRESS DETAILED PROGRAM
13:30-15:30 DFG Workshop: Steps towards a successful scientific career
Room B (Research in Germany – German Research Foundation, DFG)
A road to scientific independence
Anne-Kathrin Classen (Munich, DE)
Research and funding at German universities and non-university research institutions: a reviewer’s
and grantee’s perspective
Christian Griesinger (Göttingen, DE)
Reasons for pursuing research in Germany: A US returnee‘s point of view
Caroline Kisker (Würzburg, DE)
Funding programmes supporting your research career
Andreas Strecker (Bonn, DE)
15:30 – 16:55 W01 Functional Genomics
Auditorium Chairs: Thomas Gingeras (Cold Spring Harbor, NY, US) and Francisco Cánovas (Málaga, ES)
15:30 – 15:55 W01-1 Important lessons from complex genomes
Thomas Gingeras (Cold Spring Harbor, NY, US)
16:00 – 16:25 W01-2 Nitrogen regulatory networks controlling plant root growth
Rodrigo Gutiérrez (Santiago, CL)
16:30 – 16:55 W01-3 Genomics and the “Century of Biology”
Huanming Yang (Beijing, CN)
15:30 – 16:55 W04 Biochemistry in Medical Diagnosis and Therapy
Room A Chairs: Axel Ullrich (Martinsried, DE) and Elizabeth Pintado (Sevilla, ES)
15:30 – 15:55 W04r-1 Developing new tools for cancer diagnostics and therapeutics: fluorescent peptide
biosensors of cyclin-dependent kinases
May C. Morris (Montpellier, FR)
16:00 – 16:25 W04-2 Fragile X syndrome and FMR1 associated disorders
Flora Tassone (Davis, CA, US)
16:30 – 16:55 W04-3 From discovery to targeted drug development
Axel Ullrich (Martinsried, DE)
15:30 – 16:55 W07 AIDS: Perspectives and New Therapies
Room F Chair: Joan Guinovart (Barcelona, ES) and Jacques-Henry Weil (Strasbourg, FR)
15:30 – 16:10 W07-1 HIV-Host interactions: research challenges and future directions
José Alcami (Madrid, ES)
16:15 – 16:55 W07-2 From AIDS to HIV chronic infection: scientific advances, society mobilisation and public Health
France Lert (Villejuif, FR)
15:30 – 16:55 BE W10 Teaching Molecular Evolution: a Unifying Principle of Biochemistry
Room B Chairs: Keith Elliott (Manchester, UK) and Athel Cornish-Bowden (Marseille, FR)
15:30 – 15:55 W10-1 Teaching on the emergence of biochemical functions
Juli Peretó (Valencia, ES)
16:00 – 16:25 W10-2 Evolving molecules, viroids and viruses - Theory, models and reality
Peter Schuster (Vienna, AT)
16:30 – 16:55 Discussion
23

26. CONGRESS DETAILED PROGRAM
16:00 – 17:30 ERC Seminar
Room C (European Research Council)
The European Research Council, a great funding opportunity
Speaker: Dr. Nicolas Voilley, ERC
17:00 – 18:00 PL05 Chester Beatty
Auditorium Chair: José M. Vega (Sevilla, ES). Laudator: Stahis Gonos (Athens, GR)
Protein quality control by the unfolded protein response
Kazutoshi Mori (Kyoto, JP)
18:00 – 19:00 PL06 Prakash S. Datta
Auditorium Chair: José M. Mato (Bilbao, ES). Laudator: Adam Szewczyk (Warsaw, PL)
Life: expectancies & origins
Ada Yonath (Rehovot, IL)
19:00 – 21:30 Spanish-Mexican Symposium
Room C Chairs: Montserrat Pagès (Barcelona, ES) and Alfredo Herrera Estrella (Guanajuato, MX)
19:00 – 19:30 SEBBM SHM-1 Betaglycan involvement in brain development
Fernando López-Casillas (México DF, MX)
19:35 – 20:05 SEBBM SHM-2 Trichoderma sensing the environment for survival and dispersal
Alfredo Herrera Estrella (Guanajuato, MX)
20:10 – 20:40 SEBBM SHM-3 Seasonal control of storage organ formation: new varieties tolerant to heat-stress
Salomé Prat (Madrid, ES)
20:45 – 21:15 SEBBM SHM-4 Study of the pathogenesis of sirenomelia in a novel animal model
Marian Ros (Santander, ES)
19:00 – 21:30 R02 Biochemistry and Molecular Biology of Plants
Room D Chair: Mariam Sahrawy Barragán (Granada, ES)
19:00 – 19:20 P03-28 Abiotic stress induced differential translation regulation in plants
Emilio Yángüez López-Cano (Pozuelo de Alarcón, Madrid, ES)
19:20 – 19:40 P03-30 Ear nitrogen metabolism and maize yield
Rafael A. Cañas (Málaga, ES)
19:40 – 20:00 P03-35 Redox control in the adaptation of plants to elevated light intensities
Marika Lindahl (Seville, ES)
20:00 – 20:20 P03-7 Nitric oxide regulation of stem cell niche homeostasis through auxin crosstalk
Luis Sanz (Villamayor, Salamanca, ES)
Selected Communications (10 min each)
20:20 – 20:30 P03r-8 Different approaches for the isolation of efficient promoters to direct the expression
of transgenes in microalgae
M. de la Vega Naranjo (Huelva, ES)
24

27. CONGRESS DETAILED PROGRAM
20:30 – 20:40 P03-21 Sulfide prevents early senescence and autophagy induction caused by DES1 deletion
in Arabidopsis thaliana
Cecilia Gotor (Sevilla, ES)
20:40 – 20:50 P03-33 Operon flv4-flv2 provides cyanobacteria with a novel photoprotection mechanism
Luca Bersanini (Turku, FI)
19:00 – 21:30 R03 Biomembranes and Bioenergetics
Room E Chairs: Ana M. Mata (Badajoz, ES) and Antonio Ferrer (Alicante, ES)
19:00 – 19:20 P05-37 Setting up a benchmark for the characterization of TRP channels
Alex Perálvarez-Marín (Cerdanyola del Vallés, ES)
19:20 – 19:40 P05-17 Lessons from reductionism on a membrane-active protein: Minimal pore-forming
versions of Bax
Jesús Salgado (Paterna, ES)
Selected Communications (10 min each)
19:40 – 19:50 P05-28 Sterols modulate vacuolar proton transport and autophagy in yeast
Agustin Hernandez (Sevilla, ES)
19:50 – 20:00 P05-15 The role of SCaMC-3, the mitochondrial transporter of ATP-Mg/Pi expressed
in liver and brain, in regulating OXPHOS
Ignacio Amigo (Madrid, ES)
20:00 – 20:10 P05-7 The PI(4,5)P2-binding site in C2 domains: a conserved motif with subtle variations
that modulate their membrane interactions
Senena Corbalán (Murcia, ES)
20:10 – 20:20 P05-11 Effect of cholesterol and palmitoylation on the structure, orientation and lipid-protein
interactions of pulmonary surfactant protein SP-C
Nuria Roldán López (Madrid, ES)
20:20 – 20:30 P05-9 Mitochondrial porin: a new subunit of the TIM22 protein translocase
Jorge L. Bermejo Vázquez (Cáceres, ES)
20:30 – 20:40 P05-31 Tethering of lipid membranes reorganizes the distribution of lipid domains
Fábio Fernandes (Lisbon, PT)
20:40 – 20:50 P05r-39 Cytochrome c1- cytochrome c: an atypical transient complex
Katiuska González-Arzola (Seville, ES)
19:00 – 21:30 R06 Free Radicals
Room F Chair: Consuelo Borrás Blasco (Valencia, ES)
19:00 – 19:30 P08-91 Lipid peroxidizability as a potential trade-off of increased tissular docosahexaenoic
acid concentrations in neurodegenerative processes
Manuel Portero-Otin (Lleida, ES)
19:30 – 20:00 P08-40 Why fatty liver does not respond to isquemic preconditioning?
Maria Monsalve (Madrid, ES)
20:00 – 20:30 P08-67 Gender differences in the fetal to neonatal transition: clinical and experimental data
Javier Escobar (Valencia, ES)
25

28. CONGRESS DETAILED PROGRAM
20:30 – 21:00 P08-81 Recycling of dysfunctional mitochondria in coenzyme Q deficiency
A. Rodríguez-Hernández (Sevilla, ES)
Selected Communications (15 min each)
21:00 – 21:15 P08-32 Study of the involvement of DJ-1 in autophagy. Importance of the Nrf2/Keap1 axis
E. Pizarro-Estrella (Cáceres, ES)
21:15 – 21:30 P08-30 Mutational and selective forces cooperate to shape sulphur-containing amino acids
content in mammalian mtDNA-encoded proteins
Juan Carlos Aledo (Málaga, ES)
19:00 – 21:30 R07 Membrane Transporters
Room G Chairs: Olga Martínez Augustín (Granada, ES) and Miquel Moretó (Barcelona, ES)
19:00 – 19:30 P11-26 Implications of altered glucose transport observed in glucose transporter deficiency
disease (GLUT1DS) on transport models
Richard Naftalin (London, UK)
19:30 – 20:00 P11-28 Towards the atomic structure of heteromeric amino acid transporters
Manuel Palacin Prieto (Barcelona, ES)
Selected Communications (10 min each)
20:00 – 20:10 P11r-4 Overexpression or lack of AQP1 in the cell membrane modify cell proliferation
associated to hypoxia
Ana Galán Cobo (Sevilla, ES)
20:10 – 20:20 P11r-17 Biogenesis and assembly of EmrE, a dual topology membrane protein
Pilar Lloris Garcerá (Stockholm, SE)
20:20 – 20:30 P11r-19 Effect of acetaminophen treatment on the role of export pumps ABCB1, ABCC1-4
and ABCG2 in the placental barrier
Ester González-Sánchez (Salamanca, ES)
19:00 – 21:30 R09 Molecular Bases of Pathology
Room A Chairs: Paloma Martín Sanz (Madrid, ES) and Ángela Martínez Valverde (Madrid, ES)
19:00 – 19:30 P13-114 Cardiotrophin 1 is a new molecular player in the mechanisms that control energy balance
Matilde Bustos de Abajo (Pamplona, ES)
19:30 – 20:00 P13-9 Cell death induced by inhibition of glucose metabolism: role of Bcl-2 proteins and autophagy
Cristina Muñoz-Pinedo (Hospitalet de Llobregat, ES)
Selected Communications (10 min each)
20:00 – 20:10 P13-116 A novel role for BMP9 as a protumorigenic factor in liver
Blanca Herrera (Madrid, ES)
20:10 – 20:20 P13r-20 Differentially expressed proteins and phosphoproteins of the pancreas during the early
phase of cerulein-induced acute pancreatitis. A 2-DE analysis
Violeta García-Hernández (Salamanca, ES)
20:20 – 20:30 P13-63 Mouse resistin modulates adipogenesis and glucose uptake in 3T3-L1 preadipocytes
through the ROR1 receptor
Victoriano Baladrón (Albacete, ES)
20:30 – 20:40 P13r-104 A novel inducible model for the study of PTEN-induced carcinogenesis
Cristina Mirantes Barbeito (Lleida, ES)
26

29. CONGRESS DETAILED PROGRAM
19:00 – 21:30 R10 Molecular Biotechnology
Room B Chair: Jesús M. Sanz (Elche, ES)
19:00 – 19:30 P14m-10 Biosynthesis of RNA polymerase inhibitor streptolydigin, pathway regulation
and generation of novel derivatives
Carlos Olano (Oviedo, ES)
19:30 – 20:00 P14-39 Exploring the cellulase diversity in Penicillium sp for 2nd generation bioethanol production
Laura Isabel de Eugenio (Madrid, ES)
Selected Communications (12 min each)
20:00 – 20:12 P 14-14 Transcriptome analysis shows activation of the arginine deiminase pathway
in Lactococcus lactis as a short-term adaptation to ethanol stress
Fernanda Ruiz-Larrea (Logroño, ES)
20:12 – 20:24 P14-15 Clues on protein amyloidosis from RepA-WH1, a synthetic bacterial prionoid
María Moreno-del Álamo (Madrid, ES)
20:24 – 20:36 P14-1 Self-bioremediation of cork-proccessing wastewaters by chloro-phenol degrading bacteria
immobilised onto residual cork particles
Eloísa Pajuelo (Sevilla, ES)
20:36 – 20:48 P14-24 Initial steps in deoxycholate and other bile salts catabolism in Pseudomonas sp. DOC21
Álvaro Barrientos (León, ES)
20:48 – 21:00 P14-35 Production and evaluation of polyclonal antibodies against alpha toxin oligomer from
Clostridium septicum
Lorena Vázquez-Iglesias (Vigo, ES)
19:00 – 21:30 R14 Nutritional Biochemistry
Room H Chair: Catalina Picó (Palma de Mallorca, ES)
19:00 – 19:25 P18-15 Epigenetic effects of diet: microRNAs and dietary flavonoids
Cinta Bladé (Tarragona, ES)
19:25 – 19:50 P18-26 Metabolic programming of obesity
Andreu Palou (Palma de Mallorca, ES)
19:50 – 20:15 P17m-19 Problems in the study of the nitrogen metabolism in the metabolic syndrome
Sofía Arriarán (Barcelona, ES)
Selected Communications (10 min each)
20:15 – 20:25 P18-1 Further study of genes involved in mouse steatotic liver identified by DNA microarray
Natalia Guillén Monzón (Zaragoza, ES)
20:25 – 20:35 P18-10 Effect of proinflammatory cytokine TNF- on Caveolin-1 gene methylation during
adipocyte differentiation. Relation to insulin signaling
Sara Palacios (Pamplona, ES)
20:35 – 20:45 P18r-23 Different health outcomes of prenatal and postnatal nutritional conditions affecting
obesity susceptibility may be related with different programming effects on similar
metabolic targets
Juana Sánchez (Palma de Mallorca, ES)
20:45 – 20:55 P18-24 Protective effects of melanoidins derived from dried apricots on oxidative damage
and mitochondrial-dependent endothelial cell death
Gianfranco Pintus (Sassari, IT)
27

30. CONGRESS DETAILED PROGRAM
19:00 – 21:30 R16 Protein Structure and Function
Auditorium Chair: Guillermo Montoya (Madrid, ES)
19:00 – 19:25 P20r-120 Crystal structures of the receptor-binding C-terminal domain of bacteriophage T4
and T7 tail fibres
Carmela García-Doval (Madrid, ES)
19:25 – 19:50 P20-163 Structural systems biology: combining structures and interactomes
Roberto Mosca (Barcelona, ES)
19:50 – 20:15 P20r-49 Molecular recognition mechanisms of microtubule plus end tracking proteins
Ruben Martinez Buey (Salamanca, ES)
20:15 – 20:40 P20-165 Structural and biochemical studies on multifunctional Bacillus cereus
MCM complex
Jasminka Boskovic (Madrid, ES)
20:40 – 21:05 P20-158 Inhibiting RAS interactions using peptides; computational design and experimental
validation
Narcis Fernandez-Fuentes (Aberystwyth, UK)
21:05 – 21:30 Entrega Premio José Tormo
Robert B. Fenwick (Barcelona, ES)
Thursday, September 6, 2012
08:30 – 10:25 S01 Single Molecules
Auditorium 01.2 Protein Networks
Chairs: Rita Bernhardt (Saarbruecken, DE) and Carlos Gómez-Moreno (Zaragoza, ES)
08:30 – 08:55 S01.2-1 A network medicine approach to human disease
Patrick Aloy (Barcelona, ES)
09:00 – 09:25 S01.2-2 Role of an adrenal ferredoxin in regulating steroid hormone biosynthesis
Rita Bernhardt (Saarbruecken, DE)
09:30 – 09:55 S01.2-3 Network topology complements sequence as a source of biological information
Natasa Przulj (London, UK)
10:00 – 10:25 S01.2-4 Molecular courtship: how proteins form transient complexes
Marcellus Ubbink (Leiden, NL)
08:30 – 10:25 S02 Trends in Biochemistry
Room F 02.2 Transcription and Chromatin
Chairs: Laszlo Tora (Illkirch, FR) and Sebastián Chávez (Sevilla, ES)
08:30 – 08:55 S02.2-1 Novel cellular players involved in transcription elongation
Sebastián Chávez (Seville, ES)
09:00 – 09:25 S02.2-2 An unexpected link between nuclear topography and chromatin structure regulates
HIV-1 integration and latency
Mauro Giacca (Trieste, IT)
28