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„Bluthochdruck als Todesursache Nr.1 nachhaltig senken!“ 
 
Permanent hoher ​Blutdruck​ stellt ein ernstzunehmendes Problem dar, das zunehmend mehr 
Menschen, tendenziell auch immer jüngere betrifft. ​Steigender Leistungsdruck​, ​denaturierte 
Ernährung​ (=Vitalstoffmangel!), ​Bewegungsmangel ​und nicht zuletzt 
Medikamenteneinnahme​ werden hierfür verantwortlich gemacht. 
 
Medikamentöse Therapie des Bluthochdrucks 
Ein hoher​ ​Blutdruck​ schädigt insbesondere die kleineren Blutgefäße, wie sie im Auge und in 
den Nieren vorkommen. Außerdem muss das Herz gegen einen erhöhten Blutdruck 
arbeiten, was mehr Kraft kostet und auf Dauer zur Schädigung des Herzens führen kann. 
Therapie durch Lebensumstellung 
Grundsätzliche Empfehlungen zu einer​ ​Blutdruck​ senkenden Lebensweise umfassen unter 
anderem Rauchstopp, eine Salz arme Diät, regelmäßige körperliche Aktivität, Senkung der 
Blutfettwerte und Normalisierung des Körpergewichts. Oft sind diese Maßnahmen aber 
entweder nicht durchführbar für Patienten oder sie helfen noch nicht ausreichend. In diesem 
Fall kann eine medikamentöse Therapie eingeleitet werden. 
Fünf Hauptgruppen in der Therapie von Bluthochdruck 
Als erste Wahl in der Behandlung von Bluthochdruck gelten: ACE­Hemmer und 
Angiotensin­1­Antagonisten,​ ​Calcium­Kanal­Blocker​, beta­Blocker und​ ​Diuretika 
(Entwässerungsmittel). Da beta­Blocker viele unangenehme Nebenwirkungen wie 
depressive Verstimmung, Verschlimmerung einer bestehenden Psoriasis (Schuppenflechte) 
und Erektionsprobleme vorweisen, werden sie in der Behandlung immer seltener eingesetzt. 
In manchen Ländern zählen sie bereits nicht mehr zu den Erstlinien­Medikamenten. 
ACE­Hemmer haben zusätzlich zu ihrer Blutdruck senkenden Wirkung noch eine 
Schutzfunktion für die Niere. Eine typische Nebenwirkung ist allerdings ein trockener 
Reizhusten. In seltenen Fällen tritt ein Angioödem (Schwellung im Gesicht) auf. 
Angiotensin­1­Rezeptorblocker (Sartane) wirken über einen sehr ähnlichen Mechanismus 
wie ACE­Hemmer ­ ein Reizhusten kommt allerdings nicht vor. 
Calciumantagonisten empfehlen sich, wenn zusätzlich zum Bluthochdruck noch andere 
Symptome wie zum Beispiel eine pAVK (periphere Arterielle Verschluss­Krankheit, 
"Schaufensterkrankheit") eine Rolle spielen. 
Diuretika wie die häufig verschriebenen Thiazide sind besonders günstig bei zusätzlicher 
Herzschwäche oder Osteoporose. Nicht empfohlen werden sie, wenn zusätzlich zum 
Bluthochdruck Stoffwechselstörungen wie Diabetes mellitus, Gicht oder erhöhte Blutfette 
bestehen. 
Zumeist wird eine Behandlung bei Bluthochdruck mit einer Mono­ oder 
Kombinationstherapie aus zwei Medikamenten in niedriger Dosierung begonnen. Üblich sind 
Kombinationen aus einem​ ​Diuretikum​ (Thiazid) mit einem Medikament aus einer der 
anderen Erstlinien­Gruppen. Auch eine Kombination aus einem Calcium­Antagonist mit 
beta­Blocker, ACE­Hemmer oder Sartan hat sich als günstig erwiesen. 
Medikamente der Reserve 
Als weitere Medikamente kommen periphere alpha­1­Blocker (Urapidil), zentrale 
Antisympathotonika (alpha­Methyl­Dopa kann sogar in der Schwangerschaft verabreicht 
werden),​ ​Vasodilatatoren​ ​(stellen die Gefäße weit, zum Beispiel Nitroprussid­Natrium) und 
Renin­Inhibitoren (Aliskiren) in Frage. 
Welche Therapie die beste ist, unterscheidet sich von Mensch zu Mensch. Eine ausführliche 
Beratung durch einen Arzt ist anzuraten. 
  
 
 

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„Bluthochdruck als Todesursache Nr.1 nachhaltig senken!“