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The CNS stimulants mostly produced a generalized action
which may
Produce convulsion at higher doses.
TYPE OF DRUGS NAME OF DRUGS
 ANALEPTICS PICROTOXIN,PENTYLENE
TETRAZOLE,MEDAFINIL,
DOXAZEPAM HYDROCHLORIDE.
 METHYLXANTHINES : CAFFINE,THEOPHYLLENE, THE
OBROMINE.
 CENTRAL SYMPATHOMIMETIC
AGENTS :
AMPHETAMINE,
METHAMPHETAMINE,
PHENTERMINE,BENZOPHETAMI
NE, FENFLURAMINE
 ANTIDEPRESSANTS :
a) MONO AMINE OXIASE INHIBITORS PHENELZINE
SULFATE,TRANYLCYPROMINE
SULFATE
b)TRICYCLIC ANTIDEPRESSANTS IMIPRAMINE,DESIMIPRAMINE,
CLOMIPRAMINE,
AMITRYPTILENE
1.The traditional analeptics are potent and non-selective.
2.They can be illustrated by
a)picrotoxin
& b) PTZ
3.BOTH OF THEM ARE OBSOLATED NOW.
4.But used in research purpose.
5.Newer agents
a)modafinil
& b)doxapram are selective
6.These two are used in narcolepsy and as respiratory
stimulant.
References :
1.Wilson & Gisvold’s Organic Medicinal and
Pharmaceutical chemistry
2.Essentials of Medical Pharmacology
-KD TRIPATHY
Presentation1stmulant cns

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Presentation1stmulant cns

  • 1.
  • 2. The CNS stimulants mostly produced a generalized action which may Produce convulsion at higher doses.
  • 3. TYPE OF DRUGS NAME OF DRUGS  ANALEPTICS PICROTOXIN,PENTYLENE TETRAZOLE,MEDAFINIL, DOXAZEPAM HYDROCHLORIDE.  METHYLXANTHINES : CAFFINE,THEOPHYLLENE, THE OBROMINE.  CENTRAL SYMPATHOMIMETIC AGENTS : AMPHETAMINE, METHAMPHETAMINE, PHENTERMINE,BENZOPHETAMI NE, FENFLURAMINE  ANTIDEPRESSANTS : a) MONO AMINE OXIASE INHIBITORS PHENELZINE SULFATE,TRANYLCYPROMINE SULFATE b)TRICYCLIC ANTIDEPRESSANTS IMIPRAMINE,DESIMIPRAMINE, CLOMIPRAMINE, AMITRYPTILENE
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  • 5. 1.The traditional analeptics are potent and non-selective. 2.They can be illustrated by a)picrotoxin & b) PTZ 3.BOTH OF THEM ARE OBSOLATED NOW. 4.But used in research purpose. 5.Newer agents a)modafinil & b)doxapram are selective 6.These two are used in narcolepsy and as respiratory stimulant.
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  • 20. References : 1.Wilson & Gisvold’s Organic Medicinal and Pharmaceutical chemistry 2.Essentials of Medical Pharmacology -KD TRIPATHY